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The map label for this gene is rhtC [H]

Identifier: 186476596

GI number: 186476596

Start: 2106778

End: 2107428

Strand: Direct

Name: rhtC [H]

Synonym: Bphy_1841

Alternate gene names: 186476596

Gene position: 2106778-2107428 (Clockwise)

Preceding gene: 186476595

Following gene: 186476597

Centisome position: 60.55

GC content: 65.28

Gene sequence:

>651_bases
ATGGGTCTTTCTCTTCAGCAATTCGCAATGGTCGCGGGCGCGCATCTGCTTGCGCTGCTCAGCCCAGGTCCGGACTTCTT
TCTGATCGCACGCAGCGCGCTGTTGCGCGGATGGCGTAAGACGGGCGCCGTATGCTTCGGCATCGCCTGCGCGAATGGCG
TGTTCATTGCACTCGCGCTCGGCGGTGTGGCCGCGCTGCATCGGCACGGCACCGCGTTCGCGCTCGTCCAGGCGGCAGGC
TGCGTGTATCTGTTCTATCTGGGCGGATTGATGCTGCGGCATGCCAGAGCCGCGTCGATCGGCACGCACGGTCAGGATCG
CACTTCCGCGCCAACGGCAAGCGCCTGGCTTGCACGCTTTGCCACAGGCTTCGCCTCCGCGATTCTCAATCCGAAGAACG
CGCTCTTCTATGCCAGCCTGTTCGCGTTGCTCGCGGCTCGCGACGCGCCCTTCGGCGCACAGATCGTCTACGGCGCGTGG
ATGTTCGTGGCCGTGTTCGGCTGGGATCTGCTCGTGGCAATGAGCATCGGACATCCGGCTGTCGTCGCGCGCTTCACGCG
CCACAGCGCGTCGATCGAGCGCGTGACGGGCGCCGTATTGCTCGCGATCGCAGCAAGCGTGCTGGCGATGCTCGCGCGCC
AGTGGTTATGA

Upstream 100 bases:

>100_bases
CGTCGGCCCATGAGCACAGCAACGGCGTAACGGCGCGCACTTTTCTTCAATATCTCCACGCGCCCGTCCAGCAGACTCCC
GGCACACACAAGGAGTCGAG

Downstream 100 bases:

>100_bases
AGATGTTGATCGGCGACCATGCCGCATCACCCATCGCCGCCGGTTGACGCCGGGACATCATCGATATCCGTGAAGCCGCG
ATACCCGCACCGCCGCAACA

Product: lysine exporter protein LysE/YggA

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MGLSLQQFAMVAGAHLLALLSPGPDFFLIARSALLRGWRKTGAVCFGIACANGVFIALALGGVAALHRHGTAFALVQAAG
CVYLFYLGGLMLRHARAASIGTHGQDRTSAPTASAWLARFATGFASAILNPKNALFYASLFALLAARDAPFGAQIVYGAW
MFVAVFGWDLLVAMSIGHPAVVARFTRHSASIERVTGAVLLAIAASVLAMLARQWL

Sequences:

>Translated_216_residues
MGLSLQQFAMVAGAHLLALLSPGPDFFLIARSALLRGWRKTGAVCFGIACANGVFIALALGGVAALHRHGTAFALVQAAG
CVYLFYLGGLMLRHARAASIGTHGQDRTSAPTASAWLARFATGFASAILNPKNALFYASLFALLAARDAPFGAQIVYGAW
MFVAVFGWDLLVAMSIGHPAVVARFTRHSASIERVTGAVLLAIAASVLAMLARQWL
>Mature_215_residues
GLSLQQFAMVAGAHLLALLSPGPDFFLIARSALLRGWRKTGAVCFGIACANGVFIALALGGVAALHRHGTAFALVQAAGC
VYLFYLGGLMLRHARAASIGTHGQDRTSAPTASAWLARFATGFASAILNPKNALFYASLFALLAARDAPFGAQIVYGAWM
FVAVFGWDLLVAMSIGHPAVVARFTRHSASIERVTGAVLLAIAASVLAMLARQWL

Specific function: Conducts the efflux of threonine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=200, Percent_Identity=28, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1786522, Length=192, Percent_Identity=23.4375, Blast_Score=67, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22658; Mature: 22527

Theoretical pI: Translated: 11.29; Mature: 11.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLSLQQFAMVAGAHLLALLSPGPDFFLIARSALLRGWRKTGAVCFGIACANGVFIALAL
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHH
GGVAALHRHGTAFALVQAAGCVYLFYLGGLMLRHARAASIGTHGQDRTSAPTASAWLARF
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
ATGFASAILNPKNALFYASLFALLAARDAPFGAQIVYGAWMFVAVFGWDLLVAMSIGHPA
HHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHH
VVARFTRHSASIERVTGAVLLAIAASVLAMLARQWL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GLSLQQFAMVAGAHLLALLSPGPDFFLIARSALLRGWRKTGAVCFGIACANGVFIALAL
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHH
GGVAALHRHGTAFALVQAAGCVYLFYLGGLMLRHARAASIGTHGQDRTSAPTASAWLARF
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
ATGFASAILNPKNALFYASLFALLAARDAPFGAQIVYGAWMFVAVFGWDLLVAMSIGHPA
HHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHH
VVARFTRHSASIERVTGAVLLAIAASVLAMLARQWL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]