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The map label for this gene is ltaS1 [H]

Identifier: 18311219

GI number: 18311219

Start: 2558205

End: 2560094

Strand: Direct

Name: ltaS1 [H]

Synonym: CPE2237

Alternate gene names: 18311219

Gene position: 2558205-2560094 (Clockwise)

Preceding gene: 18311216

Following gene: 18311226

Centisome position: 84.39

GC content: 27.04

Gene sequence:

>1890_bases
ATGCAAGAAAAAGTTAAATTAAATAACGGGCTTTCTAAATTTAAGGAGTCTCTTAATAAAAATGCTTTAATAAGACTAGG
TTTTTACATATTTACTCTTATAGCCATAGTTTTAAAAGGAGCACTTTTTTTAGGTTTCTCTTTAAACCAAAACCTTTACA
CACTTAATTTTAGTTTAGGATATAGACAAGCTTCTTATTTTATTAATTATTACATAGCATTTGCAGCAATATTTGTAAGT
ATATGTTTTTTATTTAAAAACAAAGGTAAATTTTTCTCATTAATAATTGTAGATTTATTTATAACCTTAATTACAGTAAT
GGATATTTGGTATTTTAGAGGATTCCAAACAGTTCCATCAGTAATGCTATTAAAACAAACTGCTAACTTAGATAATCTTG
GAGATAGTATTTTTTCAATGGCTAGTCCATATGACTTACTATTCTTCGTAGACTTTATTATTTTAATAATAGCTTTTATA
ATTTTTAGAAAAAGCTTTAAAAACTGTAAGTCTAATTGGAAAGGTACTTTAATTGTTTTACTTGTATCAATTTGTTATAT
AGGCTATGTTCCTTTTAACGTTAATGTATTAAAAAGAGAAAATGTTAAAAATTCATACTTATTTAGTAACTATGATCCAA
CTAACACAGTAGAATACTTCTCACCAATTGGTTATCATATTTTTGATATATATAATGTTTATAAGAATTCTAAACCTTAT
AAAATGACAGCTGATGATGAAGCAAAAATAAAAGAATATTATGATTTCAAAAATGAAAATCTTCCTGATAATGAATTTAA
GGGAATGTTCAAAGGAAAGAACTTAATAGTAATACAAGTTGAGTCCCTTGAAGACTTTGTTATAAATAAAAAAGTAGATG
GACAAGAAATAACTCCAAACATAAATAAGTTATTAAATAATTCAATTTACTTACCTAATATATTTGAACAAGTTAACGAA
GGTACAAGCTCTGATTCTGACTTAATGGTTAATACTTCTATGTTACCATTAAGACAAGGAAGTACTTTCTTTAGAAACCC
AGCTACAACTTATAACTCATTACCTAATATCTTAGAAAAAGATGGCTATAGCACTATTGCTATCCATTCAGATAAAGGTT
CTTTCTGGAACTATGCTCAAGGTTTAAATGGTATAGGTTTTGATAAATTTGTAGATTACTATTCATTTGATCGTGATGAA
AATATAGGTCTTGGATTAAGTGACGGAAGCTACTTTAGACAAATTGAACCAATGATTAAAGAATTAAAACAACCATTCTA
TGCATTTACAGTTACTTTAACAAGCCACGGACCATTTGATTTACCAAAGGAATACCGTGAATTAAAACTTAGCCCTGAAC
TTGATGACAATGTTTTAGGAGGATATTTCCAAAGTATTCATTATACAGATGCTAAAATAGGAATGTTCATAGAATCACTT
AAAAAAGATGGTCTTTTAGATAACACTGTTATTGCAATAGAAGGTGACCACACTGGTCCTCATAAATACTATAACAGTAA
GATAGAATCACTATCTAATCCTGAATCTTGGTGGTTAGACAATGGAAATCATACAGTTCCATTAATTATTTACAATCCAA
GCATTAAGACACCTGTAAAAGATGATGTTTACGGTGGTCAAATAGATATAATGCCAACTCTTTTATATCTATTAGGCATA
GATAATAATGTATATCAAAATACAGCTTTAGGTAGAAATCTATTAAACACTAAGAGATCTTACGCTGTTTTAACTGATAA
AACAATTAAAGGTGAACTTACAGATAAAGAAAAAGAAATAGTAGGAAATGTATTAGATCTATCTGATAAAATGATTAGAG
CTGATTATTTTAAAGATAAAATACCTAATGATAATTCTAAAAATAATTAA

Upstream 100 bases:

>100_bases
TTCTTTTTAAACTTTTTTGTAATAATTCCTTCATACTATGAACATATTGTTTTATGATATAATATTAACAGCTTTGAATA
ATAAAAGAAGGGGTGTTTCA

Downstream 100 bases:

>100_bases
AAAAAAGAGAGCTGATTTTATATCAGCTCCTTTTTATTTTCTAGAGACCTAAAACTAAAAAAACAGTAGATAGTTTTGTT
TTTTACACCAAACTATCTAC

Product: hypothetical protein

Products: NA

Alternate protein names: LTA synthase 1; Polyglycerol phosphate synthase 1 [H]

Number of amino acids: Translated: 629; Mature: 629

Protein sequence:

>629_residues
MQEKVKLNNGLSKFKESLNKNALIRLGFYIFTLIAIVLKGALFLGFSLNQNLYTLNFSLGYRQASYFINYYIAFAAIFVS
ICFLFKNKGKFFSLIIVDLFITLITVMDIWYFRGFQTVPSVMLLKQTANLDNLGDSIFSMASPYDLLFFVDFIILIIAFI
IFRKSFKNCKSNWKGTLIVLLVSICYIGYVPFNVNVLKRENVKNSYLFSNYDPTNTVEYFSPIGYHIFDIYNVYKNSKPY
KMTADDEAKIKEYYDFKNENLPDNEFKGMFKGKNLIVIQVESLEDFVINKKVDGQEITPNINKLLNNSIYLPNIFEQVNE
GTSSDSDLMVNTSMLPLRQGSTFFRNPATTYNSLPNILEKDGYSTIAIHSDKGSFWNYAQGLNGIGFDKFVDYYSFDRDE
NIGLGLSDGSYFRQIEPMIKELKQPFYAFTVTLTSHGPFDLPKEYRELKLSPELDDNVLGGYFQSIHYTDAKIGMFIESL
KKDGLLDNTVIAIEGDHTGPHKYYNSKIESLSNPESWWLDNGNHTVPLIIYNPSIKTPVKDDVYGGQIDIMPTLLYLLGI
DNNVYQNTALGRNLLNTKRSYAVLTDKTIKGELTDKEKEIVGNVLDLSDKMIRADYFKDKIPNDNSKNN

Sequences:

>Translated_629_residues
MQEKVKLNNGLSKFKESLNKNALIRLGFYIFTLIAIVLKGALFLGFSLNQNLYTLNFSLGYRQASYFINYYIAFAAIFVS
ICFLFKNKGKFFSLIIVDLFITLITVMDIWYFRGFQTVPSVMLLKQTANLDNLGDSIFSMASPYDLLFFVDFIILIIAFI
IFRKSFKNCKSNWKGTLIVLLVSICYIGYVPFNVNVLKRENVKNSYLFSNYDPTNTVEYFSPIGYHIFDIYNVYKNSKPY
KMTADDEAKIKEYYDFKNENLPDNEFKGMFKGKNLIVIQVESLEDFVINKKVDGQEITPNINKLLNNSIYLPNIFEQVNE
GTSSDSDLMVNTSMLPLRQGSTFFRNPATTYNSLPNILEKDGYSTIAIHSDKGSFWNYAQGLNGIGFDKFVDYYSFDRDE
NIGLGLSDGSYFRQIEPMIKELKQPFYAFTVTLTSHGPFDLPKEYRELKLSPELDDNVLGGYFQSIHYTDAKIGMFIESL
KKDGLLDNTVIAIEGDHTGPHKYYNSKIESLSNPESWWLDNGNHTVPLIIYNPSIKTPVKDDVYGGQIDIMPTLLYLLGI
DNNVYQNTALGRNLLNTKRSYAVLTDKTIKGELTDKEKEIVGNVLDLSDKMIRADYFKDKIPNDNSKNN
>Mature_629_residues
MQEKVKLNNGLSKFKESLNKNALIRLGFYIFTLIAIVLKGALFLGFSLNQNLYTLNFSLGYRQASYFINYYIAFAAIFVS
ICFLFKNKGKFFSLIIVDLFITLITVMDIWYFRGFQTVPSVMLLKQTANLDNLGDSIFSMASPYDLLFFVDFIILIIAFI
IFRKSFKNCKSNWKGTLIVLLVSICYIGYVPFNVNVLKRENVKNSYLFSNYDPTNTVEYFSPIGYHIFDIYNVYKNSKPY
KMTADDEAKIKEYYDFKNENLPDNEFKGMFKGKNLIVIQVESLEDFVINKKVDGQEITPNINKLLNNSIYLPNIFEQVNE
GTSSDSDLMVNTSMLPLRQGSTFFRNPATTYNSLPNILEKDGYSTIAIHSDKGSFWNYAQGLNGIGFDKFVDYYSFDRDE
NIGLGLSDGSYFRQIEPMIKELKQPFYAFTVTLTSHGPFDLPKEYRELKLSPELDDNVLGGYFQSIHYTDAKIGMFIESL
KKDGLLDNTVIAIEGDHTGPHKYYNSKIESLSNPESWWLDNGNHTVPLIIYNPSIKTPVKDDVYGGQIDIMPTLLYLLGI
DNNVYQNTALGRNLLNTKRSYAVLTDKTIKGELTDKEKEIVGNVLDLSDKMIRADYFKDKIPNDNSKNN

Specific function: Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate, a reaction that presumably uses phosphatidylglycerol (PG) as substrate [H]

COG id: COG1368

COG function: function code M; Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily

Gene ontology:

Cell location: Processed glycerol phosphate lipoteichoic acid synthase 1:Secreted. Note=The secretion into the extracellular medium is dependent on secA and ffh [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LTA synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR012160
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: NA

Molecular weight: Translated: 72076; Mature: 72076

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEKVKLNNGLSKFKESLNKNALIRLGFYIFTLIAIVLKGALFLGFSLNQNLYTLNFSLG
CCCCCHHHCCHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEEECC
YRQASYFINYYIAFAAIFVSICFLFKNKGKFFSLIIVDLFITLITVMDIWYFRGFQTVPS
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
VMLLKQTANLDNLGDSIFSMASPYDLLFFVDFIILIIAFIIFRKSFKNCKSNWKGTLIVL
HHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
LVSICYIGYVPFNVNVLKRENVKNSYLFSNYDPTNTVEYFSPIGYHIFDIYNVYKNSKPY
HHHHHHHCCCCCCEEEEECCCCCCCEEECCCCCCCCHHHHCCCCHHHHHHHHHHCCCCCE
KMTADDEAKIKEYYDFKNENLPDNEFKGMFKGKNLIVIQVESLEDFVINKKVDGQEITPN
EECCCCHHHHHHHHCCCCCCCCCHHHHHHCCCCCEEEEEECCCCHHHHCCCCCCCCCCCC
INKLLNNSIYLPNIFEQVNEGTSSDSDLMVNTSMLPLRQGSTFFRNPATTYNSLPNILEK
HHHHHCCCCCCCHHHHHHCCCCCCCCCEEEECCCCEECCCCCHHCCCCCHHHHHHHHHHH
DGYSTIAIHSDKGSFWNYAQGLNGIGFDKFVDYYSFDRDENIGLGLSDGSYFRQIEPMIK
CCCEEEEEECCCCCCHHHHCCCCCCCHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHH
ELKQPFYAFTVTLTSHGPFDLPKEYRELKLSPELDDNVLGGYFQSIHYTDAKIGMFIESL
HHCCCEEEEEEEEECCCCCCCCHHHHHEECCCCCCCCHHHHHHHHHCCCCHHHHHHHHHH
KKDGLLDNTVIAIEGDHTGPHKYYNSKIESLSNPESWWLDNGNHTVPLIIYNPSIKTPVK
HHCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCEEECCCCCEEEEEEECCCCCCCCC
DDVYGGQIDIMPTLLYLLGIDNNVYQNTALGRNLLNTKRSYAVLTDKTIKGELTDKEKEI
CCCCCCEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEECCEECCCCCCHHHHH
VGNVLDLSDKMIRADYFKDKIPNDNSKNN
HHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MQEKVKLNNGLSKFKESLNKNALIRLGFYIFTLIAIVLKGALFLGFSLNQNLYTLNFSLG
CCCCCHHHCCHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEEECC
YRQASYFINYYIAFAAIFVSICFLFKNKGKFFSLIIVDLFITLITVMDIWYFRGFQTVPS
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
VMLLKQTANLDNLGDSIFSMASPYDLLFFVDFIILIIAFIIFRKSFKNCKSNWKGTLIVL
HHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
LVSICYIGYVPFNVNVLKRENVKNSYLFSNYDPTNTVEYFSPIGYHIFDIYNVYKNSKPY
HHHHHHHCCCCCCEEEEECCCCCCCEEECCCCCCCCHHHHCCCCHHHHHHHHHHCCCCCE
KMTADDEAKIKEYYDFKNENLPDNEFKGMFKGKNLIVIQVESLEDFVINKKVDGQEITPN
EECCCCHHHHHHHHCCCCCCCCCHHHHHHCCCCCEEEEEECCCCHHHHCCCCCCCCCCCC
INKLLNNSIYLPNIFEQVNEGTSSDSDLMVNTSMLPLRQGSTFFRNPATTYNSLPNILEK
HHHHHCCCCCCCHHHHHHCCCCCCCCCEEEECCCCEECCCCCHHCCCCCHHHHHHHHHHH
DGYSTIAIHSDKGSFWNYAQGLNGIGFDKFVDYYSFDRDENIGLGLSDGSYFRQIEPMIK
CCCEEEEEECCCCCCHHHHCCCCCCCHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHH
ELKQPFYAFTVTLTSHGPFDLPKEYRELKLSPELDDNVLGGYFQSIHYTDAKIGMFIESL
HHCCCEEEEEEEEECCCCCCCCHHHHHEECCCCCCCCHHHHHHHHHCCCCHHHHHHHHHH
KKDGLLDNTVIAIEGDHTGPHKYYNSKIESLSNPESWWLDNGNHTVPLIIYNPSIKTPVK
HHCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCEEECCCCCEEEEEEECCCCCCCCC
DDVYGGQIDIMPTLLYLLGIDNNVYQNTALGRNLLNTKRSYAVLTDKTIKGELTDKEKEI
CCCCCCEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEECCEECCCCCCHHHHH
VGNVLDLSDKMIRADYFKDKIPNDNSKNN
HHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377; 10658653 [H]