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The map label for this gene is xerD [H]

Identifier: 18310790

GI number: 18310790

Start: 2088169

End: 2089041

Strand: Reverse

Name: xerD [H]

Synonym: CPE1808

Alternate gene names: 18310790

Gene position: 2089041-2088169 (Counterclockwise)

Preceding gene: 18310791

Following gene: 18310789

Centisome position: 68.91

GC content: 28.98

Gene sequence:

>873_bases
ATGAAAGATTTAGTAAGCAAATACGAAGTATATCTAGAATCAATAGGCAAGAGAAAGAATACCGTAAGTGCATACATTAC
AGATGTCTCTATGTATTTAGATTTTGTAGAGGAAAAAGGGTTTAAGGTAAGTGAGGATTCATATCCTTTAATATCTTATG
TACAACATCTAAAAGAGAGCCACAAGTCTCCATCATCAATTCAAAGAACAATCATCTCTTTAAGAAATTTTTATAATTTC
TTAGTAGCAGAAGAATTTTTAAAGAAGGTTCCAAATTTAACTATGAAAAAAGAAAGAGTTGAAAAGAAAAAACCTTTAGT
TTTAACTGTTGAAGAGATAAATAAAATAATGAACTCTACTAATGTTTTAACTGAAAAGGGAATACGCGATAAGGCTTTAT
TAGAACTTATGTATGCTACTGGAATGAAAGTTTCAGAGTTAATATCTTTAAGAATTGAAGATATTAATTTAGATTCATCT
TTTGTAAATTGTAGAGATAGTAGAGGGTATGAGAGACTTATACCAATAGGAAAAGCAGCTAAGGAATCTCTTAAAAGATA
TATTGTGGTAAGAGAAGATAATTCTAAAGGATCAGATAAGCTTTTCTTAAATATGAGTGGAGAACCTATAACTAGGCAAG
GAGTTTGGAGAATTGTTAAGGAGTATGCTGTTATTGCAAATATTGGGAAGGATATAAATTTAAATACCTTTAGACATTCT
TTTGCAGTGCATTTATTACAAAACGGAGCAAATGCTAAGGTAGTACAAGAACTATTAGGAAATCAAGTTATGACTTATAT
AGATATGTACTATGATATTATAAACAATGAAAAAATTAACAATATATACAGAAAGGCTCATCCAAGAGCATAA

Upstream 100 bases:

>100_bases
ATTGAAACATATATATCACCTAATTTAATAAGATTAGTAATTAGTAGGTGATTTCTGTAATATAAATAATTATGTAATAA
CATTTTGGTTAGGAGTTAAT

Downstream 100 bases:

>100_bases
TATATAAAAGAAAAGGCTTTCATAAAAGTCTTTTCTTTTTATAATTTTTAGCTTTAAAATATTAGAATTTATCAAAAAAT
ACATAAAAATAATTTGAATT

Product: tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MKDLVSKYEVYLESIGKRKNTVSAYITDVSMYLDFVEEKGFKVSEDSYPLISYVQHLKESHKSPSSIQRTIISLRNFYNF
LVAEEFLKKVPNLTMKKERVEKKKPLVLTVEEINKIMNSTNVLTEKGIRDKALLELMYATGMKVSELISLRIEDINLDSS
FVNCRDSRGYERLIPIGKAAKESLKRYIVVREDNSKGSDKLFLNMSGEPITRQGVWRIVKEYAVIANIGKDINLNTFRHS
FAVHLLQNGANAKVVQELLGNQVMTYIDMYYDIINNEKINNIYRKAHPRA

Sequences:

>Translated_290_residues
MKDLVSKYEVYLESIGKRKNTVSAYITDVSMYLDFVEEKGFKVSEDSYPLISYVQHLKESHKSPSSIQRTIISLRNFYNF
LVAEEFLKKVPNLTMKKERVEKKKPLVLTVEEINKIMNSTNVLTEKGIRDKALLELMYATGMKVSELISLRIEDINLDSS
FVNCRDSRGYERLIPIGKAAKESLKRYIVVREDNSKGSDKLFLNMSGEPITRQGVWRIVKEYAVIANIGKDINLNTFRHS
FAVHLLQNGANAKVVQELLGNQVMTYIDMYYDIINNEKINNIYRKAHPRA
>Mature_290_residues
MKDLVSKYEVYLESIGKRKNTVSAYITDVSMYLDFVEEKGFKVSEDSYPLISYVQHLKESHKSPSSIQRTIISLRNFYNF
LVAEEFLKKVPNLTMKKERVEKKKPLVLTVEEINKIMNSTNVLTEKGIRDKALLELMYATGMKVSELISLRIEDINLDSS
FVNCRDSRGYERLIPIGKAAKESLKRYIVVREDNSKGSDKLFLNMSGEPITRQGVWRIVKEYAVIANIGKDINLNTFRHS
FAVHLLQNGANAKVVQELLGNQVMTYIDMYYDIINNEKINNIYRKAHPRA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=302, Percent_Identity=29.8013245033113, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI1790244, Length=296, Percent_Identity=25.3378378378378, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1790768, Length=163, Percent_Identity=27.6073619631902, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790767, Length=195, Percent_Identity=25.1282051282051, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33460; Mature: 33460

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDLVSKYEVYLESIGKRKNTVSAYITDVSMYLDFVEEKGFKVSEDSYPLISYVQHLKES
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHH
HKSPSSIQRTIISLRNFYNFLVAEEFLKKVPNLTMKKERVEKKKPLVLTVEEINKIMNST
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEEHHHHHHHHHHH
NVLTEKGIRDKALLELMYATGMKVSELISLRIEDINLDSSFVNCRDSRGYERLIPIGKAA
HHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHCCCCCCCHHHHCCCCHHH
KESLKRYIVVREDNSKGSDKLFLNMSGEPITRQGVWRIVKEYAVIANIGKDINLNTFRHS
HHHHHHEEEEEECCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
FAVHLLQNGANAKVVQELLGNQVMTYIDMYYDIINNEKINNIYRKAHPRA
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCC
>Mature Secondary Structure
MKDLVSKYEVYLESIGKRKNTVSAYITDVSMYLDFVEEKGFKVSEDSYPLISYVQHLKES
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHH
HKSPSSIQRTIISLRNFYNFLVAEEFLKKVPNLTMKKERVEKKKPLVLTVEEINKIMNST
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEEHHHHHHHHHHH
NVLTEKGIRDKALLELMYATGMKVSELISLRIEDINLDSSFVNCRDSRGYERLIPIGKAA
HHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHCCCCCCCHHHHCCCCHHH
KESLKRYIVVREDNSKGSDKLFLNMSGEPITRQGVWRIVKEYAVIANIGKDINLNTFRHS
HHHHHHEEEEEECCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
FAVHLLQNGANAKVVQELLGNQVMTYIDMYYDIINNEKINNIYRKAHPRA
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]