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The map label for this gene is patA [H]

Identifier: 18310889

GI number: 18310889

Start: 2186304

End: 2187446

Strand: Reverse

Name: patA [H]

Synonym: CPE1907

Alternate gene names: 18310889

Gene position: 2187446-2186304 (Counterclockwise)

Preceding gene: 18310890

Following gene: 18310885

Centisome position: 72.16

GC content: 29.13

Gene sequence:

>1143_bases
ATGAATAAAAATGTTATTGGGATAGAAATATCAGGAATAAGAAAATTCTATAATGAAGTTGTAAAATTCCCAGAAGCTAT
ATCATTAACTCTAGGACAGCCAGATTTTCCTGTTCCAGAAAAAGTTAAAGAAGCTATGATAAGGGCTATTGAAGAAGGAA
AGACAACATATACAGCTAATGCTGGTATAGTTGAATTAAGAGAAGAAATATCAAGTTTATTAAAGAATAATTTTGATATT
GATTTTAGTAAGGATGAAATAATTATAACTGTAGGTGGAAGTGAAGGGCTATATGCAGCTATGACAGCCCTTTTAAATCC
TGGAGAGAAGGTTTTAGTTCCATCAATTGCATATCCAGCTTATGAGAGCATAAGTAAAATAATAGGGTGTGAAGTTATAA
ATTATGATTTAAATGAAGATTTTTCAGTTAATATAGAGAGTTTAAAAGAAGGAATAAAAGAAGGGGGAAAACTTTTAGTA
CTTTCTTATCCATGTAATCCTACTGGGGCATTACTTAGTAAAAAAAGTAGAGATGAGTTAATAGAGATTATAAAAGAAAA
TGATATATTAGTATTAACTGATGAAATTTATTCATCTCTATGCTTTGAAGAGGAGTATTATTCTGTAGCTCAATGCAAAG
ATATAAAAGAAAAAATAATATATGTAAGTGGATTCTCTAAGATGTTTTCAATGACAGGTCTTAGAATTGGATATGTAGCA
TGTCCTAAAAAAATATATGATCAAATTATAAAGGTTCATCAATACAATTCTTCATGTGCAACATCTATTTCTCAATGGGG
AGCCTTAGAAGGATTAAAATCTTGTATGAATGATGTTGAAAATATGAAAGAGTCTTTTAAAGAAAGAATGAATTTTACTT
ATAAAAGATTAAAAAGTATGGGATTAGAAGTGGAAAAACCTAAAGGAGCATTTTATATTTATCCTAATATAAGTAAGTTT
GGATTAACATCAGAAGAATTTTGTCATAGATTACTTAAAGAAGGCAAAGTTGCCTGTGTACCAGGAGATGCCTTTGGAAA
GGGTGGAGAAGGATACATTAGAATATCTTACTGTTATAGTAAAGATGAACTTGAAAGAGCCTTAGATAAATTAGAGGCTT
TTGTAAAAACTCTAAAAAAGTAA

Upstream 100 bases:

>100_bases
CAGAAAAAATAATGGAAAAAGCTGATCTAATAACAGAGATGAGAGAAATTAAGCATTATTATAAAAAAGGAGTTCCAGCT
AGAGAGGGGATAGAATTTTA

Downstream 100 bases:

>100_bases
ACTATGTTTTAAATAAAAGATAAATTAAAAAGGCAAAAATAAAATAAGTTATATAAAATCAAAAATAAAACTTATAAATA
GTATTAAGAGAAGAAAATAA

Product: asparate aminotransferase

Products: N-succinyl-2-L-amino-6-oxoheptanedioate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MNKNVIGIEISGIRKFYNEVVKFPEAISLTLGQPDFPVPEKVKEAMIRAIEEGKTTYTANAGIVELREEISSLLKNNFDI
DFSKDEIIITVGGSEGLYAAMTALLNPGEKVLVPSIAYPAYESISKIIGCEVINYDLNEDFSVNIESLKEGIKEGGKLLV
LSYPCNPTGALLSKKSRDELIEIIKENDILVLTDEIYSSLCFEEEYYSVAQCKDIKEKIIYVSGFSKMFSMTGLRIGYVA
CPKKIYDQIIKVHQYNSSCATSISQWGALEGLKSCMNDVENMKESFKERMNFTYKRLKSMGLEVEKPKGAFYIYPNISKF
GLTSEEFCHRLLKEGKVACVPGDAFGKGGEGYIRISYCYSKDELERALDKLEAFVKTLKK

Sequences:

>Translated_380_residues
MNKNVIGIEISGIRKFYNEVVKFPEAISLTLGQPDFPVPEKVKEAMIRAIEEGKTTYTANAGIVELREEISSLLKNNFDI
DFSKDEIIITVGGSEGLYAAMTALLNPGEKVLVPSIAYPAYESISKIIGCEVINYDLNEDFSVNIESLKEGIKEGGKLLV
LSYPCNPTGALLSKKSRDELIEIIKENDILVLTDEIYSSLCFEEEYYSVAQCKDIKEKIIYVSGFSKMFSMTGLRIGYVA
CPKKIYDQIIKVHQYNSSCATSISQWGALEGLKSCMNDVENMKESFKERMNFTYKRLKSMGLEVEKPKGAFYIYPNISKF
GLTSEEFCHRLLKEGKVACVPGDAFGKGGEGYIRISYCYSKDELERALDKLEAFVKTLKK
>Mature_380_residues
MNKNVIGIEISGIRKFYNEVVKFPEAISLTLGQPDFPVPEKVKEAMIRAIEEGKTTYTANAGIVELREEISSLLKNNFDI
DFSKDEIIITVGGSEGLYAAMTALLNPGEKVLVPSIAYPAYESISKIIGCEVINYDLNEDFSVNIESLKEGIKEGGKLLV
LSYPCNPTGALLSKKSRDELIEIIKENDILVLTDEIYSSLCFEEEYYSVAQCKDIKEKIIYVSGFSKMFSMTGLRIGYVA
CPKKIYDQIIKVHQYNSSCATSISQWGALEGLKSCMNDVENMKESFKERMNFTYKRLKSMGLEVEKPKGAFYIYPNISKF
GLTSEEFCHRLLKEGKVACVPGDAFGKGGEGYIRISYCYSKDELERALDKLEAFVKTLKK

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=341, Percent_Identity=26.099706744868, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI95147551, Length=419, Percent_Identity=23.8663484486874, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI169881279, Length=419, Percent_Identity=23.8663484486874, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI56713254, Length=400, Percent_Identity=22.75, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI56713256, Length=400, Percent_Identity=22.75, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI7705897, Length=414, Percent_Identity=24.6376811594203, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI33469970, Length=414, Percent_Identity=24.6376811594203, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI169881281, Length=405, Percent_Identity=22.2222222222222, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI19263340, Length=401, Percent_Identity=22.1945137157107, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI215599424, Length=401, Percent_Identity=22.1945137157107, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI149944424, Length=318, Percent_Identity=23.2704402515723, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1788722, Length=364, Percent_Identity=27.7472527472527, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1786816, Length=343, Percent_Identity=26.8221574344023, Blast_Score=148, Evalue=7e-37,
Organism=Escherichia coli, GI1788627, Length=369, Percent_Identity=26.0162601626016, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1790797, Length=357, Percent_Identity=22.4089635854342, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787710, Length=239, Percent_Identity=25.9414225941423, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17567663, Length=392, Percent_Identity=24.234693877551, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71994476, Length=394, Percent_Identity=23.3502538071066, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71994472, Length=394, Percent_Identity=23.3502538071066, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17567369, Length=390, Percent_Identity=23.0769230769231, Blast_Score=86, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6322401, Length=378, Percent_Identity=20.6349206349206, Blast_Score=94, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6320317, Length=349, Percent_Identity=22.0630372492837, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI18859735, Length=368, Percent_Identity=23.6413043478261, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI28573069, Length=387, Percent_Identity=23.2558139534884, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24646114, Length=387, Percent_Identity=23.2558139534884, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI28573067, Length=387, Percent_Identity=23.2558139534884, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI28573065, Length=387, Percent_Identity=23.2558139534884, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24641770, Length=397, Percent_Identity=24.4332493702771, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24641760, Length=397, Percent_Identity=24.4332493702771, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24641768, Length=397, Percent_Identity=24.4332493702771, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24641766, Length=397, Percent_Identity=24.4332493702771, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24641764, Length=397, Percent_Identity=24.4332493702771, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI45551451, Length=397, Percent_Identity=24.4332493702771, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI21356535, Length=331, Percent_Identity=24.1691842900302, Blast_Score=78, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.17

Molecular weight: Translated: 42626; Mature: 42626

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKNVIGIEISGIRKFYNEVVKFPEAISLTLGQPDFPVPEKVKEAMIRAIEEGKTTYTAN
CCCCEEEEEHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEECC
AGIVELREEISSLLKNNFDIDFSKDEIIITVGGSEGLYAAMTALLNPGEKVLVPSIAYPA
CCHHHHHHHHHHHHHCCCCCEECCCEEEEEECCCCCHHHHHHHHHCCCCEEEECCCCCHH
YESISKIIGCEVINYDLNEDFSVNIESLKEGIKEGGKLLVLSYPCNPTGALLSKKSRDEL
HHHHHHHHCCEEEEECCCCCCEEEHHHHHHHHHCCCEEEEEEECCCCHHHHHCCCCHHHH
IEIIKENDILVLTDEIYSSLCFEEEYYSVAQCKDIKEKIIYVSGFSKMFSMTGLRIGYVA
HHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHCCCEEEHEE
CPKKIYDQIIKVHQYNSSCATSISQWGALEGLKSCMNDVENMKESFKERMNFTYKRLKSM
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLEVEKPKGAFYIYPNISKFGLTSEEFCHRLLKEGKVACVPGDAFGKGGEGYIRISYCYS
CCEEECCCCCEEECCCCHHHCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCEEEEEEEEC
KDELERALDKLEAFVKTLKK
HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNKNVIGIEISGIRKFYNEVVKFPEAISLTLGQPDFPVPEKVKEAMIRAIEEGKTTYTAN
CCCCEEEEEHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEECC
AGIVELREEISSLLKNNFDIDFSKDEIIITVGGSEGLYAAMTALLNPGEKVLVPSIAYPA
CCHHHHHHHHHHHHHCCCCCEECCCEEEEEECCCCCHHHHHHHHHCCCCEEEECCCCCHH
YESISKIIGCEVINYDLNEDFSVNIESLKEGIKEGGKLLVLSYPCNPTGALLSKKSRDEL
HHHHHHHHCCEEEEECCCCCCEEEHHHHHHHHHCCCEEEEEEECCCCHHHHHCCCCHHHH
IEIIKENDILVLTDEIYSSLCFEEEYYSVAQCKDIKEKIIYVSGFSKMFSMTGLRIGYVA
HHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHCCCEEEHEE
CPKKIYDQIIKVHQYNSSCATSISQWGALEGLKSCMNDVENMKESFKERMNFTYKRLKSM
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLEVEKPKGAFYIYPNISKFGLTSEEFCHRLLKEGKVACVPGDAFGKGGEGYIRISYCYS
CCEEECCCCCEEECCCCHHHCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCEEEEEEEEC
KDELERALDKLEAFVKTLKK
HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-succinyl-L-2,6-diaminoheptanedioate; 2-oxoglutarate

Specific reaction: N-succinyl-L-2,6-diaminoheptanedioate + 2-oxoglutarate = N-succinyl-2-L-amino-6-oxoheptanedioate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 2104615 [H]