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The map label for this gene is xpt

Identifier: 18310274

GI number: 18310274

Start: 1526730

End: 1527308

Strand: Reverse

Name: xpt

Synonym: CPE1292

Alternate gene names: 18310274

Gene position: 1527308-1526730 (Counterclockwise)

Preceding gene: 18310276

Following gene: 18310273

Centisome position: 50.38

GC content: 28.32

Gene sequence:

>579_bases
ATGGAACTATTAAAAGATAAGATAAAAAAAGAAGGTAGAGTTACAGAAGATAATATTTTAATGGTTGATTCTTTTTTAAA
TCACCAAATGGATGTAGAATTTTTTAACGAAGTAGGAAAAGAATTTAAAGATAGATTTAAAAATGATCAAATAGACAAAA
TCCTTACAATAGAATCAACAGGAATAGGATTAGGAATAATAACTGCTCAATACTTTGATAATGTACCAGTTGTTTTTGGT
AAGAAAATAGAAAGATTACCAAGAAACAAGAGAGAAGAGGTATTTAATTCAGAAGTTTATTCATTCACTAAAAAAACAAT
ATACAATGTTGTTGTTGATAAGAAATTCATAAAACCAGGAGAAAAAATCCTTATAGTTGATGATTTCTTAGCAAATGCCT
GTGCAGTTTTTGGATTAATAGATGTTGTTAAACAAGCTGGAGCAGAAGTTGTTGGAGTAGGAATAGTTATAGAAAAAGGA
TTCCAAAGCGGAAGAGCTCACTTAGAAGACAAAGGAATAAGAGTTGAATCTCTAGTTACTATAGATAAGATAGAAGATGG
AGAAGTTTACTTTAAATAA

Upstream 100 bases:

>100_bases
GAATACTGTATAATAAAATTAGATAGCAATAGGTTTTCCTATTATGATATAATATAGGAAGTTAATACTATAAATTAATA
GTAAGAAAGGATGTAACCAA

Downstream 100 bases:

>100_bases
TTTTTTTAAGATTATTTTTATTAGCTAAATAGGGCTAAAAAGTAACATTTTAAGCCTGAAGAGAGCAAAAGATAAGAAAT
TTTAATTTAGGTAAAATTAA

Product: xanthine phosphoribosyltransferase

Products: NA

Alternate protein names: XPRTase 2

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MELLKDKIKKEGRVTEDNILMVDSFLNHQMDVEFFNEVGKEFKDRFKNDQIDKILTIESTGIGLGIITAQYFDNVPVVFG
KKIERLPRNKREEVFNSEVYSFTKKTIYNVVVDKKFIKPGEKILIVDDFLANACAVFGLIDVVKQAGAEVVGVGIVIEKG
FQSGRAHLEDKGIRVESLVTIDKIEDGEVYFK

Sequences:

>Translated_192_residues
MELLKDKIKKEGRVTEDNILMVDSFLNHQMDVEFFNEVGKEFKDRFKNDQIDKILTIESTGIGLGIITAQYFDNVPVVFG
KKIERLPRNKREEVFNSEVYSFTKKTIYNVVVDKKFIKPGEKILIVDDFLANACAVFGLIDVVKQAGAEVVGVGIVIEKG
FQSGRAHLEDKGIRVESLVTIDKIEDGEVYFK
>Mature_192_residues
MELLKDKIKKEGRVTEDNILMVDSFLNHQMDVEFFNEVGKEFKDRFKNDQIDKILTIESTGIGLGIITAQYFDNVPVVFG
KKIERLPRNKREEVFNSEVYSFTKKTIYNVVVDKKFIKPGEKILIVDDFLANACAVFGLIDVVKQAGAEVVGVGIVIEKG
FQSGRAHLEDKGIRVESLVTIDKIEDGEVYFK

Specific function: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XPT subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XPT2_CLOP1 (Q0TQZ9)

Other databases:

- EMBL:   CP000246
- RefSeq:   YP_695941.1
- ProteinModelPortal:   Q0TQZ9
- SMR:   Q0TQZ9
- STRING:   Q0TQZ9
- GeneID:   4202594
- GenomeReviews:   CP000246_GR
- KEGG:   cpf:CPF_1498
- TIGR:   CPF_1498
- eggNOG:   COG0503
- HOGENOM:   HBG288993
- OMA:   MIAIINA
- ProtClustDB:   PRK09219
- BioCyc:   CPER195103:CPF_1498-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01184
- InterPro:   IPR000836
- InterPro:   IPR010079
- TIGRFAMs:   TIGR01744

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.22

Molecular weight: Translated: 21796; Mature: 21796

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: BINDING 20-20 BINDING 27-27 BINDING 159-159

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELLKDKIKKEGRVTEDNILMVDSFLNHQMDVEFFNEVGKEFKDRFKNDQIDKILTIEST
CCHHHHHHHHCCCCCCCCEEEEEHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECC
GIGLGIITAQYFDNVPVVFGKKIERLPRNKREEVFNSEVYSFTKKTIYNVVVDKKFIKPG
CCCCCEEEHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EKILIVDDFLANACAVFGLIDVVKQAGAEVVGVGIVIEKGFQSGRAHLEDKGIRVESLVT
CEEEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCHHCCCEEEEHEEE
IDKIEDGEVYFK
EECCCCCCEEEC
>Mature Secondary Structure
MELLKDKIKKEGRVTEDNILMVDSFLNHQMDVEFFNEVGKEFKDRFKNDQIDKILTIEST
CCHHHHHHHHCCCCCCCCEEEEEHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECC
GIGLGIITAQYFDNVPVVFGKKIERLPRNKREEVFNSEVYSFTKKTIYNVVVDKKFIKPG
CCCCCEEEHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EKILIVDDFLANACAVFGLIDVVKQAGAEVVGVGIVIEKGFQSGRAHLEDKGIRVESLVT
CEEEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCHHCCCEEEEHEEE
IDKIEDGEVYFK
EECCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA