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The map label for this gene is adrA [H]

Identifier: 183221987

GI number: 183221987

Start: 2720913

End: 2722133

Strand: Direct

Name: adrA [H]

Synonym: LEPBI_I2628

Alternate gene names: 183221987

Gene position: 2720913-2722133 (Clockwise)

Preceding gene: 183221986

Following gene: 183221989

Centisome position: 75.59

GC content: 38.57

Gene sequence:

>1221_bases
GTGCAAGTGAAATCGGCGATGACCAAATCTCATACTTCTCCAAGGCCTGTGCATGGCAAACGCATTGAAGATACCATCAT
GGATCTTTTAGAAGAAGATCCGAACCAGGAAAGCCAACTCATCTCAAAATTAGAATTGAGCCATCCTCATCTCAAAGATA
GATCACTTCTGTATTCGACAGTTCTGAAAGTACTCACCTCTCTTGAATTGATCGAATCTGAGGCGATGGACGTTTGGCAT
GCAGTTTTAGAGAACCAAACCAAACTCTCCGAATGTTTAAAAAGACCTGTCGGATTTCGTGTTGCCTTATTAGATTTTTT
TACAAACCAAAACCAAAAAATCAAAAACCCTAAAATCATAGAACTTCGATTGTATTCAGAAACGGAAAAACTGATCTTAG
TGGATGAACTCACAAGGCTTTACAATCGTCGGCATTTTGAAACTGCTCTTCTTCGTGAATTCAAACAATCCACTCGTTAC
AACCTAAACCTTTCGCTCCTTATCATTGATATTGATGATTTCAAAAAAATCAATGATACCTATGGACATTTGATGGGTGA
TGAAATCTTAAAACAAATTGCTAGTAAAATCTCTACCAGTTTACGAATGGAAGATACTGCGTGTCGTATTGGTGGGGAAG
AATTTGCCATCATCTTCCCACAATCAAACGAATCACAAGCTCTCAAAGCCGCCGAAAAATTATTAGAAGCATGTCGCACG
ATTCAAATTAGTGGGAAACCTGTCACGATCAGTGGAGGACTTGTCTCCTATCCTGAAAAGGTAAAACGTTGCGAAGATAT
GTATGATTTAGCCGATCGAGCCTTGTACACTGCAAAAGACACAGGCAAAAATCAAATCATCGTGTATTCCAATGAAAAAC
GAAGTAGTCTCCGATTTGAAACCAATTTGGAATTGTTTTGTGTCCTACCAAATAAAACCATTCGATCGATTTCCAAAAAT
ATATCCATCACTGGCATTGCCTTCGAAACGGAAGATGATTTATCTTTGAACGATTCCATTCCTGTTTTACTACGCGAATC
AGACTCGAATCACGAAATCAATGCGAAGATCAAAGTGGTGAGAAAACAAAAAATTGGTGAAAAGAGTTATAGTGTAGGAG
CGGAATTCGTGGAACTTTCCAACGAATCCCAAACCAAACTAGCTGATTTATATCTACTACACCAATTTAAAGCAAAGAGC
CCAATGGGTGCAGTAGTTTAA

Upstream 100 bases:

>100_bases
ATTAGGGATTTAGATGAAACTGAATTTGGTTCTTCCCTAAAACCTGTCTTTACAAGAGTCTCTGCTGATAGATTTTTGGG
ATATTGGCAATTTATTTCAA

Downstream 100 bases:

>100_bases
ACTAAAAAAGATAAGTTCGCTTAACGAGAATTAGGCATATCTCCTAAACCACCAGCATTGATGACAGAAGAGTAACCACT
CGCAGTCAAAATTTGTTTTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MQVKSAMTKSHTSPRPVHGKRIEDTIMDLLEEDPNQESQLISKLELSHPHLKDRSLLYSTVLKVLTSLELIESEAMDVWH
AVLENQTKLSECLKRPVGFRVALLDFFTNQNQKIKNPKIIELRLYSETEKLILVDELTRLYNRRHFETALLREFKQSTRY
NLNLSLLIIDIDDFKKINDTYGHLMGDEILKQIASKISTSLRMEDTACRIGGEEFAIIFPQSNESQALKAAEKLLEACRT
IQISGKPVTISGGLVSYPEKVKRCEDMYDLADRALYTAKDTGKNQIIVYSNEKRSSLRFETNLELFCVLPNKTIRSISKN
ISITGIAFETEDDLSLNDSIPVLLRESDSNHEINAKIKVVRKQKIGEKSYSVGAEFVELSNESQTKLADLYLLHQFKAKS
PMGAVV

Sequences:

