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The map label for this gene is aspC [C]

Identifier: 183220798

GI number: 183220798

Start: 1467755

End: 1468897

Strand: Reverse

Name: aspC [C]

Synonym: LEPBI_I1409

Alternate gene names: 183220798

Gene position: 1468897-1467755 (Counterclockwise)

Preceding gene: 183220804

Following gene: 183220797

Centisome position: 40.81

GC content: 42.26

Gene sequence:

>1143_bases
TTGACCCGTACCTCCCCAAAAAACCATGATGATTCCATGGAATTTGCCAATAGAATGAATGGGATCGACTCCTCTCCCAT
CCGAAAAGCCTTCGAACTTGCACGTAGCATCCAAAACCCCATCAATCTGAGTATCGGGCAACCCCACTTCCCTTGCCCAC
CTAACATCATCGAAGCGATGAATCGGGCAGCCATGGAAGGGAAAACCTCTTACACACTCACAGCGGGAATTCCTGAGTTA
AAAACCGCGATGGCAGAAAAATACCGTTCCCAAAATCAGATGCAGTATGCACATGAGGATCGAATCCTTGTGACTTCTGG
AATTTCCTCTGCTTTGTTTTTATTATTCAATGCTCTCATCAACGAAGGGGATGAATGCCTTGTGATCTCACCTTATTTTT
TGATGTATCCTGCCATGATCAAATTTTATGGAGGGAAGTTGGTTCCCCTTTCCGAAAACTTTGAAGCCAAAGATTTGGAA
ACTCTGAAAAACAGAAAATTCAAACTCATCATCTTCTCCAATCCATCGAACCCAACAGGCAAAGTGTTTTCGAAAGAACA
ACTCCGTGCTTTGGCAAACCTGGCAGAATCCACAGGAGCCTACCTGATCAGTGATGAAATTTATGAACTCTTTGACTATG
ATGAGAAGTTTTTTTCCATCGGAAGTGAGTATGAAAAAACCATCACTCTCACTGGATTTTCGAAAACATACAATATGACA
GGTCTTAGGCTTGCCACAATCCTTGCAGAAGAAAAGGTCATCCAAGCACTCACCACCTTACAACAGTACACTGTCGTATG
TGCCCCTTCCATCACCCAATGGGCAGGGATCGAAGCACTTAAAACAGACATGACGGCTTATATCCAGGATTATAAAGAAA
AACGCGATTTTGTTTACGAATCCTTAAAAGACTACTACCCCATCCAAAAATCAGGTGGTGCTTTTTATTCTTTTTTTCAA
GTGCCTTGCGATGATGAAGAGTTCATCAAACGTGCTGTCAAAAAAGACCTCATCCTTGTTCCAGGGTTTATCTTCTGTGA
TGCCAAAAATTTTGTGCGACTATCTTTTGCAACCGAGTGGGAAACTTTGAAACGAGGGATGAAGGCCTTACAAGAACTTT
CGAAAGAAAGTGAATCATTTTAG

Upstream 100 bases:

>100_bases
TTTCTGAGTGCGGAAGGACTGGCACTTTCACGCCGGCGATGGTTACAAATTCCATATCCTTCAGATTTCTACTCAATTGT
AGGTTGTAAACCAAATTCTA

Downstream 100 bases:

>100_bases
GAGAATAATGAAAAGAACATGGAATCACTGGTAGAATCAAACTGGTATTTTCTTTCCACCGGACTAGCTTATGTGATTCT
ATTTTTTTTTGCAACTTCCC

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MTRTSPKNHDDSMEFANRMNGIDSSPIRKAFELARSIQNPINLSIGQPHFPCPPNIIEAMNRAAMEGKTSYTLTAGIPEL
KTAMAEKYRSQNQMQYAHEDRILVTSGISSALFLLFNALINEGDECLVISPYFLMYPAMIKFYGGKLVPLSENFEAKDLE
TLKNRKFKLIIFSNPSNPTGKVFSKEQLRALANLAESTGAYLISDEIYELFDYDEKFFSIGSEYEKTITLTGFSKTYNMT
GLRLATILAEEKVIQALTTLQQYTVVCAPSITQWAGIEALKTDMTAYIQDYKEKRDFVYESLKDYYPIQKSGGAFYSFFQ
VPCDDEEFIKRAVKKDLILVPGFIFCDAKNFVRLSFATEWETLKRGMKALQELSKESESF

Sequences:

>Translated_380_residues
MTRTSPKNHDDSMEFANRMNGIDSSPIRKAFELARSIQNPINLSIGQPHFPCPPNIIEAMNRAAMEGKTSYTLTAGIPEL
KTAMAEKYRSQNQMQYAHEDRILVTSGISSALFLLFNALINEGDECLVISPYFLMYPAMIKFYGGKLVPLSENFEAKDLE
TLKNRKFKLIIFSNPSNPTGKVFSKEQLRALANLAESTGAYLISDEIYELFDYDEKFFSIGSEYEKTITLTGFSKTYNMT
GLRLATILAEEKVIQALTTLQQYTVVCAPSITQWAGIEALKTDMTAYIQDYKEKRDFVYESLKDYYPIQKSGGAFYSFFQ
VPCDDEEFIKRAVKKDLILVPGFIFCDAKNFVRLSFATEWETLKRGMKALQELSKESESF
>Mature_379_residues
TRTSPKNHDDSMEFANRMNGIDSSPIRKAFELARSIQNPINLSIGQPHFPCPPNIIEAMNRAAMEGKTSYTLTAGIPELK
TAMAEKYRSQNQMQYAHEDRILVTSGISSALFLLFNALINEGDECLVISPYFLMYPAMIKFYGGKLVPLSENFEAKDLET
LKNRKFKLIIFSNPSNPTGKVFSKEQLRALANLAESTGAYLISDEIYELFDYDEKFFSIGSEYEKTITLTGFSKTYNMTG
LRLATILAEEKVIQALTTLQQYTVVCAPSITQWAGIEALKTDMTAYIQDYKEKRDFVYESLKDYYPIQKSGGAFYSFFQV
PCDDEEFIKRAVKKDLILVPGFIFCDAKNFVRLSFATEWETLKRGMKALQELSKESESF

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=405, Percent_Identity=28.8888888888889, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI169881279, Length=405, Percent_Identity=28.8888888888889, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI56713254, Length=419, Percent_Identity=28.4009546539379, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI56713256, Length=419, Percent_Identity=28.4009546539379, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI4507369, Length=394, Percent_Identity=25.8883248730964, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI169881281, Length=402, Percent_Identity=23.8805970149254, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI1786816, Length=354, Percent_Identity=24.5762711864407, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1788722, Length=361, Percent_Identity=24.9307479224377, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788627, Length=369, Percent_Identity=25.7452574525745, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788332, Length=174, Percent_Identity=28.735632183908, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI48994949, Length=350, Percent_Identity=24, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71994472, Length=391, Percent_Identity=27.3657289002558, Blast_Score=138, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI71994476, Length=391, Percent_Identity=27.3657289002558, Blast_Score=138, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI17567369, Length=272, Percent_Identity=29.0441176470588, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17567663, Length=384, Percent_Identity=24.21875, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6322401, Length=231, Percent_Identity=28.1385281385281, Blast_Score=86, Evalue=8e-18,
Organism=Drosophila melanogaster, GI28573069, Length=338, Percent_Identity=26.6272189349112, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24646114, Length=338, Percent_Identity=26.6272189349112, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI28573067, Length=338, Percent_Identity=26.6272189349112, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI28573065, Length=338, Percent_Identity=26.6272189349112, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI18859735, Length=399, Percent_Identity=24.3107769423559, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43186; Mature: 43055

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRTSPKNHDDSMEFANRMNGIDSSPIRKAFELARSIQNPINLSIGQPHFPCPPNIIEAM
CCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEECCCCCCCCCCCHHHHHH
NRAAMEGKTSYTLTAGIPELKTAMAEKYRSQNQMQYAHEDRILVTSGISSALFLLFNALI
HHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHH
NEGDECLVISPYFLMYPAMIKFYGGKLVPLSENFEAKDLETLKNRKFKLIIFSNPSNPTG
CCCCCEEEECCHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHCCCEEEEEEECCCCCCC
KVFSKEQLRALANLAESTGAYLISDEIYELFDYDEKFFSIGSEYEKTITLTGFSKTYNMT
CCCCHHHHHHHHHHHHHCCCEEEHHHHHHHHCCHHHHHHCCCCCCCEEEEEECCCCCCCC
GLRLATILAEEKVIQALTTLQQYTVVCAPSITQWAGIEALKTDMTAYIQDYKEKRDFVYE
HHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
SLKDYYPIQKSGGAFYSFFQVPCDDEEFIKRAVKKDLILVPGFIFCDAKNFVRLSFATEW
HHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCEEEECCEEEECCCCEEEEEEHHHH
ETLKRGMKALQELSKESESF
HHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TRTSPKNHDDSMEFANRMNGIDSSPIRKAFELARSIQNPINLSIGQPHFPCPPNIIEAM
CCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEECCCCCCCCCCCHHHHHH
NRAAMEGKTSYTLTAGIPELKTAMAEKYRSQNQMQYAHEDRILVTSGISSALFLLFNALI
HHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHH
NEGDECLVISPYFLMYPAMIKFYGGKLVPLSENFEAKDLETLKNRKFKLIIFSNPSNPTG
CCCCCEEEECCHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHCCCEEEEEEECCCCCCC
KVFSKEQLRALANLAESTGAYLISDEIYELFDYDEKFFSIGSEYEKTITLTGFSKTYNMT
CCCCHHHHHHHHHHHHHCCCEEEHHHHHHHHCCHHHHHHCCCCCCCEEEEEECCCCCCCC
GLRLATILAEEKVIQALTTLQQYTVVCAPSITQWAGIEALKTDMTAYIQDYKEKRDFVYE
HHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
SLKDYYPIQKSGGAFYSFFQVPCDDEEFIKRAVKKDLILVPGFIFCDAKNFVRLSFATEW
HHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCEEEECCEEEECCCCEEEEEEHHHH
ETLKRGMKALQELSKESESF
HHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]