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The map label for this gene is argD [H]

Identifier: 183221691

GI number: 183221691

Start: 2386263

End: 2387480

Strand: Direct

Name: argD [H]

Synonym: LEPBI_I2316

Alternate gene names: 183221691

Gene position: 2386263-2387480 (Clockwise)

Preceding gene: 183221690

Following gene: 183221692

Centisome position: 66.29

GC content: 40.15

Gene sequence:

>1218_bases
ATGAGTTCCGAAACAAAAACCAAATTCGAAAGTATCAAAAATCTTTCTGACAAATACCTACTCAATACTTATAACAGATA
TCCAATCGCCTTCTCCTATGGTGTAGGTGAAATGATATTTGACCAAGATAACAATGGTTATATTGATTTTCTTGCAGGCA
TCGCAGTGTCAAACCTTGGCCATGGTGAAGCCGATCTAATTGAAGCTCTTCGAAACCAAATGGATAAAATCCTTCATTCT
TCCAATTTATATTATTCGGAAGAACAAGCAAAACTTGCAGAAGTTATCATTGAAAATAGTATCCCAGGAAAAGTTTTTTT
ATGCAACTCAGGAACAGAAGCCAACGAAGCTGCATTTAAACTCATGCGCCGACATGGGATCAACCAAAACATTGAAAAAC
CAGTTATTTTAGCGCTCCAATCCAGTTTTCATGGTAGAACCTTATCGGCGATGTCGATGACTGGAAACGAATCGGTGAGG
TCAGGATTTGGAGAACTCGCAGCTGACATTCATTTTGTGGAAGCAAATAACGAAGATTCTCTCATCCAAGCCTTTGAACA
ATACGGAGGTTCCGTTGCTGGTATCATTATGGAACTTATTATCGGCGAAGGTGGAGTGATCCCACTCTCTCATTCCTTTG
TGAATTTGGCTCGTAAACTTACAGAAGAAACCAACTCACTGCTTGTCTTTGATGAAATCCAAACGGGAATGGGAAGAACA
GGAAAGATGTTTTGTTTTGAACATTACGGAATGTATCCAGATGCGTTCACTCTTGCCAAAGCATTGGGATCGGGATTTCC
AATAGGTGCTCTTGTTGTCTCCAAAGAATATGAATCCGTATTGGAACGAGGGATGCATGGTTCCACATTTGGTGGAAACC
ACTTGGCCTGTGTAGCCGCTTACGAGACATTTAAGATCATACTTTCAAGAAACCTTCTCGACCATGTTTCTACCATCTCA
GAACAAATGTTCCATCGATTGAAACAAATCATGGAATCCACAGGCAAAATCAAAGAAGTCCGCGGGCGAGGGCTTCATAT
TGGTGTGGAGTTGTATTCGGAATCAAGACCAGTTGTTGAAGAATGTTTGAAACGTGGCCTTGTTGTCAATAGTACAGCTG
GAAAAGTCATTCGTATCATACCTCCACTCATCTTGAGCATTGAAAAAGCAACAGAAGGGTTGGATATTTTAGAATCAGTT
TTAAAGGAAATGAAATGA

Upstream 100 bases:

>100_bases
AAAAACCGAAAAAATCTTCAGAGATCCCTAGTTTATGGAAAACTTTGGGAGATGAGATTGTTTCCGCAGAAACTGAATTT
TTACAACTAGCAGGCCTACT

Downstream 100 bases:

>100_bases
AAAAAGTTGCAGTTCTTGCCGGTGATGGTATCGGTCCGGAAGTTATGGAAGTGGCCCTACAGGTAGTAGGGAAAGCATTA
GGAAACAAACGTAGCGAATT

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MSSETKTKFESIKNLSDKYLLNTYNRYPIAFSYGVGEMIFDQDNNGYIDFLAGIAVSNLGHGEADLIEALRNQMDKILHS
SNLYYSEEQAKLAEVIIENSIPGKVFLCNSGTEANEAAFKLMRRHGINQNIEKPVILALQSSFHGRTLSAMSMTGNESVR
SGFGELAADIHFVEANNEDSLIQAFEQYGGSVAGIIMELIIGEGGVIPLSHSFVNLARKLTEETNSLLVFDEIQTGMGRT
GKMFCFEHYGMYPDAFTLAKALGSGFPIGALVVSKEYESVLERGMHGSTFGGNHLACVAAYETFKIILSRNLLDHVSTIS
EQMFHRLKQIMESTGKIKEVRGRGLHIGVELYSESRPVVEECLKRGLVVNSTAGKVIRIIPPLILSIEKATEGLDILESV
LKEMK

Sequences:

>Translated_405_residues
MSSETKTKFESIKNLSDKYLLNTYNRYPIAFSYGVGEMIFDQDNNGYIDFLAGIAVSNLGHGEADLIEALRNQMDKILHS
SNLYYSEEQAKLAEVIIENSIPGKVFLCNSGTEANEAAFKLMRRHGINQNIEKPVILALQSSFHGRTLSAMSMTGNESVR
SGFGELAADIHFVEANNEDSLIQAFEQYGGSVAGIIMELIIGEGGVIPLSHSFVNLARKLTEETNSLLVFDEIQTGMGRT
GKMFCFEHYGMYPDAFTLAKALGSGFPIGALVVSKEYESVLERGMHGSTFGGNHLACVAAYETFKIILSRNLLDHVSTIS
EQMFHRLKQIMESTGKIKEVRGRGLHIGVELYSESRPVVEECLKRGLVVNSTAGKVIRIIPPLILSIEKATEGLDILESV
LKEMK
>Mature_404_residues
SSETKTKFESIKNLSDKYLLNTYNRYPIAFSYGVGEMIFDQDNNGYIDFLAGIAVSNLGHGEADLIEALRNQMDKILHSS
NLYYSEEQAKLAEVIIENSIPGKVFLCNSGTEANEAAFKLMRRHGINQNIEKPVILALQSSFHGRTLSAMSMTGNESVRS
GFGELAADIHFVEANNEDSLIQAFEQYGGSVAGIIMELIIGEGGVIPLSHSFVNLARKLTEETNSLLVFDEIQTGMGRTG
KMFCFEHYGMYPDAFTLAKALGSGFPIGALVVSKEYESVLERGMHGSTFGGNHLACVAAYETFKIILSRNLLDHVSTISE
QMFHRLKQIMESTGKIKEVRGRGLHIGVELYSESRPVVEECLKRGLVVNSTAGKVIRIIPPLILSIEKATEGLDILESVL
KEMK

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=393, Percent_Identity=28.7531806615776, Blast_Score=178, Evalue=8e-45,
Organism=Homo sapiens, GI13994255, Length=439, Percent_Identity=26.6514806378132, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI284507298, Length=302, Percent_Identity=28.8079470198675, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI24119277, Length=417, Percent_Identity=23.9808153477218, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI37574042, Length=414, Percent_Identity=25.3623188405797, Blast_Score=118, Evalue=9e-27,
Organism=Homo sapiens, GI226442705, Length=414, Percent_Identity=25.3623188405797, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI226442709, Length=383, Percent_Identity=25.5874673629243, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI188536080, Length=307, Percent_Identity=24.7557003257329, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI38679950, Length=307, Percent_Identity=24.7557003257329, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI38679946, Length=307, Percent_Identity=24.7557003257329, Blast_Score=76, Evalue=6e-14,
Organism=Escherichia coli, GI1788044, Length=384, Percent_Identity=39.3229166666667, Blast_Score=273, Evalue=1e-74,
Organism=Escherichia coli, GI1789759, Length=383, Percent_Identity=36.0313315926893, Blast_Score=244, Evalue=6e-66,
Organism=Escherichia coli, GI145693181, Length=377, Percent_Identity=35.5437665782493, Blast_Score=203, Evalue=1e-53,
Organism=Escherichia coli, GI1789016, Length=397, Percent_Identity=29.2191435768262, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1787560, Length=392, Percent_Identity=31.1224489795918, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1786991, Length=390, Percent_Identity=26.6666666666667, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1786349, Length=312, Percent_Identity=25, Blast_Score=87, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI25144271, Length=397, Percent_Identity=28.7153652392947, Blast_Score=182, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI32564660, Length=436, Percent_Identity=28.6697247706422, Blast_Score=171, Evalue=6e-43,
Organism=Caenorhabditis elegans, GI71992977, Length=432, Percent_Identity=25.6944444444444, Blast_Score=133, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI25144274, Length=267, Percent_Identity=29.2134831460674, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17541228, Length=452, Percent_Identity=23.8938053097345, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71981843, Length=173, Percent_Identity=27.1676300578035, Blast_Score=75, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6324432, Length=398, Percent_Identity=37.6884422110553, Blast_Score=274, Evalue=2e-74,
Organism=Saccharomyces cerevisiae, GI6323470, Length=422, Percent_Identity=31.2796208530806, Blast_Score=197, Evalue=3e-51,
Organism=Saccharomyces cerevisiae, GI6324386, Length=455, Percent_Identity=28.1318681318681, Blast_Score=124, Evalue=3e-29,
Organism=Drosophila melanogaster, GI21357415, Length=397, Percent_Identity=29.2191435768262, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI28574759, Length=435, Percent_Identity=28.9655172413793, Blast_Score=164, Evalue=9e-41,
Organism=Drosophila melanogaster, GI161085790, Length=434, Percent_Identity=29.2626728110599, Blast_Score=161, Evalue=6e-40,
Organism=Drosophila melanogaster, GI21356575, Length=460, Percent_Identity=25, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI281366494, Length=427, Percent_Identity=24.1217798594848, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24667139, Length=427, Percent_Identity=24.1217798594848, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24667143, Length=427, Percent_Identity=24.1217798594848, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 44652; Mature: 44521

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSETKTKFESIKNLSDKYLLNTYNRYPIAFSYGVGEMIFDQDNNGYIDFLAGIAVSNLG
CCCCHHHHHHHHHCCCHHHHHHCCCCCCEEEECCCCCEEEECCCCCHHHHHHHHHHHCCC
HGEADLIEALRNQMDKILHSSNLYYSEEQAKLAEVIIENSIPGKVFLCNSGTEANEAAFK
CCHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHH
LMRRHGINQNIEKPVILALQSSFHGRTLSAMSMTGNESVRSGFGELAADIHFVEANNEDS
HHHHCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHEEEEEECCCCHH
LIQAFEQYGGSVAGIIMELIIGEGGVIPLSHSFVNLARKLTEETNSLLVFDEIQTGMGRT
HHHHHHHHCCHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHCCCEEEEECHHHCCCCC
GKMFCFEHYGMYPDAFTLAKALGSGFPIGALVVSKEYESVLERGMHGSTFGGNHLACVAA
CCEEEEHHCCCCCHHHHHHHHHCCCCCHHHHEECHHHHHHHHCCCCCCCCCCCCEEEEEH
YETFKIILSRNLLDHVSTISEQMFHRLKQIMESTGKIKEVRGRGLHIGVELYSESRPVVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCEEEEEEEECCCCCHHH
ECLKRGLVVNSTAGKVIRIIPPLILSIEKATEGLDILESVLKEMK
HHHHCCEEEECCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHCC
>Mature Secondary Structure 
SSETKTKFESIKNLSDKYLLNTYNRYPIAFSYGVGEMIFDQDNNGYIDFLAGIAVSNLG
CCCHHHHHHHHHCCCHHHHHHCCCCCCEEEECCCCCEEEECCCCCHHHHHHHHHHHCCC
HGEADLIEALRNQMDKILHSSNLYYSEEQAKLAEVIIENSIPGKVFLCNSGTEANEAAFK
CCHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHH
LMRRHGINQNIEKPVILALQSSFHGRTLSAMSMTGNESVRSGFGELAADIHFVEANNEDS
HHHHCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHEEEEEECCCCHH
LIQAFEQYGGSVAGIIMELIIGEGGVIPLSHSFVNLARKLTEETNSLLVFDEIQTGMGRT
HHHHHHHHCCHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHCCCEEEEECHHHCCCCC
GKMFCFEHYGMYPDAFTLAKALGSGFPIGALVVSKEYESVLERGMHGSTFGGNHLACVAA
CCEEEEHHCCCCCHHHHHHHHHCCCCCHHHHEECHHHHHHHHCCCCCCCCCCCCEEEEEH
YETFKIILSRNLLDHVSTISEQMFHRLKQIMESTGKIKEVRGRGLHIGVELYSESRPVVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCEEEEEEEECCCCCHHH
ECLKRGLVVNSTAGKVIRIIPPLILSIEKATEGLDILESVLKEMK
HHHHCCEEEECCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA