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The map label for this gene is acpS

Identifier: 186475610

GI number: 186475610

Start: 944144

End: 944551

Strand: Direct

Name: acpS

Synonym: Bphy_0845

Alternate gene names: 186475610

Gene position: 944144-944551 (Clockwise)

Preceding gene: 186475609

Following gene: 186475611

Centisome position: 27.14

GC content: 66.67

Gene sequence:

>408_bases
ATGGCGATCTACGGCATCGGCACCGACATCGTTCAGGTCAGCCGCGTCGCGGCAGTGATGCAGCGGACCAACGGGCGCTT
CGCCGAGAAGGTGCTCGGACCCGATGAGTTGCGCGTCTATCACGCGCGCCATGCGCGCTCGCAGGCGCGCGGCCTCGCAT
TTCTCGCGACCCGCTTCTCCGTCAAGGAAGCTTTCTCGAAGGCGATCGGCCTCGGCATGCGCTGGCCGATGACGTGGCGC
GCCTTGCAGACGCTGAACGAGCCGAGCGGACGTCCGACGTGTGTGGCGTCGGGCGAACTCGCCGACTGGCTCGCTGAACG
CGGCATCACGTCGCGCGTGACGCTGTCCGACGAACGCGATTACGCGGTGTCGTTCGTGATTGCCGAGACGCCCGATACTG
CCGACTGA

Upstream 100 bases:

>100_bases
TCTTCGCGGGCTGGGACAACGCCGTGCGCGAGATGAAGGCGATCATGGTCGCCGCGCGTCTTGCGGCGCGCGCATAACCA
GGCAGACAAACGGCACGCGT

Downstream 100 bases:

>100_bases
TTCTCCATGCGAGACGGGACGCGCGTCACAGGCGTCGCCGCGCTCTTTCCTCTACTTCACGAATCCGATGAAACTGACTC
CTGGCCCGGTGATGCTCGAC

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 135; Mature: 134

Protein sequence:

>135_residues
MAIYGIGTDIVQVSRVAAVMQRTNGRFAEKVLGPDELRVYHARHARSQARGLAFLATRFSVKEAFSKAIGLGMRWPMTWR
ALQTLNEPSGRPTCVASGELADWLAERGITSRVTLSDERDYAVSFVIAETPDTAD

Sequences:

>Translated_135_residues
MAIYGIGTDIVQVSRVAAVMQRTNGRFAEKVLGPDELRVYHARHARSQARGLAFLATRFSVKEAFSKAIGLGMRWPMTWR
ALQTLNEPSGRPTCVASGELADWLAERGITSRVTLSDERDYAVSFVIAETPDTAD
>Mature_134_residues
AIYGIGTDIVQVSRVAAVMQRTNGRFAEKVLGPDELRVYHARHARSQARGLAFLATRFSVKEAFSKAIGLGMRWPMTWRA
LQTLNEPSGRPTCVASGELADWLAERGITSRVTLSDERDYAVSFVIAETPDTAD

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=131, Percent_Identity=38.1679389312977, Blast_Score=89, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_BURP8 (B2JFK6)

Other databases:

- EMBL:   CP001043
- RefSeq:   YP_001857080.1
- ProteinModelPortal:   B2JFK6
- SMR:   B2JFK6
- GeneID:   6242343
- GenomeReviews:   CP001043_GR
- KEGG:   bph:Bphy_0845
- HOGENOM:   HBG734479
- OMA:   QGVFWRD
- ProtClustDB:   PRK00070
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 14886; Mature: 14755

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIYGIGTDIVQVSRVAAVMQRTNGRFAEKVLGPDELRVYHARHARSQARGLAFLATRFS
CEEECCCHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHH
VKEAFSKAIGLGMRWPMTWRALQTLNEPSGRPTCVASGELADWLAERGITSRVTLSDERD
HHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCEEEECCHHHHHHHHCCCCEEEEECCCCC
YAVSFVIAETPDTAD
EEEEEEEECCCCCCC
>Mature Secondary Structure 
AIYGIGTDIVQVSRVAAVMQRTNGRFAEKVLGPDELRVYHARHARSQARGLAFLATRFS
EEECCCHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHH
VKEAFSKAIGLGMRWPMTWRALQTLNEPSGRPTCVASGELADWLAERGITSRVTLSDERD
HHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCEEEECCHHHHHHHHCCCCEEEEECCCCC
YAVSFVIAETPDTAD
EEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA