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The map label for this gene is glnT [H]

Identifier: 18310946

GI number: 18310946

Start: 2253306

End: 2254706

Strand: Direct

Name: glnT [H]

Synonym: CPE1964

Alternate gene names: 18310946

Gene position: 2253306-2254706 (Clockwise)

Preceding gene: 18310945

Following gene: 18310949

Centisome position: 74.33

GC content: 32.19

Gene sequence:

>1401_bases
ATGGAAATACTTAATAACTTAGTAGTTAGTTTTAATGATTTTCTTTGGGGCTACATATTAATTATTTTATTAATAGGTGC
AGGCCTTCTATTTTCTTTTAAAACTAAATTTGTTCAATTTAGATATATAAAAGAAATGTTCCGTTTATTAGGAGACGGTA
TAGGAAAGTCAAATAAAGAAAAAGGTGGAGTTTCTTCATTTCAGGCATTTTGTATAAGTACAGCTTCAAGAGTTGGTACT
GGTAATATAGCGGGTGTTGCCATAGCCGTAGCTGTTGGTGGACCTGGGGCTGTTTTTTGGATGTGGCTTATAGCCTTAAT
AGGTTCTGCGTCTAGTTTCGTAGAAAGTACATTAGCTCAAATATATAAAACTAAGGATAAAGATTCTTTTAGAGGTGGTC
CTGCCTATTACATGGAAAAAGGACTTGGAAAGAGATGGTTAGGAATTATATTCTCAATTCTTATTACAATCTGTTTTGGA
TTCGTATTTAATGCAGTTCAAGCTAACACAGTAAGTGTTGCATTCAATAGTGCTTTCGGACTTTCAAGAGGAGCAATTGG
TATAATATTAGCAATAGTAACTGCTTTAGTTATCTTCGGTGGTATTCACAGAGTTGCTAAGGTTTCAGAAATAATAGTTC
CAATTTTAGCGGTTCTTTATATTCTTATTGCTATTATAGTTTTAATTTTAAATATTACTGAAATTCCATCAGTTTTCAAA
CTTATATTTGAATCAGCCTTTGGAATAAAACAATTAACTGCCGGTGGACTTGGTGCCGCTGTTATGCAGGGTATTAAAAG
AGGTTTATTCTCAAATGAAGCTGGTATGGGTAGTGCGCCAAATGCAGCTGCTACAGCAGATGTTACTCACCCAGTAAAAC
AAGGTTTAATTCAAACTTTAGGAGTATTTACTGATACATTATTAATTTGTTCTTGTACAGCATTTATAATACTTCTTTCA
GGTCAATACGCTGATAGTTCACTAACAGGTATAGAATTAACTCAAAAAGCTCTTGTATCTCAAATAGGACCTTTCGGAGC
TTATTTCATAGCAATTTGTATATTATTATTTGCTTTTAGTTCTATTGTAGGTAACTTCTATTACGGTCAAACAAACATAG
AGTTTATACACACTAATAAGGTATTATTAAATATATACAGAATACTTGTTATAGGCATGGTATTATTTGGTTCAATAGCA
AAAGTAGATTTAGTTTGGAATTTAGCGGATCTTTTCATGGGATTAATGGCTATACTAAATATAATAACTATATTATTCCT
TGGTAAATATTCTTTCCTTGCACTTAAGGACTATACAGCTCAAAAGAAAGCAGGAATTAAAGAGCCAGTATTTAAAGCAT
CTTCTATTCCTGGATTAGAAAATGTAGAAGAATGGCAATAA

Upstream 100 bases:

>100_bases
AAGTAATATTAGTTCTTGCATTTTTTTATTATTCATATTAAAATTAGATATAAAGTGTGACGCAAAAAAATAAAAAACTT
ATCAACAGGAGGAGGAATTT

Downstream 100 bases:

>100_bases
TAAAAAAAGCTTTGAGATTTTTTTCTCAAAGCTTTTTTATATTAATCTTTCAAATATAACTTTTTTCTCCACACTTAAAT
CCTTAGGATTTATTGTTATT

Product: amino acid carrier protein

Products: Na (I) [Cytoplasm]; L-alanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MEILNNLVVSFNDFLWGYILIILLIGAGLLFSFKTKFVQFRYIKEMFRLLGDGIGKSNKEKGGVSSFQAFCISTASRVGT
GNIAGVAIAVAVGGPGAVFWMWLIALIGSASSFVESTLAQIYKTKDKDSFRGGPAYYMEKGLGKRWLGIIFSILITICFG
FVFNAVQANTVSVAFNSAFGLSRGAIGIILAIVTALVIFGGIHRVAKVSEIIVPILAVLYILIAIIVLILNITEIPSVFK
LIFESAFGIKQLTAGGLGAAVMQGIKRGLFSNEAGMGSAPNAAATADVTHPVKQGLIQTLGVFTDTLLICSCTAFIILLS
GQYADSSLTGIELTQKALVSQIGPFGAYFIAICILLFAFSSIVGNFYYGQTNIEFIHTNKVLLNIYRILVIGMVLFGSIA
KVDLVWNLADLFMGLMAILNIITILFLGKYSFLALKDYTAQKKAGIKEPVFKASSIPGLENVEEWQ

Sequences:

>Translated_466_residues
MEILNNLVVSFNDFLWGYILIILLIGAGLLFSFKTKFVQFRYIKEMFRLLGDGIGKSNKEKGGVSSFQAFCISTASRVGT
GNIAGVAIAVAVGGPGAVFWMWLIALIGSASSFVESTLAQIYKTKDKDSFRGGPAYYMEKGLGKRWLGIIFSILITICFG
FVFNAVQANTVSVAFNSAFGLSRGAIGIILAIVTALVIFGGIHRVAKVSEIIVPILAVLYILIAIIVLILNITEIPSVFK
LIFESAFGIKQLTAGGLGAAVMQGIKRGLFSNEAGMGSAPNAAATADVTHPVKQGLIQTLGVFTDTLLICSCTAFIILLS
GQYADSSLTGIELTQKALVSQIGPFGAYFIAICILLFAFSSIVGNFYYGQTNIEFIHTNKVLLNIYRILVIGMVLFGSIA
KVDLVWNLADLFMGLMAILNIITILFLGKYSFLALKDYTAQKKAGIKEPVFKASSIPGLENVEEWQ
>Mature_466_residues
MEILNNLVVSFNDFLWGYILIILLIGAGLLFSFKTKFVQFRYIKEMFRLLGDGIGKSNKEKGGVSSFQAFCISTASRVGT
GNIAGVAIAVAVGGPGAVFWMWLIALIGSASSFVESTLAQIYKTKDKDSFRGGPAYYMEKGLGKRWLGIIFSILITICFG
FVFNAVQANTVSVAFNSAFGLSRGAIGIILAIVTALVIFGGIHRVAKVSEIIVPILAVLYILIAIIVLILNITEIPSVFK
LIFESAFGIKQLTAGGLGAAVMQGIKRGLFSNEAGMGSAPNAAATADVTHPVKQGLIQTLGVFTDTLLICSCTAFIILLS
GQYADSSLTGIELTQKALVSQIGPFGAYFIAICILLFAFSSIVGNFYYGQTNIEFIHTNKVLLNIYRILVIGMVLFGSIA
KVDLVWNLADLFMGLMAILNIITILFLGKYSFLALKDYTAQKKAGIKEPVFKASSIPGLENVEEWQ

Specific function: Probably functions as a sodium/glutamine symporter for glutamine uptake [H]

COG id: COG1115

COG function: function code E; Na+/alanine symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:alanine (SAF) symporter family [H]

Homologues:

Organism=Escherichia coli, GI1786188, Length=455, Percent_Identity=43.7362637362637, Blast_Score=370, Evalue=1e-104,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001463 [H]

Pfam domain/function: PF01235 Na_Ala_symp [H]

EC number: NA

Molecular weight: Translated: 50174; Mature: 50174

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: PS00873 NA_ALANINE_SYMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEILNNLVVSFNDFLWGYILIILLIGAGLLFSFKTKFVQFRYIKEMFRLLGDGIGKSNKE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
KGGVSSFQAFCISTASRVGTGNIAGVAIAVAVGGPGAVFWMWLIALIGSASSFVESTLAQ
CCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHH
IYKTKDKDSFRGGPAYYMEKGLGKRWLGIIFSILITICFGFVFNAVQANTVSVAFNSAFG
HHHCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCC
LSRGAIGIILAIVTALVIFGGIHRVAKVSEIIVPILAVLYILIAIIVLILNITEIPSVFK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIFESAFGIKQLTAGGLGAAVMQGIKRGLFSNEAGMGSAPNAAATADVTHPVKQGLIQTL
HHHHHHCCHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
GVFTDTLLICSCTAFIILLSGQYADSSLTGIELTQKALVSQIGPFGAYFIAICILLFAFS
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
SIVGNFYYGQTNIEFIHTNKVLLNIYRILVIGMVLFGSIAKVDLVWNLADLFMGLMAILN
HHHCCCEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IITILFLGKYSFLALKDYTAQKKAGIKEPVFKASSIPGLENVEEWQ
HHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCHHCCC
>Mature Secondary Structure
MEILNNLVVSFNDFLWGYILIILLIGAGLLFSFKTKFVQFRYIKEMFRLLGDGIGKSNKE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
KGGVSSFQAFCISTASRVGTGNIAGVAIAVAVGGPGAVFWMWLIALIGSASSFVESTLAQ
CCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHH
IYKTKDKDSFRGGPAYYMEKGLGKRWLGIIFSILITICFGFVFNAVQANTVSVAFNSAFG
HHHCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCC
LSRGAIGIILAIVTALVIFGGIHRVAKVSEIIVPILAVLYILIAIIVLILNITEIPSVFK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIFESAFGIKQLTAGGLGAAVMQGIKRGLFSNEAGMGSAPNAAATADVTHPVKQGLIQTL
HHHHHHCCHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
GVFTDTLLICSCTAFIILLSGQYADSSLTGIELTQKALVSQIGPFGAYFIAICILLFAFS
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
SIVGNFYYGQTNIEFIHTNKVLLNIYRILVIGMVLFGSIAKVDLVWNLADLFMGLMAILN
HHHCCCEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IITILFLGKYSFLALKDYTAQKKAGIKEPVFKASSIPGLENVEEWQ
HHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-alanine [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-alanine [Periplasm] = Na (I) [Cytoplasm] + L-alanine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]