>Translated_406_residues
MQVKSAMTKSHTSPRPVHGKRIEDTIMDLLEEDPNQESQLISKLELSHPHLKDRSLLYSTVLKVLTSLELIESEAMDVWH
AVLENQTKLSECLKRPVGFRVALLDFFTNQNQKIKNPKIIELRLYSETEKLILVDELTRLYNRRHFETALLREFKQSTRY
NLNLSLLIIDIDDFKKINDTYGHLMGDEILKQIASKISTSLRMEDTACRIGGEEFAIIFPQSNESQALKAAEKLLEACRT
IQISGKPVTISGGLVSYPEKVKRCEDMYDLADRALYTAKDTGKNQIIVYSNEKRSSLRFETNLELFCVLPNKTIRSISKN
ISITGIAFETEDDLSLNDSIPVLLRESDSNHEINAKIKVVRKQKIGEKSYSVGAEFVELSNESQTKLADLYLLHQFKAKS
PMGAVV
>Mature_406_residues
MQVKSAMTKSHTSPRPVHGKRIEDTIMDLLEEDPNQESQLISKLELSHPHLKDRSLLYSTVLKVLTSLELIESEAMDVWH
AVLENQTKLSECLKRPVGFRVALLDFFTNQNQKIKNPKIIELRLYSETEKLILVDELTRLYNRRHFETALLREFKQSTRY
NLNLSLLIIDIDDFKKINDTYGHLMGDEILKQIASKISTSLRMEDTACRIGGEEFAIIFPQSNESQALKAAEKLLEACRT
IQISGKPVTISGGLVSYPEKVKRCEDMYDLADRALYTAKDTGKNQIIVYSNEKRSSLRFETNLELFCVLPNKTIRSISKN
ISITGIAFETEDDLSLNDSIPVLLRESDSNHEINAKIKVVRKQKIGEKSYSVGAEFVELSNESQTKLADLYLLHQFKAKS
PMGAVV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=154, Percent_Identity=38.3116883116883, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI145693134, Length=164, Percent_Identity=35.3658536585366, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1787262, Length=164, Percent_Identity=36.5853658536585, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI87082007, Length=170, Percent_Identity=38.8235294117647, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI87081881, Length=171, Percent_Identity=35.672514619883, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787816, Length=159, Percent_Identity=33.3333333333333, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1788381, Length=166, Percent_Identity=28.9156626506024, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1788085, Length=172, Percent_Identity=31.9767441860465, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787541, Length=176, Percent_Identity=28.9772727272727, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87081974, Length=198, Percent_Identity=29.2929292929293, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1787802, Length=160, Percent_Identity=30.625, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1787056, Length=165, Percent_Identity=29.6969696969697, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1788956, Length=219, Percent_Identity=29.6803652968037, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR007894 [H]

Pfam domain/function: PF00990 GGDEF; PF05230 MASE2 [H]

EC number: NA

Molecular weight: Translated: 46227; Mature: 46227

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVKSAMTKSHTSPRPVHGKRIEDTIMDLLEEDPNQESQLISKLELSHPHLKDRSLLYST
CCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHH
VLKVLTSLELIESEAMDVWHAVLENQTKLSECLKRPVGFRVALLDFFTNQNQKIKNPKII
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEHHHHHHCCCCCCCCCCCEE
ELRLYSETEKLILVDELTRLYNRRHFETALLREFKQSTRYNLNLSLLIIDIDDFKKINDT
EEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECHHHHHHHHH
YGHLMGDEILKQIASKISTSLRMEDTACRIGGEEFAIIFPQSNESQALKAAEKLLEACRT
HHHHHHHHHHHHHHHHHHHHHEECHHHHEECCCEEEEEECCCCCHHHHHHHHHHHHHHHE
IQISGKPVTISGGLVSYPEKVKRCEDMYDLADRALYTAKDTGKNQIIVYSNEKRSSLRFE
EEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCCEEEEEECCCCCCEEEE
TNLELFCVLPNKTIRSISKNISITGIAFETEDDLSLNDSIPVLLRESDSNHEINAKIKVV
CCCEEEEECCCHHHHHHHCCCEEEEEEEECCCCCCCCCCCCEEEEECCCCCEECEEEEEE
RKQKIGEKSYSVGAEFVELSNESQTKLADLYLLHQFKAKSPMGAVV
EHHHCCCHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MQVKSAMTKSHTSPRPVHGKRIEDTIMDLLEEDPNQESQLISKLELSHPHLKDRSLLYST
CCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHH
VLKVLTSLELIESEAMDVWHAVLENQTKLSECLKRPVGFRVALLDFFTNQNQKIKNPKII
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEHHHHHHCCCCCCCCCCCEE
ELRLYSETEKLILVDELTRLYNRRHFETALLREFKQSTRYNLNLSLLIIDIDDFKKINDT
EEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECHHHHHHHHH
YGHLMGDEILKQIASKISTSLRMEDTACRIGGEEFAIIFPQSNESQALKAAEKLLEACRT
HHHHHHHHHHHHHHHHHHHHHEECHHHHEECCCEEEEEECCCCCHHHHHHHHHHHHHHHE
IQISGKPVTISGGLVSYPEKVKRCEDMYDLADRALYTAKDTGKNQIIVYSNEKRSSLRFE
EEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCCEEEEEECCCCCCEEEE
TNLELFCVLPNKTIRSISKNISITGIAFETEDDLSLNDSIPVLLRESDSNHEINAKIKVV
CCCEEEEECCCHHHHHHHCCCEEEEEEEECCCCCCCCCCCCEEEEECCCCCEECEEEEEE
RKQKIGEKSYSVGAEFVELSNESQTKLADLYLLHQFKAKSPMGAVV
EHHHCCCHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]