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The map label for this gene is qor [H]

Identifier: 186475723

GI number: 186475723

Start: 1070205

End: 1071179

Strand: Reverse

Name: qor [H]

Synonym: Bphy_0958

Alternate gene names: 186475723

Gene position: 1071179-1070205 (Counterclockwise)

Preceding gene: 186475729

Following gene: 186475715

Centisome position: 30.79

GC content: 67.69

Gene sequence:

>975_bases
ATGCGCGCAATCCGCTGCAACCAGTACGGCCCACCCGAAACGCTAAGCATCGAGGAACTGCCCGACCTCGTGCCGCAAGC
CGGTCAGATCGCGATCGACGTGAAAGCGGCGAGCGTCAACTTTCCCGACGTGCTGATCATCCAGAACAGGTACCAGTTCA
AGCCGTCCCTGCCATTCACGCCCGGCGCGGAGGTGGCGGGCATCGTGCGCGCCGTCGGCGACGGTGTGACGCAGTTCAAG
CCCGGCATGCGCGTGGTCGCGTACACGCAACAAGGCGGTTTCGCCGAGCAGGCGGTCGCCGACGCCGGCGCGTGCGTGCC
CCTGGCCGACGACGCCGATCTCGAAGCAGCCGCCGTCCTCACGCTCGCGTATGGCACGTCGCATCACGCCGTAGTCGACC
GCGCGGCATTGAAAGCGGGCGAAACGATGCTCGTACTCGGCGCGGCGGGCGGCGTCGGCCTCGCCGCGGTCGAAATCGGC
AAGGCGCTCGGCGCGCGCGTGATTGCGGCGGCATCCAGCGACGAGAAGCTCGCGACCTGCGTCGCGCACGGTGCGGACGC
AACCATCAATTACGCGACGGAAGACCTGCGCGAACGCATCAAGGCGCTCACGGACGGCAACGGCCCCGACGTGATCTACG
ATCCCGTCGGCGGCAGCTATGCGGAGCCCGCATTTCGCAGCATCGGCTGGCGCGGGCGCTATCTCGTGGTCGGCTTTGCG
AACGGCGAAATTCCAAAGCTGCCGCTCAATCTCGCGCTGCTGAAAGGCGCGAGCATCGTCGGCGTGTTCTGGGGCGAATT
CGCGCGCCGCGAGCCCCAGCGCAATGCCGCCGCCTTTCAGGAGATGCTCGGCTGGATTCGCGCCGGCAAACTGAGGCCGC
TGGTATCGGCGCGCTATCCGCTCGAGGACACGGCGCGCGCGCTCAACGACATGGCGCAGCGGCGCGTGCTCGGCAAGATC
GTCATCACGCCCTGA

Upstream 100 bases:

>100_bases
TGCCAAGACGCGACGAGCCAGCCTGCAGATCGAAAGCACGCTTGTGAAGCGTGCATGAACCCGTGATGTTTGCACCACAC
ACTTATCGATGGGAGACACG

Downstream 100 bases:

>100_bases
GCACTGTGTTGCCCCGAAAAGCAAAACGGCGCGTGGCCTTAGCGAGGCCACGCGCCGTTTGTTACCCGCCATCGAACGCA
GTCAGATTTTTTCCGTCTCG

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MRAIRCNQYGPPETLSIEELPDLVPQAGQIAIDVKAASVNFPDVLIIQNRYQFKPSLPFTPGAEVAGIVRAVGDGVTQFK
PGMRVVAYTQQGGFAEQAVADAGACVPLADDADLEAAAVLTLAYGTSHHAVVDRAALKAGETMLVLGAAGGVGLAAVEIG
KALGARVIAAASSDEKLATCVAHGADATINYATEDLRERIKALTDGNGPDVIYDPVGGSYAEPAFRSIGWRGRYLVVGFA
NGEIPKLPLNLALLKGASIVGVFWGEFARREPQRNAAAFQEMLGWIRAGKLRPLVSARYPLEDTARALNDMAQRRVLGKI
VITP

Sequences:

