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The map label for this gene is ampR [H]

Identifier: 186475930

GI number: 186475930

Start: 1305606

End: 1306508

Strand: Direct

Name: ampR [H]

Synonym: Bphy_1165

Alternate gene names: 186475930

Gene position: 1305606-1306508 (Clockwise)

Preceding gene: 186475926

Following gene: 186475940

Centisome position: 37.53

GC content: 66.22

Gene sequence:

>903_bases
ATGCGTCCCTATCTGCCCCTGAATGCGCTGCGCGCGTTCGAAGCGTCGGCACGGCATCTGAGTTTCACGCGAGCCGCGCT
CGAATTGAACGTCACGCAGGCAGCCGTGAGCCAACAGGTGCGGATGCTCGAGGAGCGCCTCGGCGCGACGCTCTTCAAGC
GCCTGCCGCGCGGACTCGCGATCACGGATGAAGGGCTCGCGCTACGCCCCGTGCTGAGCGACGCATTCGATCGCATCGAA
GCCGTGCTGCGGCAGTTCGAAGGCGGGCATTTTCACGAGGTGCTGACGGTCGGCGCGGTCGGCACCTTCGCAGTAGGCTG
GCTGATGCCGCGCATGAAAGCGTTTCGTGACGCGCATCCGTTCGTCGAGTTGCGCCTGATGACGAATAACAACCTGGTCG
ATCTCGGCGCGGAAGGTCTCGACTTCGCGATCCGCTTCGGCGACGGCACATGGCCTGGGTCGCGTGCGTCCAAGCTCTTC
GACGCGCCGCTGTCGGTGCTCTGCACGCCAGAGATCGCGCAACGCCTGCACACGCCCGCCGATCTCGCCGGCGAAACATT
GCTGCGCTCGTATCGCGCCGACGACTGGGCGAGCTGGTTCGCAGCAGCGGGCCTTGCGCCGCGCCCCGTGCGCGGGCCCG
TCTTCGATTCGTCGCGGCTGATGGTGGAAGCGGCCATGCAGGGCGCGGGAGTCGCGCTGGCGCCGGCATCGATGTTCGAA
CGTGATCTGTCGATGGGACGCCTTGCGTGCCCGTTCGCTATTCACGTGCACACGGGCAGCTACTGGCTCACCTGGCAAAA
GGCGAAGCCTGCGTCGCCCGCGATGCGCGCGTTCAGTCAGTGGCTCGCGACGGAAGCAGAGGGAATGGCGGAAGGGATCG
AATCGTCAGGCGAAGCGTCGTGA

Upstream 100 bases:

>100_bases
CATTGCTCCTCCTTGAAGAGCCGCCACTATCGCGTCTCCCCGGCGGGCTGACAAACGATGATAAATTGCTCGATGACCCA
GAAAATCTTATGACTCGAAC

Downstream 100 bases:

>100_bases
TGCACGCTTCACCCGGGTCACGCATCCTCACATCTCGGACAGATGCGCCGCTGCCGACGTCTCGCGCGGCTGTCCGCCGA
TCTTGATGTGCGGCACCATC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MRPYLPLNALRAFEASARHLSFTRAALELNVTQAAVSQQVRMLEERLGATLFKRLPRGLAITDEGLALRPVLSDAFDRIE
AVLRQFEGGHFHEVLTVGAVGTFAVGWLMPRMKAFRDAHPFVELRLMTNNNLVDLGAEGLDFAIRFGDGTWPGSRASKLF
DAPLSVLCTPEIAQRLHTPADLAGETLLRSYRADDWASWFAAAGLAPRPVRGPVFDSSRLMVEAAMQGAGVALAPASMFE
RDLSMGRLACPFAIHVHTGSYWLTWQKAKPASPAMRAFSQWLATEAEGMAEGIESSGEAS

Sequences:

>Translated_300_residues
MRPYLPLNALRAFEASARHLSFTRAALELNVTQAAVSQQVRMLEERLGATLFKRLPRGLAITDEGLALRPVLSDAFDRIE
AVLRQFEGGHFHEVLTVGAVGTFAVGWLMPRMKAFRDAHPFVELRLMTNNNLVDLGAEGLDFAIRFGDGTWPGSRASKLF
DAPLSVLCTPEIAQRLHTPADLAGETLLRSYRADDWASWFAAAGLAPRPVRGPVFDSSRLMVEAAMQGAGVALAPASMFE
RDLSMGRLACPFAIHVHTGSYWLTWQKAKPASPAMRAFSQWLATEAEGMAEGIESSGEAS
>Mature_300_residues
MRPYLPLNALRAFEASARHLSFTRAALELNVTQAAVSQQVRMLEERLGATLFKRLPRGLAITDEGLALRPVLSDAFDRIE
AVLRQFEGGHFHEVLTVGAVGTFAVGWLMPRMKAFRDAHPFVELRLMTNNNLVDLGAEGLDFAIRFGDGTWPGSRASKLF
DAPLSVLCTPEIAQRLHTPADLAGETLLRSYRADDWASWFAAAGLAPRPVRGPVFDSSRLMVEAAMQGAGVALAPASMFE
RDLSMGRLACPFAIHVHTGSYWLTWQKAKPASPAMRAFSQWLATEAEGMAEGIESSGEAS

Specific function: This protein is a positive regulator of gene expression of beta-lactamase (AmpC) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789173, Length=291, Percent_Identity=38.4879725085911, Blast_Score=199, Evalue=1e-52,
Organism=Escherichia coli, GI1786448, Length=289, Percent_Identity=31.1418685121107, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1788706, Length=298, Percent_Identity=31.2080536912752, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1786401, Length=279, Percent_Identity=25.4480286738351, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787128, Length=282, Percent_Identity=25.886524822695, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1787589, Length=255, Percent_Identity=27.0588235294118, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI145693193, Length=300, Percent_Identity=25, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI87081978, Length=290, Percent_Identity=26.8965517241379, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI157672245, Length=165, Percent_Identity=34.5454545454545, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32754; Mature: 32754

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPYLPLNALRAFEASARHLSFTRAALELNVTQAAVSQQVRMLEERLGATLFKRLPRGLA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
ITDEGLALRPVLSDAFDRIEAVLRQFEGGHFHEVLTVGAVGTFAVGWLMPRMKAFRDAHP
ECCCCCEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
FVELRLMTNNNLVDLGAEGLDFAIRFGDGTWPGSRASKLFDAPLSVLCTPEIAQRLHTPA
EEEEEEEECCCEEECCCCCCEEEEEECCCCCCCHHHHHHHHCCHHEEECHHHHHHHCCCH
DLAGETLLRSYRADDWASWFAAAGLAPRPVRGPVFDSSRLMVEAAMQGAGVALAPASMFE
HHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEECHHHHHH
RDLSMGRLACPFAIHVHTGSYWLTWQKAKPASPAMRAFSQWLATEAEGMAEGIESSGEAS
HHHHCCCEECCEEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRPYLPLNALRAFEASARHLSFTRAALELNVTQAAVSQQVRMLEERLGATLFKRLPRGLA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
ITDEGLALRPVLSDAFDRIEAVLRQFEGGHFHEVLTVGAVGTFAVGWLMPRMKAFRDAHP
ECCCCCEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
FVELRLMTNNNLVDLGAEGLDFAIRFGDGTWPGSRASKLFDAPLSVLCTPEIAQRLHTPA
EEEEEEEECCCEEECCCCCCEEEEEECCCCCCCHHHHHHHHCCHHEEECHHHHHHHCCCH
DLAGETLLRSYRADDWASWFAAAGLAPRPVRGPVFDSSRLMVEAAMQGAGVALAPASMFE
HHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEECHHHHHH
RDLSMGRLACPFAIHVHTGSYWLTWQKAKPASPAMRAFSQWLATEAEGMAEGIESSGEAS
HHHHCCCEECCEEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8064842 [H]