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The map label for this gene is yaeL [C]

Identifier: 186476089

GI number: 186476089

Start: 1490693

End: 1492081

Strand: Reverse

Name: yaeL [C]

Synonym: Bphy_1331

Alternate gene names: 186476089

Gene position: 1492081-1490693 (Counterclockwise)

Preceding gene: 186476090

Following gene: 186476088

Centisome position: 42.89

GC content: 62.71

Gene sequence:

>1389_bases
ATGAACCTGCTGATCGAACTGGTCGCCTTCGCCGTCGCGATTGGCGTACTGGTGGTCGTCCATGAGTATGGCCACTACAG
CGTCGCGCGCCTGTGCGGCGTCAAGGTGCTGCGATTCTCGATCGGCTTCGGCAAGCCGCTCGCGCGTTGGGTCAGCAGGA
AGACGGGCACGGAGTGGACCATCGCGGCGTTGCCGCTGGGCGGCTACGTCAAAATGCTTGACGAGCGCGAAGAGGGTTCG
CCCATTGCGCCGGACGACTTGCCGCGTGCATTCAACCGTCAATCGGTGGGCAAGCGCATCGCGATCGTGGCGGCAGGCCC
GGTTGCCAACTTCATCCTTGCAATCGTGCTGTTCGCCGCGGTGTTCGCGACGGGCGTCACGGAACCCGCGGCGATCGTCG
CGGCGCCCGCGGCCGAAACGGCGGCTGCGCGCGCGGGCTTCGACGGCGGCGAGACCGTGGTGGCCGTGCGCGACGCGAAT
GCGGGCGAATCCGAGCCGGTTCGCTCATGGTCGGATCTGCGCTGGAAGATGCTGGGCGCCGCGTTCGATCACAAGCGCCT
CGTGCTGACCGCGAAGGACGCGCACGGCACTTTCGACTTTCCGCTCGACTTGCAGAACCTTTCCGAGAAGGAAGTCGATG
ACGAGTTCATGTCGCGTCTCGGCTTCGAGCCGGGCGGCGGCACGCTGTCGGTGGCGGGCGTGCAGTCCGGCAGCGCGGCA
CTGCAGGCGGGCCTGCGCACAGGTGACCGGATTCGCGCGATCGACGGTCATCCCGCTGATAACGCAACGACCTTCATTAA
CTACATCAAGTCGCATGCGGGCACGCCGATCGTGCTGCAAATCGAGCGCGGCGCAAAGAATCAGCAGGCGGGTGCATTAC
AGAATCTAACCATCGTGCCCGGCACGCAGCGCGATGAAACGACGGGCCAACCGGTCGGCCGGATCGGCGCAGAACTTGCG
ACCCAGGTGCCCTCCATCGACGTACGCTATGGTCCCGTCGAAAGCCTGCGGCTGGGCGTGCATCGCACGTGGGACCTTGC
TGTGTACTCGGTTCGGATGTTCGGCCGGATGATCGTCGGCGAAGCATCGCTAAAGAACCTGTCGGGTCCCGTTACCATCG
CGGACTACGCAGGCAAGAGCGCGAGACTCGGTCCATCAGCATTCCTTTCGTTCCTCGCGCTTGTCAGCATTAGCCTCGGC
GTGCTCAACCTTTTACCAATACCCGTATTAGACGGGGGGCATCTGTTATATTATCTGGTTGAAGCTGTTACCGGCAAAGC
CGTATCGGATCGCTGGCAGCTCGTTCTTCAAAGAGCGGGACTGGCTTGTATCGTCGCCTTGTCGGCGATCGCGCTGTTCA
ACGATCTTGCTCGTTTAATCCATTTTTAA

Upstream 100 bases:

>100_bases
GTCGATGCCGACGCCGCCGCGCGCCGCGCTGCCCACGCGTACATCGACGGATTGCCGGCGGGCGCTCGCCTTACGGAACG
CGCCGTCCAGTGAGGCGATT

Downstream 100 bases:

>100_bases
AGTGTCTGGCGGCGTACGATGACGCCCGCCTGACCTGATGCAGCTATACACACTGGGGAAGCACGTTGTTTAAACCTCAT
CGCTTTGTTCCAAAGACGGT

Product: membrane-associated zinc metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MNLLIELVAFAVAIGVLVVVHEYGHYSVARLCGVKVLRFSIGFGKPLARWVSRKTGTEWTIAALPLGGYVKMLDEREEGS
PIAPDDLPRAFNRQSVGKRIAIVAAGPVANFILAIVLFAAVFATGVTEPAAIVAAPAAETAAARAGFDGGETVVAVRDAN
AGESEPVRSWSDLRWKMLGAAFDHKRLVLTAKDAHGTFDFPLDLQNLSEKEVDDEFMSRLGFEPGGGTLSVAGVQSGSAA
LQAGLRTGDRIRAIDGHPADNATTFINYIKSHAGTPIVLQIERGAKNQQAGALQNLTIVPGTQRDETTGQPVGRIGAELA
TQVPSIDVRYGPVESLRLGVHRTWDLAVYSVRMFGRMIVGEASLKNLSGPVTIADYAGKSARLGPSAFLSFLALVSISLG
VLNLLPIPVLDGGHLLYYLVEAVTGKAVSDRWQLVLQRAGLACIVALSAIALFNDLARLIHF

Sequences:

>Translated_462_residues
MNLLIELVAFAVAIGVLVVVHEYGHYSVARLCGVKVLRFSIGFGKPLARWVSRKTGTEWTIAALPLGGYVKMLDEREEGS
PIAPDDLPRAFNRQSVGKRIAIVAAGPVANFILAIVLFAAVFATGVTEPAAIVAAPAAETAAARAGFDGGETVVAVRDAN
AGESEPVRSWSDLRWKMLGAAFDHKRLVLTAKDAHGTFDFPLDLQNLSEKEVDDEFMSRLGFEPGGGTLSVAGVQSGSAA
LQAGLRTGDRIRAIDGHPADNATTFINYIKSHAGTPIVLQIERGAKNQQAGALQNLTIVPGTQRDETTGQPVGRIGAELA
TQVPSIDVRYGPVESLRLGVHRTWDLAVYSVRMFGRMIVGEASLKNLSGPVTIADYAGKSARLGPSAFLSFLALVSISLG
VLNLLPIPVLDGGHLLYYLVEAVTGKAVSDRWQLVLQRAGLACIVALSAIALFNDLARLIHF
>Mature_462_residues
MNLLIELVAFAVAIGVLVVVHEYGHYSVARLCGVKVLRFSIGFGKPLARWVSRKTGTEWTIAALPLGGYVKMLDEREEGS
PIAPDDLPRAFNRQSVGKRIAIVAAGPVANFILAIVLFAAVFATGVTEPAAIVAAPAAETAAARAGFDGGETVVAVRDAN
AGESEPVRSWSDLRWKMLGAAFDHKRLVLTAKDAHGTFDFPLDLQNLSEKEVDDEFMSRLGFEPGGGTLSVAGVQSGSAA
LQAGLRTGDRIRAIDGHPADNATTFINYIKSHAGTPIVLQIERGAKNQQAGALQNLTIVPGTQRDETTGQPVGRIGAELA
TQVPSIDVRYGPVESLRLGVHRTWDLAVYSVRMFGRMIVGEASLKNLSGPVTIADYAGKSARLGPSAFLSFLALVSISLG
VLNLLPIPVLDGGHLLYYLVEAVTGKAVSDRWQLVLQRAGLACIVALSAIALFNDLARLIHF

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=467, Percent_Identity=41.1134903640257, Blast_Score=303, Evalue=1e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 49077; Mature: 49077

Theoretical pI: Translated: 7.75; Mature: 7.75

Prosite motif: PS50106 PDZ ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLLIELVAFAVAIGVLVVVHEYGHYSVARLCGVKVLRFSIGFGKPLARWVSRKTGTEWT
CHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEE
IAALPLGGYVKMLDEREEGSPIAPDDLPRAFNRQSVGKRIAIVAAGPVANFILAIVLFAA
EEEECCCHHHHHHHCCCCCCCCCCHHHHHHHCHHHCCCEEEEEECCHHHHHHHHHHHHHH
VFATGVTEPAAIVAAPAAETAAARAGFDGGETVVAVRDANAGESEPVRSWSDLRWKMLGA
HHHHCCCCCCCEEECCCHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHH
AFDHKRLVLTAKDAHGTFDFPLDLQNLSEKEVDDEFMSRLGFEPGGGTLSVAGVQSGSAA
HCCCCEEEEEEECCCCCCCCCCCHHHCCHHHCCHHHHHHCCCCCCCCEEEEEECCCCHHH
LQAGLRTGDRIRAIDGHPADNATTFINYIKSHAGTPIVLQIERGAKNQQAGALQNLTIVP
HHHHCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCEEECC
GTQRDETTGQPVGRIGAELATQVPSIDVRYGPVESLRLGVHRTWDLAVYSVRMFGRMIVG
CCCCCCCCCCCHHHHHHHHHHCCCCCEEECCCHHHHHHCCCCCHHHHHHHHHHHHHHHHC
EASLKNLSGPVTIADYAGKSARLGPSAFLSFLALVSISLGVLNLLPIPVLDGGHLLYYLV
CHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHH
EAVTGKAVSDRWQLVLQRAGLACIVALSAIALFNDLARLIHF
HHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNLLIELVAFAVAIGVLVVVHEYGHYSVARLCGVKVLRFSIGFGKPLARWVSRKTGTEWT
CHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEE
IAALPLGGYVKMLDEREEGSPIAPDDLPRAFNRQSVGKRIAIVAAGPVANFILAIVLFAA
EEEECCCHHHHHHHCCCCCCCCCCHHHHHHHCHHHCCCEEEEEECCHHHHHHHHHHHHHH
VFATGVTEPAAIVAAPAAETAAARAGFDGGETVVAVRDANAGESEPVRSWSDLRWKMLGA
HHHHCCCCCCCEEECCCHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHH
AFDHKRLVLTAKDAHGTFDFPLDLQNLSEKEVDDEFMSRLGFEPGGGTLSVAGVQSGSAA
HCCCCEEEEEEECCCCCCCCCCCHHHCCHHHCCHHHHHHCCCCCCCCEEEEEECCCCHHH
LQAGLRTGDRIRAIDGHPADNATTFINYIKSHAGTPIVLQIERGAKNQQAGALQNLTIVP
HHHHCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCEEECC
GTQRDETTGQPVGRIGAELATQVPSIDVRYGPVESLRLGVHRTWDLAVYSVRMFGRMIVG
CCCCCCCCCCCHHHHHHHHHHCCCCCEEECCCHHHHHHCCCCCHHHHHHHHHHHHHHHHC
EASLKNLSGPVTIADYAGKSARLGPSAFLSFLALVSISLGVLNLLPIPVLDGGHLLYYLV
CHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHH
EAVTGKAVSDRWQLVLQRAGLACIVALSAIALFNDLARLIHF
HHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]