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The map label for this gene is arcB [H]

Identifier: 183220472

GI number: 183220472

Start: 1109790

End: 1112213

Strand: Reverse

Name: arcB [H]

Synonym: LEPBI_I1069

Alternate gene names: 183220472

Gene position: 1112213-1109790 (Counterclockwise)

Preceding gene: 183220473

Following gene: 183220471

Centisome position: 30.9

GC content: 33.46

Gene sequence:

>2424_bases
TTGTCGTCAAATCTTGCAAAGCTTGTGAAACAAATCATCCTCAATATTTTGTTTTCGTTTCTGATCTTCAGTTTCTTTGG
CTGTATTCAAAAGCCAAATCCACCAATGGCAAAATTTGGAATTTTAGATAGTAGGGATTGGAATTTTGATTTATATGGAA
ATGTACCTTTAAACGGAGAGTGGGAAATCCATTGGAAACAATGGGAACCAAAAGAAGAACAAAAACCCTCTTATACAAAA
ATCCCTGGTAACTGGACTGATTCCCTGGGAAATAAATTGCCGAATGGTTACGCAACACTCCGCTTAAAAATATTGGTAAA
AGAAAATACAAAATCTTTTTATCTACAGAATGGTGTGACTAGAAATGCATTTCGAATTCAAGTTGGAAATGAAACGGTCT
ATGAATCAGGAAAAATAGGTTTTGATTCTGAATCGGAAATTTCAAACATCAATATTCAAACTGTTTCTCTGCCTCAAGTT
GAAAAAGGATTCATTGATCTTAGAATACAAGTTTCTTGTTTTCACTATCATGTATGTGGAGTTGCCACACCGTATTTACT
TGGAACTCATGATGGTATCAATAAATCATTTTTTGAAGCGACTAGCCGGGATATTTTAGTATTTTCATCACTGGGAACTC
TCGCTTTTTTCCATTTTGTTTTATTTCTATTTTGGCGTGATGAAAAAACACATTTATACTTTTCTTTTGTTTGTTTGCTC
GCATCCATTCGAATTTTAAGCATTGGAGAAACACGTCTCATATACAATTATATACCGATGGGTATGTATGAATTTATGGT
GAGGGTGAATGGAATTTCCTTTACCTTATTGTACCTATCTTTTGTTCGTTATGTGAAAGAAGTGTATCCAGATAAAAAGT
ATCAATATTTTTATCAAATGAATTATATTGCCGCAGTAATTCTTATCTTTGGAATTCCTTTTCCGACACAAATTTATTCC
AAAATCCAATCTTACCATTTAATCCTTTCACTACTTGGTTTGTTCACTCTTCTTTATCCCATCATTCATGGTGTGATGGT
AAAAAAACCAGGAGCAAGGTTCTTTTTATTTTCCCTCGTTTCCACGATGTTACTTTTTTCATTGGATATTTTGACTGAGT
TTGCTAAAAAAGGAACCGCTTATTTAGGTCAATATGGATTCTTAGTATTTGGTTTGTCTCAAGCATTGTTTATCGCTGAT
CGTATGATCCAAAATTTCAAAAACAAAGAAAAACTAAAACAGGAAAAGGAGTTAGCTCTCGCTGAAGTCAGATTCAAATC
CGCATTTTTATCCACAATGAGTCATGAAATTCGAACGCCTATGAATGGAATTTTGGGTATGACCCAAATGTTTGGTCAAA
CAAGTCTAACAGATGAACAAAAAGAATATTTAAGTTTGATTCAATTTAGTGGAGAAAATTTATTATTACTCGTCAATGAT
ATTTTGGATTTAACGAAACTTGAGGCAGGGAAATTTGAATTACGTTTAGAAACAATTGTATTGTCGAAATTTTTAAACGA
TATGGTACAATTGTTTCGATCCAAAATTAACACACAATATGTGAATCTTGAGTTAGTGACAAATACAGACCTTCCAAAAC
ATATCATCACTGACCAAAGGAGATTCAATCAAATAATTTCGAATTTATTGGGGAATGCAATCAAGTTCACTGAAACCGGA
ACCATATCATTGATCGTTTGGTCAGATCCAATCGATTCAAAAAAATGCAAACTCAATCTCCAAATCAAAGATACTGGTAT
TGGTATTCCCAATGAAAAATTGAACGATTTATTCCAACCATTTTTACAAATTCATTCCCATCTATCAGGAAAAACAAACG
GGACAGGACTTGGTCTTACCATCACAAAAAAAATTGTAGAAGAAATGTCAGGAAAAATCTCCGTTTTATCGGAGTTAGGA
AAAGGATCGGTATTTCATGTAGAGATCCCAGTTTCAGTCAGTAATGAGGAAATTCCAACAAGCGACAGTTTACCGAATCA
AAGTTTTCTAAAATCCGACAATTGGGAAAAAAATTTAGCGGAGAAATACCCTGCGAAAATTCTGATCGCTGATGATGATT
CCATCAATTTAAAAGTATCTAAAATGTTTCTAAAAAAATTGGGTTATGTTGCACTCATTGCAGAAAATGGGGAAAAAACT
CTCGAAGTAGTGGAAAAAGAAAATCCAGATTTGATTTTACTGGATGTTCAAATGCCTGATATCGATGGAATCCAAGTCAC
AAAACAAATCAGAAAGAACAAAAATTTGAAACGGCAACCAATTATCATTGCTTTGACCGCAAATGTGATGGAAGAAGAAA
AGGAAAATTGTCTTTCCTCTGGAATGGATGATTTTATGACCAAACCACTGCTCATGCAGGATTTGGTTTATATGATTAAA
AAATGGTCAAAAGGATTCGATTGA

Upstream 100 bases:

>100_bases
AGGATACATCCGAAAACCGAATCTAATTTCTTTCCTTATTTTGGACTTTCAGAATAAAATCAAAGCTTTTCTAAACTAGA
GTGCAATGCTAGGATGTTCT

Downstream 100 bases:

>100_bases
ATTGATGGAACATTCATTAGTTGTGGGAGCAACTTCGGATATCGGAATTTGGGTAGTGGATGCATTGGCAAAACGAGGAC
ATTCCCTTTCCTTAACTGGT

Product: putative two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 807; Mature: 806

Protein sequence:

>807_residues
MSSNLAKLVKQIILNILFSFLIFSFFGCIQKPNPPMAKFGILDSRDWNFDLYGNVPLNGEWEIHWKQWEPKEEQKPSYTK
IPGNWTDSLGNKLPNGYATLRLKILVKENTKSFYLQNGVTRNAFRIQVGNETVYESGKIGFDSESEISNINIQTVSLPQV
EKGFIDLRIQVSCFHYHVCGVATPYLLGTHDGINKSFFEATSRDILVFSSLGTLAFFHFVLFLFWRDEKTHLYFSFVCLL
ASIRILSIGETRLIYNYIPMGMYEFMVRVNGISFTLLYLSFVRYVKEVYPDKKYQYFYQMNYIAAVILIFGIPFPTQIYS
KIQSYHLILSLLGLFTLLYPIIHGVMVKKPGARFFLFSLVSTMLLFSLDILTEFAKKGTAYLGQYGFLVFGLSQALFIAD
RMIQNFKNKEKLKQEKELALAEVRFKSAFLSTMSHEIRTPMNGILGMTQMFGQTSLTDEQKEYLSLIQFSGENLLLLVND
ILDLTKLEAGKFELRLETIVLSKFLNDMVQLFRSKINTQYVNLELVTNTDLPKHIITDQRRFNQIISNLLGNAIKFTETG
TISLIVWSDPIDSKKCKLNLQIKDTGIGIPNEKLNDLFQPFLQIHSHLSGKTNGTGLGLTITKKIVEEMSGKISVLSELG
KGSVFHVEIPVSVSNEEIPTSDSLPNQSFLKSDNWEKNLAEKYPAKILIADDDSINLKVSKMFLKKLGYVALIAENGEKT
LEVVEKENPDLILLDVQMPDIDGIQVTKQIRKNKNLKRQPIIIALTANVMEEEKENCLSSGMDDFMTKPLLMQDLVYMIK
KWSKGFD

Sequences:

>Translated_807_residues
MSSNLAKLVKQIILNILFSFLIFSFFGCIQKPNPPMAKFGILDSRDWNFDLYGNVPLNGEWEIHWKQWEPKEEQKPSYTK
IPGNWTDSLGNKLPNGYATLRLKILVKENTKSFYLQNGVTRNAFRIQVGNETVYESGKIGFDSESEISNINIQTVSLPQV
EKGFIDLRIQVSCFHYHVCGVATPYLLGTHDGINKSFFEATSRDILVFSSLGTLAFFHFVLFLFWRDEKTHLYFSFVCLL
ASIRILSIGETRLIYNYIPMGMYEFMVRVNGISFTLLYLSFVRYVKEVYPDKKYQYFYQMNYIAAVILIFGIPFPTQIYS
KIQSYHLILSLLGLFTLLYPIIHGVMVKKPGARFFLFSLVSTMLLFSLDILTEFAKKGTAYLGQYGFLVFGLSQALFIAD
RMIQNFKNKEKLKQEKELALAEVRFKSAFLSTMSHEIRTPMNGILGMTQMFGQTSLTDEQKEYLSLIQFSGENLLLLVND
ILDLTKLEAGKFELRLETIVLSKFLNDMVQLFRSKINTQYVNLELVTNTDLPKHIITDQRRFNQIISNLLGNAIKFTETG
TISLIVWSDPIDSKKCKLNLQIKDTGIGIPNEKLNDLFQPFLQIHSHLSGKTNGTGLGLTITKKIVEEMSGKISVLSELG
KGSVFHVEIPVSVSNEEIPTSDSLPNQSFLKSDNWEKNLAEKYPAKILIADDDSINLKVSKMFLKKLGYVALIAENGEKT
LEVVEKENPDLILLDVQMPDIDGIQVTKQIRKNKNLKRQPIIIALTANVMEEEKENCLSSGMDDFMTKPLLMQDLVYMIK
KWSKGFD
>Mature_806_residues
SSNLAKLVKQIILNILFSFLIFSFFGCIQKPNPPMAKFGILDSRDWNFDLYGNVPLNGEWEIHWKQWEPKEEQKPSYTKI
PGNWTDSLGNKLPNGYATLRLKILVKENTKSFYLQNGVTRNAFRIQVGNETVYESGKIGFDSESEISNINIQTVSLPQVE
KGFIDLRIQVSCFHYHVCGVATPYLLGTHDGINKSFFEATSRDILVFSSLGTLAFFHFVLFLFWRDEKTHLYFSFVCLLA
SIRILSIGETRLIYNYIPMGMYEFMVRVNGISFTLLYLSFVRYVKEVYPDKKYQYFYQMNYIAAVILIFGIPFPTQIYSK
IQSYHLILSLLGLFTLLYPIIHGVMVKKPGARFFLFSLVSTMLLFSLDILTEFAKKGTAYLGQYGFLVFGLSQALFIADR
MIQNFKNKEKLKQEKELALAEVRFKSAFLSTMSHEIRTPMNGILGMTQMFGQTSLTDEQKEYLSLIQFSGENLLLLVNDI
LDLTKLEAGKFELRLETIVLSKFLNDMVQLFRSKINTQYVNLELVTNTDLPKHIITDQRRFNQIISNLLGNAIKFTETGT
ISLIVWSDPIDSKKCKLNLQIKDTGIGIPNEKLNDLFQPFLQIHSHLSGKTNGTGLGLTITKKIVEEMSGKISVLSELGK
GSVFHVEIPVSVSNEEIPTSDSLPNQSFLKSDNWEKNLAEKYPAKILIADDDSINLKVSKMFLKKLGYVALIAENGEKTL
EVVEKENPDLILLDVQMPDIDGIQVTKQIRKNKNLKRQPIIIALTANVMEEEKENCLSSGMDDFMTKPLLMQDLVYMIKK
WSKGFD

Specific function: Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His- 717 and

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=384, Percent_Identity=35.15625, Blast_Score=233, Evalue=5e-62,
Organism=Escherichia coli, GI1789149, Length=243, Percent_Identity=43.2098765432099, Blast_Score=196, Evalue=7e-51,
Organism=Escherichia coli, GI1788713, Length=385, Percent_Identity=33.2467532467532, Blast_Score=193, Evalue=4e-50,
Organism=Escherichia coli, GI87081816, Length=383, Percent_Identity=31.5926892950392, Blast_Score=186, Evalue=7e-48,
Organism=Escherichia coli, GI145693157, Length=245, Percent_Identity=35.1020408163265, Blast_Score=146, Evalue=7e-36,
Organism=Escherichia coli, GI1790436, Length=250, Percent_Identity=28, Blast_Score=102, Evalue=9e-23,
Organism=Escherichia coli, GI87082128, Length=235, Percent_Identity=26.8085106382979, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1786912, Length=246, Percent_Identity=25.2032520325203, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1786600, Length=229, Percent_Identity=25.3275109170306, Blast_Score=77, Evalue=6e-15,
Organism=Escherichia coli, GI1788393, Length=230, Percent_Identity=25.6521739130435, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1788549, Length=260, Percent_Identity=23.4615384615385, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1786783, Length=229, Percent_Identity=25.3275109170306, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1787894, Length=232, Percent_Identity=23.2758620689655, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1786599, Length=115, Percent_Identity=31.304347826087, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1787229, Length=117, Percent_Identity=28.2051282051282, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=142, Percent_Identity=27.4647887323944, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322044, Length=127, Percent_Identity=32.2834645669291, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR014409
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 92180; Mature: 92048

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSNLAKLVKQIILNILFSFLIFSFFGCIQKPNPPMAKFGILDSRDWNFDLYGNVPLNGE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCEEEEECCCCCCE
WEIHWKQWEPKEEQKPSYTKIPGNWTDSLGNKLPNGYATLRLKILVKENTKSFYLQNGVT
EEEEECCCCCCCCCCCCCEECCCCCHHHHHCCCCCCEEEEEEEEEEECCCCEEEEECCCC
RNAFRIQVGNETVYESGKIGFDSESEISNINIQTVSLPQVEKGFIDLRIQVSCFHYHVCG
CCEEEEEECCCEEECCCCCCCCCCCCCCEEEEEEEECCCHHCCEEEEEEEEEEEEEEEHH
VATPYLLGTHDGINKSFFEATSRDILVFSSLGTLAFFHFVLFLFWRDEKTHLYFSFVCLL
HCCCCEEECCCCCCHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
ASIRILSIGETRLIYNYIPMGMYEFMVRVNGISFTLLYLSFVRYVKEVYPDKKYQYFYQM
HHHHHEECCCCEEEEHHHCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHH
NYIAAVILIFGIPFPTQIYSKIQSYHLILSLLGLFTLLYPIIHGVMVKKPGARFFLFSLV
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCHHHHHHHH
STMLLFSLDILTEFAKKGTAYLGQYGFLVFGLSQALFIADRMIQNFKNKEKLKQEKELAL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
AEVRFKSAFLSTMSHEIRTPMNGILGMTQMFGQTSLTDEQKEYLSLIQFSGENLLLLVND
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEHHH
ILDLTKLEAGKFELRLETIVLSKFLNDMVQLFRSKINTQYVNLELVTNTDLPKHIITDQR
HHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCHHHHHHHH
RFNQIISNLLGNAIKFTETGTISLIVWSDPIDSKKCKLNLQIKDTGIGIPNEKLNDLFQP
HHHHHHHHHHCCCEEEECCCEEEEEEECCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHH
FLQIHSHLSGKTNGTGLGLTITKKIVEEMSGKISVLSELGKGSVFHVEIPVSVSNEEIPT
HHHHHHHCCCCCCCCEEEHHHHHHHHHHHCCHHHHHHHHCCCCEEEEEEEEEECCCCCCC
SDSLPNQSFLKSDNWEKNLAEKYPAKILIADDDSINLKVSKMFLKKLGYVALIAENGEKT
CCCCCCCHHHCCCCCHHHHHHHCCCEEEEECCCCCEEEHHHHHHHHCCEEEEEECCCCHH
LEVVEKENPDLILLDVQMPDIDGIQVTKQIRKNKNLKRQPIIIALTANVMEEEKENCLSS
HHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHHC
GMDDFMTKPLLMQDLVYMIKKWSKGFD
CHHHHHCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SSNLAKLVKQIILNILFSFLIFSFFGCIQKPNPPMAKFGILDSRDWNFDLYGNVPLNGE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCEEEEECCCCCCE
WEIHWKQWEPKEEQKPSYTKIPGNWTDSLGNKLPNGYATLRLKILVKENTKSFYLQNGVT
EEEEECCCCCCCCCCCCCEECCCCCHHHHHCCCCCCEEEEEEEEEEECCCCEEEEECCCC
RNAFRIQVGNETVYESGKIGFDSESEISNINIQTVSLPQVEKGFIDLRIQVSCFHYHVCG
CCEEEEEECCCEEECCCCCCCCCCCCCCEEEEEEEECCCHHCCEEEEEEEEEEEEEEEHH
VATPYLLGTHDGINKSFFEATSRDILVFSSLGTLAFFHFVLFLFWRDEKTHLYFSFVCLL
HCCCCEEECCCCCCHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
ASIRILSIGETRLIYNYIPMGMYEFMVRVNGISFTLLYLSFVRYVKEVYPDKKYQYFYQM
HHHHHEECCCCEEEEHHHCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHH
NYIAAVILIFGIPFPTQIYSKIQSYHLILSLLGLFTLLYPIIHGVMVKKPGARFFLFSLV
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCHHHHHHHH
STMLLFSLDILTEFAKKGTAYLGQYGFLVFGLSQALFIADRMIQNFKNKEKLKQEKELAL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
AEVRFKSAFLSTMSHEIRTPMNGILGMTQMFGQTSLTDEQKEYLSLIQFSGENLLLLVND
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEHHH
ILDLTKLEAGKFELRLETIVLSKFLNDMVQLFRSKINTQYVNLELVTNTDLPKHIITDQR
HHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCHHHHHHHH
RFNQIISNLLGNAIKFTETGTISLIVWSDPIDSKKCKLNLQIKDTGIGIPNEKLNDLFQP
HHHHHHHHHHCCCEEEECCCEEEEEEECCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHH
FLQIHSHLSGKTNGTGLGLTITKKIVEEMSGKISVLSELGKGSVFHVEIPVSVSNEEIPT
HHHHHHHCCCCCCCCEEEHHHHHHHHHHHCCHHHHHHHHCCCCEEEEEEEEEECCCCCCC
SDSLPNQSFLKSDNWEKNLAEKYPAKILIADDDSINLKVSKMFLKKLGYVALIAENGEKT
CCCCCCCHHHCCCCCHHHHHHHCCCEEEEECCCCCEEEHHHHHHHHCCEEEEEECCCCHH
LEVVEKENPDLILLDVQMPDIDGIQVTKQIRKNKNLKRQPIIIALTANVMEEEKENCLSS
HHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHHC
GMDDFMTKPLLMQDLVYMIKKWSKGFD
CHHHHHCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]