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The map label for this gene is hisB [H]

Identifier: 18310038

GI number: 18310038

Start: 1262188

End: 1263012

Strand: Direct

Name: hisB [H]

Synonym: CPE1056

Alternate gene names: 18310038

Gene position: 1262188-1263012 (Clockwise)

Preceding gene: 18310037

Following gene: 18310041

Centisome position: 41.64

GC content: 30.18

Gene sequence:

>825_bases
ATGATTTTAAACACAAAAAGAGATGGACATGTTCATAGTACTTATTGCCCACATGGTAGCAATGATACTCTAGATATGTA
CATTGATACTGCATTAAAAAATGGGATTACAGAAATAACTTTTACAGAACATATGCCACTACCTATGGAAGACCCTTCAC
CAAGAAAAAACAGTGCTTTACCTATGGAAAGATTAGAGGAGTACATAAAAGGAATAACTGAGCTAAAAGAAAAGGTTAAG
GATAAAATTAAAGTTAATCTAGGCTTAGAGGTTGATTATGTGGAAGGGTATGAAGAAGAGACTAAAGCTATATTAAATAA
ATATGGAAAATATTTAGATGATGCAATTCTTTCAGTTCATATAGTGAAGTTTCAAGGAGAGTATTACCAAATAGGTAATG
GATCAGATATGATTGGTGAATTAGTAGAGAAAATTGGCGGAATGGACAAGCTTTATGATCTATACTATGAAACTATGTTA
AAGTCAATTAAATGCGATCTAGGAGCCTTTAAACCTAAAAGAATAGGACATCCAACTTTAGTTAGAAAGTATAAAGCAGA
TTTTCCTAATGAAAAATATAATATTAAGCTTTTAGAGAGTATTCTAAAAGAAATGAAAAAAGGAAATTATGAAATTGATT
TAAATACTTCAGGTCTTAGAAGAGAGAAATGTGGAGAGGTACATCCTCAAGGAATATTTTTAGATTTATGTTTAAAGTAT
AATATACCTATGGTATTAGGATCTGATTCTCATAGTTCAAAATATGTTGGAGTAGAGTTTGAGAAGGTTGCAAATATGAT
TTTTCCAGATTCAGAAGCAATATAA

Upstream 100 bases:

>100_bases
GTTTATTTTTAGAGTTTTTAATTTTTTAAATCTAAGTTAATCTTTTTATTAAGATTTTAGATTTTGACAAAATTTATAGC
AGCATAATACGGAGGATAAA

Downstream 100 bases:

>100_bases
AAGACACTATAACTTATATAAATTTATTGAAAAATTTGTATGAGAAGAGATTTTAAAATAATTATCTATAAAGTTTTAAT
TTATAGATAATAAAAAAGCA

Product: histidinol-phosphatase

Products: NA

Alternate protein names: HolPase [H]

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MILNTKRDGHVHSTYCPHGSNDTLDMYIDTALKNGITEITFTEHMPLPMEDPSPRKNSALPMERLEEYIKGITELKEKVK
DKIKVNLGLEVDYVEGYEEETKAILNKYGKYLDDAILSVHIVKFQGEYYQIGNGSDMIGELVEKIGGMDKLYDLYYETML
KSIKCDLGAFKPKRIGHPTLVRKYKADFPNEKYNIKLLESILKEMKKGNYEIDLNTSGLRREKCGEVHPQGIFLDLCLKY
NIPMVLGSDSHSSKYVGVEFEKVANMIFPDSEAI

Sequences:

>Translated_274_residues
MILNTKRDGHVHSTYCPHGSNDTLDMYIDTALKNGITEITFTEHMPLPMEDPSPRKNSALPMERLEEYIKGITELKEKVK
DKIKVNLGLEVDYVEGYEEETKAILNKYGKYLDDAILSVHIVKFQGEYYQIGNGSDMIGELVEKIGGMDKLYDLYYETML
KSIKCDLGAFKPKRIGHPTLVRKYKADFPNEKYNIKLLESILKEMKKGNYEIDLNTSGLRREKCGEVHPQGIFLDLCLKY
NIPMVLGSDSHSSKYVGVEFEKVANMIFPDSEAI
>Mature_274_residues
MILNTKRDGHVHSTYCPHGSNDTLDMYIDTALKNGITEITFTEHMPLPMEDPSPRKNSALPMERLEEYIKGITELKEKVK
DKIKVNLGLEVDYVEGYEEETKAILNKYGKYLDDAILSVHIVKFQGEYYQIGNGSDMIGELVEKIGGMDKLYDLYYETML
KSIKCDLGAFKPKRIGHPTLVRKYKADFPNEKYNIKLLESILKEMKKGNYEIDLNTSGLRREKCGEVHPQGIFLDLCLKY
NIPMVLGSDSHSSKYVGVEFEKVANMIFPDSEAI

Specific function: Unknown

COG id: COG1387

COG function: function code ER; Histidinol phosphatase and related hydrolases of the PHP family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHP hydrolase family. HisK subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010140
- InterPro:   IPR004013
- InterPro:   IPR016195 [H]

Pfam domain/function: PF02811 PHP [H]

EC number: =3.1.3.15 [H]

Molecular weight: Translated: 31307; Mature: 31307

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILNTKRDGHVHSTYCPHGSNDTLDMYIDTALKNGITEITFTEHMPLPMEDPSPRKNSAL
CCCCCCCCCCEECCCCCCCCCCCHHHEEHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCC
PMERLEEYIKGITELKEKVKDKIKVNLGLEVDYVEGYEEETKAILNKYGKYLDDAILSVH
CHHHHHHHHHHHHHHHHHHHHHEEEECCEEEEHHCCCHHHHHHHHHHHHHHHHHHHHEEE
IVKFQGEYYQIGNGSDMIGELVEKIGGMDKLYDLYYETMLKSIKCDLGAFKPKRIGHPTL
EEEECCCEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
VRKYKADFPNEKYNIKLLESILKEMKKGNYEIDLNTSGLRREKCGEVHPQGIFLDLCLKY
HHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHCCCCCCCCEEEEEHHHC
NIPMVLGSDSHSSKYVGVEFEKVANMIFPDSEAI
CCCEEECCCCCCCCEECEEHHHHHHHHCCCCCCC
>Mature Secondary Structure
MILNTKRDGHVHSTYCPHGSNDTLDMYIDTALKNGITEITFTEHMPLPMEDPSPRKNSAL
CCCCCCCCCCEECCCCCCCCCCCHHHEEHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCC
PMERLEEYIKGITELKEKVKDKIKVNLGLEVDYVEGYEEETKAILNKYGKYLDDAILSVH
CHHHHHHHHHHHHHHHHHHHHHEEEECCEEEEHHCCCHHHHHHHHHHHHHHHHHHHHEEE
IVKFQGEYYQIGNGSDMIGELVEKIGGMDKLYDLYYETMLKSIKCDLGAFKPKRIGHPTL
EEEECCCEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
VRKYKADFPNEKYNIKLLESILKEMKKGNYEIDLNTSGLRREKCGEVHPQGIFLDLCLKY
HHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHCCCCCCCCEEEEEHHHC
NIPMVLGSDSHSSKYVGVEFEKVANMIFPDSEAI
CCCEEECCCCCCCCEECEEHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]