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The map label for this gene is cloSI [H]

Identifier: 18309828

GI number: 18309828

Start: 1032778

End: 1034352

Strand: Direct

Name: cloSI [H]

Synonym: CPE0846

Alternate gene names: 18309828

Gene position: 1032778-1034352 (Clockwise)

Preceding gene: 18309825

Following gene: 18309829

Centisome position: 34.07

GC content: 29.9

Gene sequence:

>1575_bases
ATGTATATGTTTAAGAAAAAGTTATCATTATTGATGGCTACTATTACCATTGGTAGCGTTCTATTAGGAGGAGTTTCAAC
AGTAAGTGCTGCTCCAAGACAAAAGCATAAAACTGTATCAGAGAAAATTAAAGAGGCCGAAAAGACTGAAGGTGATAAAA
AACTAACGGTTATGGTATATGCTGATTGTGATAATAACCTAGAAGAGTACATACTTAATGATATTGAAGAAATGAAAGAG
GGTTATAAAAATAATCCTAATCTAAATATTATAGTATTAGTTGATAGAATTCCTGGTTATTCTAATGATTCAAAAGTGCT
AGGTTCTAATTTTGAAGACACAAGACTTTATAAAATAGGTGAAAATTCTGCTGAAAGAATTAGTGGGAAAAGTGAATTTC
CAGAGATAACTACTACAAGTAATTATGAAGCTAACATGGGAGATGCTAATACTTTAAAAAAATTCATTAAATTCTGTAAA
AAGAACTATGAAGCTGATAAGTATATGTTAATCATGTCTAACCATGGTGGTGGGGCTAAGGATGATAAAGATAGAGCTAG
TACTGTAAATAAGGCAATATGCTGGGATGATAGTAACAACAAAGATTGTCTTTATACTGGTGAAATTTCAGATGTTTTAA
CTAAGGATGAATCTGTTGATGTTTTAGTATTTGATGCTTGTTTAATGGGAAATTCAGAGGTAGCTTATCAATATAGACCT
AATAATGGAAGTTTTGAAGCTAAAACACTTGTAGCATCAGCACCAGTTGTTTGGGGTTTTGGATATCCTTATGACAAAAT
ATTTTCTCGTTTAAGATCTACTAAAGGTGATAATGGAGAAGTTGATTCTACTTTAGGAGGAAAAGAAAAAATATTTGATC
CATCTACGGTTACAAATAATGAACTTGGTGCCTTATTTGTAGAAGAACAACGTGATTCTGTAAATAGCTGTCGAGTAACA
GATCAACAACTAAGTTGCTACGATCTTTCAAAAATTGAAAAAGTTAAAAAATCAGTTGATGCTTTAGCTAGAAATTTAAG
CAAAAATAATAAAAAAGATGCTATTGAAAAATTAAGAGGTACAGGAAAAAATGCACCAACTATGCACTATTTTAAGAATT
ATGATGAATATGAATGGATTGAGTATCCATACTTTGATTTATATGATTTATGTGAAAAAATTAGCTTAAGTGATGAATTT
AATGAAACTACTAAAAAATTATCAAAGAATGTTATGAAAAATGTTGACCAATTAATTTTATATTCATTTGCAGGTAAGGA
CTTTAAAGGCTTCAAAGAAGGAAAAAATGGTATAAGTATTTTCCTTCCTGATGGTAATAGAAATTATTATGATCAATATT
CTGGACAAGCAATACCACATTGGGCTATTCAAAGATGGTACAATCCTCTAGACACTAATGCTTATAGATTAAGAAGTGGT
TATGGAAAACTAGCATGGTGTAAAGATGGATTAGATCCAAAAATAAATAAAGTTGGTAACTGGTTTGAACTTTTAGATTC
TTGGTTCGATAAAGATAATACTTCACTTGGTGGATATAATAGATATAGATATTAA

Upstream 100 bases:

>100_bases
TTTGACCAGTTATGCAAATTGTATTGAAAATTTCATATATTAAATTAATATTAAATTAGTATTAACTTAATGTTAACTTA
ATGTTAATTTTCAGAGGGGG

Downstream 100 bases:

