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The map label for this gene is yycG [H]

Identifier: 18310968

GI number: 18310968

Start: 2273797

End: 2275833

Strand: Reverse

Name: yycG [H]

Synonym: CPE1986

Alternate gene names: 18310968

Gene position: 2275833-2273797 (Counterclockwise)

Preceding gene: 18310969

Following gene: 18310967

Centisome position: 75.07

GC content: 22.24

Gene sequence:

>2037_bases
GTGGAATATAAAGTAGAATATGAAAATCCTAAATTACAATATTATATATTAAGAGTAATATATATATTAATAATACTATC
AGCAGTATTGTTTATAAGAAAAGAAAAATATATTATGTTTTATAAATTTTTAGACTTGTCTTCAGTAATAATGTTAGGAA
CCTCATTATTAATAGGAATAAGCAGTAATGTAGATAAGGAAAAAAACTTAGTTTCTTATACTAATATGGGGATATTTTGG
ATTATTATTCCTGAGGTTTTTTCTTCATTTGTTTCCTTGGAGTTATATGTAGTAGATAAGATGATAGCTTATAAAATAAT
AGGCATATTATTTCAGTATTTTATTACCCTTGTAATAGTTTTAGGGAAGAAAAAGGACTTAGCTTTTAAGAAAATAAATA
AAATTTTTCTATTATTAAATATTATCTTTAACATTATTTATCTCATAGTAATAAATAATACAAAATTAATGAGAGCTTTT
ATTAAAGGTGTATATATAAATAATTTTATGTTTATATTGATTGTTATTTTATTTTTAATATTATTAATAGTAATTGTTGC
TGATAAAGAAAATACATCTGATAAATTCTTTTATTATTTAATTGCTTATATATTATTATTCTCAGTAGAAAATATTATTT
TATTAAATAATCTTCATAATTTAAGAAATACTTATTTATTAGGAGTTTCCTTTAGCCAAATACTAGACTTCTCAGCATAT
TACATTTTAGTAGAAGGTATAATAAGATTTTCTTTAAATAAGAATTTTAATAATATAAATAAGATAATGCTCTTAAAAAG
AGGTGAATTTAAGAGAAATAAAAGGTATTTAAGAAAAAAAATAGAGGAGCTAAAAGAATTAGAGAATCTTTTAGATAGAG
AAGAATTGTTGTTTAATAATATTACTTCAGCCATTGGAGACTATATATTTATTTCTAAGGATGAAAAATTATTTTATTTA
AACGACGAAGCCTTGGAATTTTTAGAAGTTGAAAACAAAGAATCCATATTGTTTGAAAGTATGGAAGTTTTATATGAAAA
AATACTAGAAAAGCAAGTTTATTTAAAAGAGAAAGGAAGTATGGATTCTTATAAAGAAATAATTTTTAAAAATATTAAGG
GAGGCTACTCTAATGGAGAATTTTACACAATACCTTTTGGAGATAATTATAAAATTATAATTATAAATGATATTACTAAA
AAAAATAATGCTTTAAGGTTAAATAAGTATTTAAAAGATAAATTAGAAGAAGAAAATATAAAGGGAGAATTTTTTACAAA
TATATGTCATGAGTTAAGGACTCCTATAAATGTAATAAGTTCAGCTCTTCAATTAAACAATTTAAATATAGAAAATAGAA
ATCTTAAGTCTATAGAAAGAAATAACCTAGTAATTAAACAAAATTGTTTAAGACTTATAAGAACAATAAATAATTTCATT
GATGCTAATAAAATATCAGAGGGGCAGATAGAAGAAAACGTTATGGTTCTTAATGTAGTTGAAGTTGTTGAAAATATATT
AGATGCCTCTTCGGAATATATAAGTAAGAAAAAAATAAATTTTATTTTTGATCCAGACTTTGAAGAGATATTTATAGCTA
TTGATAGTGAGTTTTTAGAAAGAATAATATTAAATCTATTATCAAATTCAGTTAAGTATGGAAGAGAAAATGGAAATATA
TATGTAAAAATATATTTTGAAGGAAAAGATCTTGTAATAATGATAGAAAATGATGGAGTTGCTATAAGCTACGATGAACA
AAAATATATTTTTGATAAATTTACTAAGAGCAATAAGGCTTTAAATAGAACACAAGAAGGAAGTGGGTTAGGGCTTTATA
TAAGTAAATCCCTTATGAAAATGCAAGGGGGAGACTTAAAGGTTGACATATATGAGGGACATGGAAATAGATTTAAATTA
TATTTTTATGATGTAGATTTATTTAAGGAAACTGATAGGACAGAACATATTTTTAATAACAATTACTACAACTTAAAGGA
AAGAGCTGAAATTGAATTTTCTGATATATACATATAA

Upstream 100 bases:

>100_bases
GTTAAGAATTTAGTTGAATTGCAAAATGGAACTATAAATATAAATTCAATTAAGGATACAGGAACAAATATAAGGTTGGA
ATTTAGTAGGGAGAAAAGTT

Downstream 100 bases:

>100_bases
TATATATCAAAAGGAATACATATAATTACCTGAGAGGTGATTTATGTGAATATATTCAAGGTTAATGGAAAATTTAATTT
AGGTGATTTAATAATAAGTT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 678; Mature: 678

Protein sequence:

>678_residues
MEYKVEYENPKLQYYILRVIYILIILSAVLFIRKEKYIMFYKFLDLSSVIMLGTSLLIGISSNVDKEKNLVSYTNMGIFW
IIIPEVFSSFVSLELYVVDKMIAYKIIGILFQYFITLVIVLGKKKDLAFKKINKIFLLLNIIFNIIYLIVINNTKLMRAF
IKGVYINNFMFILIVILFLILLIVIVADKENTSDKFFYYLIAYILLFSVENIILLNNLHNLRNTYLLGVSFSQILDFSAY
YILVEGIIRFSLNKNFNNINKIMLLKRGEFKRNKRYLRKKIEELKELENLLDREELLFNNITSAIGDYIFISKDEKLFYL
NDEALEFLEVENKESILFESMEVLYEKILEKQVYLKEKGSMDSYKEIIFKNIKGGYSNGEFYTIPFGDNYKIIIINDITK
KNNALRLNKYLKDKLEEENIKGEFFTNICHELRTPINVISSALQLNNLNIENRNLKSIERNNLVIKQNCLRLIRTINNFI
DANKISEGQIEENVMVLNVVEVVENILDASSEYISKKKINFIFDPDFEEIFIAIDSEFLERIILNLLSNSVKYGRENGNI
YVKIYFEGKDLVIMIENDGVAISYDEQKYIFDKFTKSNKALNRTQEGSGLGLYISKSLMKMQGGDLKVDIYEGHGNRFKL
YFYDVDLFKETDRTEHIFNNNYYNLKERAEIEFSDIYI

Sequences:

>Translated_678_residues
MEYKVEYENPKLQYYILRVIYILIILSAVLFIRKEKYIMFYKFLDLSSVIMLGTSLLIGISSNVDKEKNLVSYTNMGIFW
IIIPEVFSSFVSLELYVVDKMIAYKIIGILFQYFITLVIVLGKKKDLAFKKINKIFLLLNIIFNIIYLIVINNTKLMRAF
IKGVYINNFMFILIVILFLILLIVIVADKENTSDKFFYYLIAYILLFSVENIILLNNLHNLRNTYLLGVSFSQILDFSAY
YILVEGIIRFSLNKNFNNINKIMLLKRGEFKRNKRYLRKKIEELKELENLLDREELLFNNITSAIGDYIFISKDEKLFYL
NDEALEFLEVENKESILFESMEVLYEKILEKQVYLKEKGSMDSYKEIIFKNIKGGYSNGEFYTIPFGDNYKIIIINDITK
KNNALRLNKYLKDKLEEENIKGEFFTNICHELRTPINVISSALQLNNLNIENRNLKSIERNNLVIKQNCLRLIRTINNFI
DANKISEGQIEENVMVLNVVEVVENILDASSEYISKKKINFIFDPDFEEIFIAIDSEFLERIILNLLSNSVKYGRENGNI
YVKIYFEGKDLVIMIENDGVAISYDEQKYIFDKFTKSNKALNRTQEGSGLGLYISKSLMKMQGGDLKVDIYEGHGNRFKL
YFYDVDLFKETDRTEHIFNNNYYNLKERAEIEFSDIYI
>Mature_678_residues
MEYKVEYENPKLQYYILRVIYILIILSAVLFIRKEKYIMFYKFLDLSSVIMLGTSLLIGISSNVDKEKNLVSYTNMGIFW
IIIPEVFSSFVSLELYVVDKMIAYKIIGILFQYFITLVIVLGKKKDLAFKKINKIFLLLNIIFNIIYLIVINNTKLMRAF
IKGVYINNFMFILIVILFLILLIVIVADKENTSDKFFYYLIAYILLFSVENIILLNNLHNLRNTYLLGVSFSQILDFSAY
YILVEGIIRFSLNKNFNNINKIMLLKRGEFKRNKRYLRKKIEELKELENLLDREELLFNNITSAIGDYIFISKDEKLFYL
NDEALEFLEVENKESILFESMEVLYEKILEKQVYLKEKGSMDSYKEIIFKNIKGGYSNGEFYTIPFGDNYKIIIINDITK
KNNALRLNKYLKDKLEEENIKGEFFTNICHELRTPINVISSALQLNNLNIENRNLKSIERNNLVIKQNCLRLIRTINNFI
DANKISEGQIEENVMVLNVVEVVENILDASSEYISKKKINFIFDPDFEEIFIAIDSEFLERIILNLLSNSVKYGRENGNI
YVKIYFEGKDLVIMIENDGVAISYDEQKYIFDKFTKSNKALNRTQEGSGLGLYISKSLMKMQGGDLKVDIYEGHGNRFKL
YFYDVDLFKETDRTEHIFNNNYYNLKERAEIEFSDIYI

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=209, Percent_Identity=28.2296650717703, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788713, Length=276, Percent_Identity=29.7101449275362, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI48994928, Length=418, Percent_Identity=23.6842105263158, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI145693157, Length=260, Percent_Identity=25.7692307692308, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1789149, Length=246, Percent_Identity=27.2357723577236, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786600, Length=465, Percent_Identity=22.5806451612903, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI87082128, Length=226, Percent_Identity=26.1061946902655, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788549, Length=256, Percent_Identity=26.171875, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1786783, Length=219, Percent_Identity=25.1141552511416, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787894, Length=226, Percent_Identity=23.0088495575221, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1788393, Length=208, Percent_Identity=22.1153846153846, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 79834; Mature: 79834

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYKVEYENPKLQYYILRVIYILIILSAVLFIRKEKYIMFYKFLDLSSVIMLGTSLLIGI
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHEEEE
SSNVDKEKNLVSYTNMGIFWIIIPEVFSSFVSLELYVVDKMIAYKIIGILFQYFITLVIV
CCCCCCCCCEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGKKKDLAFKKINKIFLLLNIIFNIIYLIVINNTKLMRAFIKGVYINNFMFILIVILFLI
HCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLIVIVADKENTSDKFFYYLIAYILLFSVENIILLNNLHNLRNTYLLGVSFSQILDFSAY
HHHHEECCCCCCCCHHHHHHHHHHHHHHHCCEEEECCHHHHCCEEEEECCHHHHHHHHHH
YILVEGIIRFSLNKNFNNINKIMLLKRGEFKRNKRYLRKKIEELKELENLLDREELLFNN
HHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITSAIGDYIFISKDEKLFYLNDEALEFLEVENKESILFESMEVLYEKILEKQVYLKEKGS
HHHHHCCEEEEECCCEEEEECHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
MDSYKEIIFKNIKGGYSNGEFYTIPFGDNYKIIIINDITKKNNALRLNKYLKDKLEEENI
CHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEEEECCCCCCCCEEHHHHHHHHHHHCCC
KGEFFTNICHELRTPINVISSALQLNNLNIENRNLKSIERNNLVIKQNCLRLIRTINNFI
CHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHCCEEEHHHHHHHHHHHHHHH
DANKISEGQIEENVMVLNVVEVVENILDASSEYISKKKINFIFDPDFEEIFIAIDSEFLE
CCCCCCCCCCCCCEEEEEHHHHHHHHHCCCHHHHHHCCEEEEECCCHHHEEEEECHHHHH
RIILNLLSNSVKYGRENGNIYVKIYFEGKDLVIMIENDGVAISYDEQKYIFDKFTKSNKA
HHHHHHHHHHHHCCCCCCEEEEEEEECCCEEEEEEECCCEEEEECCCHHHHHHHHCCCHH
LNRTQEGSGLGLYISKSLMKMQGGDLKVDIYEGHGNRFKLYFYDVDLFKETDRTEHIFNN
HCCCCCCCCEEEEEHHHHHHHCCCCEEEEEEECCCCEEEEEEEEEEHHHCCCCHHHHHCC
NYYNLKERAEIEFSDIYI
CCCCCCCCCCEEEEEECC
>Mature Secondary Structure
MEYKVEYENPKLQYYILRVIYILIILSAVLFIRKEKYIMFYKFLDLSSVIMLGTSLLIGI
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHEEEE
SSNVDKEKNLVSYTNMGIFWIIIPEVFSSFVSLELYVVDKMIAYKIIGILFQYFITLVIV
CCCCCCCCCEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGKKKDLAFKKINKIFLLLNIIFNIIYLIVINNTKLMRAFIKGVYINNFMFILIVILFLI
HCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLIVIVADKENTSDKFFYYLIAYILLFSVENIILLNNLHNLRNTYLLGVSFSQILDFSAY
HHHHEECCCCCCCCHHHHHHHHHHHHHHHCCEEEECCHHHHCCEEEEECCHHHHHHHHHH
YILVEGIIRFSLNKNFNNINKIMLLKRGEFKRNKRYLRKKIEELKELENLLDREELLFNN
HHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITSAIGDYIFISKDEKLFYLNDEALEFLEVENKESILFESMEVLYEKILEKQVYLKEKGS
HHHHHCCEEEEECCCEEEEECHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
MDSYKEIIFKNIKGGYSNGEFYTIPFGDNYKIIIINDITKKNNALRLNKYLKDKLEEENI
CHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEEEECCCCCCCCEEHHHHHHHHHHHCCC
KGEFFTNICHELRTPINVISSALQLNNLNIENRNLKSIERNNLVIKQNCLRLIRTINNFI
CHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHCCEEEHHHHHHHHHHHHHHH
DANKISEGQIEENVMVLNVVEVVENILDASSEYISKKKINFIFDPDFEEIFIAIDSEFLE
CCCCCCCCCCCCCEEEEEHHHHHHHHHCCCHHHHHHCCEEEEECCCHHHEEEEECHHHHH
RIILNLLSNSVKYGRENGNIYVKIYFEGKDLVIMIENDGVAISYDEQKYIFDKFTKSNKA
HHHHHHHHHHHHCCCCCCEEEEEEEECCCEEEEEEECCCEEEEECCCHHHHHHHHCCCHH
LNRTQEGSGLGLYISKSLMKMQGGDLKVDIYEGHGNRFKLYFYDVDLFKETDRTEHIFNN
HCCCCCCCCEEEEEHHHHHHHCCCCEEEEEEECCCCEEEEEEEEEEHHHCCCCHHHHHCC
NYYNLKERAEIEFSDIYI
CCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]