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The map label for this gene is mmoX [H]

Identifier: 182680297

GI number: 182680297

Start: 3857579

End: 3859237

Strand: Reverse

Name: mmoX [H]

Synonym: Bind_3397

Alternate gene names: 182680297

Gene position: 3859237-3857579 (Counterclockwise)

Preceding gene: 182680299

Following gene: 182680296

Centisome position: 92.54

GC content: 55.09

Gene sequence:

>1659_bases
ATGGCTGTATCCCTGACAAGCATAACCCAGCAGAAAGGTATGCCGATCGCCGAAGCGACACGGCGCATTTCTGATCTCGG
ATGGACGCCTTCCTATGTTCAGGAAGCGATGACCTTTCCGACCGATTACAAAATTTCCAAACAGCCTAAGGACCCGATGA
AACAGGTCCTGCGCTCCTATTTCCCGATGCAGGAGGAAAAGGACAATCGCGTCTATGGCGCGCTCGACGCGGCTCTGCGC
GGCGATATGTTCCGCAATGTGGAGCAGCGTTGGGTCGAATGGATGAAGCTGTTTCTGGCCATCATCCCCTTCCCGGAAAT
TTCTGCCGCGCGGTCCATGGCCATGCTTGGCCGTCTTGCGCCGGGCGATGATCTGCGTACCGGCTTCACCATGCAAATGG
TCGACGAATTCCGTCATTCCACGATTCAGATGAATCTGAAGAAGTGGTACATGGAAAACTACATCGATCCGGCTGGCTTC
GACATTACCGAAAAGGCTTTCGGTAAATGCTATGCGACCACGATTGGCCGCCAGTTCGGTGAGGCCTTCATCACGGGCGA
TGCGATCACCGCCGCGAATGTGTATCTGCAAGTGGTGGCTGAGACGGCCTTCACGAACACTTTGTTCGTGGCCATGCCGT
CCGAAGCCGCGCGCAATGGTGACTATGCCCTGCCGACCGTCTTCCTTTCCGTGCAATCGGATGAATCGCGGCACATCGGC
AACGGCCATTCGCTTTTGATGTCGATCCTCAACAATCCTGATAATCATCTGCTGCTCGAGCGCGATATCCGTTATGCCTT
CTGGCAGAATCACGCGATTGTCGATGCGGCGGTTGGAACGATCATCGAATATGGGACGAAGAACCGCGACAAGAAGAAGG
AATCCTACGCCGAGCTCTGGCATCGCTGGATCTATGAGGATTACTATCGCACCTACATGCTCCCGCTCGAAAAATACGGG
ATCAAGATCCATCATGATGATGTGCATCAGGCCTGGGAAGACATCACCAAGAATGGTTATGTCCATAAGGTCGCGCAATT
CTTCTCGGCCGGCTGGTGGGCCAATTTCTGGCGCATCGATCCGCTCGACGAGCGTGACTTCGACTGGTTCGAATATAAAT
ATCCGGGCTGGTACAATGAATATGGCGCGTGGTGGGAGAACTATCGCAAATTGTCGAAGCCCGGCAGCATTCCGATCACC
TTTGCTGATACCGGATATGTCTATCCGCATCGTTGTTGGTCCAATCTCGTGCCTTGCGTCATCCGTGATCAGATCAAGGT
CGATGAAGTCGATGGCCAGCTCTACACTTATGGCAGCGAAGTCGACCGCTGGACGCATAAGGAAGCCTTCTCGGGCGAAT
ACAAGGGCCGTTCGACGCCGGCCATGGGTCGCTTCAGCGGCCGCCGTCAATGGGAAGAACTCTATGATGGCTGGGATGTC
GCCGATGCGATCAAGGACATGGGCTTTGTCCGCGCCGATGGCAAAACCCTGATCGCGCAGCCGCATCTTTCCCTTGACGA
AAAGGATCTGTGGACGCTCGATCATGTGCGCGGCAACACGATCAAGGCGCCGCTCAAAACCTTGCGCGAGCTTTCGCCCG
CCGATCGCGAGAAACATCTCGCCGAATATCGCAAGGGTGTCACCATTCGCCGCGTCTGA

Upstream 100 bases:

>100_bases
GGGAAGGTGGGGAAGGAGAGGGTGCAGGGCCACACAAGTCGCTCCCGACTGAAGACCGATCACGCATTCATTGCGCGTGA
CCTATGGGAGGAACTGGAGA

Downstream 100 bases:

>100_bases
TCGTCGGCTCGAGTGATCGCTGGCCAGAGTGACGGCCGCGACGAGGAGGCTGGGACATCCAAACCCTCCGATGTTCCAGC
CTCCAACCTCATTGATGATC

Product: methane monooxygenase

Products: NA

Alternate protein names: Methane hydroxylase [H]

Number of amino acids: Translated: 552; Mature: 551

Protein sequence:

>552_residues
MAVSLTSITQQKGMPIAEATRRISDLGWTPSYVQEAMTFPTDYKISKQPKDPMKQVLRSYFPMQEEKDNRVYGALDAALR
GDMFRNVEQRWVEWMKLFLAIIPFPEISAARSMAMLGRLAPGDDLRTGFTMQMVDEFRHSTIQMNLKKWYMENYIDPAGF
DITEKAFGKCYATTIGRQFGEAFITGDAITAANVYLQVVAETAFTNTLFVAMPSEAARNGDYALPTVFLSVQSDESRHIG
NGHSLLMSILNNPDNHLLLERDIRYAFWQNHAIVDAAVGTIIEYGTKNRDKKKESYAELWHRWIYEDYYRTYMLPLEKYG
IKIHHDDVHQAWEDITKNGYVHKVAQFFSAGWWANFWRIDPLDERDFDWFEYKYPGWYNEYGAWWENYRKLSKPGSIPIT
FADTGYVYPHRCWSNLVPCVIRDQIKVDEVDGQLYTYGSEVDRWTHKEAFSGEYKGRSTPAMGRFSGRRQWEELYDGWDV
ADAIKDMGFVRADGKTLIAQPHLSLDEKDLWTLDHVRGNTIKAPLKTLRELSPADREKHLAEYRKGVTIRRV

