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The map label for this gene is mcp4 [H]

Identifier: 183221986

GI number: 183221986

Start: 2719237

End: 2720817

Strand: Direct

Name: mcp4 [H]

Synonym: LEPBI_I2626

Alternate gene names: 183221986

Gene position: 2719237-2720817 (Clockwise)

Preceding gene: 183221985

Following gene: 183221987

Centisome position: 75.54

GC content: 37.76

Gene sequence:

>1581_bases
ATGGCATTAGAAACAGATGAAATCCAAAGGTTTGAACGAACACTCTTCCGAAAAGGTGTTTCGCTCATCGTTTATACAAA
ATATGGACTCGCGATCATCTTTCTCTTAGGAGTTGCCTCTAACTATGCCACAAAAAGTTTTATCCCCAACTTAATTGGTT
CTCTAGTTTTTTTAACCAATGCCTTGGTTCCTGGCTATCTTTTGAAAAAGGAAAAAGAAATTTCAAAGAGAATGGCTGCA
TCCATCATCTTCATCGACTTACTCATTATTCTATGTTTTTTTTATTTGGATATTTATAATAATTATACCAAAAACGACGC
AAGTAATACATTGAGTAGTGGGATATTTTATATCATCTTTATCTTCATTGCGATCTATTCTAGTTTTTTATTCGAAACCA
AATTGGTCATGGCAGTTGGATTGATTTCCACTCTTTTGTATCTCGGTGGAATTTACTTAACACATAAATTAGGTGCGGTT
TTCATTCCCAAACCATTCCCTGAAATGCTTCGGGCAAACCACATCATCGTCACAACTGAAATTCAAAAAATTATCTTTTA
TTTTGGCGTGATATTTAGTTTGCGATTTGTGGTTTCACTCATGAGAGAAATGCAAAATGATCTAAAGGCAAAACTAAAAG
AAAGTTTTCAAAAACAAAATTTTATCGAAAACAAATCGACTCAGTTGGAAAAATCGGCAAACACTCTCGCGTTGTCTGTC
GAAAAATTACAATCGATGTCTGACGAACTTCATAACCAATCACAAAACCAGGCTGCTTCCGTAGAAGAGATTTCTGCATC
TGTGGAAGAACTTTCTTCATCAGCAACAAGCTCTGCTAATTTGGTGGAAGACCAAGTCACACGCGTCAAAATTGTGGATC
AAAATTTTTTATCTCTTCAAAACTTGAGCGAAAGTGTCAAAACCAAAACCACACAAATTGCAAAGGATGTAAGTCATTCC
GCAGATTTCAGTAAAAAAGTCAAAATTTCGTCGGAAGAATTGAATGGAATTTACTCAGAACTGAACCAAGCATTTTCCAA
AGTGGAAGAAATCAACCAAATGATGTCGGAAATTGCCGATCAAACCAACTTACTTGCGTTAAATGCTTCGATTGAAGCAG
CCCGCGCTGGAGAACATGGCCGTGGTTTTGCAGTTGTTGCGCAAGAAGTGGCAAAATTAGCAGAACGTTCTCAATCCAAC
GCGGGAACCATTGCCAAAATTGTAAAAGATGCTGGTTTAAAGATCAACGAAGGAACTCGTTATTCCAAAGAAGTCAAATC
CCAAGTGGAAAATCAAAATAGTGAATTATTACGCATCGAAACGGAAATCCTAAGTTTGGAAGGCCATGTCACGGAACAGG
AAGTCCTAAATCAAAAACTCAGAAATACTTTTTCCGAACTCCATGTACTCTCTGAACAAATTGGGATCATAGCACAGGAA
CAAATGTCTGGGAGCCGAGAGATCAATCGGGCCATCACGGTCATCGACGAAACCACTCAAAAATTAGCGGATTCAGTCCA
ACTCCTCTATGAAGAGATTAGCGAAATCCACACCCAAGCAAAACAACTCCATCATGATTAG

Upstream 100 bases:

>100_bases
TTGAGGTTTTTCTTCCTCGACAATTTTCCTTTCTCTGGTTACAAACTTAGTTCCTTCAGAAATTGAAGCTTATTTTCGTC
AAAAAAGATGAGGGGAAAAC

Downstream 100 bases:

>100_bases
GGATTTAGATGAAACTGAATTTGGTTCTTCCCTAAAACCTGTCTTTACAAGAGTCTCTGCTGATAGATTTTTGGGATATT
GGCAATTTATTTCAAGTGCA

Product: putative methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 526; Mature: 525

Protein sequence:

>526_residues
MALETDEIQRFERTLFRKGVSLIVYTKYGLAIIFLLGVASNYATKSFIPNLIGSLVFLTNALVPGYLLKKEKEISKRMAA
SIIFIDLLIILCFFYLDIYNNYTKNDASNTLSSGIFYIIFIFIAIYSSFLFETKLVMAVGLISTLLYLGGIYLTHKLGAV
FIPKPFPEMLRANHIIVTTEIQKIIFYFGVIFSLRFVVSLMREMQNDLKAKLKESFQKQNFIENKSTQLEKSANTLALSV
EKLQSMSDELHNQSQNQAASVEEISASVEELSSSATSSANLVEDQVTRVKIVDQNFLSLQNLSESVKTKTTQIAKDVSHS
ADFSKKVKISSEELNGIYSELNQAFSKVEEINQMMSEIADQTNLLALNASIEAARAGEHGRGFAVVAQEVAKLAERSQSN
AGTIAKIVKDAGLKINEGTRYSKEVKSQVENQNSELLRIETEILSLEGHVTEQEVLNQKLRNTFSELHVLSEQIGIIAQE
QMSGSREINRAITVIDETTQKLADSVQLLYEEISEIHTQAKQLHHD

Sequences:

>Translated_526_residues
MALETDEIQRFERTLFRKGVSLIVYTKYGLAIIFLLGVASNYATKSFIPNLIGSLVFLTNALVPGYLLKKEKEISKRMAA
SIIFIDLLIILCFFYLDIYNNYTKNDASNTLSSGIFYIIFIFIAIYSSFLFETKLVMAVGLISTLLYLGGIYLTHKLGAV
FIPKPFPEMLRANHIIVTTEIQKIIFYFGVIFSLRFVVSLMREMQNDLKAKLKESFQKQNFIENKSTQLEKSANTLALSV
EKLQSMSDELHNQSQNQAASVEEISASVEELSSSATSSANLVEDQVTRVKIVDQNFLSLQNLSESVKTKTTQIAKDVSHS
ADFSKKVKISSEELNGIYSELNQAFSKVEEINQMMSEIADQTNLLALNASIEAARAGEHGRGFAVVAQEVAKLAERSQSN
AGTIAKIVKDAGLKINEGTRYSKEVKSQVENQNSELLRIETEILSLEGHVTEQEVLNQKLRNTFSELHVLSEQIGIIAQE
QMSGSREINRAITVIDETTQKLADSVQLLYEEISEIHTQAKQLHHD
>Mature_525_residues
ALETDEIQRFERTLFRKGVSLIVYTKYGLAIIFLLGVASNYATKSFIPNLIGSLVFLTNALVPGYLLKKEKEISKRMAAS
IIFIDLLIILCFFYLDIYNNYTKNDASNTLSSGIFYIIFIFIAIYSSFLFETKLVMAVGLISTLLYLGGIYLTHKLGAVF
IPKPFPEMLRANHIIVTTEIQKIIFYFGVIFSLRFVVSLMREMQNDLKAKLKESFQKQNFIENKSTQLEKSANTLALSVE
KLQSMSDELHNQSQNQAASVEEISASVEELSSSATSSANLVEDQVTRVKIVDQNFLSLQNLSESVKTKTTQIAKDVSHSA
DFSKKVKISSEELNGIYSELNQAFSKVEEINQMMSEIADQTNLLALNASIEAARAGEHGRGFAVVAQEVAKLAERSQSNA
GTIAKIVKDAGLKINEGTRYSKEVKSQVENQNSELLRIETEILSLEGHVTEQEVLNQKLRNTFSELHVLSEQIGIIAQEQ
MSGSREINRAITVIDETTQKLADSVQLLYEEISEIHTQAKQLHHD

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=244, Percent_Identity=25.8196721311475, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI2367378, Length=191, Percent_Identity=30.8900523560209, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1787690, Length=296, Percent_Identity=27.7027027027027, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788194, Length=305, Percent_Identity=24.9180327868852, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1789453, Length=257, Percent_Identity=29.9610894941634, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 58919; Mature: 58788

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALETDEIQRFERTLFRKGVSLIVYTKYGLAIIFLLGVASNYATKSFIPNLIGSLVFLTN
CCCCHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALVPGYLLKKEKEISKRMAASIIFIDLLIILCFFYLDIYNNYTKNDASNTLSSGIFYIIF
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
IFIAIYSSFLFETKLVMAVGLISTLLYLGGIYLTHKLGAVFIPKPFPEMLRANHIIVTTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHCCCCEEEEHH
IQKIIFYFGVIFSLRFVVSLMREMQNDLKAKLKESFQKQNFIENKSTQLEKSANTLALSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHH
EKLQSMSDELHNQSQNQAASVEEISASVEELSSSATSSANLVEDQVTRVKIVDQNFLSLQ
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEHHHHHHHHH
NLSESVKTKTTQIAKDVSHSADFSKKVKISSEELNGIYSELNQAFSKVEEINQMMSEIAD
HHHHHHHHHHHHHHHHHHHHCCCCHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
QTNLLALNASIEAARAGEHGRGFAVVAQEVAKLAERSQSNAGTIAKIVKDAGLKINEGTR
CCCEEEEECCHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEECCCCC
YSKEVKSQVENQNSELLRIETEILSLEGHVTEQEVLNQKLRNTFSELHVLSEQIGIIAQE
HHHHHHHHHHCCCCCEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QMSGSREINRAITVIDETTQKLADSVQLLYEEISEIHTQAKQLHHD
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ALETDEIQRFERTLFRKGVSLIVYTKYGLAIIFLLGVASNYATKSFIPNLIGSLVFLTN
CCCHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALVPGYLLKKEKEISKRMAASIIFIDLLIILCFFYLDIYNNYTKNDASNTLSSGIFYIIF
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
IFIAIYSSFLFETKLVMAVGLISTLLYLGGIYLTHKLGAVFIPKPFPEMLRANHIIVTTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHCCCCEEEEHH
IQKIIFYFGVIFSLRFVVSLMREMQNDLKAKLKESFQKQNFIENKSTQLEKSANTLALSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHH
EKLQSMSDELHNQSQNQAASVEEISASVEELSSSATSSANLVEDQVTRVKIVDQNFLSLQ
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEHHHHHHHHH
NLSESVKTKTTQIAKDVSHSADFSKKVKISSEELNGIYSELNQAFSKVEEINQMMSEIAD
HHHHHHHHHHHHHHHHHHHHCCCCHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
QTNLLALNASIEAARAGEHGRGFAVVAQEVAKLAERSQSNAGTIAKIVKDAGLKINEGTR
CCCEEEEECCHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEECCCCC
YSKEVKSQVENQNSELLRIETEILSLEGHVTEQEVLNQKLRNTFSELHVLSEQIGIIAQE
HHHHHHHHHHCCCCCEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QMSGSREINRAITVIDETTQKLADSVQLLYEEISEIHTQAKQLHHD
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]