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The map label for this gene is nagZ [H]

Identifier: 186475611

GI number: 186475611

Start: 944619

End: 945650

Strand: Direct

Name: nagZ [H]

Synonym: Bphy_0846

Alternate gene names: 186475611

Gene position: 944619-945650 (Clockwise)

Preceding gene: 186475610

Following gene: 186475616

Centisome position: 27.15

GC content: 65.02

Gene sequence:

>1032_bases
ATGAAACTGACTCCTGGCCCGGTGATGCTCGACGTCGTCGGCAAAGCCCTGAACGCCGATGACGAGCGCCGCCTCGCGCA
CCCAATGACGGGCGGCGTGATCCTGTTTGCACGTCACTTCGAAAGCCGCTCGCAACTGGTCGCGCTGACCGACGCGATTC
GCGCGACTCGCGACGACCTTCTGATCGCCGTCGATCACGAAGGCGGCCGTGTGCAGCGCTTTCGCACCGATGGCTTCACC
GTGCTGCCGTCGATGGGCAAGCTCGGCGCGCTGTGGGACGAGGATGTGCTGCGCGCGACCAAAGTCACGACGGCAGTCGG
CTATGTGCTCGCATCCGAGTTGCGCGCGTGCGGCATCGACATGAGCTTCACGCCCGTGCTCGATTTGAACTACGGTCACT
CGCAGGTGATCGGCGATCGCGCGTTCCATCGCGATCCGCGCGTCGTGACGATGCTGGCGAAGAGCCTGAATCACGGCCTC
GCGCTCGCGGGCATGGCGAACTGCGGGAAGCATTTTCCCGGTCACGGGTTCGCGACGGCGGACTCGCATGTGGCTGTGCC
CGTCGACGAACGTACGCTCGACCAGATTCTCAGCGAAGACGTCGCGCCGTATGACTGGCTCGGACTCTCGCTCGCGTCGG
TGCTGCCGGGGCATGTGATCTATCCGAAGATCGACAGCAAGCCGGCCGGTTTTTCGCGTGTGTGGATCCAGGACATCCTG
CGCAACAAGCTGGGATTCGAGGGCGCGATTTTCAGCGACGATCTGTCGATGGAAGCGGCGCGCCAGGGCGGCACGCTGAC
GGAAGCGGCCACGGCCGCGCTCGAAGCGGGTGTCGACATGGTGCTGATCTGCAATCAGCCCGACGAGGCAGGAAAGGTAC
TGGACGCGCTGCGCGTCACGCAATCGAACGAGTCGAAGCAGCGCCTTGCGCGCATGCGTCCGCGCGGCGACGCGCCGTCA
TGGGCCGCATTGATGGACGAGCCGCAGTATCGACGGGCACAGGCGCTGCTGCGCGAGACTTTCGCTGCGTGA

Upstream 100 bases:

>100_bases
GTGATTGCCGAGACGCCCGATACTGCCGACTGATTCTCCATGCGAGACGGGACGCGCGTCACAGGCGTCGCCGCGCTCTT
TCCTCTACTTCACGAATCCG

Downstream 100 bases:

>100_bases
TCTTCGCGCTGCAGTAGCAATAAGAAAGGACGGGTCTCGATCGAGCCCGTCCTTTTGTTTTGCCGGCAAGCAGCCGATCA
GTTCAGCCGCATCCGTTGCA

Product: beta-hexosaminidase

Products: NA

Alternate protein names: Beta-N-acetylhexosaminidase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MKLTPGPVMLDVVGKALNADDERRLAHPMTGGVILFARHFESRSQLVALTDAIRATRDDLLIAVDHEGGRVQRFRTDGFT
VLPSMGKLGALWDEDVLRATKVTTAVGYVLASELRACGIDMSFTPVLDLNYGHSQVIGDRAFHRDPRVVTMLAKSLNHGL
ALAGMANCGKHFPGHGFATADSHVAVPVDERTLDQILSEDVAPYDWLGLSLASVLPGHVIYPKIDSKPAGFSRVWIQDIL
RNKLGFEGAIFSDDLSMEAARQGGTLTEAATAALEAGVDMVLICNQPDEAGKVLDALRVTQSNESKQRLARMRPRGDAPS
WAALMDEPQYRRAQALLRETFAA

Sequences:

