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The map label for this gene is btuR [H]

Identifier: 18310890

GI number: 18310890

Start: 2187446

End: 2187982

Strand: Reverse

Name: btuR [H]

Synonym: CPE1908

Alternate gene names: 18310890

Gene position: 2187982-2187446 (Counterclockwise)

Preceding gene: 18310892

Following gene: 18310889

Centisome position: 72.18

GC content: 32.77

Gene sequence:

>537_bases
ATGGCAAGACTTAAAGAAGGATATGTTCAAGTATATACTGGAAATGGAAAAGGAAAAACTACAGCAGCAATGGGATTAGC
TTTTAGAGCTGCAGGTGATGGCATGGAAGTAAAGGTGGTTCAATTCCTTAAATCATGGAAAACAGGTGAATTAGAATCTG
CTAAGAGATTTGATAACTTAGAGATATTAAGATTTGAAAAGGTTAAAGGATTTACTTGGGAATTAAATGAGGAAGAGTTA
GCTCAGTTAAAAGCAGAGGTTAGAGTAGGCTTTGATTTTGTAAAAGGACTAGTTGAAACTAGAGGATGTGATATATTAAT
TTTAGATGAGGTAATGGCTTCAATTTCTGGAGGGTTCATAGGAGAAGATGAAATTGTAGAATTAATCGAAAAGAAACCTA
AAGATATGGAATTAATTCTTACAGGAAGAAATGTACCAGAAAAAATAATGGAAAAAGCTGATCTAATAACAGAGATGAGA
GAAATTAAGCATTATTATAAAAAAGGAGTTCCAGCTAGAGAGGGGATAGAATTTTAA

Upstream 100 bases:

>100_bases
ATCAATAAAAGAGAAAAACGTAAAATTTATATTATTTAATAAATAGATTGTTTAAAAAATCAAATATATTATAAAATATA
ATTTAAAGGAGTGATAAAAT

Downstream 100 bases:

>100_bases
TGAATAAAAATGTTATTGGGATAGAAATATCAGGAATAAGAAAATTCTATAATGAAGTTGTAAAATTCCCAGAAGCTATA
TCATTAACTCTAGGACAGCC

Product: cob(I)alamin adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 178; Mature: 177

Protein sequence:

>178_residues
MARLKEGYVQVYTGNGKGKTTAAMGLAFRAAGDGMEVKVVQFLKSWKTGELESAKRFDNLEILRFEKVKGFTWELNEEEL
AQLKAEVRVGFDFVKGLVETRGCDILILDEVMASISGGFIGEDEIVELIEKKPKDMELILTGRNVPEKIMEKADLITEMR
EIKHYYKKGVPAREGIEF

Sequences:

>Translated_178_residues
MARLKEGYVQVYTGNGKGKTTAAMGLAFRAAGDGMEVKVVQFLKSWKTGELESAKRFDNLEILRFEKVKGFTWELNEEEL
AQLKAEVRVGFDFVKGLVETRGCDILILDEVMASISGGFIGEDEIVELIEKKPKDMELILTGRNVPEKIMEKADLITEMR
EIKHYYKKGVPAREGIEF
>Mature_177_residues
ARLKEGYVQVYTGNGKGKTTAAMGLAFRAAGDGMEVKVVQFLKSWKTGELESAKRFDNLEILRFEKVKGFTWELNEEELA
QLKAEVRVGFDFVKGLVETRGCDILILDEVMASISGGFIGEDEIVELIEKKPKDMELILTGRNVPEKIMEKADLITEMRE
IKHYYKKGVPAREGIEF

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=179, Percent_Identity=34.6368715083799, Blast_Score=108, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 20113; Mature: 19981

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARLKEGYVQVYTGNGKGKTTAAMGLAFRAAGDGMEVKVVQFLKSWKTGELESAKRFDNL
CCCCCCCEEEEEECCCCCCHHHHHHHHHEECCCCCHHHHHHHHHCCCCCCCCHHHHCCCE
EILRFEKVKGFTWELNEEELAQLKAEVRVGFDFVKGLVETRGCDILILDEVMASISGGFI
EEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCC
GEDEIVELIEKKPKDMELILTGRNVPEKIMEKADLITEMREIKHYYKKGVPAREGIEF
CHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
ARLKEGYVQVYTGNGKGKTTAAMGLAFRAAGDGMEVKVVQFLKSWKTGELESAKRFDNL
CCCCCCEEEEEECCCCCCHHHHHHHHHEECCCCCHHHHHHHHHCCCCCCCCHHHHCCCE
EILRFEKVKGFTWELNEEELAQLKAEVRVGFDFVKGLVETRGCDILILDEVMASISGGFI
EEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCC
GEDEIVELIEKKPKDMELILTGRNVPEKIMEKADLITEMREIKHYYKKGVPAREGIEF
CHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]