>100_bases
AAGATGATTTCTTAAGATTATATAAAAGAAATTAAGTTAAGAAATAACTCTACTTATAAGGTTTAAGTAGAGTTATTTAT
TTTTGTGTAATTTTTATAAT

Product: alpha-clostripain

Products: NA

Alternate protein names: Clostridiopeptidase B [H]

Number of amino acids: Translated: 524; Mature: 524

Protein sequence:

>524_residues
MYMFKKKLSLLMATITIGSVLLGGVSTVSAAPRQKHKTVSEKIKEAEKTEGDKKLTVMVYADCDNNLEEYILNDIEEMKE
GYKNNPNLNIIVLVDRIPGYSNDSKVLGSNFEDTRLYKIGENSAERISGKSEFPEITTTSNYEANMGDANTLKKFIKFCK
KNYEADKYMLIMSNHGGGAKDDKDRASTVNKAICWDDSNNKDCLYTGEISDVLTKDESVDVLVFDACLMGNSEVAYQYRP
NNGSFEAKTLVASAPVVWGFGYPYDKIFSRLRSTKGDNGEVDSTLGGKEKIFDPSTVTNNELGALFVEEQRDSVNSCRVT
DQQLSCYDLSKIEKVKKSVDALARNLSKNNKKDAIEKLRGTGKNAPTMHYFKNYDEYEWIEYPYFDLYDLCEKISLSDEF
NETTKKLSKNVMKNVDQLILYSFAGKDFKGFKEGKNGISIFLPDGNRNYYDQYSGQAIPHWAIQRWYNPLDTNAYRLRSG
YGKLAWCKDGLDPKINKVGNWFELLDSWFDKDNTSLGGYNRYRY

Sequences:

>Translated_524_residues
MYMFKKKLSLLMATITIGSVLLGGVSTVSAAPRQKHKTVSEKIKEAEKTEGDKKLTVMVYADCDNNLEEYILNDIEEMKE
GYKNNPNLNIIVLVDRIPGYSNDSKVLGSNFEDTRLYKIGENSAERISGKSEFPEITTTSNYEANMGDANTLKKFIKFCK
KNYEADKYMLIMSNHGGGAKDDKDRASTVNKAICWDDSNNKDCLYTGEISDVLTKDESVDVLVFDACLMGNSEVAYQYRP
NNGSFEAKTLVASAPVVWGFGYPYDKIFSRLRSTKGDNGEVDSTLGGKEKIFDPSTVTNNELGALFVEEQRDSVNSCRVT
DQQLSCYDLSKIEKVKKSVDALARNLSKNNKKDAIEKLRGTGKNAPTMHYFKNYDEYEWIEYPYFDLYDLCEKISLSDEF
NETTKKLSKNVMKNVDQLILYSFAGKDFKGFKEGKNGISIFLPDGNRNYYDQYSGQAIPHWAIQRWYNPLDTNAYRLRSG
YGKLAWCKDGLDPKINKVGNWFELLDSWFDKDNTSLGGYNRYRY
>Mature_524_residues
MYMFKKKLSLLMATITIGSVLLGGVSTVSAAPRQKHKTVSEKIKEAEKTEGDKKLTVMVYADCDNNLEEYILNDIEEMKE
GYKNNPNLNIIVLVDRIPGYSNDSKVLGSNFEDTRLYKIGENSAERISGKSEFPEITTTSNYEANMGDANTLKKFIKFCK
KNYEADKYMLIMSNHGGGAKDDKDRASTVNKAICWDDSNNKDCLYTGEISDVLTKDESVDVLVFDACLMGNSEVAYQYRP
NNGSFEAKTLVASAPVVWGFGYPYDKIFSRLRSTKGDNGEVDSTLGGKEKIFDPSTVTNNELGALFVEEQRDSVNSCRVT
DQQLSCYDLSKIEKVKKSVDALARNLSKNNKKDAIEKLRGTGKNAPTMHYFKNYDEYEWIEYPYFDLYDLCEKISLSDEF
NETTKKLSKNVMKNVDQLILYSFAGKDFKGFKEGKNGISIFLPDGNRNYYDQYSGQAIPHWAIQRWYNPLDTNAYRLRSG
YGKLAWCKDGLDPKINKVGNWFELLDSWFDKDNTSLGGYNRYRY

Specific function: Cysteine endopeptidase with strict specificity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C11 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014173
- InterPro:   IPR005077 [H]

Pfam domain/function: PF03415 Peptidase_C11 [H]

EC number: =3.4.22.8 [H]

Molecular weight: Translated: 59587; Mature: 59587

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYMFKKKLSLLMATITIGSVLLGGVSTVSAAPRQKHKTVSEKIKEAEKTEGDKKLTVMVY
CCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEE
ADCDNNLEEYILNDIEEMKEGYKNNPNLNIIVLVDRIPGYSNDSKVLGSNFEDTRLYKIG
ECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEC
ENSAERISGKSEFPEITTTSNYEANMGDANTLKKFIKFCKKNYEADKYMLIMSNHGGGAK
CCHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCC
DDKDRASTVNKAICWDDSNNKDCLYTGEISDVLTKDESVDVLVFDACLMGNSEVAYQYRP
CCHHHHHHHCCEEEECCCCCCCEEEECCHHHHHCCCCCCCEEEEEHHHCCCCCEEEEEEC
NNGSFEAKTLVASAPVVWGFGYPYDKIFSRLRSTKGDNGEVDSTLGGKEKIFDPSTVTNN
CCCCCCHHEEEECCCEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCCCC
ELGALFVEEQRDSVNSCRVTDQQLSCYDLSKIEKVKKSVDALARNLSKNNKKDAIEKLRG
CCCEEEEECCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHC
TGKNAPTMHYFKNYDEYEWIEYPYFDLYDLCEKISLSDEFNETTKKLSKNVMKNVDQLIL
CCCCCCCCHHHCCCCCCCEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
YSFAGKDFKGFKEGKNGISIFLPDGNRNYYDQYSGQAIPHWAIQRWYNPLDTNAYRLRSG
HHHCCCCCCHHHCCCCCEEEEEECCCCCCCHHCCCCCCHHHHHHHHCCCCCCCCEEHHCC
YGKLAWCKDGLDPKINKVGNWFELLDSWFDKDNTSLGGYNRYRY
CCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MYMFKKKLSLLMATITIGSVLLGGVSTVSAAPRQKHKTVSEKIKEAEKTEGDKKLTVMVY
CCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEE
ADCDNNLEEYILNDIEEMKEGYKNNPNLNIIVLVDRIPGYSNDSKVLGSNFEDTRLYKIG
ECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEC
ENSAERISGKSEFPEITTTSNYEANMGDANTLKKFIKFCKKNYEADKYMLIMSNHGGGAK
CCHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCC
DDKDRASTVNKAICWDDSNNKDCLYTGEISDVLTKDESVDVLVFDACLMGNSEVAYQYRP
CCHHHHHHHCCEEEECCCCCCCEEEECCHHHHHCCCCCCCEEEEEHHHCCCCCEEEEEEC
NNGSFEAKTLVASAPVVWGFGYPYDKIFSRLRSTKGDNGEVDSTLGGKEKIFDPSTVTNN
CCCCCCHHEEEECCCEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCCCC
ELGALFVEEQRDSVNSCRVTDQQLSCYDLSKIEKVKKSVDALARNLSKNNKKDAIEKLRG
CCCEEEEECCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHC
TGKNAPTMHYFKNYDEYEWIEYPYFDLYDLCEKISLSDEFNETTKKLSKNVMKNVDQLIL
CCCCCCCCHHHCCCCCCCEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
YSFAGKDFKGFKEGKNGISIFLPDGNRNYYDQYSGQAIPHWAIQRWYNPLDTNAYRLRSG
HHHCCCCCCHHHCCCCCEEEEEECCCCCCCHHCCCCCCHHHHHHHHCCCCCCCCEEHHCC
YGKLAWCKDGLDPKINKVGNWFELLDSWFDKDNTSLGGYNRYRY
CCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8341259; 6391922; 6337850 [H]