Click here to switch to the map view.

The map label for this gene is tagO [H]

Identifier: 18310616

GI number: 18310616

Start: 1906533

End: 1907492

Strand: Reverse

Name: tagO [H]

Synonym: CPE1634

Alternate gene names: 18310616

Gene position: 1907492-1906533 (Counterclockwise)

Preceding gene: 18310617

Following gene: 18310615

Centisome position: 62.92

GC content: 30.73

Gene sequence:

>960_bases
ATGATTAAGTATTTAATTGTAATGCTTATTCCTTTTGTCATAGTATATCTATTAATGCCAAAGTTTATTGAATTTGCAAA
TGAAAAGGGTTTTGTTGATAAGCCTACAGGAAGAAAAAAACATGATAAATTAACACCTTTAATAGGTGGGGTTGTTATGT
ATATAGGATTTTTTGCAACATACCTTTTTGGAATAGATTCTACAAGGCAATTATCACAAACTTTTATTATATTTATAGCA
GCTACTTTGGTAATAATAATAGGAGTGATTGATGACTATTATAAGGGAAAGGGCAAAGAGTTTCCGATTTATCCAAGAGT
TATAATTCAAATTTTAGCTGCAACTATGGTTTTTAAAGCTGGGATTGTTTTTAGGGGTATAACTAATCCATTTACTGGAG
AGTTTACTCAATTTTCAGGATGGATTCAATATATACTTACAATAACATGGATTTTTGGGGGTACTACAGTAATAAACTGG
TCTGATGGAATGGATGGATTAGCAGGAAGCATTTCCATAATATCTGCTATGACTATGTTTGTTGTTGCTCTTGCAAAAGG
ACAATTTAACTCTGCATATATGTCAATAACTCTAGTAGGGTCAATATTAGCCTTTTTAAGATATAATAGACATCCAGCGC
GAGTATTTATGGGTGATTCAGGTGCTAACTTTTTAGGGTTTATTTTAGCTATTATAGCCTTAGAAGGTGCTTTTAAGCAA
GCACCAGCATTATCTATATTAGTGCCAGTATTAGCCTTAGGAGTTCCTATTTTTGATAATATCTTTGTAATTTTTAGAAG
ATTTCAATCTGGAAAGCCTGTTTATGAAGCTGATAGAAGCCAAATACATTATAGGCTACAAGAAAGAGGAATGTCTGTAA
AGCAAATTGTGTCATATATATGCATACTAAGTGGATGTTTAAGTTTAGTATCATTATTAATAATTATGATAATATTATAA

Upstream 100 bases:

>100_bases
GTGATAAAATAATTTTAATTAAAATGTCATTAATATGACTTATTAATCTACTAGAATAGTATATGTAAGAAAAAATGTTT
TTAATACAGAGGGAGAAAAA

Downstream 100 bases:

>100_bases
GTATTGACTGTCTTTAAAGTATAATAAGTTTTAACTTAGATGCTTTAAAGACAGTCAATAATATTTTACAGAGAATATAA
TATATAATTTATTAGTGAAA

Product: undecaprenyl-phosphate N-acetylglucosaminyltransferase

Products: UMP; Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

Alternate protein names: UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; Undecaprenyl-Phosphate GlcNAc-1-phosphate transferase [H]

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MIKYLIVMLIPFVIVYLLMPKFIEFANEKGFVDKPTGRKKHDKLTPLIGGVVMYIGFFATYLFGIDSTRQLSQTFIIFIA
ATLVIIIGVIDDYYKGKGKEFPIYPRVIIQILAATMVFKAGIVFRGITNPFTGEFTQFSGWIQYILTITWIFGGTTVINW
SDGMDGLAGSISIISAMTMFVVALAKGQFNSAYMSITLVGSILAFLRYNRHPARVFMGDSGANFLGFILAIIALEGAFKQ
APALSILVPVLALGVPIFDNIFVIFRRFQSGKPVYEADRSQIHYRLQERGMSVKQIVSYICILSGCLSLVSLLIIMIIL

Sequences:

>Translated_319_residues
MIKYLIVMLIPFVIVYLLMPKFIEFANEKGFVDKPTGRKKHDKLTPLIGGVVMYIGFFATYLFGIDSTRQLSQTFIIFIA
ATLVIIIGVIDDYYKGKGKEFPIYPRVIIQILAATMVFKAGIVFRGITNPFTGEFTQFSGWIQYILTITWIFGGTTVINW
SDGMDGLAGSISIISAMTMFVVALAKGQFNSAYMSITLVGSILAFLRYNRHPARVFMGDSGANFLGFILAIIALEGAFKQ
APALSILVPVLALGVPIFDNIFVIFRRFQSGKPVYEADRSQIHYRLQERGMSVKQIVSYICILSGCLSLVSLLIIMIIL
>Mature_319_residues
MIKYLIVMLIPFVIVYLLMPKFIEFANEKGFVDKPTGRKKHDKLTPLIGGVVMYIGFFATYLFGIDSTRQLSQTFIIFIA
ATLVIIIGVIDDYYKGKGKEFPIYPRVIIQILAATMVFKAGIVFRGITNPFTGEFTQFSGWIQYILTITWIFGGTTVINW
SDGMDGLAGSISIISAMTMFVVALAKGQFNSAYMSITLVGSILAFLRYNRHPARVFMGDSGANFLGFILAIIALEGAFKQ
APALSILVPVLALGVPIFDNIFVIFRRFQSGKPVYEADRSQIHYRLQERGMSVKQIVSYICILSGCLSLVSLLIIMIIL

Specific function: Catalyzes the formation of undecaprenyl-PP-N- acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to t

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family [H]

Homologues:

Organism=Escherichia coli, GI1790218, Length=276, Percent_Identity=25.7246376811594, Blast_Score=108, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: 2.7.8.- [C]

Molecular weight: Translated: 35502; Mature: 35502

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKYLIVMLIPFVIVYLLMPKFIEFANEKGFVDKPTGRKKHDKLTPLIGGVVMYIGFFAT
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
YLFGIDSTRQLSQTFIIFIAATLVIIIGVIDDYYKGKGKEFPIYPRVIIQILAATMVFKA
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
GIVFRGITNPFTGEFTQFSGWIQYILTITWIFGGTTVINWSDGMDGLAGSISIISAMTMF
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHH
VVALAKGQFNSAYMSITLVGSILAFLRYNRHPARVFMGDSGANFLGFILAIIALEGAFKQ
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHH
APALSILVPVLALGVPIFDNIFVIFRRFQSGKPVYEADRSQIHYRLQERGMSVKQIVSYI
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
CILSGCLSLVSLLIIMIIL
HHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MIKYLIVMLIPFVIVYLLMPKFIEFANEKGFVDKPTGRKKHDKLTPLIGGVVMYIGFFAT
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
YLFGIDSTRQLSQTFIIFIAATLVIIIGVIDDYYKGKGKEFPIYPRVIIQILAATMVFKA
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
GIVFRGITNPFTGEFTQFSGWIQYILTITWIFGGTTVINWSDGMDGLAGSISIISAMTMF
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHH
VVALAKGQFNSAYMSITLVGSILAFLRYNRHPARVFMGDSGANFLGFILAIIALEGAFKQ
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHH
APALSILVPVLALGVPIFDNIFVIFRRFQSGKPVYEADRSQIHYRLQERGMSVKQIVSYI
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
CILSGCLSLVSLLIIMIIL
HHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-Acetyl-D-Glucosamine; Undecaprenyl Phosphate [C]

Specific reaction: UDP-N-Acetyl-D-Glucosamine + Undecaprenyl Phosphate = UMP + Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12101296; 9384377 [H]