>Translated_324_residues
MRAIRCNQYGPPETLSIEELPDLVPQAGQIAIDVKAASVNFPDVLIIQNRYQFKPSLPFTPGAEVAGIVRAVGDGVTQFK
PGMRVVAYTQQGGFAEQAVADAGACVPLADDADLEAAAVLTLAYGTSHHAVVDRAALKAGETMLVLGAAGGVGLAAVEIG
KALGARVIAAASSDEKLATCVAHGADATINYATEDLRERIKALTDGNGPDVIYDPVGGSYAEPAFRSIGWRGRYLVVGFA
NGEIPKLPLNLALLKGASIVGVFWGEFARREPQRNAAAFQEMLGWIRAGKLRPLVSARYPLEDTARALNDMAQRRVLGKI
VITP
>Mature_324_residues
MRAIRCNQYGPPETLSIEELPDLVPQAGQIAIDVKAASVNFPDVLIIQNRYQFKPSLPFTPGAEVAGIVRAVGDGVTQFK
PGMRVVAYTQQGGFAEQAVADAGACVPLADDADLEAAAVLTLAYGTSHHAVVDRAALKAGETMLVLGAAGGVGLAAVEIG
KALGARVIAAASSDEKLATCVAHGADATINYATEDLRERIKALTDGNGPDVIYDPVGGSYAEPAFRSIGWRGRYLVVGFA
NGEIPKLPLNLALLKGASIVGVFWGEFARREPQRNAAAFQEMLGWIRAGKLRPLVSARYPLEDTARALNDMAQRRVLGKI
VITP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=315, Percent_Identity=33.968253968254, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI13236495, Length=315, Percent_Identity=33.968253968254, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI194239676, Length=315, Percent_Identity=32.3809523809524, Blast_Score=148, Evalue=7e-36,
Organism=Homo sapiens, GI18379349, Length=311, Percent_Identity=28.2958199356913, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI22538446, Length=328, Percent_Identity=28.0487804878049, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI22538444, Length=328, Percent_Identity=28.0487804878049, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI24308257, Length=348, Percent_Identity=25.2873563218391, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI28557745, Length=326, Percent_Identity=29.7546012269939, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI197927207, Length=183, Percent_Identity=31.6939890710383, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI67078404, Length=332, Percent_Identity=25.3012048192771, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI67078406, Length=296, Percent_Identity=26.6891891891892, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI41872631, Length=296, Percent_Identity=25.3378378378378, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI47519420, Length=362, Percent_Identity=26.5193370165746, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1790485, Length=330, Percent_Identity=33.9393939393939, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI226510941, Length=331, Percent_Identity=24.773413897281, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17536829, Length=308, Percent_Identity=25.6493506493506, Blast_Score=88, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17507255, Length=325, Percent_Identity=25.8461538461538, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6319520, Length=328, Percent_Identity=28.9634146341463, Blast_Score=120, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6324486, Length=294, Percent_Identity=26.1904761904762, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6323961, Length=294, Percent_Identity=25.5102040816327, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323729, Length=337, Percent_Identity=23.4421364985163, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24581345, Length=249, Percent_Identity=24.0963855421687, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19920632, Length=254, Percent_Identity=24.8031496062992, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI221330659, Length=254, Percent_Identity=24.8031496062992, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI45550423, Length=306, Percent_Identity=24.1830065359477, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34174; Mature: 34174

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAIRCNQYGPPETLSIEELPDLVPQAGQIAIDVKAASVNFPDVLIIQNRYQFKPSLPFT
CCCEECCCCCCCCCCCHHHHHHHCCCCCCEEEEEEEEECCCCEEEEEECCEEECCCCCCC
PGAEVAGIVRAVGDGVTQFKPGMRVVAYTQQGGFAEQAVADAGACVPLADDADLEAAAVL
CCHHHHHHHHHHCCCHHHCCCCCEEEEEECCCCCHHHHHHCCCCEEECCCCCCCCCEEEE
TLAYGTSHHAVVDRAALKAGETMLVLGAAGGVGLAAVEIGKALGARVIAAASSDEKLATC
EEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCEEEEECCCCCHHHHH
VAHGADATINYATEDLRERIKALTDGNGPDVIYDPVGGSYAEPAFRSIGWRGRYLVVGFA
HHCCCCCEEEHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHCCCCCCEEEEEEC
NGEIPKLPLNLALLKGASIVGVFWGEFARREPQRNAAAFQEMLGWIRAGKLRPLVSARYP
CCCCCCCCCEEEEECCCCEEEHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHCCCC
LEDTARALNDMAQRRVLGKIVITP
HHHHHHHHHHHHHHHHHCEEEECC
>Mature Secondary Structure
MRAIRCNQYGPPETLSIEELPDLVPQAGQIAIDVKAASVNFPDVLIIQNRYQFKPSLPFT
CCCEECCCCCCCCCCCHHHHHHHCCCCCCEEEEEEEEECCCCEEEEEECCEEECCCCCCC
PGAEVAGIVRAVGDGVTQFKPGMRVVAYTQQGGFAEQAVADAGACVPLADDADLEAAAVL
CCHHHHHHHHHHCCCHHHCCCCCEEEEEECCCCCHHHHHHCCCCEEECCCCCCCCCEEEE
TLAYGTSHHAVVDRAALKAGETMLVLGAAGGVGLAAVEIGKALGARVIAAASSDEKLATC
EEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCEEEEECCCCCHHHHH
VAHGADATINYATEDLRERIKALTDGNGPDVIYDPVGGSYAEPAFRSIGWRGRYLVVGFA
HHCCCCCEEEHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHCCCCCCEEEEEEC
NGEIPKLPLNLALLKGASIVGVFWGEFARREPQRNAAAFQEMLGWIRAGKLRPLVSARYP
CCCCCCCCCEEEEECCCCEEEHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHCCCC
LEDTARALNDMAQRRVLGKIVITP
HHHHHHHHHHHHHHHHHCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]