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The map label for this gene is hcrA [H]

Identifier: 183222725

GI number: 183222725

Start: 3500627

End: 3501667

Strand: Reverse

Name: hcrA [H]

Synonym: LEPBI_I3381

Alternate gene names: 183222725

Gene position: 3501667-3500627 (Counterclockwise)

Preceding gene: 183222726

Following gene: 183222724

Centisome position: 97.28

GC content: 41.79

Gene sequence:

>1041_bases
TTGGAGGCTATGGACCTTTCCCCTAGACATCGTTCCATTTTGAAAGCATTGGTTGAGGAGTTTGTTTCAGACAACAAACC
TGTCGGCTCCAAAACCCTTTCTGAAAAATACGATATCGGCCTTTCACCAGCTACCATTCGTTCCTGCCTTGCGGAACTAG
AGGACATGGGTTTCATTGTGGCCCGACATACCTCTGGGGGCCGTGTGCCAACGGAACGAGGGTATCGGTTGTATGTGGAT
AGCCTTGTGACTCTATTTGAGCTCACGATGCGTGAGAAACAAAGGATCCAGGAAGAGTATCTTCGGATGCAATTTCGATT
GGACCAAGTTCTCATCGCAACCTCCAAGGTATTAGCTTCTCTTTCGCAATCAGCGAGTGTGGTTCTTGGTCCGGAAGGAT
CTTTGGATACACTCAAACACATTGAACTCATCCATGTCAATGGTGGAGAAGTTCTGATGATCCTTGTGATGCGGTCAGGT
ACTGTGCTGAATCGAAATATCTTTTTCGATTTTCATATCTCACAGGAGACCTTGTACCAAATTTCAAGGTATTTGAATGA
TAACGTCAAAGGTTTTGATGTTCATGAAATTCAAAGTAATCTGATCCCTCAGATGATGTTGAAAAAGGAAGGTCCAGAAG
GATTCACTTTGTTCGCACCTTCTATTGCAAGGGCTATGGGAACAGATAGTCATTCTGTTGATAACTTGTATATCGATGGA
TTGAAAAACTTATACGAAAACTTTAAGGATGAAGAGGAGCAATTAGAAAACATCCTGCATCTATTTGATGAAAAACAGTT
CCTCAAAGAATTTTTTAGCGATTATGTTCCGATGGATGGTGTATACACGATTATCGGAAAAGACGGCAATGAGAAGTTAG
GTGGTGTTACCATCATCACAACCAATTACCGTATGGGTGAAAAGAGGATTGGTTCCATGGGAATCATAGGTCCTCAGAGG
ATGAATTACAACAAAGCATTACCTTTGATTGAGTTCACTTCAAAGTTAGTTTCAGAAATGATAACGAAATTGAGCAGGTA
G

Upstream 100 bases:

>100_bases
TCGCCCCTTGGATCAGCATCTTGCTTGACGAAAAAAATGGGAATTCGTAAACTTTAAGCATAGATTAGCACTCTAATCAT
CAGAGTGCTAAAGGAAGAGC

Downstream 100 bases:

>100_bases
TAGGAGGCGAAATGGCAGAAGAAACGAACCAATCCCTAGAAGATCAAAATGTGCAAGTCGAAGAAGGGCAGACCATTTCA
GATGAGGCCATTGAACAAGC

Product: heat-inducible transcription repressor HrcA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MEAMDLSPRHRSILKALVEEFVSDNKPVGSKTLSEKYDIGLSPATIRSCLAELEDMGFIVARHTSGGRVPTERGYRLYVD
SLVTLFELTMREKQRIQEEYLRMQFRLDQVLIATSKVLASLSQSASVVLGPEGSLDTLKHIELIHVNGGEVLMILVMRSG
TVLNRNIFFDFHISQETLYQISRYLNDNVKGFDVHEIQSNLIPQMMLKKEGPEGFTLFAPSIARAMGTDSHSVDNLYIDG
LKNLYENFKDEEEQLENILHLFDEKQFLKEFFSDYVPMDGVYTIIGKDGNEKLGGVTIITTNYRMGEKRIGSMGIIGPQR
MNYNKALPLIEFTSKLVSEMITKLSR