>Translated_343_residues
MKLTPGPVMLDVVGKALNADDERRLAHPMTGGVILFARHFESRSQLVALTDAIRATRDDLLIAVDHEGGRVQRFRTDGFT
VLPSMGKLGALWDEDVLRATKVTTAVGYVLASELRACGIDMSFTPVLDLNYGHSQVIGDRAFHRDPRVVTMLAKSLNHGL
ALAGMANCGKHFPGHGFATADSHVAVPVDERTLDQILSEDVAPYDWLGLSLASVLPGHVIYPKIDSKPAGFSRVWIQDIL
RNKLGFEGAIFSDDLSMEAARQGGTLTEAATAALEAGVDMVLICNQPDEAGKVLDALRVTQSNESKQRLARMRPRGDAPS
WAALMDEPQYRRAQALLRETFAA
>Mature_343_residues
MKLTPGPVMLDVVGKALNADDERRLAHPMTGGVILFARHFESRSQLVALTDAIRATRDDLLIAVDHEGGRVQRFRTDGFT
VLPSMGKLGALWDEDVLRATKVTTAVGYVLASELRACGIDMSFTPVLDLNYGHSQVIGDRAFHRDPRVVTMLAKSLNHGL
ALAGMANCGKHFPGHGFATADSHVAVPVDERTLDQILSEDVAPYDWLGLSLASVLPGHVIYPKIDSKPAGFSRVWIQDIL
RNKLGFEGAIFSDDLSMEAARQGGTLTEAATAALEAGVDMVLICNQPDEAGKVLDALRVTQSNESKQRLARMRPRGDAPS
WAALMDEPQYRRAQALLRETFAA

Specific function: Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides [H]

COG id: COG1472

COG function: function code G; Beta-glucosidase-related glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787350, Length=330, Percent_Identity=43.6363636363636, Blast_Score=250, Evalue=8e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022956
- InterPro:   IPR019800
- InterPro:   IPR001764
- InterPro:   IPR017853 [H]

Pfam domain/function: PF00933 Glyco_hydro_3 [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 37279; Mature: 37279

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTPGPVMLDVVGKALNADDERRLAHPMTGGVILFARHFESRSQLVALTDAIRATRDDL
CCCCCCCCHHHHHHHHHCCCCHHHHHCCCCCCEEEEEEHHCCCHHHHHHHHHHHHCCCCE
LIAVDHEGGRVQRFRTDGFTVLPSMGKLGALWDEDVLRATKVTTAVGYVLASELRACGID
EEEEECCCCEEEEEECCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
MSFTPVLDLNYGHSQVIGDRAFHRDPRVVTMLAKSLNHGLALAGMANCGKHFPGHGFATA
CCCCEEEECCCCCHHHHCCHHHCCCCHHHHHHHHHHCCCEEEEEHHHCCCCCCCCCCCCC
DSHVAVPVDERTLDQILSEDVAPYDWLGLSLASVLPGHVIYPKIDSKPAGFSRVWIQDIL
CCEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHH
RNKLGFEGAIFSDDLSMEAARQGGTLTEAATAALEAGVDMVLICNQPDEAGKVLDALRVT
HHHCCCCCCEECCCCCHHHHHCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHH
QSNESKQRLARMRPRGDAPSWAALMDEPQYRRAQALLRETFAA
CCCHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLTPGPVMLDVVGKALNADDERRLAHPMTGGVILFARHFESRSQLVALTDAIRATRDDL
CCCCCCCCHHHHHHHHHCCCCHHHHHCCCCCCEEEEEEHHCCCHHHHHHHHHHHHCCCCE
LIAVDHEGGRVQRFRTDGFTVLPSMGKLGALWDEDVLRATKVTTAVGYVLASELRACGID
EEEEECCCCEEEEEECCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
MSFTPVLDLNYGHSQVIGDRAFHRDPRVVTMLAKSLNHGLALAGMANCGKHFPGHGFATA
CCCCEEEECCCCCHHHHCCHHHCCCCHHHHHHHHHHCCCEEEEEHHHCCCCCCCCCCCCC
DSHVAVPVDERTLDQILSEDVAPYDWLGLSLASVLPGHVIYPKIDSKPAGFSRVWIQDIL
CCEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHH
RNKLGFEGAIFSDDLSMEAARQGGTLTEAATAALEAGVDMVLICNQPDEAGKVLDALRVT
HHHCCCCCCEECCCCCHHHHHCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHH
QSNESKQRLARMRPRGDAPSWAALMDEPQYRRAQALLRETFAA
CCCHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]