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The map label for this gene is arnA [H]

Identifier: 186475688

GI number: 186475688

Start: 1025110

End: 1026156

Strand: Reverse

Name: arnA [H]

Synonym: Bphy_0923

Alternate gene names: 186475688

Gene position: 1026156-1025110 (Counterclockwise)

Preceding gene: 186475689

Following gene: 186475687

Centisome position: 29.49

GC content: 60.55

Gene sequence:

>1047_bases
ATGAAAAAAGTCCTGATTCTGGGTGTGAACGGCTTTATCGGCCATCACCTGTCCAAGCGCATTCTCGAAACGACCGACTG
GGAAGTGTTCGGGATGGACATGCAAACCGAGCGCCTCGGCGACCTCGTGAAACACGAGCGCATGCATTTCTTCGAGGGCG
ACATCACGATCAACAAGGAGTGGGTCGAGTATCACGTGAAGAAGTGCGACGTGATCCTGCCGCTCGTCGCGATCGCCACG
CCTGCCACGTACGTGCAGCAGCCGCTGCGCGTGTTCGAACTGGACTTCGAGGCGAACCTGCCCATCGTCCGTTCGGCTGT
GAAGTACGGCAAGCATCTCGTCTTCCCGTCAACTTCGGAAGTCTATGGCATGTGCTCGGACGAGCAGTTCGATCCCGACG
CGTCCGCCCTCACCTATGGTCCGATCAACAAGCCGCGCTGGATCTACGCGTGCTCGAAGCAGTTGATGGACCGCGTGATC
TGGGGCTACGGCATGGAAGGCCTCAACTTCACGCTGTTCCGTCCGTTCAACTGGATCGGCCCGGGCCTCGACTCGATCTA
CACGCCGAAGGAAGGTTCGTCGCGCGTGGTCACGCAGTTCCTCGGCCATATCGTGCGCGGCGAGAACATCAGTCTGGTCG
ACGGCGGCGCGCAGAAGCGCGCGTTCACCGATATCGACGACGGCATCAGCGCGCTGATGAAGATCATCGAGAACAAGAAC
GGCGTCGCGTCGGGCAAGATCTACAACATCGGCAATCCGACCAACAACTTCTCGGTGCGCGAACTCGCGCACAAGATGCT
GGCGCTGGCGGCCGAATTCCCCGAGTACGCGGAGTCGGCGAAGAAGGTGCAGCTCGTCGAAACGTCGTCGGGCGCGTATT
ACGGCGCTGGCTACCAGGACGTGCAGAACCGCGTGCCGAAGATCGACAACACGAAGCAGGAACTCGCCTGGGCGCCGCAG
TCGACGTTCGACGAAGCCCTGCGCAAGATCTTCGAAGCGTACCGCGGCCATGTCGCCGAAGCCCGCGCGCTCGTCGAACA
ACAATAA

Upstream 100 bases:

>100_bases
GCGTGATCGCCATCCACGAATTGCGGCATCAGCGCGACGGCAACGAGCGCGTCGTCACCCCCGCCGAATTCACCCAGTTC
ACTCAATCTTCCCGTAACGC

Downstream 100 bases:

>100_bases
GGGCTGCCGCTCTTGGCCTTGATCGTCCTGAAGATCGATGTCGATACGTTGCGTGGCACGCGTGAAGGCGTGCCCAATCT
CGCGCGTATCTTCGACCGCT

Product: NAD-dependent epimerase/dehydratase family protein

Products: NA

Alternate protein names: UDP-4-amino-4-deoxy-L-arabinose formyltransferase; ArnAFT; UDP-L-Ara4N formyltransferase; UDP-glucuronic acid oxidase, UDP-4-keto-hexauronic acid decarboxylating; ArnADH; UDP-GlcUA decarboxylase; UDP-glucuronic acid dehydrogenase [H]

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MKKVLILGVNGFIGHHLSKRILETTDWEVFGMDMQTERLGDLVKHERMHFFEGDITINKEWVEYHVKKCDVILPLVAIAT
PATYVQQPLRVFELDFEANLPIVRSAVKYGKHLVFPSTSEVYGMCSDEQFDPDASALTYGPINKPRWIYACSKQLMDRVI
WGYGMEGLNFTLFRPFNWIGPGLDSIYTPKEGSSRVVTQFLGHIVRGENISLVDGGAQKRAFTDIDDGISALMKIIENKN
GVASGKIYNIGNPTNNFSVRELAHKMLALAAEFPEYAESAKKVQLVETSSGAYYGAGYQDVQNRVPKIDNTKQELAWAPQ
STFDEALRKIFEAYRGHVAEARALVEQQ

Sequences:

>Translated_348_residues
MKKVLILGVNGFIGHHLSKRILETTDWEVFGMDMQTERLGDLVKHERMHFFEGDITINKEWVEYHVKKCDVILPLVAIAT
PATYVQQPLRVFELDFEANLPIVRSAVKYGKHLVFPSTSEVYGMCSDEQFDPDASALTYGPINKPRWIYACSKQLMDRVI
WGYGMEGLNFTLFRPFNWIGPGLDSIYTPKEGSSRVVTQFLGHIVRGENISLVDGGAQKRAFTDIDDGISALMKIIENKN
GVASGKIYNIGNPTNNFSVRELAHKMLALAAEFPEYAESAKKVQLVETSSGAYYGAGYQDVQNRVPKIDNTKQELAWAPQ
STFDEALRKIFEAYRGHVAEARALVEQQ
>Mature_348_residues
MKKVLILGVNGFIGHHLSKRILETTDWEVFGMDMQTERLGDLVKHERMHFFEGDITINKEWVEYHVKKCDVILPLVAIAT
PATYVQQPLRVFELDFEANLPIVRSAVKYGKHLVFPSTSEVYGMCSDEQFDPDASALTYGPINKPRWIYACSKQLMDRVI
WGYGMEGLNFTLFRPFNWIGPGLDSIYTPKEGSSRVVTQFLGHIVRGENISLVDGGAQKRAFTDIDDGISALMKIIENKN
GVASGKIYNIGNPTNNFSVRELAHKMLALAAEFPEYAESAKKVQLVETSSGAYYGAGYQDVQNRVPKIDNTKQELAWAPQ
STFDEALRKIFEAYRGHVAEARALVEQQ

Specific function: Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabin

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the sugar epimerase family. UDP-glucuronic acid decarboxylase subfamily [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=341, Percent_Identity=26.099706744868, Blast_Score=101, Evalue=1e-21,
Organism=Escherichia coli, GI1788589, Length=336, Percent_Identity=56.547619047619, Blast_Score=385, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI17539532, Length=344, Percent_Identity=22.9651162790698, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21356223, Length=350, Percent_Identity=24.5714285714286, Blast_Score=85, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021168
- InterPro:   IPR001509
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase; PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.13; =1.1.1.305 [H]

Molecular weight: Translated: 39206; Mature: 39206

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVLILGVNGFIGHHLSKRILETTDWEVFGMDMQTERLGDLVKHERMHFFEGDITINKE
CCEEEEEECCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHEEECCEEECHH
WVEYHVKKCDVILPLVAIATPATYVQQPLRVFELDFEANLPIVRSAVKYGKHLVFPSTSE
HHHHHHHHHHHHHHHHHHHCCHHHHHCCHHEEEECCCCCCHHHHHHHHHCCEEECCCCHH
VYGMCSDEQFDPDASALTYGPINKPRWIYACSKQLMDRVIWGYGMEGLNFTLFRPFNWIG
HHCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCC
PGLDSIYTPKEGSSRVVTQFLGHIVRGENISLVDGGAQKRAFTDIDDGISALMKIIENKN
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCC
GVASGKIYNIGNPTNNFSVRELAHKMLALAAEFPEYAESAKKVQLVETSSGAYYGAGYQD
CCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHCEEEEEEECCCCEECCCHHH
VQNRVPKIDNTKQELAWAPQSTFDEALRKIFEAYRGHVAEARALVEQQ
HHHCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHCHHHHHHHHHCCC
>Mature Secondary Structure
MKKVLILGVNGFIGHHLSKRILETTDWEVFGMDMQTERLGDLVKHERMHFFEGDITINKE
CCEEEEEECCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHEEECCEEECHH
WVEYHVKKCDVILPLVAIATPATYVQQPLRVFELDFEANLPIVRSAVKYGKHLVFPSTSE
HHHHHHHHHHHHHHHHHHHCCHHHHHCCHHEEEECCCCCCHHHHHHHHHCCEEECCCCHH
VYGMCSDEQFDPDASALTYGPINKPRWIYACSKQLMDRVIWGYGMEGLNFTLFRPFNWIG
HHCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCC
PGLDSIYTPKEGSSRVVTQFLGHIVRGENISLVDGGAQKRAFTDIDDGISALMKIIENKN
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCC
GVASGKIYNIGNPTNNFSVRELAHKMLALAAEFPEYAESAKKVQLVETSSGAYYGAGYQD
CCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHCEEEEEEECCCCEECCCHHH
VQNRVPKIDNTKQELAWAPQSTFDEALRKIFEAYRGHVAEARALVEQQ
HHHCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]