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The map label for this gene is arsC [H]

Identifier: 182680299

GI number: 182680299

Start: 3860960

End: 3861310

Strand: Reverse

Name: arsC [H]

Synonym: Bind_3399

Alternate gene names: 182680299

Gene position: 3861310-3860960 (Counterclockwise)

Preceding gene: 182680300

Following gene: 182680297

Centisome position: 92.59

GC content: 57.55

Gene sequence:

>351_bases
ATGGATTATGTGATCTTTCATAATCCGTCTTGCGGAACGTCGCGCAAGGTCCTGGCGGCCTTGCGCGAGGCCGGAATAGA
GTTGGAAATCCGGCTCTATTTGAAAAGCCCGCCGTCTCCAGCCGAACTTGCTGATCTGCTTGCCCGTATGGACATGACGC
CGCGCGCCCTGCTGCGCCGGAAAGAAAAAGTCTATGCCGAACTGGGGCTCGACGACAAAAGCCTCAGTGATGCCACGTTG
ATTGCTGCGATGAGCGCGCATCCGATCCTGATTGAACGGCCGATCGTCGTAACGCCGAAACAGGCCGTCCTTTGCCGTCC
GCCGGAAAAAGTGGAGGCCTTGCTTCCCTGA

Upstream 100 bases:

>100_bases
TCAGCTATGGCAAGGAACGCCCCGTCGCGACCTGTGACGATATTTCCTGCTGGTCGCAGAACCGCCGCGCGGTCACGGTG
CTCGGGGCCGGCCAATCCTG

Downstream 100 bases:

>100_bases
CGGGGTAACCATCCGCACAATTAGGCCGCCCAATCAGGCGGCGAGATCGGCGATCACGGCGTCGAGCACGGGAAAACCTT
CCGCGCTCACGCGCACACGG

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenical pump modifier [H]

Number of amino acids: Translated: 116; Mature: 116

Protein sequence:

>116_residues
MDYVIFHNPSCGTSRKVLAALREAGIELEIRLYLKSPPSPAELADLLARMDMTPRALLRRKEKVYAELGLDDKSLSDATL
IAAMSAHPILIERPIVVTPKQAVLCRPPEKVEALLP

Sequences:

>Translated_116_residues
MDYVIFHNPSCGTSRKVLAALREAGIELEIRLYLKSPPSPAELADLLARMDMTPRALLRRKEKVYAELGLDDKSLSDATL
IAAMSAHPILIERPIVVTPKQAVLCRPPEKVEALLP
>Mature_116_residues
MDYVIFHNPSCGTSRKVLAALREAGIELEIRLYLKSPPSPAELADLLARMDMTPRALLRRKEKVYAELGLDDKSLSDATL
IAAMSAHPILIERPIVVTPKQAVLCRPPEKVEALLP

Specific function: Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance [H]

COG id: COG1393

COG function: function code P; Arsenate reductase and related proteins, glutaredoxin family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsC family [H]

Homologues:

Organism=Escherichia coli, GI1789918, Length=115, Percent_Identity=49.5652173913044, Blast_Score=110, Evalue=3e-26,
Organism=Escherichia coli, GI1788841, Length=108, Percent_Identity=50, Blast_Score=102, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006659
- InterPro:   IPR006660
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF03960 ArsC [H]

EC number: =1.20.4.1 [H]

Molecular weight: Translated: 12829; Mature: 12829

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYVIFHNPSCGTSRKVLAALREAGIELEIRLYLKSPPSPAELADLLARMDMTPRALLRR
CCEEEEECCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHH
KEKVYAELGLDDKSLSDATLIAAMSAHPILIERPIVVTPKQAVLCRPPEKVEALLP
HHHHHHHCCCCCCCCCCHHEEEECCCCCEEEECCEEECCCCCEEECCHHHHHCCCC
>Mature Secondary Structure
MDYVIFHNPSCGTSRKVLAALREAGIELEIRLYLKSPPSPAELADLLARMDMTPRALLRR
CCEEEEECCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHH
KEKVYAELGLDDKSLSDATLIAAMSAHPILIERPIVVTPKQAVLCRPPEKVEALLP
HHHHHHHCCCCCCCCCCHHEEEECCCCCEEEECCEEECCCCCEEECCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9006011 [H]