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The map label for this gene is resE [H]

Identifier: 18310969

GI number: 18310969

Start: 2275823

End: 2277709

Strand: Reverse

Name: resE [H]

Synonym: CPE1987

Alternate gene names: 18310969

Gene position: 2277709-2275823 (Counterclockwise)

Preceding gene: 18310970

Following gene: 18310968

Centisome position: 75.14

GC content: 22.1

Gene sequence:

>1887_bases
TTGGAGTACATAGAAAATGACTATATGTATTTGAAACTTAGTAAAATTAGAAATTTAGTTAATATTATTATATTTATAGC
AATTATTTTATATACTGTATATTTTTTTAATCCACGTACAGCTCTTTATTTATCTACAATTATTGAAACTATATTAGTGT
TTACTATAACATTTATTGCTACAACTGTATTTAAGTTTTCTAATAAAAAGATTTTTAAATTAATAGGTATTTATTTATTA
TTAGTTGCCATATTCAAGTTTGATATACTTGTTTATTTAATAGCCTTTTGGAGCGAAAAAGAAATAATTCAATGTTTAGA
TTTAAAACCAGTAGCTATTTGTACTGTTTTAGAAAGTGTATATTGCTTTATGATAATAGCATATGTAAAGTCAGTAGATT
TAAATATAAAATTAATAGTTTGTTTTTTTAGCATAGTGTCATTAATCAGTATATTTTTTTATGATATAAGTGTTTTTTGG
GGGATATCAACAGTCCTTCTTTTAATAATTTTATGTCTTTTAAGAAATTTTAAACTTTTTAAAAATAATTTATTAAATTA
TTTAAAGTTATTTGTGCTAATAAATTTATCTATAGTAGTATTAGATATTTTATCATATAGTTTAGGTTTAGAGTCACTTA
TACTATTAGGTGATATATTAAAAATATCAATCTATTTAATTATATATGTTTGGATTTCAGAAATGCTTATTATAAAACCA
TATAAAACTCTACATGAAGATATAATTGATAAAAATAAAAAACTTAAAATATTAAATAAGAAAATGGAAGAGAGTAATAA
TGAGTTTAAAGAATTTAAGAAAAAATTAAGAGATAATGAAATTTATTTTAGGAACTTTTTAAATAATGCACCTATGTCTA
TAGCGATTTTAAATAATGATAATCATAGGATTTTTGCTGTGAATAAAAGATTTTCACATGAATTAAATTTAAAAAGTAAT
AGAGAGGTAATAAATAAGAACTTATTTAAAATAATAAATATTGAAAATAAAGAGGAATTCTTAAGAACAAAAAAGGGAGA
AGCTTCATTTGTTACTTCTGGAATAGAAGTTTTTTGGGAGTTAGATATTTTACTACAATCAAAGGGTTACTTAATAATAT
CAATGAAAAATATAACTGAACTTAAGTTTTCAGAAAAGATAAAAGATAATTTAAGAAAAAGAACCTTATCAGAACAAATA
AAAAATGATTTTTTATCAAGTATTTCTCATGACTTAAAAACTCCTATAAATGTTATATATTCATCAGTTCAAGTGCAGGA
GAAATTTTATAGTAATGAAAATATTAAAAAAGTTGATTATTATAACCAAGTTAATAAGGAAAATTGTATGACCTTACTAA
GGTTAGCTAACAATCTAATTGACTCATCCAAAATTGATTACGATTATTTAAAACCAAACTTTAAAATTTATAATATAGTA
ACATTGATTGAAGATTCTATAGGAAATTTAGCTGAATATATAAAAGAGAAAAATTTAACTTACGTATTTGATACCAATGA
AGAAGAAGTATATGTTAGGTGCGATCAAGAATTTATTCAGAGAATTATTTTAAACTTAATTTCAAATTCAATAAAGCATA
CAAGGGAAGGTGGAATTGGAGTAGAGATTAAGGCAAAGAAAAGTAAAGTTATTATTAGTTTTACAGACACTGGTGAAGGC
ATGGATAAAGAATTTATAGAAAAGGCTTTCTTAAGATATAGCAAGGGAAATAAAAAAGGAGTAAAAAATAAAAGTACAGG
AATTGGATTATATATTGTTAAGAATTTAGTTGAATTGCAAAATGGAACTATAAATATAAATTCAATTAAGGATACAGGAA
CAAATATAAGGTTGGAATTTAGTAGGGAGAAAAGTTGTGGAATATAA

Upstream 100 bases:

>100_bases
TAAATTACAATTAAATACAATAATTTACAAAAATTAAATAATTTCCTCTCTTTTTTATGATAATGTATATTTATATGGTT
ATATTTAAGGGGGAAGTATA

Downstream 100 bases:

>100_bases
AGTAGAATATGAAAATCCTAAATTACAATATTATATATTAAGAGTAATATATATATTAATAATACTATCAGCAGTATTGT
TTATAAGAAAAGAAAAATAT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 628; Mature: 628

Protein sequence:

>628_residues
MEYIENDYMYLKLSKIRNLVNIIIFIAIILYTVYFFNPRTALYLSTIIETILVFTITFIATTVFKFSNKKIFKLIGIYLL
LVAIFKFDILVYLIAFWSEKEIIQCLDLKPVAICTVLESVYCFMIIAYVKSVDLNIKLIVCFFSIVSLISIFFYDISVFW
GISTVLLLIILCLLRNFKLFKNNLLNYLKLFVLINLSIVVLDILSYSLGLESLILLGDILKISIYLIIYVWISEMLIIKP
YKTLHEDIIDKNKKLKILNKKMEESNNEFKEFKKKLRDNEIYFRNFLNNAPMSIAILNNDNHRIFAVNKRFSHELNLKSN
REVINKNLFKIINIENKEEFLRTKKGEASFVTSGIEVFWELDILLQSKGYLIISMKNITELKFSEKIKDNLRKRTLSEQI
KNDFLSSISHDLKTPINVIYSSVQVQEKFYSNENIKKVDYYNQVNKENCMTLLRLANNLIDSSKIDYDYLKPNFKIYNIV
TLIEDSIGNLAEYIKEKNLTYVFDTNEEEVYVRCDQEFIQRIILNLISNSIKHTREGGIGVEIKAKKSKVIISFTDTGEG
MDKEFIEKAFLRYSKGNKKGVKNKSTGIGLYIVKNLVELQNGTININSIKDTGTNIRLEFSREKSCGI

Sequences:

>Translated_628_residues
MEYIENDYMYLKLSKIRNLVNIIIFIAIILYTVYFFNPRTALYLSTIIETILVFTITFIATTVFKFSNKKIFKLIGIYLL
LVAIFKFDILVYLIAFWSEKEIIQCLDLKPVAICTVLESVYCFMIIAYVKSVDLNIKLIVCFFSIVSLISIFFYDISVFW
GISTVLLLIILCLLRNFKLFKNNLLNYLKLFVLINLSIVVLDILSYSLGLESLILLGDILKISIYLIIYVWISEMLIIKP
YKTLHEDIIDKNKKLKILNKKMEESNNEFKEFKKKLRDNEIYFRNFLNNAPMSIAILNNDNHRIFAVNKRFSHELNLKSN
REVINKNLFKIINIENKEEFLRTKKGEASFVTSGIEVFWELDILLQSKGYLIISMKNITELKFSEKIKDNLRKRTLSEQI
KNDFLSSISHDLKTPINVIYSSVQVQEKFYSNENIKKVDYYNQVNKENCMTLLRLANNLIDSSKIDYDYLKPNFKIYNIV
TLIEDSIGNLAEYIKEKNLTYVFDTNEEEVYVRCDQEFIQRIILNLISNSIKHTREGGIGVEIKAKKSKVIISFTDTGEG
MDKEFIEKAFLRYSKGNKKGVKNKSTGIGLYIVKNLVELQNGTININSIKDTGTNIRLEFSREKSCGI
>Mature_628_residues
MEYIENDYMYLKLSKIRNLVNIIIFIAIILYTVYFFNPRTALYLSTIIETILVFTITFIATTVFKFSNKKIFKLIGIYLL
LVAIFKFDILVYLIAFWSEKEIIQCLDLKPVAICTVLESVYCFMIIAYVKSVDLNIKLIVCFFSIVSLISIFFYDISVFW
GISTVLLLIILCLLRNFKLFKNNLLNYLKLFVLINLSIVVLDILSYSLGLESLILLGDILKISIYLIIYVWISEMLIIKP
YKTLHEDIIDKNKKLKILNKKMEESNNEFKEFKKKLRDNEIYFRNFLNNAPMSIAILNNDNHRIFAVNKRFSHELNLKSN
REVINKNLFKIINIENKEEFLRTKKGEASFVTSGIEVFWELDILLQSKGYLIISMKNITELKFSEKIKDNLRKRTLSEQI
KNDFLSSISHDLKTPINVIYSSVQVQEKFYSNENIKKVDYYNQVNKENCMTLLRLANNLIDSSKIDYDYLKPNFKIYNIV
TLIEDSIGNLAEYIKEKNLTYVFDTNEEEVYVRCDQEFIQRIILNLISNSIKHTREGGIGVEIKAKKSKVIISFTDTGEG
MDKEFIEKAFLRYSKGNKKGVKNKSTGIGLYIVKNLVELQNGTININSIKDTGTNIRLEFSREKSCGI

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=241, Percent_Identity=21.5767634854772, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI145693157, Length=241, Percent_Identity=25.7261410788382, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1788393, Length=234, Percent_Identity=24.3589743589744, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788713, Length=235, Percent_Identity=23.8297872340426, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI48994928, Length=410, Percent_Identity=22.1951219512195, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1789149, Length=227, Percent_Identity=23.3480176211454, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1786600, Length=405, Percent_Identity=19.7530864197531, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790436, Length=220, Percent_Identity=23.1818181818182, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 73256; Mature: 73256

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYIENDYMYLKLSKIRNLVNIIIFIAIILYTVYFFNPRTALYLSTIIETILVFTITFIA
CCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
TTVFKFSNKKIFKLIGIYLLLVAIFKFDILVYLIAFWSEKEIIQCLDLKPVAICTVLESV
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHH
YCFMIIAYVKSVDLNIKLIVCFFSIVSLISIFFYDISVFWGISTVLLLIILCLLRNFKLF
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KNNLLNYLKLFVLINLSIVVLDILSYSLGLESLILLGDILKISIYLIIYVWISEMLIIKP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
YKTLHEDIIDKNKKLKILNKKMEESNNEFKEFKKKLRDNEIYFRNFLNNAPMSIAILNND
HHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEEECC
NHRIFAVNKRFSHELNLKSNREVINKNLFKIINIENKEEFLRTKKGEASFVTSGIEVFWE
CCEEEEEECCCCCCCCCCCCHHHHHCCCEEEEECCCHHHHHHCCCCCHHHHHHHHHHHEE
LDILLQSKGYLIISMKNITELKFSEKIKDNLRKRTLSEQIKNDFLSSISHDLKTPINVIY
EEHEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
SSVQVQEKFYSNENIKKVDYYNQVNKENCMTLLRLANNLIDSSKIDYDYLKPNFKIYNIV
HHHHHHHHHHCCCCCEEEHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHCCCCCEEEHHH
TLIEDSIGNLAEYIKEKNLTYVFDTNEEEVYVRCDQEFIQRIILNLISNSIKHTREGGIG
HHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCE
VEIKAKKSKVIISFTDTGEGMDKEFIEKAFLRYSKGNKKGVKNKSTGIGLYIVKNLVELQ
EEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHC
NGTININSIKDTGTNIRLEFSREKSCGI
CCEEEEEEECCCCCEEEEEECCCCCCCC
>Mature Secondary Structure
MEYIENDYMYLKLSKIRNLVNIIIFIAIILYTVYFFNPRTALYLSTIIETILVFTITFIA
CCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
TTVFKFSNKKIFKLIGIYLLLVAIFKFDILVYLIAFWSEKEIIQCLDLKPVAICTVLESV
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHH
YCFMIIAYVKSVDLNIKLIVCFFSIVSLISIFFYDISVFWGISTVLLLIILCLLRNFKLF
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KNNLLNYLKLFVLINLSIVVLDILSYSLGLESLILLGDILKISIYLIIYVWISEMLIIKP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
YKTLHEDIIDKNKKLKILNKKMEESNNEFKEFKKKLRDNEIYFRNFLNNAPMSIAILNND
HHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEEECC
NHRIFAVNKRFSHELNLKSNREVINKNLFKIINIENKEEFLRTKKGEASFVTSGIEVFWE
CCEEEEEECCCCCCCCCCCCHHHHHCCCEEEEECCCHHHHHHCCCCCHHHHHHHHHHHEE
LDILLQSKGYLIISMKNITELKFSEKIKDNLRKRTLSEQIKNDFLSSISHDLKTPINVIY
EEHEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
SSVQVQEKFYSNENIKKVDYYNQVNKENCMTLLRLANNLIDSSKIDYDYLKPNFKIYNIV
HHHHHHHHHHCCCCCEEEHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHCCCCCEEEHHH
TLIEDSIGNLAEYIKEKNLTYVFDTNEEEVYVRCDQEFIQRIILNLISNSIKHTREGGIG
HHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCE
VEIKAKKSKVIISFTDTGEGMDKEFIEKAFLRYSKGNKKGVKNKSTGIGLYIVKNLVELQ
EEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHC
NGTININSIKDTGTNIRLEFSREKSCGI
CCEEEEEEECCCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]