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The map label for this gene is sod [H]

Identifier: 18310218

GI number: 18310218

Start: 1443783

End: 1444466

Strand: Reverse

Name: sod [H]

Synonym: CPE1236

Alternate gene names: 18310218

Gene position: 1444466-1443783 (Counterclockwise)

Preceding gene: 18310219

Following gene: 18310217

Centisome position: 47.65

GC content: 30.41

Gene sequence:

>684_bases
ATGAAAAATAATTTTTTAAAACACAAAAAAAGTCCATTAATGTATCCAGCTTACTGTGGATCATCTTCAACTAAAGGGGA
AGGTTTTAAATTAAAACCTTTAGATTATCCTTATGATGCTTTAGAGCCATCAATAGATGCAGAAACAGTAAAAATTCATC
ATGACAAACATCAACAAGCTTATGTAGATAAGTTAAATAAAGCTTTAGAAAAACATCCTGAGCTTTATGGCAAAAGCTTA
TACGATATTTTAAGCAATTTAGATGATATGCCAGAGGATATTATGGCTGATTTAGTAAATCAAGGTGGTGGAGTTTATAA
CCATGAATTCTACTGGAGCATTTTAGGAAAAGGATGTAATAGACCAGTTGCTGAAATAGCAGATGCTATAGACAGAGATT
TTGGTTCTTTTGAAGAATTCAAAGAAAAGTTTAAACAATGTGGAATCTCTACCTTTGGTTCAGGTTGGGCATGGTTAGTT
AGTGATAAAGATGGAAAGTTAGAAATCATGTCAACTAAGGATCAATCATCTCCTATTTCTTTAGGATTAATTCCTATATT
AACAATGGATGTTTGGGAACATGCTTATTATTTAAAATATCAAAATAGACGTCCAGAGTATATAGACTATTTCTTCGATA
TAATAAACTGGAAAAAGTGTGAAGAATATTATAACAATAGATAA

Upstream 100 bases:

>100_bases
AAAACTTTGATTTTACAAAGTATTAAATTAAAAAAATAAATATAAAAATAGGTATTGGGAAGAATAATAATAAATTATTT
CAAATATGAGGAGGTAAAAA

Downstream 100 bases:

>100_bases
TAGAAAAATATTATAAAATATGTAATAAATCATAGAAAGAGCGTGTATTAAAGTGGTTTTTAAATAAAATTTACTTTAAT
ACACGCTTTTTAAAATATTA

Product: Mn/Fe superoxide dismutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MKNNFLKHKKSPLMYPAYCGSSSTKGEGFKLKPLDYPYDALEPSIDAETVKIHHDKHQQAYVDKLNKALEKHPELYGKSL
YDILSNLDDMPEDIMADLVNQGGGVYNHEFYWSILGKGCNRPVAEIADAIDRDFGSFEEFKEKFKQCGISTFGSGWAWLV
SDKDGKLEIMSTKDQSSPISLGLIPILTMDVWEHAYYLKYQNRRPEYIDYFFDIINWKKCEEYYNNR

Sequences:

>Translated_227_residues
MKNNFLKHKKSPLMYPAYCGSSSTKGEGFKLKPLDYPYDALEPSIDAETVKIHHDKHQQAYVDKLNKALEKHPELYGKSL
YDILSNLDDMPEDIMADLVNQGGGVYNHEFYWSILGKGCNRPVAEIADAIDRDFGSFEEFKEKFKQCGISTFGSGWAWLV
SDKDGKLEIMSTKDQSSPISLGLIPILTMDVWEHAYYLKYQNRRPEYIDYFFDIINWKKCEEYYNNR
>Mature_227_residues
MKNNFLKHKKSPLMYPAYCGSSSTKGEGFKLKPLDYPYDALEPSIDAETVKIHHDKHQQAYVDKLNKALEKHPELYGKSL
YDILSNLDDMPEDIMADLVNQGGGVYNHEFYWSILGKGCNRPVAEIADAIDRDFGSFEEFKEKFKQCGISTFGSGWAWLV
SDKDGKLEIMSTKDQSSPISLGLIPILTMDVWEHAYYLKYQNRRPEYIDYFFDIINWKKCEEYYNNR

Specific function: Destroys radicals which are normally produced within the cells and which are toxic to biological systems [H]

COG id: COG0605

COG function: function code P; Superoxide dismutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron/manganese superoxide dismutase family [H]

Homologues:

Organism=Homo sapiens, GI67782307, Length=225, Percent_Identity=39.1111111111111, Blast_Score=156, Evalue=2e-38,
Organism=Homo sapiens, GI67782305, Length=225, Percent_Identity=39.1111111111111, Blast_Score=156, Evalue=2e-38,
Organism=Homo sapiens, GI67782309, Length=224, Percent_Identity=34.8214285714286, Blast_Score=126, Evalue=1e-29,
Organism=Escherichia coli, GI1790342, Length=202, Percent_Identity=44.5544554455446, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1787946, Length=191, Percent_Identity=42.9319371727749, Blast_Score=171, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI17569479, Length=196, Percent_Identity=37.2448979591837, Blast_Score=135, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17506561, Length=196, Percent_Identity=36.734693877551, Blast_Score=135, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6321796, Length=217, Percent_Identity=30.8755760368664, Blast_Score=119, Evalue=5e-28,
Organism=Drosophila melanogaster, GI17136812, Length=189, Percent_Identity=40.2116402116402, Blast_Score=135, Evalue=2e-32,

Paralogues:

None

Copy number: 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001189
- InterPro:   IPR019833
- InterPro:   IPR019832
- InterPro:   IPR019831 [H]

Pfam domain/function: PF02777 Sod_Fe_C; PF00081 Sod_Fe_N [H]

EC number: =1.15.1.1 [H]

Molecular weight: Translated: 26343; Mature: 26343

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS00088 SOD_MN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNNFLKHKKSPLMYPAYCGSSSTKGEGFKLKPLDYPYDALEPSIDAETVKIHHDKHQQA
CCCCCCCCCCCCCCEEEECCCCCCCCCCEEECCCCCCHHHCCCCCCCCEEEEECCHHHHH
YVDKLNKALEKHPELYGKSLYDILSNLDDMPEDIMADLVNQGGGVYNHEFYWSILGKGCN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCC
RPVAEIADAIDRDFGSFEEFKEKFKQCGISTFGSGWAWLVSDKDGKLEIMSTKDQSSPIS
CCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEECCCCCCCEE
LGLIPILTMDVWEHAYYLKYQNRRPEYIDYFFDIINWKKCEEYYNNR
EHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKNNFLKHKKSPLMYPAYCGSSSTKGEGFKLKPLDYPYDALEPSIDAETVKIHHDKHQQA
CCCCCCCCCCCCCCEEEECCCCCCCCCCEEECCCCCCHHHCCCCCCCCEEEEECCHHHHH
YVDKLNKALEKHPELYGKSLYDILSNLDDMPEDIMADLVNQGGGVYNHEFYWSILGKGCN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCC
RPVAEIADAIDRDFGSFEEFKEKFKQCGISTFGSGWAWLVSDKDGKLEIMSTKDQSSPIS
CCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEECCCCCCCEE
LGLIPILTMDVWEHAYYLKYQNRRPEYIDYFFDIINWKKCEEYYNNR
EHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1624106 [H]