| Definition | Clostridium perfringens str. 13, complete genome. |
|---|---|
| Accession | NC_003366 |
| Length | 3,031,430 |
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The map label for this gene is hetN [H]
Identifier: 18311563
GI number: 18311563
Start: 2956508
End: 2957281
Strand: Reverse
Name: hetN [H]
Synonym: CPE2581
Alternate gene names: 18311563
Gene position: 2957281-2956508 (Counterclockwise)
Preceding gene: 161485638
Following gene: 18311562
Centisome position: 97.55
GC content: 27.78
Gene sequence:
>774_bases ATGAAGAAAACAGTTTTAATAACAGGGGCTACTAGTGGAATTGGATATGAATTTTCAAAAATATTTATGGAAAACAATTA TGATGTAATATTAGTAGGAAGAAATTTAGAAAAATTAATAGAATTAGAAGATTTTTCGAAGAAAAAATATGTAAGGGCTT ACATATATAAATTTGATTTGAGTTTAAGTGAAAACATAGATTTTTTATATAAAAAAATTAAAACTGAAGTAGGAAAAGTA GATATATTAATAAATAATGCTGGTATAGGATTTAATGGAGAATTTAATGAAATAGATTGGCAAAAGCAATTAGATATAAT AAATGTAAATATTATAAGTTTAACCAAATTAACTAAGCTTATTTTAAAAGATATGATAAATGAAAAGGAAGGGAAAATCT TAAATGTTTCCTCTACTGGGGCCTATCAACCAGGTCCATTAATTTCAGTTTATTATGCTAGTAAAGCATATGTTTTATCG TTTTCTGAGGCTTTAAGAGAAGAGGTTAAAGATAAGGGAATTAATGTGGTTACTCTTTGCCCTGGAGCTACTAAGACGAA TTTTTCTAAGAGAGCTGGAAAGGGAGATTTAGATGTGGCAATGAGTGCAGAAGAAGTAGCAGAGTGTGGCTATAAGGCTT TGATGAACAATAAGGCAATATGTATTCCTGGGATTATGAATAAGGTATTAGTATTTTTATCTAAAGTGTCTCCCACAACT TTAAATGCAAAGATAGTAAAGAAAATACAAAATAAGGCTATAAGTAAAAAATAA
Upstream 100 bases:
>100_bases AAAGGTTTTTTAAATAAAGGTTTACAGAAAAAACTTGACATATTAGCAAAAAACATAATAAATGTTTTATTAAGGATTTA TTTATAAGAAGGGAATTTTT
Downstream 100 bases:
>100_bases TTGAGAATAATAAGCTTATAAATAATTAAATTTAAAATAAAGTTTTTAAGGAGGAAATTATTTATGAGCAATGAAAAATT ATTCCCAACAACATTTCCAG
Product: oxidoreductase, short-chain dehydrogenase/reductase family
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 257; Mature: 257
Protein sequence:
>257_residues MKKTVLITGATSGIGYEFSKIFMENNYDVILVGRNLEKLIELEDFSKKKYVRAYIYKFDLSLSENIDFLYKKIKTEVGKV DILINNAGIGFNGEFNEIDWQKQLDIINVNIISLTKLTKLILKDMINEKEGKILNVSSTGAYQPGPLISVYYASKAYVLS FSEALREEVKDKGINVVTLCPGATKTNFSKRAGKGDLDVAMSAEEVAECGYKALMNNKAICIPGIMNKVLVFLSKVSPTT LNAKIVKKIQNKAISKK
Sequences:
>Translated_257_residues MKKTVLITGATSGIGYEFSKIFMENNYDVILVGRNLEKLIELEDFSKKKYVRAYIYKFDLSLSENIDFLYKKIKTEVGKV DILINNAGIGFNGEFNEIDWQKQLDIINVNIISLTKLTKLILKDMINEKEGKILNVSSTGAYQPGPLISVYYASKAYVLS FSEALREEVKDKGINVVTLCPGATKTNFSKRAGKGDLDVAMSAEEVAECGYKALMNNKAICIPGIMNKVLVFLSKVSPTT LNAKIVKKIQNKAISKK >Mature_257_residues MKKTVLITGATSGIGYEFSKIFMENNYDVILVGRNLEKLIELEDFSKKKYVRAYIYKFDLSLSENIDFLYKKIKTEVGKV DILINNAGIGFNGEFNEIDWQKQLDIINVNIISLTKLTKLILKDMINEKEGKILNVSSTGAYQPGPLISVYYASKAYVLS FSEALREEVKDKGINVVTLCPGATKTNFSKRAGKGDLDVAMSAEEVAECGYKALMNNKAICIPGIMNKVLVFLSKVSPTT LNAKIVKKIQNKAISKK
Specific function: May be involved in repressing heterocyst differentiation and may be essential for preventing all vegetative cells from differentiating [H]
COG id: COG0300
COG function: function code R; Short-chain dehydrogenases of various substrate specificities
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI20149619, Length=198, Percent_Identity=34.8484848484849, Blast_Score=103, Evalue=1e-22, Organism=Homo sapiens, GI7705855, Length=195, Percent_Identity=34.3589743589744, Blast_Score=99, Evalue=4e-21, Organism=Homo sapiens, GI4557649, Length=205, Percent_Identity=36.0975609756098, Blast_Score=98, Evalue=6e-21, Organism=Homo sapiens, GI226371731, Length=192, Percent_Identity=32.2916666666667, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI210032110, Length=250, Percent_Identity=29.2, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI109715829, Length=215, Percent_Identity=27.906976744186, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI31542939, Length=191, Percent_Identity=30.8900523560209, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI142976729, Length=257, Percent_Identity=29.9610894941634, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI157739938, Length=184, Percent_Identity=30.9782608695652, Blast_Score=82, Evalue=7e-16, Organism=Homo sapiens, GI40254992, Length=191, Percent_Identity=25.6544502617801, Blast_Score=78, Evalue=6e-15, Organism=Homo sapiens, GI7706318, Length=201, Percent_Identity=28.8557213930348, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI32483357, Length=192, Percent_Identity=26.5625, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI224922801, Length=167, Percent_Identity=30.5389221556886, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI7657478, Length=191, Percent_Identity=27.7486910994764, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI226371733, Length=187, Percent_Identity=26.7379679144385, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI33667109, Length=213, Percent_Identity=29.5774647887324, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI210032112, Length=203, Percent_Identity=28.0788177339901, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI5031737, Length=198, Percent_Identity=29.2929292929293, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI4504503, Length=200, Percent_Identity=29, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI4503817, Length=217, Percent_Identity=26.2672811059908, Blast_Score=66, Evalue=2e-11, Organism=Homo sapiens, GI22507405, Length=190, Percent_Identity=28.9473684210526, Blast_Score=65, Evalue=6e-11, Organism=Escherichia coli, GI1787820, Length=219, Percent_Identity=31.0502283105023, Blast_Score=98, Evalue=5e-22, Organism=Escherichia coli, GI87082100, Length=191, Percent_Identity=30.3664921465969, Blast_Score=89, Evalue=4e-19, Organism=Escherichia coli, GI1787335, Length=190, Percent_Identity=28.4210526315789, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI1790717, Length=188, Percent_Identity=26.5957446808511, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1786701, Length=193, Percent_Identity=28.4974093264249, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1788459, Length=209, Percent_Identity=27.2727272727273, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1789208, Length=193, Percent_Identity=29.0155440414508, Blast_Score=72, Evalue=4e-14, Organism=Escherichia coli, GI87082160, Length=195, Percent_Identity=27.6923076923077, Blast_Score=65, Evalue=4e-12, Organism=Escherichia coli, GI1787526, Length=194, Percent_Identity=27.319587628866, Blast_Score=65, Evalue=5e-12, Organism=Caenorhabditis elegans, GI71994604, Length=194, Percent_Identity=32.9896907216495, Blast_Score=97, Evalue=9e-21, Organism=Caenorhabditis elegans, GI71994600, Length=193, Percent_Identity=31.6062176165803, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17562906, Length=229, Percent_Identity=27.0742358078603, Blast_Score=81, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17562908, Length=202, Percent_Identity=29.2079207920792, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI25152911, Length=194, Percent_Identity=31.4432989690722, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17562910, Length=214, Percent_Identity=32.7102803738318, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17560220, Length=246, Percent_Identity=28.0487804878049, Blast_Score=77, Evalue=7e-15, Organism=Caenorhabditis elegans, GI17562904, Length=231, Percent_Identity=26.4069264069264, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI193204405, Length=225, Percent_Identity=28.4444444444444, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17563726, Length=251, Percent_Identity=30.6772908366534, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI193203115, Length=245, Percent_Identity=30.2040816326531, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI193203117, Length=245, Percent_Identity=30.2040816326531, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17560332, Length=195, Percent_Identity=27.1794871794872, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17551412, Length=252, Percent_Identity=26.5873015873016, Blast_Score=71, Evalue=4e-13, Organism=Caenorhabditis elegans, GI212646214, Length=192, Percent_Identity=30.7291666666667, Blast_Score=70, Evalue=7e-13, Organism=Caenorhabditis elegans, GI17538486, Length=235, Percent_Identity=28.936170212766, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI17560176, Length=195, Percent_Identity=30.7692307692308, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI71997402, Length=256, Percent_Identity=28.125, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17559962, Length=249, Percent_Identity=27.710843373494, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17538480, Length=249, Percent_Identity=26.1044176706827, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI72001658, Length=221, Percent_Identity=29.8642533936652, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI72000259, Length=252, Percent_Identity=26.984126984127, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17562990, Length=232, Percent_Identity=26.2931034482759, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17559964, Length=207, Percent_Identity=29.4685990338164, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI115534694, Length=189, Percent_Identity=28.042328042328, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17560150, Length=234, Percent_Identity=27.3504273504274, Blast_Score=66, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17558990, Length=211, Percent_Identity=27.0142180094787, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17558992, Length=227, Percent_Identity=27.3127753303965, Blast_Score=65, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17570069, Length=257, Percent_Identity=27.6264591439689, Blast_Score=65, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17561402, Length=216, Percent_Identity=26.3888888888889, Blast_Score=65, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17559104, Length=252, Percent_Identity=24.2063492063492, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17508895, Length=200, Percent_Identity=26, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17544670, Length=204, Percent_Identity=29.4117647058824, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI17532177, Length=232, Percent_Identity=28.0172413793103, Blast_Score=65, Evalue=5e-11, Organism=Saccharomyces cerevisiae, GI6323882, Length=194, Percent_Identity=32.9896907216495, Blast_Score=98, Evalue=1e-21, Organism=Saccharomyces cerevisiae, GI6320089, Length=193, Percent_Identity=29.5336787564767, Blast_Score=72, Evalue=6e-14, Organism=Saccharomyces cerevisiae, GI6322227, Length=199, Percent_Identity=26.6331658291457, Blast_Score=68, Evalue=1e-12, Organism=Saccharomyces cerevisiae, GI6322067, Length=194, Percent_Identity=27.8350515463918, Blast_Score=65, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6319635, Length=188, Percent_Identity=27.6595744680851, Blast_Score=63, Evalue=4e-11, Organism=Drosophila melanogaster, GI24640442, Length=198, Percent_Identity=35.3535353535354, Blast_Score=105, Evalue=3e-23, Organism=Drosophila melanogaster, GI21358495, Length=252, Percent_Identity=29.3650793650794, Blast_Score=94, Evalue=1e-19, Organism=Drosophila melanogaster, GI24584744, Length=200, Percent_Identity=32, Blast_Score=92, Evalue=3e-19, Organism=Drosophila melanogaster, GI28574402, Length=200, Percent_Identity=32, Blast_Score=92, Evalue=3e-19, Organism=Drosophila melanogaster, GI161076933, Length=199, Percent_Identity=31.1557788944724, Blast_Score=92, Evalue=4e-19, Organism=Drosophila melanogaster, GI24584748, Length=199, Percent_Identity=31.1557788944724, Blast_Score=92, Evalue=4e-19, Organism=Drosophila melanogaster, GI21357041, Length=192, Percent_Identity=31.25, Blast_Score=91, Evalue=9e-19, Organism=Drosophila melanogaster, GI24644339, Length=192, Percent_Identity=31.25, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI23397609, Length=193, Percent_Identity=30.0518134715026, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI24651139, Length=223, Percent_Identity=29.1479820627803, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI28571526, Length=192, Percent_Identity=30.2083333333333, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI24584752, Length=201, Percent_Identity=32.8358208955224, Blast_Score=86, Evalue=3e-17, Organism=Drosophila melanogaster, GI28571387, Length=223, Percent_Identity=26.9058295964126, Blast_Score=84, Evalue=9e-17, Organism=Drosophila melanogaster, GI221331218, Length=198, Percent_Identity=31.8181818181818, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI24665243, Length=198, Percent_Identity=31.8181818181818, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI24665247, Length=192, Percent_Identity=31.7708333333333, Blast_Score=78, Evalue=6e-15, Organism=Drosophila melanogaster, GI221331216, Length=199, Percent_Identity=31.6582914572864, Blast_Score=78, Evalue=7e-15, Organism=Drosophila melanogaster, GI116007236, Length=213, Percent_Identity=25.3521126760563, Blast_Score=74, Evalue=9e-14, Organism=Drosophila melanogaster, GI24641388, Length=224, Percent_Identity=28.125, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI24649181, Length=234, Percent_Identity=28.2051282051282, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24580925, Length=260, Percent_Identity=24.6153846153846, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI21355319, Length=192, Percent_Identity=28.125, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI21355631, Length=250, Percent_Identity=27.6, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI116007238, Length=175, Percent_Identity=24.5714285714286, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI281364494, Length=196, Percent_Identity=26.530612244898, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI24639444, Length=184, Percent_Identity=29.8913043478261, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI24665264, Length=153, Percent_Identity=26.797385620915, Blast_Score=64, Evalue=8e-11,
Paralogues:
None
Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.-.-.- [C]
Molecular weight: Translated: 28633; Mature: 28633
Theoretical pI: Translated: 9.75; Mature: 9.75
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 3.5 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 3.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKKTVLITGATSGIGYEFSKIFMENNYDVILVGRNLEKLIELEDFSKKKYVRAYIYKFDL CCCEEEEEECCCCCCCEEEEEEEECCCEEEEECCCHHHHHHHHHCCHHHHEEEEEEEEEC SLSENIDFLYKKIKTEVGKVDILINNAGIGFNGEFNEIDWQKQLDIINVNIISLTKLTKL CCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHCCEEEEEEEEHHHHHHHH ILKDMINEKEGKILNVSSTGAYQPGPLISVYYASKAYVLSFSEALREEVKDKGINVVTLC HHHHHHCCCCCCEEEEECCCCCCCCCEEEEEECCCEEEEEHHHHHHHHHHHCCCCEEEEC PGATKTNFSKRAGKGDLDVAMSAEEVAECGYKALMNNKAICIPGIMNKVLVFLSKVSPTT CCCCCCCCHHHCCCCCCEEEECHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCC LNAKIVKKIQNKAISKK CHHHHHHHHHHHHCCCC >Mature Secondary Structure MKKTVLITGATSGIGYEFSKIFMENNYDVILVGRNLEKLIELEDFSKKKYVRAYIYKFDL CCCEEEEEECCCCCCCEEEEEEEECCCEEEEECCCHHHHHHHHHCCHHHHEEEEEEEEEC SLSENIDFLYKKIKTEVGKVDILINNAGIGFNGEFNEIDWQKQLDIINVNIISLTKLTKL CCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHCCEEEEEEEEHHHHHHHH ILKDMINEKEGKILNVSSTGAYQPGPLISVYYASKAYVLSFSEALREEVKDKGINVVTLC HHHHHHCCCCCCEEEEECCCCCCCCCEEEEEECCCEEEEEHHHHHHHHHHHCCCCEEEEC PGATKTNFSKRAGKGDLDVAMSAEEVAECGYKALMNNKAICIPGIMNKVLVFLSKVSPTT CCCCCCCCHHHCCCCCCEEEECHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCC LNAKIVKKIQNKAISKK CHHHHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8157596; 11759840 [H]