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The map label for this gene is gpsA

Identifier: 183219768

GI number: 183219768

Start: 344782

End: 345783

Strand: Reverse

Name: gpsA

Synonym: LEPBI_I0345

Alternate gene names: 183219768

Gene position: 345783-344782 (Counterclockwise)

Preceding gene: 183219774

Following gene: 183219758

Centisome position: 9.61

GC content: 45.51

Gene sequence:

>1002_bases
ATGAAGATTGGAATCATTGGCGCTGGAAGTTTTGGCACTGCACTAGGTAGTATTTTGGCAGACAAGGGTTATGACGTTAC
CCTTTGGACAAGAAGTGAGGAACAAGCTCGTTCCATCAATGAAAACCATATGAATTCCAAACATATGCCTGATTTGGTCT
TACCCGATCGTTTGAAAGCGAGTACTGACCTCATCCAAGTGGTCAAAGACAAGGATATGATCGTCTCTGCTCCCCCTAGC
CATGCCCTTTCTGGGATCTTAAAGGAAATCAAAGACCATATCCCACCCAAGGTTCCCATTGTTTCCGCTTCTAAAGGGAT
CGAAAATGAAAGTTTACGTCTTGTTTCTGAAATTTTTGAATCAGAATTACCTGGGCAATTCCATTCGCAACTCTCCTATC
TCTCTGGACCTAGTTTTGCCAAAGAGATGGTGAAACGAGTTCCAACCATTGTCTCCATCGCTTCCAAAAACGAAGCCACC
GCCAAACGAGTGCAAGAGATCTTTAGCTTTACCTATTTTCGTACGTATTGGACTCCTGATGTGGTTGGTGTGGAAGTGGG
TGGTGCCTTAAAGAATGTGATCGCCATTGCCGCAGGGGTTGCCGATGGACTTGGGTTTGGTCAAAATACAAGGGCGGCCC
TCATCACACGCGGGTTAAACGAAATCACAAGGATGGGAATCAAAATGGGTGCCGATCCAATGACATTCCTCGGACCTTCC
GGGATGGGGGATCTTGTCCTCACTTGTTGTGGGGAAGCATCGAGAAACCGAACCGTAGGATTTCGATTGGGGAAAGGGGA
ATCTTTAAAAGAAATTTTGTCCTCGATGAATGAAGTGGCAGAAGGAGTGAAAACCACTCTCTCCACCAAAAACCTAGCAG
ATAAATTGGGAGTAGAGATGGCCATCACCCAAGAAGTGTATCATATGTTATACGAAGATAAAGACCCAAAAGAAGTGGTG
AGAGCCCTCATGAGTCGTGACCTCAAACGAGAAGGAGTTTAA

Upstream 100 bases:

>100_bases
AAGAGATTCAGTGGGTTGAAACGGAAGAGATCCGTCAAAAGCATATTTTAATTTTATTTTCTATTGCCTTTTTGGAAAGC
AGATTTAGAATACTGAACTC

Downstream 100 bases:

>100_bases
ACCAATCGAATCAGTAGTATGATATAAGATACAATCTGGATCATATAAAATGTGAACCGAATGTTCACAGCAAGGACATT
TGTAGCGACCAAATGAGTGA

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MKIGIIGAGSFGTALGSILADKGYDVTLWTRSEEQARSINENHMNSKHMPDLVLPDRLKASTDLIQVVKDKDMIVSAPPS
HALSGILKEIKDHIPPKVPIVSASKGIENESLRLVSEIFESELPGQFHSQLSYLSGPSFAKEMVKRVPTIVSIASKNEAT
AKRVQEIFSFTYFRTYWTPDVVGVEVGGALKNVIAIAAGVADGLGFGQNTRAALITRGLNEITRMGIKMGADPMTFLGPS
GMGDLVLTCCGEASRNRTVGFRLGKGESLKEILSSMNEVAEGVKTTLSTKNLADKLGVEMAITQEVYHMLYEDKDPKEVV
RALMSRDLKREGV

Sequences:

>Translated_333_residues
MKIGIIGAGSFGTALGSILADKGYDVTLWTRSEEQARSINENHMNSKHMPDLVLPDRLKASTDLIQVVKDKDMIVSAPPS
HALSGILKEIKDHIPPKVPIVSASKGIENESLRLVSEIFESELPGQFHSQLSYLSGPSFAKEMVKRVPTIVSIASKNEAT
AKRVQEIFSFTYFRTYWTPDVVGVEVGGALKNVIAIAAGVADGLGFGQNTRAALITRGLNEITRMGIKMGADPMTFLGPS
GMGDLVLTCCGEASRNRTVGFRLGKGESLKEILSSMNEVAEGVKTTLSTKNLADKLGVEMAITQEVYHMLYEDKDPKEVV
RALMSRDLKREGV
>Mature_333_residues
MKIGIIGAGSFGTALGSILADKGYDVTLWTRSEEQARSINENHMNSKHMPDLVLPDRLKASTDLIQVVKDKDMIVSAPPS
HALSGILKEIKDHIPPKVPIVSASKGIENESLRLVSEIFESELPGQFHSQLSYLSGPSFAKEMVKRVPTIVSIASKNEAT
AKRVQEIFSFTYFRTYWTPDVVGVEVGGALKNVIAIAAGVADGLGFGQNTRAALITRGLNEITRMGIKMGADPMTFLGPS
GMGDLVLTCCGEASRNRTVGFRLGKGESLKEILSSMNEVAEGVKTTLSTKNLADKLGVEMAITQEVYHMLYEDKDPKEVV
RALMSRDLKREGV

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI33695088, Length=351, Percent_Identity=31.9088319088319, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI24307999, Length=352, Percent_Identity=29.8295454545455, Blast_Score=135, Evalue=7e-32,
Organism=Escherichia coli, GI1790037, Length=328, Percent_Identity=41.7682926829268, Blast_Score=272, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI32564399, Length=346, Percent_Identity=30.3468208092486, Blast_Score=130, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI193210136, Length=355, Percent_Identity=29.5774647887324, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI32564403, Length=355, Percent_Identity=29.5774647887324, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17507425, Length=282, Percent_Identity=28.7234042553192, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI193210134, Length=343, Percent_Identity=27.1137026239067, Blast_Score=92, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6320181, Length=366, Percent_Identity=30.0546448087432, Blast_Score=134, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6324513, Length=347, Percent_Identity=27.9538904899135, Blast_Score=130, Evalue=2e-31,
Organism=Drosophila melanogaster, GI22026922, Length=352, Percent_Identity=28.6931818181818, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI17136204, Length=329, Percent_Identity=28.2674772036474, Blast_Score=107, Evalue=9e-24,
Organism=Drosophila melanogaster, GI17136202, Length=329, Percent_Identity=28.2674772036474, Blast_Score=107, Evalue=9e-24,
Organism=Drosophila melanogaster, GI17136200, Length=329, Percent_Identity=28.2674772036474, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI45551945, Length=263, Percent_Identity=30.4182509505703, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI281362270, Length=263, Percent_Identity=30.4182509505703, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24648969, Length=214, Percent_Identity=30.8411214953271, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_LEPBA (B0SAV3)

Other databases:

- EMBL:   CP000777
- RefSeq:   YP_001961458.1
- ProteinModelPortal:   B0SAV3
- SMR:   B0SAV3
- GeneID:   6388444
- GenomeReviews:   CP000777_GR
- KEGG:   lbf:LBF_0334
- HOGENOM:   HBG586392
- OMA:   ASVIMEF
- ProtClustDB:   PRK00094
- BioCyc:   LBIF355278:LBF_0334-MONOMER
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 36125; Mature: 36125

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 191-191 BINDING 105-105 BINDING 105-105 BINDING 140-140 BINDING 255-255 BINDING 281-281

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGIIGAGSFGTALGSILADKGYDVTLWTRSEEQARSINENHMNSKHMPDLVLPDRLKA
CEEEEEECCHHHHHHHHHHHCCCCEEEEEECCHHHHHHCCHHCCCCCCCCCCCCCHHHHH
STDLIQVVKDKDMIVSAPPSHALSGILKEIKDHIPPKVPIVSASKGIENESLRLVSEIFE
HHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHH
SELPGQFHSQLSYLSGPSFAKEMVKRVPTIVSIASKNEATAKRVQEIFSFTYFRTYWTPD
HCCCHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCC
VVGVEVGGALKNVIAIAAGVADGLGFGQNTRAALITRGLNEITRMGIKMGADPMTFLGPS
EEEEEHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHCCCC
GMGDLVLTCCGEASRNRTVGFRLGKGESLKEILSSMNEVAEGVKTTLSTKNLADKLGVEM
CCHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
AITQEVYHMLYEDKDPKEVVRALMSRDLKREGV
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIGIIGAGSFGTALGSILADKGYDVTLWTRSEEQARSINENHMNSKHMPDLVLPDRLKA
CEEEEEECCHHHHHHHHHHHCCCCEEEEEECCHHHHHHCCHHCCCCCCCCCCCCCHHHHH
STDLIQVVKDKDMIVSAPPSHALSGILKEIKDHIPPKVPIVSASKGIENESLRLVSEIFE
HHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHH
SELPGQFHSQLSYLSGPSFAKEMVKRVPTIVSIASKNEATAKRVQEIFSFTYFRTYWTPD
HCCCHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCC
VVGVEVGGALKNVIAIAAGVADGLGFGQNTRAALITRGLNEITRMGIKMGADPMTFLGPS
EEEEEHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHCCCC
GMGDLVLTCCGEASRNRTVGFRLGKGESLKEILSSMNEVAEGVKTTLSTKNLADKLGVEM
CCHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
AITQEVYHMLYEDKDPKEVVRALMSRDLKREGV
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA