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The map label for this gene is ctaC [H]

Identifier: 183222042

GI number: 183222042

Start: 2781304

End: 2782266

Strand: Reverse

Name: ctaC [H]

Synonym: LEPBI_I2684

Alternate gene names: 183222042

Gene position: 2782266-2781304 (Counterclockwise)

Preceding gene: 183222043

Following gene: 183222041

Centisome position: 77.29

GC content: 42.58

Gene sequence:

>963_bases
ATGTCTTGGAGCAGTCTCATTCCAGCGACCTCGTTCATGCCTATCCAGGCCACTGAAATCGCAAAAGAAGTCGATCTTCT
CTATGCATTTCTGATCATCGCAAGCCTTGTTTCGTTTGTCATCTTGATTGGTGGAATGACATGGTTCCTCATCAAGTTCA
AACGTACAAGTGTAGACCAGAAATCCGCATACATTACTCACAATAATTTTGCAGAGTTCCTTTGGTCCTTTATCCCTCTC
GTCATCATGATGGGAATTTTCTATTGGGGTATGGTTATTTTTGAAAAACTGAGAACCCCACCAGAAGACGTGGCGGCAGA
AATTCATGTCACTGCAGAACAGTGGGCATGGACGTACCGTTATGCGAATGGAAAAGAGTTCTATAGTTCAGCAAATGATC
CAATGATTGTTCCTGCTGGAAAAGCAACGAAACTCATTCTCACTTCGAAAGACGTCATCCATAGTTTTTATGTTCCGGCT
TTCCGAACCAAACAAGATGCGGTTCCAGGAAAACTCACTCAACTTTGGTTTGAGCCAAAACAACCAGGAGAATACATCGT
TTTTTGTACAGAATATTGCGGAACCAAACACTCCGGAATGATGATCAAAATCAAAGCGATCCCTTCTGAAGAATATGCGG
CTTGGTACCATGCTGAGAAAAAAGGTGCGGACTCTCCTGCTGACTTAGGGAAAGTTTTGTTTGCCCAAAAAGCTTGCGCT
TCTTGTCACTCCATTGATGGATCCCGAGTTGTTGGACCAACAATGAAAGGTCTTTTTGGATCGGAGCGTAAGTTTGCTGA
TGGAACCAAAGCTAAGGCGGATGAAAATTACCTTCGCGAATCCATCTTGGTATCTTCTGCAAAAATTGTAGAAACTTACC
CAGCAGCCATGCCGTTATTCCAAGGCCAATTGTCTGATGAAGACGTTGCCAACTTAATTGAATATATCAAATCCATTAAA
TAA

Upstream 100 bases:

>100_bases
GATGCAATTCGGGGGGGCGGTCACCTTACTCCTTCTCGGTGCGTTTTTATACATAAACTGGCGAAAAATAACAAATAACA
ACCGTCAAGGAGTCACATAG

Downstream 100 bases:

>100_bases
GGAAGAGAGATGAGTTCAGCACATACAAAAACCGAACATGGTCACACAGACCATAATTACCTGAACCACGGATCTGGAAT
CTGGTCTTGGATGACCACTC

Product: cytochrome c oxidase polypeptide II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II; Oxidase aa(3) subunit 2 [H]

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MSWSSLIPATSFMPIQATEIAKEVDLLYAFLIIASLVSFVILIGGMTWFLIKFKRTSVDQKSAYITHNNFAEFLWSFIPL
VIMMGIFYWGMVIFEKLRTPPEDVAAEIHVTAEQWAWTYRYANGKEFYSSANDPMIVPAGKATKLILTSKDVIHSFYVPA
FRTKQDAVPGKLTQLWFEPKQPGEYIVFCTEYCGTKHSGMMIKIKAIPSEEYAAWYHAEKKGADSPADLGKVLFAQKACA
SCHSIDGSRVVGPTMKGLFGSERKFADGTKAKADENYLRESILVSSAKIVETYPAAMPLFQGQLSDEDVANLIEYIKSIK

Sequences:

>Translated_320_residues
MSWSSLIPATSFMPIQATEIAKEVDLLYAFLIIASLVSFVILIGGMTWFLIKFKRTSVDQKSAYITHNNFAEFLWSFIPL
VIMMGIFYWGMVIFEKLRTPPEDVAAEIHVTAEQWAWTYRYANGKEFYSSANDPMIVPAGKATKLILTSKDVIHSFYVPA
FRTKQDAVPGKLTQLWFEPKQPGEYIVFCTEYCGTKHSGMMIKIKAIPSEEYAAWYHAEKKGADSPADLGKVLFAQKACA
SCHSIDGSRVVGPTMKGLFGSERKFADGTKAKADENYLRESILVSSAKIVETYPAAMPLFQGQLSDEDVANLIEYIKSIK
>Mature_319_residues
SWSSLIPATSFMPIQATEIAKEVDLLYAFLIIASLVSFVILIGGMTWFLIKFKRTSVDQKSAYITHNNFAEFLWSFIPLV
IMMGIFYWGMVIFEKLRTPPEDVAAEIHVTAEQWAWTYRYANGKEFYSSANDPMIVPAGKATKLILTSKDVIHSFYVPAF
RTKQDAVPGKLTQLWFEPKQPGEYIVFCTEYCGTKHSGMMIKIKAIPSEEYAAWYHAEKKGADSPADLGKVLFAQKACAS
CHSIDGSRVVGPTMKGLFGSERKFADGTKAKADENYLRESILVSSAKIVETYPAAMPLFQGQLSDEDVANLIEYIKSIK

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=155, Percent_Identity=29.6774193548387, Blast_Score=80, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6226540, Length=221, Percent_Identity=25.3393665158371, Blast_Score=87, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR009056
- InterPro:   IPR003088
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM; PF00034 Cytochrom_C [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 35860; Mature: 35729

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA ; PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWSSLIPATSFMPIQATEIAKEVDLLYAFLIIASLVSFVILIGGMTWFLIKFKRTSVDQ
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEEHHHCCCCC
KSAYITHNNFAEFLWSFIPLVIMMGIFYWGMVIFEKLRTPPEDVAAEIHVTAEQWAWTYR
CCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEEEEEHHHHEEEEE
YANGKEFYSSANDPMIVPAGKATKLILTSKDVIHSFYVPAFRTKQDAVPGKLTQLWFEPK
ECCCHHHHCCCCCCEEEECCCCEEEEEECHHHHHHHHCCCCCCCCCCCCCHHHHHEECCC
QPGEYIVFCTEYCGTKHSGMMIKIKAIPSEEYAAWYHAEKKGADSPADLGKVLFAQKACA
CCCCEEEEEEHHCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
SCHSIDGSRVVGPTMKGLFGSERKFADGTKAKADENYLRESILVSSAKIVETYPAAMPLF
HHHCCCCCEEECCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHH
QGQLSDEDVANLIEYIKSIK
CCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SWSSLIPATSFMPIQATEIAKEVDLLYAFLIIASLVSFVILIGGMTWFLIKFKRTSVDQ
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEEHHHCCCCC
KSAYITHNNFAEFLWSFIPLVIMMGIFYWGMVIFEKLRTPPEDVAAEIHVTAEQWAWTYR
CCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEEEEEHHHHEEEEE
YANGKEFYSSANDPMIVPAGKATKLILTSKDVIHSFYVPAFRTKQDAVPGKLTQLWFEPK
ECCCHHHHCCCCCCEEEECCCCEEEEEECHHHHHHHHCCCCCCCCCCCCCHHHHHEECCC
QPGEYIVFCTEYCGTKHSGMMIKIKAIPSEEYAAWYHAEKKGADSPADLGKVLFAQKACA
CCCCEEEEEEHHCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
SCHSIDGSRVVGPTMKGLFGSERKFADGTKAKADENYLRESILVSSAKIVETYPAAMPLF
HHHCCCCCEEECCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHH
QGQLSDEDVANLIEYIKSIK
CCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7678007 [H]