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The map label for this gene is pbpA [H]

Identifier: 18310945

GI number: 18310945

Start: 2252578

End: 2253012

Strand: Direct

Name: pbpA [H]

Synonym: CPE1963

Alternate gene names: 18310945

Gene position: 2252578-2253012 (Clockwise)

Preceding gene: 18310944

Following gene: 18310946

Centisome position: 74.31

GC content: 31.72

Gene sequence:

>435_bases
ATGGATTCAGGTCTTAAACCTACTTCCCTTTGTACTCAAGATCCTAGAGGCAGTAGAGTTTATTATGATTGGTTTATTAA
TGGTTCTGCTCCTACTCAATATTGTAATTATCATACAAATTCACATGTAAATGCTCCTGATACAAATGATAATAATAATT
CTGGAGCAAATGAAGGAAATAAACAACAAGAAACTAAACCTGAAGAAGTTAAACCTAACGAAAATAATAATAATAAACCA
AATGAACAAAATCCAAATACTAAGCCTGATAATACACCAGCTAATGGTAATAATAACACTAATAATAACGGAGGTGGAAA
TGTGACTCCTCCTCAAAATCAAACAGAAAACAATACAAATAATGGAGTTATTACTCCACCTCAAGCTGGAAATAACCAAA
ATCAAAACGGTCAAAACAACAACATTACGCAATAG

Upstream 100 bases:

>100_bases
TTACCTCTCCTATTTTCGGAAAAATAATGGGCTTAGCTCATAAAGACTTACAGTACAAAGAGGTTGACAACCTAGTGGAA
TAAGCAAGGTTGCAGTATGT

Downstream 100 bases:

>100_bases
AAGGAAGTCCTTCTTGCATTTTGACCTTATTCAAAACAAAGCCACTATGAATTTTTTATTTCATAGTGGCTTTATTATTG
ATAATTAGCCCTCTATAGCT

Product: hypothetical protein

Products: NA

Alternate protein names: PBP1a; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MDSGLKPTSLCTQDPRGSRVYYDWFINGSAPTQYCNYHTNSHVNAPDTNDNNNSGANEGNKQQETKPEEVKPNENNNNKP
NEQNPNTKPDNTPANGNNNTNNNGGGNVTPPQNQTENNTNNGVITPPQAGNNQNQNGQNNNITQ

Sequences:

>Translated_144_residues
MDSGLKPTSLCTQDPRGSRVYYDWFINGSAPTQYCNYHTNSHVNAPDTNDNNNSGANEGNKQQETKPEEVKPNENNNNKP
NEQNPNTKPDNTPANGNNNTNNNGGGNVTPPQNQTENNTNNGVITPPQAGNNQNQNGQNNNITQ
>Mature_144_residues
MDSGLKPTSLCTQDPRGSRVYYDWFINGSAPTQYCNYHTNSHVNAPDTNDNNNSGANEGNKQQETKPEEVKPNENNNNKP
NEQNPNTKPDNTPANGNNNTNNNGGGNVTPPQNQTENNTNNGVITPPQAGNNQNQNGQNNNITQ

Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transpeptidase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001264
- InterPro:   IPR011816
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 15678; Mature: 15678

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSGLKPTSLCTQDPRGSRVYYDWFINGSAPTQYCNYHTNSHVNAPDTNDNNNSGANEGN
CCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCC
KQQETKPEEVKPNENNNNKPNEQNPNTKPDNTPANGNNNTNNNGGGNVTPPQNQTENNTN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NGVITPPQAGNNQNQNGQNNNITQ
CCEECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDSGLKPTSLCTQDPRGSRVYYDWFINGSAPTQYCNYHTNSHVNAPDTNDNNNSGANEGN
CCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCC
KQQETKPEEVKPNENNNNKPNEQNPNTKPDNTPANGNNNTNNNGGGNVTPPQNQTENNTN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NGVITPPQAGNNQNQNGQNNNITQ
CCEECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA