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The map label for this gene is dsbD [H]

Identifier: 18311519

GI number: 18311519

Start: 2905948

End: 2906640

Strand: Reverse

Name: dsbD [H]

Synonym: CPE2537

Alternate gene names: 18311519

Gene position: 2906640-2905948 (Counterclockwise)

Preceding gene: 18311520

Following gene: 18311518

Centisome position: 95.88

GC content: 28.86

Gene sequence:

>693_bases
ATGGAATTTTTAGCTTATTTTAATATTAGCATATCTAATAATATATTTTTAGCCATAATACTATCATTCTTTGCAGGAGT
AGTAGCCTCTTTTAGTACATGTACCCTTTCATCTATTCCATTATTAATAGGATATGTTCAAGGTAGTGAGGTTAAGGATA
ATAAGAAAGCATTTAAGTATTCACTGATATTTTCAATTGGACTTGGAATAACATTTACTGTAATAGGTTTACTTACAGCC
TTAATAGGAAAAGCTTTTTTAGGTGCAGGGAAGTTTTGGTATATAATATTGGCTTTTATTATGATAGGATCAGGGCTACA
AGTTCTTGATGTAATAAATTTATTTGGAGATAAAAAAGATGCTTGTAAAATCACTAAAAAAAGAGAGGGAATTTTAGATG
CCTTCTTTTTAGGAATATTAAGTGGAATATTAGCATCTCCTTGTGCAACACCTATAATGGCAGCAATAATAGCCTTTATA
GCTGCTAGTGGTAACTTAGTAATAGGAATGATAATGCTTTTAATGTATTCATTAGGTCATAGTGTTTTAATAATTTTAGC
TGGAACATCCTTTGGATTAGTTGAGAAAATAGCCTACTCTGAAAACGGTAAAAAGATAGGAAGAGTATTAAAAAATATAT
TAGGAACAATTATAATATTAGTTGGATTATACTTATTTTATCTTGGAGTATAG

Upstream 100 bases:

>100_bases
GTTTTTAGATAAAGAAGGTAATAAATTCTATGTTCATCAAGGGCTTATGAGAAAGAATAATATAGAAACCATTTTAAATT
CTTTGGGGGTTAAATAGAAT

Downstream 100 bases:

>100_bases
AAAATATGTAAACCAAATATACAGAAAGTGTTAAATTAAAATGAACTCAAGCAAAACTTATACTAATTTTGATATGATAA
TTATTAATATAAATTTTGAT

Product: hypothetical protein

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MEFLAYFNISISNNIFLAIILSFFAGVVASFSTCTLSSIPLLIGYVQGSEVKDNKKAFKYSLIFSIGLGITFTVIGLLTA
LIGKAFLGAGKFWYIILAFIMIGSGLQVLDVINLFGDKKDACKITKKREGILDAFFLGILSGILASPCATPIMAAIIAFI
AASGNLVIGMIMLLMYSLGHSVLIILAGTSFGLVEKIAYSENGKKIGRVLKNILGTIIILVGLYLFYLGV

Sequences:

>Translated_230_residues
MEFLAYFNISISNNIFLAIILSFFAGVVASFSTCTLSSIPLLIGYVQGSEVKDNKKAFKYSLIFSIGLGITFTVIGLLTA
LIGKAFLGAGKFWYIILAFIMIGSGLQVLDVINLFGDKKDACKITKKREGILDAFFLGILSGILASPCATPIMAAIIAFI
AASGNLVIGMIMLLMYSLGHSVLIILAGTSFGLVEKIAYSENGKKIGRVLKNILGTIIILVGLYLFYLGV
>Mature_230_residues
MEFLAYFNISISNNIFLAIILSFFAGVVASFSTCTLSSIPLLIGYVQGSEVKDNKKAFKYSLIFSIGLGITFTVIGLLTA
LIGKAFLGAGKFWYIILAFIMIGSGLQVLDVINLFGDKKDACKITKKREGILDAFFLGILSGILASPCATPIMAAIIAFI
AASGNLVIGMIMLLMYSLGHSVLIILAGTSFGLVEKIAYSENGKKIGRVLKNILGTIIILVGLYLFYLGV

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG0785

COG function: function code O; Cytochrome c biogenesis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=170, Percent_Identity=27.0588235294118, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 24618; Mature: 24618

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFLAYFNISISNNIFLAIILSFFAGVVASFSTCTLSSIPLLIGYVQGSEVKDNKKAFKY
CCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHH
SLIFSIGLGITFTVIGLLTALIGKAFLGAGKFWYIILAFIMIGSGLQVLDVINLFGDKKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCHH
ACKITKKREGILDAFFLGILSGILASPCATPIMAAIIAFIAASGNLVIGMIMLLMYSLGH
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
SVLIILAGTSFGLVEKIAYSENGKKIGRVLKNILGTIIILVGLYLFYLGV
CEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEFLAYFNISISNNIFLAIILSFFAGVVASFSTCTLSSIPLLIGYVQGSEVKDNKKAFKY
CCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHH
SLIFSIGLGITFTVIGLLTALIGKAFLGAGKFWYIILAFIMIGSGLQVLDVINLFGDKKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCHH
ACKITKKREGILDAFFLGILSGILASPCATPIMAAIIAFIAASGNLVIGMIMLLMYSLGH
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
SVLIILAGTSFGLVEKIAYSENGKKIGRVLKNILGTIIILVGLYLFYLGV
CEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA