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The map label for this gene is tesA [C]

Identifier: 18311216

GI number: 18311216

Start: 2555760

End: 2556320

Strand: Direct

Name: tesA [C]

Synonym: CPE2234

Alternate gene names: 18311216

Gene position: 2555760-2556320 (Clockwise)

Preceding gene: 18311215

Following gene: 18311219

Centisome position: 84.31

GC content: 24.78

Gene sequence:

>561_bases
ATGAATATAATTTGTATAGGTGACTCTCTTACCTTTGGCTATGGTGTAGGACAAGAAAATTCTTGGGTTTCTCTTTTAAA
TGATGAAAAAAACAAATTCATAAACAAAGGGGTTAATGGTGACACTTCAACTGGTATTTTATCTAGAATATATGAAATCT
TAAAATCAAGTGATTCTAAGATTTGTTTAATTATGTGTGGCTCAAATGATATTATAATGAATAAATCTATTAGTTCAATT
ATTGATAACATAAGCTTAATGACTGATGATTGTAATTCACTTAACATAAAACCAATAATTTTATCTCCCCCTAAAATATA
TGGTTATTTAGCTATTAAAAGGTGGGATTCTTCTATTGATTATGAAAAATGTAATTCTAAACTAGAGAATTATACTAGAG
GATTAAATTTATTCTGTGAAAAAAACAATTTGTTGTTTATAGACTTAAACTCTAATCTTCCTTTTGATTCTTTAAATTAT
ACTGATGGATTGCACTTAAGCATAAAAGGAAATATATTAGTATCTAATTTAGTAAAAATGAGTTTAAAAAATTATCTTTA
A

Upstream 100 bases:

>100_bases
CTATTTGTAATAAAGCTATTATTGGAAATGATTTTGTTACAGCTAATAAAGGGACAACCATTATTTGCAAAAAATGTTTA
CTAAGAATGTAGGTGATTAT

Downstream 100 bases:

>100_bases
TTCTATACCTTTGAAATTTTGAAAATTTCACTGAAACAAATATTTCTTTGTAATTATAACCTTCTTTAAAGCATAAAATA
AGACTAAAATTCAAAATTAA

Product: acyl-CoA thioesterase I

Products: @ACYL02.txt*Glycerophosphocholine!; A Fatty Acid Anion. [C]

Alternate protein names: Arylesterase; Acyl-CoA Thioesterase; Lysophospholipase; GDSL Family Lipase; Lipase/Acylhydrolase GDSL Family; TesA-Like Protease; Lipolytic G-D-S-L; GDSL-Like Lipase/Acylhydrolase

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MNIICIGDSLTFGYGVGQENSWVSLLNDEKNKFINKGVNGDTSTGILSRIYEILKSSDSKICLIMCGSNDIIMNKSISSI
IDNISLMTDDCNSLNIKPIILSPPKIYGYLAIKRWDSSIDYEKCNSKLENYTRGLNLFCEKNNLLFIDLNSNLPFDSLNY
TDGLHLSIKGNILVSNLVKMSLKNYL

Sequences:

>Translated_186_residues
MNIICIGDSLTFGYGVGQENSWVSLLNDEKNKFINKGVNGDTSTGILSRIYEILKSSDSKICLIMCGSNDIIMNKSISSI
IDNISLMTDDCNSLNIKPIILSPPKIYGYLAIKRWDSSIDYEKCNSKLENYTRGLNLFCEKNNLLFIDLNSNLPFDSLNY
TDGLHLSIKGNILVSNLVKMSLKNYL
>Mature_186_residues
MNIICIGDSLTFGYGVGQENSWVSLLNDEKNKFINKGVNGDTSTGILSRIYEILKSSDSKICLIMCGSNDIIMNKSISSI
IDNISLMTDDCNSLNIKPIILSPPKIYGYLAIKRWDSSIDYEKCNSKLENYTRGLNLFCEKNNLLFIDLNSNLPFDSLNY
TDGLHLSIKGNILVSNLVKMSLKNYL

Specific function: Hydrolyzes Only Long Chain Acyl Thioesters (C12-C18). Specificity Similar To Chymotrypsin. [C]

COG id: COG2755

COG function: function code E; Lysophospholipase L1 and related esterases

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.1.2.- [C]

Molecular weight: Translated: 20825; Mature: 20825

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIICIGDSLTFGYGVGQENSWVSLLNDEKNKFINKGVNGDTSTGILSRIYEILKSSDSK
CEEEEEECCCEEEECCCCCCCEEEEECCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCC
ICLIMCGSNDIIMNKSISSIIDNISLMTDDCNSLNIKPIILSPPKIYGYLAIKRWDSSID
EEEEEECCCCEEECCCHHHHHHCCEEEECCCCCCCEEEEEECCCCEEEEEEEEECCCCCC
YEKCNSKLENYTRGLNLFCEKNNLLFIDLNSNLPFDSLNYTDGLHLSIKGNILVSNLVKM
HHHHHHHHHHHHCCEEEEEECCCEEEEEECCCCCCCCCCCCCCEEEEEECCCHHHHHHHH
SLKNYL
HHHHCC
>Mature Secondary Structure
MNIICIGDSLTFGYGVGQENSWVSLLNDEKNKFINKGVNGDTSTGILSRIYEILKSSDSK
CEEEEEECCCEEEECCCCCCCEEEEECCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCC
ICLIMCGSNDIIMNKSISSIIDNISLMTDDCNSLNIKPIILSPPKIYGYLAIKRWDSSID
EEEEEECCCCEEECCCHHHHHHCCEEEECCCCCCCEEEEEECCCCEEEEEEEEECCCCCC
YEKCNSKLENYTRGLNLFCEKNNLLFIDLNSNLPFDSLNYTDGLHLSIKGNILVSNLVKM
HHHHHHHHHHHHCCEEEEEECCCEEEEEECCCCCCCCCCCCCCEEEEEECCCHHHHHHHH
SLKNYL
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Lysophosphatidiylcholine; H2O [C]

Specific reaction: 2-Lysophosphatidiylcholine + H2O = @ACYL02.txt*Glycerophosphocholine! + A Fatty Acid Anion. [C]

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA