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The map label for this gene is galE [H]

Identifier: 183219774

GI number: 183219774

Start: 350803

End: 351771

Strand: Reverse

Name: galE [H]

Synonym: LEPBI_I0351

Alternate gene names: 183219774

Gene position: 351771-350803 (Counterclockwise)

Preceding gene: 183219775

Following gene: 183219768

Centisome position: 9.77

GC content: 39.53

Gene sequence:

>969_bases
ATGAGAGTTCTCGTTACCGGGGGAGCCGGATATATCGGAAGTCATATTGTCCTCGAACTTATGGAACTAGGACATGAAAT
CATCATTGTAGATGATATGGAAAAAGGAAACGAAGCCAATTTGTTTCCCGAAAATGAATTCATCAAAGGCGAAATCCAAG
ATCCTGAAATCTTAAAAAAAGCCTTCGCTAAAAAAGTGGATGCTGTCTTCCATTTTGCCGCATGGAAAGCAGCAGGGGAA
TCGATGACCGATCCTCTCAAATACACAATGAACAATTTAAATGGCACCTTCACATTGTTAAACGCAATGATCCAATATGG
ATGCCAGTACATTGTATTTTCATCGTCTGCGGCAGTCTATGGAGCTCCAAAGTACTTACCCATTGATGAAAACCATCCCT
TACAACCAGAGAACTATTATGGTTATACCAAACTTTGTATTGAAGAAAATTTGGAGTGGTTTGATAAACTAAAAGGTTTA
AAGTCCGCAAGGCTAAGATACTTCAATGCCGCAGGGTATGATCCCAAAGGGAGGATCAAGGGAATCGAAAAAACTCCTGC
GAATTTACTCCCCATCATTATGGAAGCGGCATCCGGAATTCGAAATGGATTTCAAATTTATGGAAACGACTATGAAACAG
AAGATGGTACTTGTGTTCGCGACTACATCCACGTTTCGGATTTAGCGAAGGCACATGTTTTAGCATTAAACTACATCATG
GCAAATAATCAAAGTTTAACGGTAAATCTAGGATCCGAATCTGGTTACTCAGTAAAAGAAATGACAGACTTATCAGAAAA
AGTTGTAGGAAAACCAATCTCTCACGTAACTGGTCCTAGGCGACTCGGAGATCCAGCGAAGTTACTTGCTTCTTCCAAAA
AAGCAAGGGAACTTCTCAATTGGAAACCAATTTATAGTGATGCAGAAACCCTACTTTCTAGTATGTGGAATCTCTACAAA
AACTTATAA

Upstream 100 bases:

>100_bases
CAAACCCTGCACCAGAAGTGCAAAAGGTAATCGAATTCTTCGAAACAAGCAAACGTGGTGTTGTGGACCACCGTTTTGTT
TCTGGTGGATCCGACGAAGA

Downstream 100 bases:

>100_bases
ATTAGCAGAACCTATCTTTTCACATTCCGGGTTGATGGATCTAACAAAATCCAAGGCCCGGTTGTCGAGCACATCAGCAC
CTAAAAAACTTCCTTCCAGC

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MRVLVTGGAGYIGSHIVLELMELGHEIIIVDDMEKGNEANLFPENEFIKGEIQDPEILKKAFAKKVDAVFHFAAWKAAGE
SMTDPLKYTMNNLNGTFTLLNAMIQYGCQYIVFSSSAAVYGAPKYLPIDENHPLQPENYYGYTKLCIEENLEWFDKLKGL
KSARLRYFNAAGYDPKGRIKGIEKTPANLLPIIMEAASGIRNGFQIYGNDYETEDGTCVRDYIHVSDLAKAHVLALNYIM
ANNQSLTVNLGSESGYSVKEMTDLSEKVVGKPISHVTGPRRLGDPAKLLASSKKARELLNWKPIYSDAETLLSSMWNLYK
NL

Sequences:

>Translated_322_residues
MRVLVTGGAGYIGSHIVLELMELGHEIIIVDDMEKGNEANLFPENEFIKGEIQDPEILKKAFAKKVDAVFHFAAWKAAGE
SMTDPLKYTMNNLNGTFTLLNAMIQYGCQYIVFSSSAAVYGAPKYLPIDENHPLQPENYYGYTKLCIEENLEWFDKLKGL
KSARLRYFNAAGYDPKGRIKGIEKTPANLLPIIMEAASGIRNGFQIYGNDYETEDGTCVRDYIHVSDLAKAHVLALNYIM
ANNQSLTVNLGSESGYSVKEMTDLSEKVVGKPISHVTGPRRLGDPAKLLASSKKARELLNWKPIYSDAETLLSSMWNLYK
NL
>Mature_322_residues
MRVLVTGGAGYIGSHIVLELMELGHEIIIVDDMEKGNEANLFPENEFIKGEIQDPEILKKAFAKKVDAVFHFAAWKAAGE
SMTDPLKYTMNNLNGTFTLLNAMIQYGCQYIVFSSSAAVYGAPKYLPIDENHPLQPENYYGYTKLCIEENLEWFDKLKGL
KSARLRYFNAAGYDPKGRIKGIEKTPANLLPIIMEAASGIRNGFQIYGNDYETEDGTCVRDYIHVSDLAKAHVLALNYIM
ANNQSLTVNLGSESGYSVKEMTDLSEKVVGKPISHVTGPRRLGDPAKLLASSKKARELLNWKPIYSDAETLLSSMWNLYK
NL

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=337, Percent_Identity=40.9495548961424, Blast_Score=221, Evalue=8e-58,
Organism=Homo sapiens, GI56118217, Length=337, Percent_Identity=40.9495548961424, Blast_Score=221, Evalue=8e-58,
Organism=Homo sapiens, GI189083684, Length=337, Percent_Identity=40.9495548961424, Blast_Score=221, Evalue=8e-58,
Organism=Homo sapiens, GI42516563, Length=331, Percent_Identity=28.0966767371601, Blast_Score=104, Evalue=9e-23,
Organism=Homo sapiens, GI7657641, Length=282, Percent_Identity=26.9503546099291, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI239745448, Length=287, Percent_Identity=26.4808362369338, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI310132178, Length=290, Percent_Identity=27.2413793103448, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI310113012, Length=290, Percent_Identity=27.2413793103448, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1786974, Length=315, Percent_Identity=40.9523809523809, Blast_Score=217, Evalue=6e-58,
Organism=Escherichia coli, GI1790049, Length=277, Percent_Identity=26.3537906137184, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71982035, Length=347, Percent_Identity=37.7521613832853, Blast_Score=193, Evalue=8e-50,
Organism=Caenorhabditis elegans, GI71982038, Length=349, Percent_Identity=37.5358166189112, Blast_Score=192, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17539532, Length=337, Percent_Identity=26.4094955489614, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6319493, Length=322, Percent_Identity=41.9254658385093, Blast_Score=207, Evalue=2e-54,
Organism=Drosophila melanogaster, GI19923002, Length=319, Percent_Identity=42.0062695924765, Blast_Score=209, Evalue=3e-54,
Organism=Drosophila melanogaster, GI21356223, Length=325, Percent_Identity=28.6153846153846, Blast_Score=110, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 35951; Mature: 35951

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLVTGGAGYIGSHIVLELMELGHEIIIVDDMEKGNEANLFPENEFIKGEIQDPEILKK
CEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEECCCCCHHHHHH
AFAKKVDAVFHFAAWKAAGESMTDPLKYTMNNLNGTFTLLNAMIQYGCQYIVFSSSAAVY
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCEEEEEECCCEEE
GAPKYLPIDENHPLQPENYYGYTKLCIEENLEWFDKLKGLKSARLRYFNAAGYDPKGRIK
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHCHHHHHHHCCHHHHHHHEEECCCCCCCCCCC
GIEKTPANLLPIIMEAASGIRNGFQIYGNDYETEDGTCVRDYIHVSDLAKAHVLALNYIM
CCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEE
ANNQSLTVNLGSESGYSVKEMTDLSEKVVGKPISHVTGPRRLGDPAKLLASSKKARELLN
ECCCEEEEEECCCCCCCHHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHCCHHHHHHHC
WKPIYSDAETLLSSMWNLYKNL
CCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRVLVTGGAGYIGSHIVLELMELGHEIIIVDDMEKGNEANLFPENEFIKGEIQDPEILKK
CEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEECCCCCHHHHHH
AFAKKVDAVFHFAAWKAAGESMTDPLKYTMNNLNGTFTLLNAMIQYGCQYIVFSSSAAVY
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCEEEEEECCCEEE
GAPKYLPIDENHPLQPENYYGYTKLCIEENLEWFDKLKGLKSARLRYFNAAGYDPKGRIK
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHCHHHHHHHCCHHHHHHHEEECCCCCCCCCCC
GIEKTPANLLPIIMEAASGIRNGFQIYGNDYETEDGTCVRDYIHVSDLAKAHVLALNYIM
CCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEE
ANNQSLTVNLGSESGYSVKEMTDLSEKVVGKPISHVTGPRRLGDPAKLLASSKKARELLN
ECCCEEEEEECCCCCCCHHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHCCHHHHHHHC
WKPIYSDAETLLSSMWNLYKNL
CCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9603808 [H]