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The map label for this gene is cdsA [H]

Identifier: 183221971

GI number: 183221971

Start: 2703568

End: 2704479

Strand: Reverse

Name: cdsA [H]

Synonym: LEPBI_I2612

Alternate gene names: 183221971

Gene position: 2704479-2703568 (Counterclockwise)

Preceding gene: 183221972

Following gene: 183221970

Centisome position: 75.13

GC content: 39.91

Gene sequence:

>912_bases
ATGAGTGAAACGACACTCCGTATTTTGTCTGCAATTGTACTCACTTTTGTATATGTATTCATGATCTTTCATAGTTCCTG
GTACTACTTGGAATTTTATACCTTTGGTGTTGTGATGATTTATCTCGGATTAAAAGAGTTGTATGCCTTCTGCAAAACAG
AAGAATCCAAACCATTTTTTGGAACTGGGTTACTCTTTTCCCTTTTGATCTTTACTGTGTATTACATCCAATTTTTGGGA
CTACAGTTTGAGGTCACACCTCCTGGATTTGTATTAGAGTTTTCCAAAATATTACGAGAAGGTTTCCATCCGATTCCTTT
TTTGTTAGTGGCACTCTCCATTACGGTTTGGATATTACAAATCCTGAAACGACCGTTAGATGGTGCACTTTTCTCAGTCG
GTGGAACCATGCTTGGTCCTATTTATATCGCGATTCCGATTGGGCATTTTTTATTGTTACTTGCACTTCCGTTTGGAGCT
TATTATATCTTCCTCGTTTCTGTGATCACATTTATGAGTGATGCGGGTGCGTATTTTGGTGGTCGTTGGTTTGGAAAACA
CCCAGCCGGCTTAAAAATTTCCCCGAAAAAAACATGGGAAGGATATGTTGTTGGAAACCTAACGGCTGTCATTGGGGCAC
AAGTTTTAAATTTTACTTGGGAACATTTCAGCGGTGTGAAGTTACCAGTGGGAATTTTAGAGACCATTATCTTATCCTTT
GTGATTTCTGTGATTTCTGTCATGGGAGATTTGGCAGAGTCAGCCATGAAACGGGATGCCAAAATCAAAGACTCAGGAAG
TCTTATCCCTGGCCACGGCGGAATTCTCGATTTAGCAGATGCACTCCTTTTCACTGTGCCTGCGATTTATTATTATTTAG
TTTTCAAAGGTTTCCTTGGATTCCCCGTCTGA

Upstream 100 bases:

>100_bases
TGTATTTTACGAGTACACTTTGGCCTGACTTTGGAAGGACCTCACTCGAGGAAGCTCTTCTTTTTTTTGATTCCCGAAAA
CGTAAATTTGGTGGTTTGTT

Downstream 100 bases:

>100_bases
TTCATTTGAATCAGACTGTCTAAGTTCTATATGGTAGGTGTTTCGGTATTAGGAATCTCTGGTTCTGTTGGTACTTCCAC
AGTGAAGGTACTCCGACAAT

Product: phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MSETTLRILSAIVLTFVYVFMIFHSSWYYLEFYTFGVVMIYLGLKELYAFCKTEESKPFFGTGLLFSLLIFTVYYIQFLG
LQFEVTPPGFVLEFSKILREGFHPIPFLLVALSITVWILQILKRPLDGALFSVGGTMLGPIYIAIPIGHFLLLLALPFGA
YYIFLVSVITFMSDAGAYFGGRWFGKHPAGLKISPKKTWEGYVVGNLTAVIGAQVLNFTWEHFSGVKLPVGILETIILSF
VISVISVMGDLAESAMKRDAKIKDSGSLIPGHGGILDLADALLFTVPAIYYYLVFKGFLGFPV

Sequences:

>Translated_303_residues
MSETTLRILSAIVLTFVYVFMIFHSSWYYLEFYTFGVVMIYLGLKELYAFCKTEESKPFFGTGLLFSLLIFTVYYIQFLG
LQFEVTPPGFVLEFSKILREGFHPIPFLLVALSITVWILQILKRPLDGALFSVGGTMLGPIYIAIPIGHFLLLLALPFGA
YYIFLVSVITFMSDAGAYFGGRWFGKHPAGLKISPKKTWEGYVVGNLTAVIGAQVLNFTWEHFSGVKLPVGILETIILSF
VISVISVMGDLAESAMKRDAKIKDSGSLIPGHGGILDLADALLFTVPAIYYYLVFKGFLGFPV
>Mature_302_residues
SETTLRILSAIVLTFVYVFMIFHSSWYYLEFYTFGVVMIYLGLKELYAFCKTEESKPFFGTGLLFSLLIFTVYYIQFLGL
QFEVTPPGFVLEFSKILREGFHPIPFLLVALSITVWILQILKRPLDGALFSVGGTMLGPIYIAIPIGHFLLLLALPFGAY
YIFLVSVITFMSDAGAYFGGRWFGKHPAGLKISPKKTWEGYVVGNLTAVIGAQVLNFTWEHFSGVKLPVGILETIILSFV
ISVISVMGDLAESAMKRDAKIKDSGSLIPGHGGILDLADALLFTVPAIYYYLVFKGFLGFPV

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=140, Percent_Identity=43.5714285714286, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1787677, Length=181, Percent_Identity=31.4917127071823, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 33724; Mature: 33592

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETTLRILSAIVLTFVYVFMIFHSSWYYLEFYTFGVVMIYLGLKELYAFCKTEESKPFF
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GTGLLFSLLIFTVYYIQFLGLQFEVTPPGFVLEFSKILREGFHPIPFLLVALSITVWILQ
HHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
ILKRPLDGALFSVGGTMLGPIYIAIPIGHFLLLLALPFGAYYIFLVSVITFMSDAGAYFG
HHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHC
GRWFGKHPAGLKISPKKTWEGYVVGNLTAVIGAQVLNFTWEHFSGVKLPVGILETIILSF
CCCCCCCCCCCEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
VISVISVMGDLAESAMKRDAKIKDSGSLIPGHGGILDLADALLFTVPAIYYYLVFKGFLG
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
FPV
CCC
>Mature Secondary Structure 
SETTLRILSAIVLTFVYVFMIFHSSWYYLEFYTFGVVMIYLGLKELYAFCKTEESKPFF
CHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC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CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]