Sequences:

>Translated_346_residues
MEAMDLSPRHRSILKALVEEFVSDNKPVGSKTLSEKYDIGLSPATIRSCLAELEDMGFIVARHTSGGRVPTERGYRLYVD
SLVTLFELTMREKQRIQEEYLRMQFRLDQVLIATSKVLASLSQSASVVLGPEGSLDTLKHIELIHVNGGEVLMILVMRSG
TVLNRNIFFDFHISQETLYQISRYLNDNVKGFDVHEIQSNLIPQMMLKKEGPEGFTLFAPSIARAMGTDSHSVDNLYIDG
LKNLYENFKDEEEQLENILHLFDEKQFLKEFFSDYVPMDGVYTIIGKDGNEKLGGVTIITTNYRMGEKRIGSMGIIGPQR
MNYNKALPLIEFTSKLVSEMITKLSR
>Mature_346_residues
MEAMDLSPRHRSILKALVEEFVSDNKPVGSKTLSEKYDIGLSPATIRSCLAELEDMGFIVARHTSGGRVPTERGYRLYVD
SLVTLFELTMREKQRIQEEYLRMQFRLDQVLIATSKVLASLSQSASVVLGPEGSLDTLKHIELIHVNGGEVLMILVMRSG
TVLNRNIFFDFHISQETLYQISRYLNDNVKGFDVHEIQSNLIPQMMLKKEGPEGFTLFAPSIARAMGTDSHSVDNLYIDG
LKNLYENFKDEEEQLENILHLFDEKQFLKEFFSDYVPMDGVYTIIGKDGNEKLGGVTIITTNYRMGEKRIGSMGIIGPQR
MNYNKALPLIEFTSKLVSEMITKLSR

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 39264; Mature: 39264

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAMDLSPRHRSILKALVEEFVSDNKPVGSKTLSEKYDIGLSPATIRSCLAELEDMGFIV
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCEEE
ARHTSGGRVPTERGYRLYVDSLVTLFELTMREKQRIQEEYLRMQFRLDQVLIATSKVLAS
EEECCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSQSASVVLGPEGSLDTLKHIELIHVNGGEVLMILVMRSGTVLNRNIFFDFHISQETLYQ
HHCCCEEEECCCCCCCHHHCEEEEEECCCCEEEEEEECCCCEEECEEEEEEECCHHHHHH
ISRYLNDNVKGFDVHEIQSNLIPQMMLKKEGPEGFTLFAPSIARAMGTDSHSVDNLYIDG
HHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHCCCCCCCCHHHHHH
LKNLYENFKDEEEQLENILHLFDEKQFLKEFFSDYVPMDGVYTIIGKDGNEKLGGVTIIT
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEEEE
TNYRMGEKRIGSMGIIGPQRMNYNKALPLIEFTSKLVSEMITKLSR
ECCCCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEAMDLSPRHRSILKALVEEFVSDNKPVGSKTLSEKYDIGLSPATIRSCLAELEDMGFIV
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCEEE
ARHTSGGRVPTERGYRLYVDSLVTLFELTMREKQRIQEEYLRMQFRLDQVLIATSKVLAS
EEECCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSQSASVVLGPEGSLDTLKHIELIHVNGGEVLMILVMRSGTVLNRNIFFDFHISQETLYQ
HHCCCEEEECCCCCCCHHHCEEEEEECCCCEEEEEEECCCCEEECEEEEEEECCHHHHHH
ISRYLNDNVKGFDVHEIQSNLIPQMMLKKEGPEGFTLFAPSIARAMGTDSHSVDNLYIDG
HHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHCCCCCCCCHHHHHH
LKNLYENFKDEEEQLENILHLFDEKQFLKEFFSDYVPMDGVYTIIGKDGNEKLGGVTIIT
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEEEE
TNYRMGEKRIGSMGIIGPQRMNYNKALPLIEFTSKLVSEMITKLSR
ECCCCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA