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The map label for this gene is add [H]

Identifier: 18311488

GI number: 18311488

Start: 2869991

End: 2870989

Strand: Reverse

Name: add [H]

Synonym: CPE2506

Alternate gene names: 18311488

Gene position: 2870989-2869991 (Counterclockwise)

Preceding gene: 18311489

Following gene: 18311487

Centisome position: 94.71

GC content: 29.53

Gene sequence:

>999_bases
ATGAACTTATTAAATTTACCAAAGATAGAATTACATTGTCATCTAGATGGATCCTTAAGAGTGGAGACTGCTATTGAATT
AGCTAAAAAAGAAGGAGTTAAGCTAGATAGCTATGAATATGATAAGGTAAAAGAATTACTAGTTATTCCTAAAGAATGCA
ATTCATTAGAAGATTATTTAAATAGATTTGCTCTTCCAGTAAAACTGTTACAAAGAGCTGAGAACTTAGAAAGAGTTGCC
TTTGAACTTATGGAAGATGCAAGCAAGGAAAATGTGAAGTACATAGAAATAAGATTTGCTCCATTATTGCATTTAGAAAA
GGGGATGACTCAAAAAGAAGTAATAGAGAGTGTAATAAAGGGAATACGAAAAGCTGAAGAGCTTTATGACATAAAAGGTA
ATTTAATATTATCTTGTTTAAGACATCATTCTATAGATAGTGTATATGAGGTAATTGAAGAGGGGAAAAACTTCATAGGA
AAAGGTGTTGTTGCCATAGACTTAGCTGGTGGTGAATTAGAAGGTTTTGTTAAACCTTATGAAGAAGTAATGAAATTAGC
AAGAGAATCAGGTTTTAGAGTTACAATACACGCTGGTGAAACTGGGTATGGTAAAAATGTTAGAGATGCCATAGAGCTTC
TAGGTGCAGAGAGAATAGGTCATGGATTATTTATATTTAATGATGAAGAGGCTTATAATTTAGTAAAAGAAAAAGGCGTA
ACATTAGAAATGTGCCCTAAGAGTAATATAGACACAAAGGGTGTGAATAAATATGAGGATCATCCTATTTATAAATATCA
TAAAGATAATATAAGAGTTAATTTAAGTACAGATAACAGAACAGTTTCTAATATAAATCTTACTGAAGAATTTGAAAATG
TACATAAGACATTTAATATAGATTTTGAAGATTATAAAAAGATTTATTTAAATAGTGTGGAAGCTTCCTTCTGTTCAGAA
GAGTTAAAGGAAAAATTAAAATTATCCATAATTATATAA

Upstream 100 bases:

>100_bases
AGAATTTTTTTTTGAACCTTTTTTAGGATATATAAATTCTTTATTCAATATTAGAAATTTTAGTTTTAATATAAATATTT
AATTCGGGGAGGAAATATAA

Downstream 100 bases:

>100_bases
ATTCAAAATAATCCACAGGCAAATAGAACTTAATTTACCTGTGGATTATTTTTTAATTCAACAACTGTGGATATTTTTCA
AAAAATTATTCTGTGGATAA

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MNLLNLPKIELHCHLDGSLRVETAIELAKKEGVKLDSYEYDKVKELLVIPKECNSLEDYLNRFALPVKLLQRAENLERVA
FELMEDASKENVKYIEIRFAPLLHLEKGMTQKEVIESVIKGIRKAEELYDIKGNLILSCLRHHSIDSVYEVIEEGKNFIG
KGVVAIDLAGGELEGFVKPYEEVMKLARESGFRVTIHAGETGYGKNVRDAIELLGAERIGHGLFIFNDEEAYNLVKEKGV
TLEMCPKSNIDTKGVNKYEDHPIYKYHKDNIRVNLSTDNRTVSNINLTEEFENVHKTFNIDFEDYKKIYLNSVEASFCSE
ELKEKLKLSIII

Sequences:

>Translated_332_residues
MNLLNLPKIELHCHLDGSLRVETAIELAKKEGVKLDSYEYDKVKELLVIPKECNSLEDYLNRFALPVKLLQRAENLERVA
FELMEDASKENVKYIEIRFAPLLHLEKGMTQKEVIESVIKGIRKAEELYDIKGNLILSCLRHHSIDSVYEVIEEGKNFIG
KGVVAIDLAGGELEGFVKPYEEVMKLARESGFRVTIHAGETGYGKNVRDAIELLGAERIGHGLFIFNDEEAYNLVKEKGV
TLEMCPKSNIDTKGVNKYEDHPIYKYHKDNIRVNLSTDNRTVSNINLTEEFENVHKTFNIDFEDYKKIYLNSVEASFCSE
ELKEKLKLSIII
>Mature_332_residues
MNLLNLPKIELHCHLDGSLRVETAIELAKKEGVKLDSYEYDKVKELLVIPKECNSLEDYLNRFALPVKLLQRAENLERVA
FELMEDASKENVKYIEIRFAPLLHLEKGMTQKEVIESVIKGIRKAEELYDIKGNLILSCLRHHSIDSVYEVIEEGKNFIG
KGVVAIDLAGGELEGFVKPYEEVMKLARESGFRVTIHAGETGYGKNVRDAIELLGAERIGHGLFIFNDEEAYNLVKEKGV
TLEMCPKSNIDTKGVNKYEDHPIYKYHKDNIRVNLSTDNRTVSNINLTEEFENVHKTFNIDFEDYKKIYLNSVEASFCSE
ELKEKLKLSIII

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=341, Percent_Identity=30.4985337243402, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI226693318, Length=337, Percent_Identity=25.2225519287834, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI61175224, Length=230, Percent_Identity=27.8260869565217, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1787910, Length=328, Percent_Identity=29.5731707317073, Blast_Score=157, Evalue=7e-40,
Organism=Caenorhabditis elegans, GI17538512, Length=337, Percent_Identity=34.7181008902077, Blast_Score=164, Evalue=8e-41,
Organism=Caenorhabditis elegans, GI32565969, Length=337, Percent_Identity=34.7181008902077, Blast_Score=164, Evalue=9e-41,
Organism=Caenorhabditis elegans, GI115537133, Length=333, Percent_Identity=24.3243243243243, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6324188, Length=330, Percent_Identity=26.969696969697, Blast_Score=124, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24645260, Length=328, Percent_Identity=26.5243902439024, Blast_Score=107, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 38015; Mature: 38015

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLLNLPKIELHCHLDGSLRVETAIELAKKEGVKLDSYEYDKVKELLVIPKECNSLEDYL
CCCCCCCCEEEEEECCCCEEHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHCCHHHHHH
NRFALPVKLLQRAENLERVAFELMEDASKENVKYIEIRFAPLLHLEKGMTQKEVIESVIK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHCCCHHHHHHHHHH
GIRKAEELYDIKGNLILSCLRHHSIDSVYEVIEEGKNFIGKGVVAIDLAGGELEGFVKPY
HHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHCHHHHCCCEEEEEECCCCHHHHHHHH
EEVMKLARESGFRVTIHAGETGYGKNVRDAIELLGAERIGHGLFIFNDEEAYNLVKEKGV
HHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCC
TLEMCPKSNIDTKGVNKYEDHPIYKYHKDNIRVNLSTDNRTVSNINLTEEFENVHKTFNI
EEEECCCCCCCCCCCCCCCCCCCEEEECCCEEEEEECCCEEEEECCHHHHHHHHHHEECC
DFEDYKKIYLNSVEASFCSEELKEKLKLSIII
CHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEC
>Mature Secondary Structure
MNLLNLPKIELHCHLDGSLRVETAIELAKKEGVKLDSYEYDKVKELLVIPKECNSLEDYL
CCCCCCCCEEEEEECCCCEEHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHCCHHHHHH
NRFALPVKLLQRAENLERVAFELMEDASKENVKYIEIRFAPLLHLEKGMTQKEVIESVIK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHCCCHHHHHHHHHH
GIRKAEELYDIKGNLILSCLRHHSIDSVYEVIEEGKNFIGKGVVAIDLAGGELEGFVKPY
HHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHCHHHHCCCEEEEEECCCCHHHHHHHH
EEVMKLARESGFRVTIHAGETGYGKNVRDAIELLGAERIGHGLFIFNDEEAYNLVKEKGV
HHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCC
TLEMCPKSNIDTKGVNKYEDHPIYKYHKDNIRVNLSTDNRTVSNINLTEEFENVHKTFNI
EEEECCCCCCCCCCCCCCCCCCCEEEECCCEEEEEECCCEEEEECCHHHHHHHHHHEECC
DFEDYKKIYLNSVEASFCSEELKEKLKLSIII
CHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA