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The map label for this gene is xylB [H]

Identifier: 186475272

GI number: 186475272

Start: 575810

End: 577354

Strand: Direct

Name: xylB [H]

Synonym: Bphy_0504

Alternate gene names: 186475272

Gene position: 575810-577354 (Clockwise)

Preceding gene: 186475271

Following gene: 186475273

Centisome position: 16.55

GC content: 63.24

Gene sequence:

>1545_bases
ATGAATTACGTCATCGGCGTCGATATCGGCACGCAGAGTACGAAGGCCGTGCTCGTCGATCAGAACGGCACCATTGCCGC
GCAGCATTCGAGCAGCTATCACCCGGATACGCCGAAGCCGTTGTGGGCCGAGCAGTGGCCCACCGTGTGGACGAAGGCGG
TCGTCGAATGCATTGCGCGCTGCGTTGCCAAGGCGCGCGAAGCGGGTGTCGCGTCGAACGCGATCAAGGCCGTGTGCGTG
AGCAGCTTGTATGGCGGCTCGGGCATCCCCGTCGACAGCGACATGAAGCCACTGTATCCGTGTCTGATCTGGATGGACCG
GCGCGCGACCGCGCAGGTCGAATGGGTCCGCGAAAACGTCGATCTCGACCGTCTGTATGCGATCACGGGCAATAGCGTCG
ACAGCTACTACGGCTATACGAAGATGCTGTGGCTGCGCGACAACGAGCCGAACGTGTGGGCGAACACGCGCTTCTTCCTG
CCGCCCAACGCGTACGTGATCTATCTGCTGACGGGCGAAGTCGCTGTCGATCACAGTTCGGCGGGCAACATCGGCGGCGT
GTACGACATCGCGAAGCGCGACTGGTCCGACGAAGCGCTCGACATGCTCGGCATTCCCGCAACGATGATGCCGGAGCATC
TCGTCGAATCGTCGGATGTCGTGGGCGGCTTGCTGTCGCAATGGACGGAGCAGCTGGGTCTCGAAGCGGGCACGCCGATC
GTCGCGGGCGGCGTCGACGCTGCAATGGCCACCTATGCGGCCGGCGTCACGCGCGCGGGCCAACATGTCGCGATGATCGG
CACGAGCATGTGCTGGGGCTACATCAATCAGAGCGTCGATGCGCGGCATGGACTGGTCAGCATGCCGCATGTGTTCAACG
GGCTGCGGGACATTTACGTGTTTGGCGGCGCGATTACGGCGGGGGCATCGGTGACGTGGTACCGCGAGCAGTTCTGCCAC
GCCGAGATCGAAGCCGCCAAGGCGATACCCGACGGCGATGCGCATCAGTTACTCGAAGAAGACGCGGCGCAGATTCCGGC
CGGTGCAGATGGCGTCATGTTCTTGCCGTATCTGATGGGGGAGCGCAGCCCCGTGTGGGACGCGAAGGCTAGTGGTGCGT
TCGTCGGTCTGAACCTGTATCACACGCGGGCGCATCTGTATCGGGCGGTGCTCGAGGGCGTCGCGTTCGCGCTGCAGCAC
AACATCGTCGCGGGGCGCAAGGGAGCGAAGTCGCTGGACGACAAGCTGATCGTCGTCGGCGGCGCGGCGCATTCGGACCT
GTGGATGTCGATCATCGCGGATATCACGGGTTTCCCTGTGTACACGATCGAACAGGAGGTCGAAGCGGCGATGGGCGCGG
CGTTGCTCGCGGCATATGGCACCAGGCTGATTTCGCAAGAGACCGCGCGTGGCGGCTGGGTGAAGCTGATCGAGCGCGTG
AAGCCCGATGCGGCGCGACAGGCGATGTACGCGGAGCGCTTCGGCATTTATACGGAACTGTATCCGGCGTTGAAGCCGGT
CATGCATCGACTGCAAGCAAAATGA

Upstream 100 bases:

>100_bases
CGATCAAGGTGTTGTTGAAGCCTGCCCGCTAGCTGGATAGTTCGTCCGTCATTCGAAAAATGCACAGTGCGCGTCGTGCA
GACGCGCACACGGAGACACT

Downstream 100 bases:

>100_bases
ACATGACCTTTGATTTTTCCGGTCGCTCGATACTCGTGACGGGCGCATCGAGCGGCATCGGCCGCACCACGGTCGAGCTG
TTGTGCGCAAGCGGCGCGCA

Product: xylulokinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MNYVIGVDIGTQSTKAVLVDQNGTIAAQHSSSYHPDTPKPLWAEQWPTVWTKAVVECIARCVAKAREAGVASNAIKAVCV
SSLYGGSGIPVDSDMKPLYPCLIWMDRRATAQVEWVRENVDLDRLYAITGNSVDSYYGYTKMLWLRDNEPNVWANTRFFL
PPNAYVIYLLTGEVAVDHSSAGNIGGVYDIAKRDWSDEALDMLGIPATMMPEHLVESSDVVGGLLSQWTEQLGLEAGTPI
VAGGVDAAMATYAAGVTRAGQHVAMIGTSMCWGYINQSVDARHGLVSMPHVFNGLRDIYVFGGAITAGASVTWYREQFCH
AEIEAAKAIPDGDAHQLLEEDAAQIPAGADGVMFLPYLMGERSPVWDAKASGAFVGLNLYHTRAHLYRAVLEGVAFALQH
NIVAGRKGAKSLDDKLIVVGGAAHSDLWMSIIADITGFPVYTIEQEVEAAMGAALLAAYGTRLISQETARGGWVKLIERV
KPDAARQAMYAERFGIYTELYPALKPVMHRLQAK

Sequences:

>Translated_514_residues
MNYVIGVDIGTQSTKAVLVDQNGTIAAQHSSSYHPDTPKPLWAEQWPTVWTKAVVECIARCVAKAREAGVASNAIKAVCV
SSLYGGSGIPVDSDMKPLYPCLIWMDRRATAQVEWVRENVDLDRLYAITGNSVDSYYGYTKMLWLRDNEPNVWANTRFFL
PPNAYVIYLLTGEVAVDHSSAGNIGGVYDIAKRDWSDEALDMLGIPATMMPEHLVESSDVVGGLLSQWTEQLGLEAGTPI
VAGGVDAAMATYAAGVTRAGQHVAMIGTSMCWGYINQSVDARHGLVSMPHVFNGLRDIYVFGGAITAGASVTWYREQFCH
AEIEAAKAIPDGDAHQLLEEDAAQIPAGADGVMFLPYLMGERSPVWDAKASGAFVGLNLYHTRAHLYRAVLEGVAFALQH
NIVAGRKGAKSLDDKLIVVGGAAHSDLWMSIIADITGFPVYTIEQEVEAAMGAALLAAYGTRLISQETARGGWVKLIERV
KPDAARQAMYAERFGIYTELYPALKPVMHRLQAK
>Mature_514_residues
MNYVIGVDIGTQSTKAVLVDQNGTIAAQHSSSYHPDTPKPLWAEQWPTVWTKAVVECIARCVAKAREAGVASNAIKAVCV
SSLYGGSGIPVDSDMKPLYPCLIWMDRRATAQVEWVRENVDLDRLYAITGNSVDSYYGYTKMLWLRDNEPNVWANTRFFL
PPNAYVIYLLTGEVAVDHSSAGNIGGVYDIAKRDWSDEALDMLGIPATMMPEHLVESSDVVGGLLSQWTEQLGLEAGTPI
VAGGVDAAMATYAAGVTRAGQHVAMIGTSMCWGYINQSVDARHGLVSMPHVFNGLRDIYVFGGAITAGASVTWYREQFCH
AEIEAAKAIPDGDAHQLLEEDAAQIPAGADGVMFLPYLMGERSPVWDAKASGAFVGLNLYHTRAHLYRAVLEGVAFALQH
NIVAGRKGAKSLDDKLIVVGGAAHSDLWMSIIADITGFPVYTIEQEVEAAMGAALLAAYGTRLISQETARGGWVKLIERV
KPDAARQAMYAERFGIYTELYPALKPVMHRLQAK

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI41393575, Length=449, Percent_Identity=26.5033407572383, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI42794763, Length=453, Percent_Identity=24.9448123620309, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI4504007, Length=453, Percent_Identity=25.3863134657837, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI189409120, Length=453, Percent_Identity=25.3863134657837, Blast_Score=119, Evalue=7e-27,
Organism=Escherichia coli, GI1789987, Length=512, Percent_Identity=29.8828125, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1787789, Length=516, Percent_Identity=27.3255813953488, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI1789168, Length=519, Percent_Identity=26.7822736030828, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1790005, Length=522, Percent_Identity=26.2452107279693, Blast_Score=149, Evalue=5e-37,
Organism=Escherichia coli, GI1790361, Length=471, Percent_Identity=26.5392781316348, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1789138, Length=516, Percent_Identity=24.6124031007752, Blast_Score=94, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17535599, Length=462, Percent_Identity=25.3246753246753, Blast_Score=114, Evalue=8e-26,
Organism=Drosophila melanogaster, GI17864214, Length=478, Percent_Identity=25.9414225941423, Blast_Score=122, Evalue=8e-28,
Organism=Drosophila melanogaster, GI24655555, Length=432, Percent_Identity=24.0740740740741, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24655560, Length=432, Percent_Identity=24.0740740740741, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24655570, Length=432, Percent_Identity=24.0740740740741, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24655574, Length=432, Percent_Identity=24.0740740740741, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24655565, Length=432, Percent_Identity=24.0740740740741, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24654573, Length=427, Percent_Identity=25.9953161592506, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24657106, Length=553, Percent_Identity=23.869801084991, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24657102, Length=553, Percent_Identity=23.869801084991, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 55773; Mature: 55773

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYVIGVDIGTQSTKAVLVDQNGTIAAQHSSSYHPDTPKPLWAEQWPTVWTKAVVECIAR
CCEEEEEEECCCCCEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
CVAKAREAGVASNAIKAVCVSSLYGGSGIPVDSDMKPLYPCLIWMDRRATAQVEWVRENV
HHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHEEECCCCCHHHHHHHHCC
DLDRLYAITGNSVDSYYGYTKMLWLRDNEPNVWANTRFFLPPNAYVIYLLTGEVAVDHSS
CHHHEEEEECCCCHHHCCCEEEEEEECCCCCEEECEEEEECCCCEEEEEEECCEEEECCC
AGNIGGVYDIAKRDWSDEALDMLGIPATMMPEHLVESSDVVGGLLSQWTEQLGLEAGTPI
CCCCCCCHHHHHCCCCHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCE
VAGGVDAAMATYAAGVTRAGQHVAMIGTSMCWGYINQSVDARHGLVSMPHVFNGLRDIYV
EECCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCCHHHCCCEECHHHHHHHHHHEE
FGGAITAGASVTWYREQFCHAEIEAAKAIPDGDAHQLLEEDAAQIPAGADGVMFLPYLMG
ECCHHHCCCEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCEEHHHHHC
ERSPVWDAKASGAFVGLNLYHTRAHLYRAVLEGVAFALQHNIVAGRKGAKSLDDKLIVVG
CCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEE
GAAHSDLWMSIIADITGFPVYTIEQEVEAAMGAALLAAYGTRLISQETARGGWVKLIERV
CCCCHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
KPDAARQAMYAERFGIYTELYPALKPVMHRLQAK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNYVIGVDIGTQSTKAVLVDQNGTIAAQHSSSYHPDTPKPLWAEQWPTVWTKAVVECIAR
CCEEEEEEECCCCCEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
CVAKAREAGVASNAIKAVCVSSLYGGSGIPVDSDMKPLYPCLIWMDRRATAQVEWVRENV
HHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHEEECCCCCHHHHHHHHCC
DLDRLYAITGNSVDSYYGYTKMLWLRDNEPNVWANTRFFLPPNAYVIYLLTGEVAVDHSS
CHHHEEEEECCCCHHHCCCEEEEEEECCCCCEEECEEEEECCCCEEEEEEECCEEEECCC
AGNIGGVYDIAKRDWSDEALDMLGIPATMMPEHLVESSDVVGGLLSQWTEQLGLEAGTPI
CCCCCCCHHHHHCCCCHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCE
VAGGVDAAMATYAAGVTRAGQHVAMIGTSMCWGYINQSVDARHGLVSMPHVFNGLRDIYV
EECCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCCHHHCCCEECHHHHHHHHHHEE
FGGAITAGASVTWYREQFCHAEIEAAKAIPDGDAHQLLEEDAAQIPAGADGVMFLPYLMG
ECCHHHCCCEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCEEHHHHHC
ERSPVWDAKASGAFVGLNLYHTRAHLYRAVLEGVAFALQHNIVAGRKGAKSLDDKLIVVG
CCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEE
GAAHSDLWMSIIADITGFPVYTIEQEVEAAMGAALLAAYGTRLISQETARGGWVKLIERV
CCCCHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
KPDAARQAMYAERFGIYTELYPALKPVMHRLQAK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 2994009 [H]