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The map label for this gene is phoP [H]

Identifier: 18309624

GI number: 18309624

Start: 804031

End: 804726

Strand: Direct

Name: phoP [H]

Synonym: CPE0642

Alternate gene names: 18309624

Gene position: 804031-804726 (Clockwise)

Preceding gene: 18309623

Following gene: 18309630

Centisome position: 26.52

GC content: 27.73

Gene sequence:

>696_bases
ATGACAAATAAAAAAGTCCTAATAGTAGATGATGAGGAACATATTAGAGAACTTATAAAATTTAATTTAAAAAAAGAGGG
ATATGATACAGAGGTTGCTGTTAATGGAACTGAAGCTCTAAAGGTTATAAGAGAAATTAAGTTTGATTTAATACTTTTAG
ATTTAATGCTTCCAGAAATAGATGGCTTAGAAGTATGTAAAGAAATTAGAAGAAATGAAGAAACTTCAGATATTCCAGTA
ATGATGATTACAGCAAAGGGGGAAGAGTTTGATAAAGTATTAGGCTTAGAACTTGGAGCAGATGATTATATAACAAAGCC
ATTTTCAATAAGAGAACTTATGGCTAGAGTAAAAGCTTTACTCAGAAGAAGTAATGTTAAAAAAGAAGAAAATATAATTA
AATTTGGTGATGTAGTAGTTAATTTTAAAACAAGAGAAGTAACAAAAGGAACTCAAAATGTAGAATTAACATTAAAAGAG
TTTGAATTATTAAAGCTTCTTATAAAGAATAAGGGCAATATATTAACTAGAGAACTTTTGCTTGATAAAATTTGGGGATA
TGAATACATAGGTGAAACAAGAACAGTAGATGTTCATATTAGACATTTACGTAAAAAGATTGAAAGCGATGATAAAAATC
CTCAATATATTCAAACTATAAGAGGCGTTGGGTATAAGTTTACAAGTAATGAGTAA

Upstream 100 bases:

>100_bases
TAATTTAAAGATATATCTATAAGTGGTATATCTTTTTTTGTTTTCAATATTGTGATAAGCTATAAAATAGGGTAGTGTTT
TGGGTAAAGGAGGGACAAGA

Downstream 100 bases:

>100_bases
TTAAAATGTAAAGGATAAACTTATAATTACTTATTAAAGTAGTATATTAAAAAATAAATTGCATATATGAAGAGCAACTT
ATAGGTGTAGTAAATTTAGA

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MTNKKVLIVDDEEHIRELIKFNLKKEGYDTEVAVNGTEALKVIREIKFDLILLDLMLPEIDGLEVCKEIRRNEETSDIPV
MMITAKGEEFDKVLGLELGADDYITKPFSIRELMARVKALLRRSNVKKEENIIKFGDVVVNFKTREVTKGTQNVELTLKE
FELLKLLIKNKGNILTRELLLDKIWGYEYIGETRTVDVHIRHLRKKIESDDKNPQYIQTIRGVGYKFTSNE

Sequences:

>Translated_231_residues
MTNKKVLIVDDEEHIRELIKFNLKKEGYDTEVAVNGTEALKVIREIKFDLILLDLMLPEIDGLEVCKEIRRNEETSDIPV
MMITAKGEEFDKVLGLELGADDYITKPFSIRELMARVKALLRRSNVKKEENIIKFGDVVVNFKTREVTKGTQNVELTLKE
FELLKLLIKNKGNILTRELLLDKIWGYEYIGETRTVDVHIRHLRKKIESDDKNPQYIQTIRGVGYKFTSNE
>Mature_230_residues
TNKKVLIVDDEEHIRELIKFNLKKEGYDTEVAVNGTEALKVIREIKFDLILLDLMLPEIDGLEVCKEIRRNEETSDIPVM
MITAKGEEFDKVLGLELGADDYITKPFSIRELMARVKALLRRSNVKKEENIIKFGDVVVNFKTREVTKGTQNVELTLKEF
ELLKLLIKNKGNILTRELLLDKIWGYEYIGETRTVDVHIRHLRKKIESDDKNPQYIQTIRGVGYKFTSNE

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=234, Percent_Identity=39.7435897435897, Blast_Score=191, Evalue=4e-50,
Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=42.0353982300885, Blast_Score=187, Evalue=5e-49,
Organism=Escherichia coli, GI1788394, Length=229, Percent_Identity=40.174672489083, Blast_Score=174, Evalue=4e-45,
Organism=Escherichia coli, GI1786911, Length=228, Percent_Identity=39.0350877192982, Blast_Score=166, Evalue=8e-43,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=37.5565610859729, Blast_Score=164, Evalue=4e-42,
Organism=Escherichia coli, GI1790860, Length=230, Percent_Identity=37.8260869565217, Blast_Score=157, Evalue=5e-40,
Organism=Escherichia coli, GI87082012, Length=226, Percent_Identity=35.8407079646018, Blast_Score=150, Evalue=9e-38,
Organism=Escherichia coli, GI2367329, Length=232, Percent_Identity=37.0689655172414, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1789402, Length=221, Percent_Identity=34.841628959276, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1790552, Length=227, Percent_Identity=36.1233480176211, Blast_Score=144, Evalue=4e-36,
Organism=Escherichia coli, GI1790863, Length=238, Percent_Identity=36.5546218487395, Blast_Score=143, Evalue=9e-36,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=34.375, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1787229, Length=234, Percent_Identity=32.0512820512821, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI145693140, Length=238, Percent_Identity=30.672268907563, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1788550, Length=162, Percent_Identity=32.0987654320988, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1788191, Length=110, Percent_Identity=32.7272727272727, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1790437, Length=140, Percent_Identity=33.5714285714286, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787487, Length=147, Percent_Identity=29.9319727891156, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790299, Length=118, Percent_Identity=32.2033898305085, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI48994928, Length=131, Percent_Identity=32.0610687022901, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788905, Length=132, Percent_Identity=31.0606060606061, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26855; Mature: 26723

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNKKVLIVDDEEHIRELIKFNLKKEGYDTEVAVNGTEALKVIREIKFDLILLDLMLPEI
CCCCEEEEECCHHHHHHHHHHCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHCCCC
DGLEVCKEIRRNEETSDIPVMMITAKGEEFDKVLGLELGADDYITKPFSIRELMARVKAL
CHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHCCEECCCCCCCCCHHHHHHHHHHHHH
LRRSNVKKEENIIKFGDVVVNFKTREVTKGTQNVELTLKEFELLKLLIKNKGNILTRELL
HHHHCCCHHHCEEEECCEEEEEEHHHHHCCCCCEEEEHHHHHHHHHHHHCCCCCHHHHHH
LDKIWGYEYIGETRTVDVHIRHLRKKIESDDKNPQYIQTIRGVGYKFTSNE
HHHHCCHHHCCCCEEEHHHHHHHHHHHHCCCCCHHHHHHHHHCCEEECCCC
>Mature Secondary Structure 
TNKKVLIVDDEEHIRELIKFNLKKEGYDTEVAVNGTEALKVIREIKFDLILLDLMLPEI
CCCEEEEECCHHHHHHHHHHCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHCCCC
DGLEVCKEIRRNEETSDIPVMMITAKGEEFDKVLGLELGADDYITKPFSIRELMARVKAL
CHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHCCEECCCCCCCCCHHHHHHHHHHHHH
LRRSNVKKEENIIKFGDVVVNFKTREVTKGTQNVELTLKEFELLKLLIKNKGNILTRELL
HHHHCCCHHHCEEEECCEEEEEEHHHHHCCCCCEEEEHHHHHHHHHHHHCCCCCHHHHHH
LDKIWGYEYIGETRTVDVHIRHLRKKIESDDKNPQYIQTIRGVGYKFTSNE
HHHHCCHHHCCCCEEEHHHHHHHHHHHHCCCCCHHHHHHHHHCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]