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The map label for this gene is cynT [H]

Identifier: 186475941

GI number: 186475941

Start: 1323026

End: 1323730

Strand: Reverse

Name: cynT [H]

Synonym: Bphy_1176

Alternate gene names: 186475941

Gene position: 1323730-1323026 (Counterclockwise)

Preceding gene: 186475942

Following gene: 186475939

Centisome position: 38.05

GC content: 64.68

Gene sequence:

>705_bases
ATGTCGGACGATAGGCTCAACACCAGACGGCTTCGCGACCCCGCGAAATCGGACCTGCTGCATCTGCTGGACGGCGTCGA
GCAGTTCAGCGACGAAGTGTTTCCCGCCACCCAGGCCTTGTTCGAGAGCCTCGCCCAGGGGCAGGCACCGCACACGCTGT
TCATCACGTGCGCCGATTCGCGCGTGTCGCCGGAAATGATTACGCAAACGCATCCGGGCGAGCTCTTCGTTTGCCGCAAC
ATCGGTAATATCGTCCCGGCTTACGGCGAGATGCTGGGCGGTGTATCGGCTGTCGTCGAGTATGCGGTGATCGCGCTCAA
CGTGCGGCAGATTGTGATCTGCGGGCACAGCGACTGCGGCGCGATGCGCGGCCTCGCCGGCACGGCGCCGATGACGGCGG
AAGAGATGCCTACCGTCAACGCGTGGCTGCGCAACGCGGAGACGGCGCGCAGCGTCGTGCAGGCGCGCAATGTCGATAGC
GAGCATCGGGTGCAGGCGCTCGTCGAAGAAAACATCCGGCTGCAACTGATGCATCTGCGCACGCATCCGTCCGTCGCTGG
GCGGCTTGCGCAAAAACGGCTCGACGTGCAAGGGTGGGTGTACGACATCGGCCACGGACGCATCGCCGTGTTCAACGAGG
ACGACGACCGCTTCGAGAGCGTGGCCGAGGCGCGCGGAAGGCTTCAGCAACAGCAGGGCGGTTGA

Upstream 100 bases:

>100_bases
GGTTTTGCGGCGAGAACGTGACACGTGACTGACCACTGCCGCATTCCCGTCGTACACTCCCTTCCATCATCCAGAATCGC
TGCGAAGGGGGAACCGCTCC

Downstream 100 bases:

>100_bases
AGATCGCGATTGGGCGTCGTCGGCAGGCGAGACGATCGATGGCCGCACCCGCCCGTCGCCTGACGAGTCTTCAGTCGCTT
CAATCACCCATCGCCGCCGC

Product: carbonate dehydratase

Products: NA

Alternate protein names: Carbonate dehydratase [H]

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MSDDRLNTRRLRDPAKSDLLHLLDGVEQFSDEVFPATQALFESLAQGQAPHTLFITCADSRVSPEMITQTHPGELFVCRN
IGNIVPAYGEMLGGVSAVVEYAVIALNVRQIVICGHSDCGAMRGLAGTAPMTAEEMPTVNAWLRNAETARSVVQARNVDS
EHRVQALVEENIRLQLMHLRTHPSVAGRLAQKRLDVQGWVYDIGHGRIAVFNEDDDRFESVAEARGRLQQQQGG

Sequences:

>Translated_234_residues
MSDDRLNTRRLRDPAKSDLLHLLDGVEQFSDEVFPATQALFESLAQGQAPHTLFITCADSRVSPEMITQTHPGELFVCRN
IGNIVPAYGEMLGGVSAVVEYAVIALNVRQIVICGHSDCGAMRGLAGTAPMTAEEMPTVNAWLRNAETARSVVQARNVDS
EHRVQALVEENIRLQLMHLRTHPSVAGRLAQKRLDVQGWVYDIGHGRIAVFNEDDDRFESVAEARGRLQQQQGG
>Mature_233_residues
SDDRLNTRRLRDPAKSDLLHLLDGVEQFSDEVFPATQALFESLAQGQAPHTLFITCADSRVSPEMITQTHPGELFVCRNI
GNIVPAYGEMLGGVSAVVEYAVIALNVRQIVICGHSDCGAMRGLAGTAPMTAEEMPTVNAWLRNAETARSVVQARNVDSE
HRVQALVEENIRLQLMHLRTHPSVAGRLAQKRLDVQGWVYDIGHGRIAVFNEDDDRFESVAEARGRLQQQQGG

Specific function: Reversible Hydration Of Carbon Dioxide. Carbon Dioxide Formed In The Bicarbonate-Dependent Decomposition Of Cyanate By Cyanase (Cyns) Diffuses Out Of The Cell Faster Than It Would Be Hydrated To Bicarbonate, So The Apparent Function Of This Enzyme Is To C

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786534, Length=202, Percent_Identity=51.4851485148515, Blast_Score=202, Evalue=1e-53,
Organism=Escherichia coli, GI1786318, Length=184, Percent_Identity=34.7826086956522, Blast_Score=91, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI25147564, Length=237, Percent_Identity=27.8481012658228, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI115532990, Length=239, Percent_Identity=26.7782426778243, Blast_Score=81, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6324292, Length=174, Percent_Identity=30.4597701149425, Blast_Score=84, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24645213, Length=237, Percent_Identity=24.4725738396624, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 25798; Mature: 25666

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDDRLNTRRLRDPAKSDLLHLLDGVEQFSDEVFPATQALFESLAQGQAPHTLFITCADS
CCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCC
RVSPEMITQTHPGELFVCRNIGNIVPAYGEMLGGVSAVVEYAVIALNVRQIVICGHSDCG
CCCHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCHH
AMRGLAGTAPMTAEEMPTVNAWLRNAETARSVVQARNVDSEHRVQALVEENIRLQLMHLR
HHCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEEEC
THPSVAGRLAQKRLDVQGWVYDIGHGRIAVFNEDDDRFESVAEARGRLQQQQGG
CCCHHHHHHHHHHHCCCCEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SDDRLNTRRLRDPAKSDLLHLLDGVEQFSDEVFPATQALFESLAQGQAPHTLFITCADS
CCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCC
RVSPEMITQTHPGELFVCRNIGNIVPAYGEMLGGVSAVVEYAVIALNVRQIVICGHSDCG
CCCHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCHH
AMRGLAGTAPMTAEEMPTVNAWLRNAETARSVVQARNVDSEHRVQALVEENIRLQLMHLR
HHCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEEEC
THPSVAGRLAQKRLDVQGWVYDIGHGRIAVFNEDDDRFESVAEARGRLQQQQGG
CCCHHHHHHHHHHHCCCCEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]