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The map label for this gene is groES

Identifier: 183221714

GI number: 183221714

Start: 2415252

End: 2415542

Strand: Direct

Name: groES

Synonym: LEPBI_I2343

Alternate gene names: 183221714

Gene position: 2415252-2415542 (Clockwise)

Preceding gene: 183221713

Following gene: 183221715

Centisome position: 67.1

GC content: 45.36

Gene sequence:

>291_bases
ATGGCGTCAATTAAACCTTTAGGCGACCGAGTCGTCGTCGAGCCTAAGAATGAGTCGGAAGAAAAAATCGGATCCATCAT
CGTCCCAGACACGGCCAAAGAAAAACCACAAGAAGGCAAAGTCATCGCTGCGGGACAAGGCCGTTACGAAGACGGTAAAC
TCGTTCCTTTAGAAGTAAAGGTTGGGGATACAGTTCTATACGGAAAGTATTCTGGAACAGAAATCAAACAAGGCGGAAAA
GATTTACTCATTATCCGTGAAAGCGACATCCTCGGTGTCGTAACAAACTAA

Upstream 100 bases:

>100_bases
ATCCTTCCTCCAATCATTCTATGGTACTTGAGTTTAGCACTCTTTTTGAAATGGTGCTAAACTTAGTATTAATCAGTAGA
ATGCATACAAGGAGTCACTC

Downstream 100 bases:

>100_bases
TCATAAAAGGGAATCATTAACCATGGCTAAAACAATCGAATTTGATGAAACAGCACGTAGAAAACTTCTTAGCGGAGTGA
ACAAACTCGCTAACGCAGTG

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Protein Cpn10

Number of amino acids: Translated: 96; Mature: 95

Protein sequence:

>96_residues
MASIKPLGDRVVVEPKNESEEKIGSIIVPDTAKEKPQEGKVIAAGQGRYEDGKLVPLEVKVGDTVLYGKYSGTEIKQGGK
DLLIIRESDILGVVTN

Sequences:

>Translated_96_residues
MASIKPLGDRVVVEPKNESEEKIGSIIVPDTAKEKPQEGKVIAAGQGRYEDGKLVPLEVKVGDTVLYGKYSGTEIKQGGK
DLLIIRESDILGVVTN
>Mature_95_residues
ASIKPLGDRVVVEPKNESEEKIGSIIVPDTAKEKPQEGKVIAAGQGRYEDGKLVPLEVKVGDTVLYGKYSGTEIKQGGKD
LLIIRESDILGVVTN

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family

Homologues:

Organism=Escherichia coli, GI1790585, Length=94, Percent_Identity=40.4255319148936, Blast_Score=64, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17555568, Length=95, Percent_Identity=43.1578947368421, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): CH10_LEPBA (B0SCB9)

Other databases:

- EMBL:   CP000777
- RefSeq:   YP_001963344.1
- ProteinModelPortal:   B0SCB9
- SMR:   B0SCB9
- GeneID:   6389529
- GenomeReviews:   CP000777_GR
- KEGG:   lbf:LBF_2273
- HOGENOM:   HBG703377
- OMA:   QDRIIVK
- ProtClustDB:   PRK00364
- BioCyc:   LBIF355278:LBF_2273-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00580
- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032
- Gene3D:   G3DSA:2.30.33.40
- PANTHER:   PTHR10772
- PRINTS:   PR00297
- SMART:   SM00883

Pfam domain/function: PF00166 Cpn10; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 10307; Mature: 10176

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASIKPLGDRVVVEPKNESEEKIGSIIVPDTAKEKPQEGKVIAAGQGRYEDGKLVPLEVK
CCCCCCCCCEEEECCCCCCCCCCCEEECCCCCCCCCCCCCEEEECCCCCCCCCEEEEEEE
VGDTVLYGKYSGTEIKQGGKDLLIIRESDILGVVTN
ECCEEEEECCCCCCCCCCCCEEEEEECCCEEEEEEC
>Mature Secondary Structure 
ASIKPLGDRVVVEPKNESEEKIGSIIVPDTAKEKPQEGKVIAAGQGRYEDGKLVPLEVK
CCCCCCCCEEEECCCCCCCCCCCEEECCCCCCCCCCCCCEEEECCCCCCCCCEEEEEEE
VGDTVLYGKYSGTEIKQGGKDLLIIRESDILGVVTN
ECCEEEEECCCCCCCCCCCCEEEEEECCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA