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The map label for this gene is 183221193

Identifier: 183221193

GI number: 183221193

Start: 1887509

End: 1889542

Strand: Direct

Name: 183221193

Synonym: LEPBI_I1807

Alternate gene names: NA

Gene position: 1887509-1889542 (Clockwise)

Preceding gene: 183221191

Following gene: 183221194

Centisome position: 52.44

GC content: 36.18

Gene sequence:

>2034_bases
TTGCGAAAGTTTGTCACTACTATCTTTCTTTTGGTCTGCACCCAAATTTTACCTCTAGACTTTCCCAATTTTTCTTTGGG
TGAAGAGAATGCCAAGGAAGAATTCAAACGGGGACTCACTTATAAAAATTTAAGAGAGTATTCTGCCGCAAAAGAACGTT
TTCAAAAAGCTGTTAATTTAAAAAAAGATTTCCATTTAGCTCGGCTTGAGCTATCCAATAACTACTATTTGTTAGGCGAA
TGGGAGGAAGCTCTCGATGAATTGGAAATTTTAGCCACTAAGGCTAAAAATGATTTACTCATTTCCAATAAAATAGAAAC
ACTACGGCTTGCCATTGCAGGTGGTGTGACGGAAAAAGAAAAAATATATTTTAAAACCATTGAAGGAGATTCCATTCGTG
GTTTCCGATTTCGTAATCCTGTTGATATAACATTTGATGAAGACGGAAATTTTTATGTGGCTGGATTTGATACATCCAAC
GTCATTAAATTCAATGCAGCAGGAACTCCAATTTCTAATTGGAGAGGCGGAATCACTCGTAAACTAGAAAGGCCAGTCTC
ACTTGTATATCAAAACCAAAAAATTTATATCGCTGACTTTCTTCGTGATGAAGTTTTGATTTTTGATTTAAATGGTAGTT
TTTTATCTTCCATCGGCGGACCAGGCAAAGGACCTGGTCAATTCAGAGGCCCCTCTTCCATTTGTTTTGATCGATCTGGT
AATTTATTTGTAGCGGATTCAGGAAATGGTCGAATCCAAAAGTTCAATTCGAATGGGCAATTTGTATTAGAAATTTCTGG
AATGGGAAATTCAAAATTAATCAATCCATCTGGGATTACGGTCGATGCAAATAAACTGTATGTAGTTGATAAAGACAAAG
TTCAAGTACATATTTTTGATGGTGATGGTAATACTTTGGAAACCATCTCCAAACCTGAATGGAAAAAACCTCGTAATATC
AAAATTTTAGAAAATCAAATATTTTTAACTGATGAACTCACTGGTATATGGACCTACTCTCTGTTAAATGGTGATTGGAC
CCAACTTCCTAAATTTCGAGATAAAAAGGGTGTATATCGAGTATTATTTCGGCCATTTGCGGCCAATATGGATGGGACGG
GAAGTTTATATTTCGTTGATTTTGGAAAACATAGAATCGATATATTTTCCCAAAAAAACAATCTCCTATCCAATTTGGAT
TTGAAAATTGAATCCATTGATACCTCTGATTTTCCCAATATTCACATTTACACTCGAGTCAAAAACAGAGGTGGAAAAGA
ATTGGTAGGAATCGATCGATTAAGTTTTCGAATATTCGAGAATGATAATATGACTCCCTTATTTTCACTCGCGAATAAAA
ACAAAGTAAATGAAAAATTGAATCTCGCTATCATATACGAAAATAGTGAATCTTTAAAAAAAGGAAAACTGAGCTTAGAG
GATGGACTATTCCCCCTGTTTCGTTCCTTACATGATACGGATCACGTGGCGGTTTATCGTGCAGGAAAAGATAGCCAGCT
CATCTTGCGAGAAACCGTGTCCCTCCGAGATATTTTGGCAAAAATTAGAGACGGCCAACCAGAAGAGAAACATAATTTTG
GAAAGGCAAGTATCGCCGCTTTAAAAAAGTTATCAATGGAAATTGGTCCAAAAGCCTTGGTTTATTTAGTTTCAAAAGAG
GCAAAAGAAGATAGTTTTTACCAATACCAAAAATCAAGAATTGTCACTTATGCAAAAGCCCACTCCATTCCTATCTATGT
ATTAACAACCAATCCAAATCCATCCTATGAAGAATCCTGGTCAGATATCACAAGTCCTACCAATGGAAAGTATATCTATT
TGGATGGTGAAGGTGAGGAACGTGAATTGTACAAACAATTCAGATCGCATTTGGATTATCGTTACATCCTTTCTTACAAA
ACAGACACAAATCCAGAACTCATCAACCGGTACATCAAAATTGGAATTGGAGTGAATCATCGAGGGGTCAAAGGCCGAGA
TGAAGGAGGTTATTTTGTTCCAGAACCTCGTTAG

Upstream 100 bases:

>100_bases
CGATTCTGTCGAGAATAAAGAAAGAATCAGGTTCCTTTCCCCAAGGAAGGGTTGACTCTAGAATTATGTCCCTTTAAACT
GGGGACAGAGGGAGAGTTTT

Downstream 100 bases:

>100_bases
CCGAAAACTCAAATTTTTATCTGTTTTGGTATTGGGATTCACTACCAATATTATTTTTGCTGAAAGTACAGCCTTGGAAG
ATATTGCAGAGGCAAAAATT

Product: hypothetical protein

Products: NA

Alternate protein names: NHL Repeat-Containing Protein; Tripartite Motif-Containing Protein; PA14 Domain-Containing Protein; Tetratricopeptide Repeat Family Protein; Tetratricopeptide Repeat-Containing Protein; NHL Repeat Protein; PKD Domain Containing Protein; Cell Surface Protein; Surface Layer Protein

Number of amino acids: Translated: 677; Mature: 677

Protein sequence:

>677_residues
MRKFVTTIFLLVCTQILPLDFPNFSLGEENAKEEFKRGLTYKNLREYSAAKERFQKAVNLKKDFHLARLELSNNYYLLGE
WEEALDELEILATKAKNDLLISNKIETLRLAIAGGVTEKEKIYFKTIEGDSIRGFRFRNPVDITFDEDGNFYVAGFDTSN
VIKFNAAGTPISNWRGGITRKLERPVSLVYQNQKIYIADFLRDEVLIFDLNGSFLSSIGGPGKGPGQFRGPSSICFDRSG
NLFVADSGNGRIQKFNSNGQFVLEISGMGNSKLINPSGITVDANKLYVVDKDKVQVHIFDGDGNTLETISKPEWKKPRNI
KILENQIFLTDELTGIWTYSLLNGDWTQLPKFRDKKGVYRVLFRPFAANMDGTGSLYFVDFGKHRIDIFSQKNNLLSNLD
LKIESIDTSDFPNIHIYTRVKNRGGKELVGIDRLSFRIFENDNMTPLFSLANKNKVNEKLNLAIIYENSESLKKGKLSLE
DGLFPLFRSLHDTDHVAVYRAGKDSQLILRETVSLRDILAKIRDGQPEEKHNFGKASIAALKKLSMEIGPKALVYLVSKE
AKEDSFYQYQKSRIVTYAKAHSIPIYVLTTNPNPSYEESWSDITSPTNGKYIYLDGEGEERELYKQFRSHLDYRYILSYK
TDTNPELINRYIKIGIGVNHRGVKGRDEGGYFVPEPR

Sequences:

>Translated_677_residues
MRKFVTTIFLLVCTQILPLDFPNFSLGEENAKEEFKRGLTYKNLREYSAAKERFQKAVNLKKDFHLARLELSNNYYLLGE
WEEALDELEILATKAKNDLLISNKIETLRLAIAGGVTEKEKIYFKTIEGDSIRGFRFRNPVDITFDEDGNFYVAGFDTSN
VIKFNAAGTPISNWRGGITRKLERPVSLVYQNQKIYIADFLRDEVLIFDLNGSFLSSIGGPGKGPGQFRGPSSICFDRSG
NLFVADSGNGRIQKFNSNGQFVLEISGMGNSKLINPSGITVDANKLYVVDKDKVQVHIFDGDGNTLETISKPEWKKPRNI
KILENQIFLTDELTGIWTYSLLNGDWTQLPKFRDKKGVYRVLFRPFAANMDGTGSLYFVDFGKHRIDIFSQKNNLLSNLD
LKIESIDTSDFPNIHIYTRVKNRGGKELVGIDRLSFRIFENDNMTPLFSLANKNKVNEKLNLAIIYENSESLKKGKLSLE
DGLFPLFRSLHDTDHVAVYRAGKDSQLILRETVSLRDILAKIRDGQPEEKHNFGKASIAALKKLSMEIGPKALVYLVSKE
AKEDSFYQYQKSRIVTYAKAHSIPIYVLTTNPNPSYEESWSDITSPTNGKYIYLDGEGEERELYKQFRSHLDYRYILSYK
TDTNPELINRYIKIGIGVNHRGVKGRDEGGYFVPEPR
>Mature_677_residues
MRKFVTTIFLLVCTQILPLDFPNFSLGEENAKEEFKRGLTYKNLREYSAAKERFQKAVNLKKDFHLARLELSNNYYLLGE
WEEALDELEILATKAKNDLLISNKIETLRLAIAGGVTEKEKIYFKTIEGDSIRGFRFRNPVDITFDEDGNFYVAGFDTSN
VIKFNAAGTPISNWRGGITRKLERPVSLVYQNQKIYIADFLRDEVLIFDLNGSFLSSIGGPGKGPGQFRGPSSICFDRSG
NLFVADSGNGRIQKFNSNGQFVLEISGMGNSKLINPSGITVDANKLYVVDKDKVQVHIFDGDGNTLETISKPEWKKPRNI
KILENQIFLTDELTGIWTYSLLNGDWTQLPKFRDKKGVYRVLFRPFAANMDGTGSLYFVDFGKHRIDIFSQKNNLLSNLD
LKIESIDTSDFPNIHIYTRVKNRGGKELVGIDRLSFRIFENDNMTPLFSLANKNKVNEKLNLAIIYENSESLKKGKLSLE
DGLFPLFRSLHDTDHVAVYRAGKDSQLILRETVSLRDILAKIRDGQPEEKHNFGKASIAALKKLSMEIGPKALVYLVSKE
AKEDSFYQYQKSRIVTYAKAHSIPIYVLTTNPNPSYEESWSDITSPTNGKYIYLDGEGEERELYKQFRSHLDYRYILSYK
TDTNPELINRYIKIGIGVNHRGVKGRDEGGYFVPEPR

Specific function: Unknown

COG id: COG3391

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI32454739, Length=157, Percent_Identity=30.5732484076433, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI32454737, Length=157, Percent_Identity=30.5732484076433, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI194248081, Length=157, Percent_Identity=30.5732484076433, Blast_Score=77, Evalue=7e-14,
Organism=Homo sapiens, GI194248079, Length=157, Percent_Identity=30.5732484076433, Blast_Score=77, Evalue=7e-14,
Organism=Homo sapiens, GI84993742, Length=159, Percent_Identity=25.7861635220126, Blast_Score=68, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17553622, Length=189, Percent_Identity=31.2169312169312, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI115533679, Length=140, Percent_Identity=29.2857142857143, Blast_Score=66, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24655386, Length=171, Percent_Identity=32.7485380116959, Blast_Score=87, Evalue=5e-17,
Organism=Drosophila melanogaster, GI22024206, Length=171, Percent_Identity=32.7485380116959, Blast_Score=87, Evalue=5e-17,
Organism=Drosophila melanogaster, GI221330419, Length=171, Percent_Identity=32.7485380116959, Blast_Score=87, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 77147; Mature: 77147

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: PS51125 NHL L=RR ; PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKFVTTIFLLVCTQILPLDFPNFSLGEENAKEEFKRGLTYKNLREYSAAKERFQKAVNL
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
KKDFHLARLELSNNYYLLGEWEEALDELEILATKAKNDLLISNKIETLRLAIAGGVTEKE
CCCCEEEEEEECCCEEEEECHHHHHHHHHHHHHCCCCCEEEECCCEEEEEEEECCCCCCC
KIYFKTIEGDSIRGFRFRNPVDITFDEDGNFYVAGFDTSNVIKFNAAGTPISNWRGGITR
EEEEEEECCCCCCCEEECCCEEEEECCCCCEEEEEECCCCEEEEECCCCCHHCCCCCHHH
KLERPVSLVYQNQKIYIADFLRDEVLIFDLNGSFLSSIGGPGKGPGQFRGPSSICFDRSG
HHCCCEEEEEECCEEEEEEECCCEEEEEECCCHHHHHCCCCCCCCCCCCCCCCEEEECCC
NLFVADSGNGRIQKFNSNGQFVLEISGMGNSKLINPSGITVDANKLYVVDKDKVQVHIFD
CEEEEECCCCEEEEECCCCCEEEEEECCCCCEEECCCCCEEECCEEEEEECCCEEEEEEC
GDGNTLETISKPEWKKPRNIKILENQIFLTDELTGIWTYSLLNGDWTQLPKFRDKKGVYR
CCCCEEECCCCCCCCCCCCEEEEECEEEEEECCCEEEEEEEECCCHHHCCCCCCCCCCEE
VLFRPFAANMDGTGSLYFVDFGKHRIDIFSQKNNLLSNLDLKIESIDTSDFPNIHIYTRV
EEEHHHHCCCCCCCCEEEEECCCEEEEEEECCCCCHHCCCEEEEECCCCCCCCEEEEEEE
KNRGGKELVGIDRLSFRIFENDNMTPLFSLANKNKVNEKLNLAIIYENSESLKKGKLSLE
CCCCCCEEEEEEEEEEEEEECCCCCEEEEECCCCCCCCEEEEEEEEECCCCHHHCCCCHH
DGLFPLFRSLHDTDHVAVYRAGKDSQLILRETVSLRDILAKIRDGQPEEKHNFGKASIAA
CCHHHHHHHHCCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHH
LKKLSMEIGPKALVYLVSKEAKEDSFYQYQKSRIVTYAKAHSIPIYVLTTNPNPSYEESW
HHHHHHHCCCCEEEEEEECCCCCCHHHHHHHCEEEEEEECCCCEEEEEECCCCCCHHHHH
SDITSPTNGKYIYLDGEGEERELYKQFRSHLDYRYILSYKTDTNPELINRYIKIGIGVNH
HHCCCCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHEEEEECCCC
RGVKGRDEGGYFVPEPR
CCCCCCCCCCEECCCCC
>Mature Secondary Structure
MRKFVTTIFLLVCTQILPLDFPNFSLGEENAKEEFKRGLTYKNLREYSAAKERFQKAVNL
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
KKDFHLARLELSNNYYLLGEWEEALDELEILATKAKNDLLISNKIETLRLAIAGGVTEKE
CCCCEEEEEEECCCEEEEECHHHHHHHHHHHHHCCCCCEEEECCCEEEEEEEECCCCCCC
KIYFKTIEGDSIRGFRFRNPVDITFDEDGNFYVAGFDTSNVIKFNAAGTPISNWRGGITR
EEEEEEECCCCCCCEEECCCEEEEECCCCCEEEEEECCCCEEEEECCCCCHHCCCCCHHH
KLERPVSLVYQNQKIYIADFLRDEVLIFDLNGSFLSSIGGPGKGPGQFRGPSSICFDRSG
HHCCCEEEEEECCEEEEEEECCCEEEEEECCCHHHHHCCCCCCCCCCCCCCCCEEEECCC
NLFVADSGNGRIQKFNSNGQFVLEISGMGNSKLINPSGITVDANKLYVVDKDKVQVHIFD
CEEEEECCCCEEEEECCCCCEEEEEECCCCCEEECCCCCEEECCEEEEEECCCEEEEEEC
GDGNTLETISKPEWKKPRNIKILENQIFLTDELTGIWTYSLLNGDWTQLPKFRDKKGVYR
CCCCEEECCCCCCCCCCCCEEEEECEEEEEECCCEEEEEEEECCCHHHCCCCCCCCCCEE
VLFRPFAANMDGTGSLYFVDFGKHRIDIFSQKNNLLSNLDLKIESIDTSDFPNIHIYTRV
EEEHHHHCCCCCCCCEEEEECCCEEEEEEECCCCCHHCCCEEEEECCCCCCCCEEEEEEE
KNRGGKELVGIDRLSFRIFENDNMTPLFSLANKNKVNEKLNLAIIYENSESLKKGKLSLE
CCCCCCEEEEEEEEEEEEEECCCCCEEEEECCCCCCCCEEEEEEEEECCCCHHHCCCCHH
DGLFPLFRSLHDTDHVAVYRAGKDSQLILRETVSLRDILAKIRDGQPEEKHNFGKASIAA
CCHHHHHHHHCCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHH
LKKLSMEIGPKALVYLVSKEAKEDSFYQYQKSRIVTYAKAHSIPIYVLTTNPNPSYEESW
HHHHHHHCCCCEEEEEEECCCCCCHHHHHHHCEEEEEEECCCCEEEEEECCCCCCHHHHH
SDITSPTNGKYIYLDGEGEERELYKQFRSHLDYRYILSYKTDTNPELINRYIKIGIGVNH
HHCCCCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHEEEEECCCC
RGVKGRDEGGYFVPEPR
CCCCCCCCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA