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The map label for this gene is nudL [H]

Identifier: 183219596

GI number: 183219596

Start: 166221

End: 166847

Strand: Reverse

Name: nudL [H]

Synonym: LEPBI_I0171

Alternate gene names: 183219596

Gene position: 166847-166221 (Counterclockwise)

Preceding gene: 183219597

Following gene: 183219595

Centisome position: 4.64

GC content: 43.22

Gene sequence:

>627_bases
ATGTTACCCTACCAGTCCTTTGTAAATCAACTTTCAAGGGACTTCGATGCAATCCCTGATACATCGGAAACAAAATCCGG
TGTCATCTTTCCTCTGTTTGGTTCCAAAGAAACTGCAGAGGGGATCATTCTCACAGAACGTGCCAAACACTTAAAAAGTC
ACCCAGGACAAATCTCCTTTCCTGGGGGAGTGATGGAAACATCTGATCCCAATTTGCTTGTCACTGCCCTTCGGGAATGG
GAAGAAGAAATGGGCGTGGAACGAACTGCGCTCGATATTTTAGGCAAATTACAAGGATTACACACTCGCACTGGGTTTCA
CATCACCCCTTTTTTGGCAAAGTATGATGGTGATTTTACTTTTTCCCAAAACAAAGACGAAGTGGAAAGGATCATCCTCT
TACCATTTTCTGATCTTTGGACGAGACCCTTTTATGCGATCCAAATCCCAGGTCGAGAACCAAACCATTTTGCCTATTAT
TTTGATTTACCAGATGGTCTTTTATGGGGTGCCACGTGTGAGATGATCTTACGATTCTTAAAAGAACACTCTCCATTTGA
TCGATCTCCCCAAATTGTGCAACCAAACCTCACAAAACCGCCATATTTGGACCCCAAATCCCTCTAA

Upstream 100 bases:

>100_bases
TTGATTCGATGATCAACCGATTGGTTGCCATCCGTTCCAAAGAAGCATTTGTAGCCAAACGTAGGAAAAAACAAAACCAA
AACTCGAAAGACGAGGGTTG

Downstream 100 bases:

>100_bases
GGGGAAATGGATTTTTCGCCGATCTTGTACAAGTGCGAAAACAAATGGAATCTCAGATGGTGGGGTGTGGGAAATTCCCA
CTCAAAATTATTTTTCTTCT

Product: putative hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MLPYQSFVNQLSRDFDAIPDTSETKSGVIFPLFGSKETAEGIILTERAKHLKSHPGQISFPGGVMETSDPNLLVTALREW
EEEMGVERTALDILGKLQGLHTRTGFHITPFLAKYDGDFTFSQNKDEVERIILLPFSDLWTRPFYAIQIPGREPNHFAYY
FDLPDGLLWGATCEMILRFLKEHSPFDRSPQIVQPNLTKPPYLDPKSL

Sequences:

>Translated_208_residues
MLPYQSFVNQLSRDFDAIPDTSETKSGVIFPLFGSKETAEGIILTERAKHLKSHPGQISFPGGVMETSDPNLLVTALREW
EEEMGVERTALDILGKLQGLHTRTGFHITPFLAKYDGDFTFSQNKDEVERIILLPFSDLWTRPFYAIQIPGREPNHFAYY
FDLPDGLLWGATCEMILRFLKEHSPFDRSPQIVQPNLTKPPYLDPKSL
>Mature_208_residues
MLPYQSFVNQLSRDFDAIPDTSETKSGVIFPLFGSKETAEGIILTERAKHLKSHPGQISFPGGVMETSDPNLLVTALREW
EEEMGVERTALDILGKLQGLHTRTGFHITPFLAKYDGDFTFSQNKDEVERIILLPFSDLWTRPFYAIQIPGREPNHFAYY
FDLPDGLLWGATCEMILRFLKEHSPFDRSPQIVQPNLTKPPYLDPKSL

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI157785656, Length=151, Percent_Identity=29.8013245033113, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1788115, Length=156, Percent_Identity=27.5641025641026, Blast_Score=67, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17510677, Length=128, Percent_Identity=35.15625, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17536993, Length=117, Percent_Identity=32.4786324786325, Blast_Score=63, Evalue=8e-11,
Organism=Drosophila melanogaster, GI18859683, Length=118, Percent_Identity=34.7457627118644, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 23701; Mature: 23701

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPYQSFVNQLSRDFDAIPDTSETKSGVIFPLFGSKETAEGIILTERAKHLKSHPGQISF
CCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCEEEHHHHHHHHCCCCEEEC
PGGVMETSDPNLLVTALREWEEEMGVERTALDILGKLQGLHTRTGFHITPFLAKYDGDFT
CCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEEEHHHEECCCCEE
FSQNKDEVERIILLPFSDLWTRPFYAIQIPGREPNHFAYYFDLPDGLLWGATCEMILRFL
ECCCHHCEEEEEECCCHHHHCCCEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHH
KEHSPFDRSPQIVQPNLTKPPYLDPKSL
HHCCCCCCCCCEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MLPYQSFVNQLSRDFDAIPDTSETKSGVIFPLFGSKETAEGIILTERAKHLKSHPGQISF
CCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCEEEHHHHHHHHCCCCEEEC
PGGVMETSDPNLLVTALREWEEEMGVERTALDILGKLQGLHTRTGFHITPFLAKYDGDFT
CCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEEEHHHEECCCCEE
FSQNKDEVERIILLPFSDLWTRPFYAIQIPGREPNHFAYYFDLPDGLLWGATCEMILRFL
ECCCHHCEEEEEECCCHHHHCCCEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHH
KEHSPFDRSPQIVQPNLTKPPYLDPKSL
HHCCCCCCCCCEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA