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The map label for this gene is yisV [H]

Identifier: 186475940

GI number: 186475940

Start: 1321540

End: 1322946

Strand: Direct

Name: yisV [H]

Synonym: Bphy_1175

Alternate gene names: 186475940

Gene position: 1321540-1322946 (Clockwise)

Preceding gene: 186475930

Following gene: 186475948

Centisome position: 37.98

GC content: 65.53

Gene sequence:

>1407_bases
ATGAAAATCACCCTCGACGTCGCAACGGCCACCCCGCTGACAGAACAGATCGTCGGCCAGGTCGAAGCACTGATCCTGTC
GCGCGAATTGCGCGTGGGCATGCGGCTGCCGTCCATCCGCAAGTTCGCGGCCGAGCACAACATCAGCCGCTTCCCCGTCA
TCGAGGCGTACGACCGGCTCGCCACGCGCGGCCTGCTCCAGCCCAAGCACGGCTCGGGCTATTACGTCGCCGAACAGTTC
GAAAAAGCGCCGCGCGCCACGCGCGGACTCGATGCGATTCGCGCGACGCCCGAGTCCGATCAGATCCTGCGGCAGTTCGA
GCGCCCCGACGAGGTGCTGAACCTGTCGATCGGCTTTATCCCCGAAGCATGGCGCGACGTCGAAGGCATCGCGCAGGCCA
TTCGCCAGGCGTCGCGCACGGACGCGCGCAGCCTGATCGACTATGCGATCCCGCAAGGCGACCCGGTGTTGCGGCTGCAG
ATCGAACAGCGCCTTGCCTTCGTCGGCGTCGCCGCGGAGCCGCAAAACATCATGGTCACGAACAGCGCGAGCGAGGCGCT
CGACCTCGTTGTGCGGATGCTGCTCAAACCCGGCGACACGGTATTCGTCGAAGATCCCGGCTATTTCAACCTGTTCGGGC
TGCTCAAACTGCAAGGGATCGAGCTGATCGGCGTACCGCGCCTGTCGACGGGGCCCGATGTCGACGCCGTCGAAGCGCTG
CTGAAAGCGCATCGGCCGAAGCTTTTCTTCCTCAACACCGTCTTTCACAACCCGACGGGCACGAACGTCGCGCCGCACGT
CGGCTTCCGGCTGCTACAGCTTGCGCAGGAACACGACTTCATGATCGTCGAAGACGACGTATACGCGGATTTCCAGGCGA
TCCCGACGCCGCGCCTCGCGTCGCTCGACCGGCTGACGCGCGTGCTGTACATCGGCGGGTTCTCAAAGAGCCTGTCGTCG
TCGCTGCGGCTCGGCTACATCGCGGCGGAAGCGGGACTGATCAAACACTTCGTCGAAGTGAAGGCGCTCACAAGCCTGGG
GGGCACGCGTTTTAGCGAGCGCGTCGTCGCGGCGCTGCTCGAACGCGGCACCTATCGCAAGCATCTGGAGCGGCTCAGAC
GCCGCGTGAACGGTGCGATTTCGACGGCCGTGGAACTGCTTTCCGAGATCGGCTGGCAGGTGTTCGACGAGCCCTGCGGC
GGCACGCTCGTGTGGGCGCGCGTGCCCGGCGTGCCGAATTCGGAGGTGTTCGTCGCGGAGGCGGCGCAGGCCGGCATCAC
GGTGCAGCCGGGCAGCTACTACCGGCCGCACGGCGAGCCGACGCCGTGGGTACGCTTCAATACCGCGTATCTCGACAACG
AGCGCGCAATGGGATTTTTGCGGCGCGCGGCGGCGATGGGTGATTGA

Upstream 100 bases:

>100_bases
CCTATTGTTCCGGTAAACTGCGAGAACTGGAATGAACACTTTCGATCAATTTGCGCGAAGTGTTCGGCAAACTTGCGCGA
ACACTTTGAACGGGAGGCGA

Downstream 100 bases:

