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The map label for this gene is ompR [H]

Identifier: 186475768

GI number: 186475768

Start: 1124931

End: 1125665

Strand: Reverse

Name: ompR [H]

Synonym: Bphy_1003

Alternate gene names: 186475768

Gene position: 1125665-1124931 (Counterclockwise)

Preceding gene: 186475771

Following gene: 186475767

Centisome position: 32.35

GC content: 61.9

Gene sequence:

>735_bases
ATGCCGACCATGGAAACCAAAAACCCTTCGAAAATCCTCGTCGTCGATGACGACCCGCGTCTGCGTGACCTGCTGCGCCG
TTACCTCGGCGAGCAGGGGTTTAACGTTTATGTAGCCGAAAACGCACCGTCGATGAACAAGCTGTGGGTGCGCGAACGTT
TCGATCTGCTGGTGCTCGATCTGATGCTGCCGGGGGAAGACGGTCTTTCAATCTGCCGGCGGCTGCGTGGCAGCAACGAC
CGCACGCCGATCATCATGTTGACGGCCAAGGGTGAGGACGTGGATCGCATCGTTGGCCTGGAAATGGGCGCCGACGACTA
TCTGCCGAAGCCATTCAATCCGCGCGAGCTCGTCGCGCGCATTCACGCGGTGCTGCGTCGCCAGTCGCCGTCCGAACTGC
CGGGCGCGCCGTCGGAAACCTCCGAAGTGTTCGAGTTCGGCGAGTTCGCGCTGAACCTCGCAACGCGAACGCTCACCAAG
GCCGGCCAGGAAATTCCCCTGACGACGGGCGAGTTTTCCGTTCTGAAGGTGTTCGCGCGTCATCCGCGCCAACCGCTGTC
GCGCGAAAAGCTGATGGAACTCGCGCGCGGCCGTGAATATGAAGTTTTCGACCGCAGTCTCGACGTGCAGATCTCCCGTC
TGCGGAAACTGATCGAACCGGATCCGGGCAGCCCGCGCTTCATCCAGACGGTGTGGGGTCTCGGCTACGTGTTCATTCCC
GACGGCGCCGCCTGA

Upstream 100 bases:

>100_bases
GCGCCGAGGCTTTACGCCGTGCCACAGGCCGGGTAAATTTTGTAACTGACTGTTACGTGATAAATGGTGCAAACGCGCAC
CTCTTTCTAATCGCGCTAAG

Downstream 100 bases:

>100_bases
GTTTGCCGTTCCAGTTGTCTCTCTTTTTTGACACGAAGGCCGCATGCGGATCGACCGGCGCCTACTGACGCTCGCATTCG
GCGGTCTGTTCTGGCGAACG

Product: osmolarity response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MPTMETKNPSKILVVDDDPRLRDLLRRYLGEQGFNVYVAENAPSMNKLWVRERFDLLVLDLMLPGEDGLSICRRLRGSND
RTPIIMLTAKGEDVDRIVGLEMGADDYLPKPFNPRELVARIHAVLRRQSPSELPGAPSETSEVFEFGEFALNLATRTLTK
AGQEIPLTTGEFSVLKVFARHPRQPLSREKLMELARGREYEVFDRSLDVQISRLRKLIEPDPGSPRFIQTVWGLGYVFIP
DGAA

Sequences:

>Translated_244_residues
MPTMETKNPSKILVVDDDPRLRDLLRRYLGEQGFNVYVAENAPSMNKLWVRERFDLLVLDLMLPGEDGLSICRRLRGSND
RTPIIMLTAKGEDVDRIVGLEMGADDYLPKPFNPRELVARIHAVLRRQSPSELPGAPSETSEVFEFGEFALNLATRTLTK
AGQEIPLTTGEFSVLKVFARHPRQPLSREKLMELARGREYEVFDRSLDVQISRLRKLIEPDPGSPRFIQTVWGLGYVFIP
DGAA
>Mature_243_residues
PTMETKNPSKILVVDDDPRLRDLLRRYLGEQGFNVYVAENAPSMNKLWVRERFDLLVLDLMLPGEDGLSICRRLRGSNDR
TPIIMLTAKGEDVDRIVGLEMGADDYLPKPFNPRELVARIHAVLRRQSPSELPGAPSETSEVFEFGEFALNLATRTLTKA
GQEIPLTTGEFSVLKVFARHPRQPLSREKLMELARGREYEVFDRSLDVQISRLRKLIEPDPGSPRFIQTVWGLGYVFIPD
GAA

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=233, Percent_Identity=68.2403433476395, Blast_Score=328, Evalue=1e-91,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=43.7229437229437, Blast_Score=157, Evalue=7e-40,
Organism=Escherichia coli, GI1786599, Length=236, Percent_Identity=43.6440677966102, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1786784, Length=233, Percent_Identity=37.7682403433476, Blast_Score=151, Evalue=3e-38,
Organism=Escherichia coli, GI1788394, Length=238, Percent_Identity=36.9747899159664, Blast_Score=151, Evalue=5e-38,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=34.051724137931, Blast_Score=144, Evalue=4e-36,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=37.4468085106383, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1787229, Length=234, Percent_Identity=35.042735042735, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1790860, Length=230, Percent_Identity=36.0869565217391, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1786911, Length=230, Percent_Identity=33.0434782608696, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=32.0175438596491, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI87082012, Length=230, Percent_Identity=30.4347826086957, Blast_Score=113, Evalue=9e-27,
Organism=Escherichia coli, GI1787375, Length=232, Percent_Identity=34.051724137931, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1790552, Length=234, Percent_Identity=34.6153846153846, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1788550, Length=144, Percent_Identity=29.8611111111111, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1790299, Length=123, Percent_Identity=30.0813008130081, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788905, Length=126, Percent_Identity=30.1587301587302, Blast_Score=63, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=116, Percent_Identity=31.0344827586207, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27663; Mature: 27532

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTMETKNPSKILVVDDDPRLRDLLRRYLGEQGFNVYVAENAPSMNKLWVRERFDLLVLD
CCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCEEEEE
LMLPGEDGLSICRRLRGSNDRTPIIMLTAKGEDVDRIVGLEMGADDYLPKPFNPRELVAR
EECCCCHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHEEECCCCCCCCCCCCHHHHHHH
IHAVLRRQSPSELPGAPSETSEVFEFGEFALNLATRTLTKAGQEIPLTTGEFSVLKVFAR
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
HPRQPLSREKLMELARGREYEVFDRSLDVQISRLRKLIEPDPGSPRFIQTVWGLGYVFIP
CCCCCCCHHHHHHHHCCCCEEHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEEC
DGAA
CCCC
>Mature Secondary Structure 
PTMETKNPSKILVVDDDPRLRDLLRRYLGEQGFNVYVAENAPSMNKLWVRERFDLLVLD
CCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCEEEEE
LMLPGEDGLSICRRLRGSNDRTPIIMLTAKGEDVDRIVGLEMGADDYLPKPFNPRELVAR
EECCCCHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHEEECCCCCCCCCCCCHHHHHHH
IHAVLRRQSPSELPGAPSETSEVFEFGEFALNLATRTLTKAGQEIPLTTGEFSVLKVFAR
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
HPRQPLSREKLMELARGREYEVFDRSLDVQISRLRKLIEPDPGSPRFIQTVWGLGYVFIP
CCCCCCCHHHHHHHHCCCCEEHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEEC
DGAA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]