>100_bases
AGCGACTGAAGACTCGTCAGGCGACGGGCGGGTGCGGCCATCGATCGTCTCGCCTGCCGACGACGCCCAATCGCGATCTT
CAACCGCCCTGCTGTTGCTG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MKITLDVATATPLTEQIVGQVEALILSRELRVGMRLPSIRKFAAEHNISRFPVIEAYDRLATRGLLQPKHGSGYYVAEQF
EKAPRATRGLDAIRATPESDQILRQFERPDEVLNLSIGFIPEAWRDVEGIAQAIRQASRTDARSLIDYAIPQGDPVLRLQ
IEQRLAFVGVAAEPQNIMVTNSASEALDLVVRMLLKPGDTVFVEDPGYFNLFGLLKLQGIELIGVPRLSTGPDVDAVEAL
LKAHRPKLFFLNTVFHNPTGTNVAPHVGFRLLQLAQEHDFMIVEDDVYADFQAIPTPRLASLDRLTRVLYIGGFSKSLSS
SLRLGYIAAEAGLIKHFVEVKALTSLGGTRFSERVVAALLERGTYRKHLERLRRRVNGAISTAVELLSEIGWQVFDEPCG
GTLVWARVPGVPNSEVFVAEAAQAGITVQPGSYYRPHGEPTPWVRFNTAYLDNERAMGFLRRAAAMGD

Sequences:

>Translated_468_residues
MKITLDVATATPLTEQIVGQVEALILSRELRVGMRLPSIRKFAAEHNISRFPVIEAYDRLATRGLLQPKHGSGYYVAEQF
EKAPRATRGLDAIRATPESDQILRQFERPDEVLNLSIGFIPEAWRDVEGIAQAIRQASRTDARSLIDYAIPQGDPVLRLQ
IEQRLAFVGVAAEPQNIMVTNSASEALDLVVRMLLKPGDTVFVEDPGYFNLFGLLKLQGIELIGVPRLSTGPDVDAVEAL
LKAHRPKLFFLNTVFHNPTGTNVAPHVGFRLLQLAQEHDFMIVEDDVYADFQAIPTPRLASLDRLTRVLYIGGFSKSLSS
SLRLGYIAAEAGLIKHFVEVKALTSLGGTRFSERVVAALLERGTYRKHLERLRRRVNGAISTAVELLSEIGWQVFDEPCG
GTLVWARVPGVPNSEVFVAEAAQAGITVQPGSYYRPHGEPTPWVRFNTAYLDNERAMGFLRRAAAMGD
>Mature_468_residues
MKITLDVATATPLTEQIVGQVEALILSRELRVGMRLPSIRKFAAEHNISRFPVIEAYDRLATRGLLQPKHGSGYYVAEQF
EKAPRATRGLDAIRATPESDQILRQFERPDEVLNLSIGFIPEAWRDVEGIAQAIRQASRTDARSLIDYAIPQGDPVLRLQ
IEQRLAFVGVAAEPQNIMVTNSASEALDLVVRMLLKPGDTVFVEDPGYFNLFGLLKLQGIELIGVPRLSTGPDVDAVEAL
LKAHRPKLFFLNTVFHNPTGTNVAPHVGFRLLQLAQEHDFMIVEDDVYADFQAIPTPRLASLDRLTRVLYIGGFSKSLSS
SLRLGYIAAEAGLIKHFVEVKALTSLGGTRFSERVVAALLERGTYRKHLERLRRRVNGAISTAVELLSEIGWQVFDEPCG
GTLVWARVPGVPNSEVFVAEAAQAGITVQPGSYYRPHGEPTPWVRFNTAYLDNERAMGFLRRAAAMGD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=294, Percent_Identity=25.5102040816327, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI33469970, Length=294, Percent_Identity=25.5102040816327, Blast_Score=106, Evalue=6e-23,
Organism=Escherichia coli, GI1790797, Length=434, Percent_Identity=29.0322580645161, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1787710, Length=463, Percent_Identity=28.2937365010799, Blast_Score=141, Evalue=9e-35,
Organism=Saccharomyces cerevisiae, GI6321236, Length=387, Percent_Identity=21.7054263565891, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI21356535, Length=259, Percent_Identity=25.0965250965251, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 51805; Mature: 51805

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITLDVATATPLTEQIVGQVEALILSRELRVGMRLPSIRKFAAEHNISRFPVIEAYDRL
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHH
ATRGLLQPKHGSGYYVAEQFEKAPRATRGLDAIRATPESDQILRQFERPDEVLNLSIGFI
HHHCCCCCCCCCCCHHHHHHHHCCHHHHCCHHHHCCCCHHHHHHHHCCCCHHEEEEECCC
PEAWRDVEGIAQAIRQASRTDARSLIDYAIPQGDPVLRLQIEQRLAFVGVAAEPQNIMVT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHEEEEEEECCCCCEEEE
NSASEALDLVVRMLLKPGDTVFVEDPGYFNLFGLLKLQGIELIGVPRLSTGPDVDAVEAL
CCHHHHHHHHHHHHHCCCCEEEEECCCCEEHEEHHEECCEEEEECCCCCCCCCHHHHHHH
LKAHRPKLFFLNTVFHNPTGTNVAPHVGFRLLQLAQEHDFMIVEDDVYADFQAIPTPRLA
HHHCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCHHCCCCCHHH
SLDRLTRVLYIGGFSKSLSSSLRLGYIAAEAGLIKHFVEVKALTSLGGTRFSERVVAALL
HHHHHHHHHHCCCCHHHHHCCHHEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
ERGTYRKHLERLRRRVNGAISTAVELLSEIGWQVFDEPCGGTLVWARVPGVPNSEVFVAE
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCEEEEEECCCCCCCCEEEEE
AAQAGITVQPGSYYRPHGEPTPWVRFNTAYLDNERAMGFLRRAAAMGD
CCCCCEEECCCCCCCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKITLDVATATPLTEQIVGQVEALILSRELRVGMRLPSIRKFAAEHNISRFPVIEAYDRL
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHH
ATRGLLQPKHGSGYYVAEQFEKAPRATRGLDAIRATPESDQILRQFERPDEVLNLSIGFI
HHHCCCCCCCCCCCHHHHHHHHCCHHHHCCHHHHCCCCHHHHHHHHCCCCHHEEEEECCC
PEAWRDVEGIAQAIRQASRTDARSLIDYAIPQGDPVLRLQIEQRLAFVGVAAEPQNIMVT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHEEEEEEECCCCCEEEE
NSASEALDLVVRMLLKPGDTVFVEDPGYFNLFGLLKLQGIELIGVPRLSTGPDVDAVEAL
CCHHHHHHHHHHHHHCCCCEEEEECCCCEEHEEHHEECCEEEEECCCCCCCCCHHHHHHH
LKAHRPKLFFLNTVFHNPTGTNVAPHVGFRLLQLAQEHDFMIVEDDVYADFQAIPTPRLA
HHHCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCHHCCCCCHHH
SLDRLTRVLYIGGFSKSLSSSLRLGYIAAEAGLIKHFVEVKALTSLGGTRFSERVVAALL
HHHHHHHHHHCCCCHHHHHCCHHEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
ERGTYRKHLERLRRRVNGAISTAVELLSEIGWQVFDEPCGGTLVWARVPGVPNSEVFVAE
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCEEEEEECCCCCCCCEEEEE
AAQAGITVQPGSYYRPHGEPTPWVRFNTAYLDNERAMGFLRRAAAMGD
CCCCCEEECCCCCCCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]