Sequences:

>Translated_552_residues
MAVSLTSITQQKGMPIAEATRRISDLGWTPSYVQEAMTFPTDYKISKQPKDPMKQVLRSYFPMQEEKDNRVYGALDAALR
GDMFRNVEQRWVEWMKLFLAIIPFPEISAARSMAMLGRLAPGDDLRTGFTMQMVDEFRHSTIQMNLKKWYMENYIDPAGF
DITEKAFGKCYATTIGRQFGEAFITGDAITAANVYLQVVAETAFTNTLFVAMPSEAARNGDYALPTVFLSVQSDESRHIG
NGHSLLMSILNNPDNHLLLERDIRYAFWQNHAIVDAAVGTIIEYGTKNRDKKKESYAELWHRWIYEDYYRTYMLPLEKYG
IKIHHDDVHQAWEDITKNGYVHKVAQFFSAGWWANFWRIDPLDERDFDWFEYKYPGWYNEYGAWWENYRKLSKPGSIPIT
FADTGYVYPHRCWSNLVPCVIRDQIKVDEVDGQLYTYGSEVDRWTHKEAFSGEYKGRSTPAMGRFSGRRQWEELYDGWDV
ADAIKDMGFVRADGKTLIAQPHLSLDEKDLWTLDHVRGNTIKAPLKTLRELSPADREKHLAEYRKGVTIRRV
>Mature_551_residues
AVSLTSITQQKGMPIAEATRRISDLGWTPSYVQEAMTFPTDYKISKQPKDPMKQVLRSYFPMQEEKDNRVYGALDAALRG
DMFRNVEQRWVEWMKLFLAIIPFPEISAARSMAMLGRLAPGDDLRTGFTMQMVDEFRHSTIQMNLKKWYMENYIDPAGFD
ITEKAFGKCYATTIGRQFGEAFITGDAITAANVYLQVVAETAFTNTLFVAMPSEAARNGDYALPTVFLSVQSDESRHIGN
GHSLLMSILNNPDNHLLLERDIRYAFWQNHAIVDAAVGTIIEYGTKNRDKKKESYAELWHRWIYEDYYRTYMLPLEKYGI
KIHHDDVHQAWEDITKNGYVHKVAQFFSAGWWANFWRIDPLDERDFDWFEYKYPGWYNEYGAWWENYRKLSKPGSIPITF
ADTGYVYPHRCWSNLVPCVIRDQIKVDEVDGQLYTYGSEVDRWTHKEAFSGEYKGRSTPAMGRFSGRRQWEELYDGWDVA
DAIKDMGFVRADGKTLIAQPHLSLDEKDLWTLDHVRGNTIKAPLKTLRELSPADREKHLAEYRKGVTIRRV

Specific function: Responsible for the initial oxygenation of methane to methanol in methanotrophs. It also catalyzes the monohydroxylation of a variety of unactivated alkenes, alicyclic, aromatic and heterocyclic compounds [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009078
- InterPro:   IPR003430
- InterPro:   IPR012348 [H]

Pfam domain/function: PF02332 Phenol_Hydrox [H]

EC number: =1.14.13.25 [H]

Molecular weight: Translated: 64169; Mature: 64038

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVSLTSITQQKGMPIAEATRRISDLGWTPSYVQEAMTFPTDYKISKQPKDPMKQVLRSY
CEEEECHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
FPMQEEKDNRVYGALDAALRGDMFRNVEQRWVEWMKLFLAIIPFPEISAARSMAMLGRLA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
PGDDLRTGFTMQMVDEFRHSTIQMNLKKWYMENYIDPAGFDITEKAFGKCYATTIGRQFG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
EAFITGDAITAANVYLQVVAETAFTNTLFVAMPSEAARNGDYALPTVFLSVQSDESRHIG
HHEECCCHHHHHHHHHHHHHHHHHCCEEEEEECCHHHCCCCCCCEEEEEEEECCCCCCCC
NGHSLLMSILNNPDNHLLLERDIRYAFWQNHAIVDAAVGTIIEYGTKNRDKKKESYAELW
CHHHHHHHHHCCCCCCEEEECCHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHH
HRWIYEDYYRTYMLPLEKYGIKIHHDDVHQAWEDITKNGYVHKVAQFFSAGWWANFWRID
HHHHHHHHHHHHHCCHHHCCEEEEEHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEECC
PLDERDFDWFEYKYPGWYNEYGAWWENYRKLSKPGSIPITFADTGYVYPHRCWSNLVPCV
CCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHCCCCCH
IRDQIKVDEVDGQLYTYGSEVDRWTHKEAFSGEYKGRSTPAMGRFSGRRQWEELYDGWDV
HHCCCEEEECCCEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCH
ADAIKDMGFVRADGKTLIAQPHLSLDEKDLWTLDHVRGNTIKAPLKTLRELSPADREKHL
HHHHHHCCEEEECCCEEEECCCCCCCCCCCEEHHCCCCCCCHHHHHHHHHCCCCHHHHHH
AEYRKGVTIRRV
HHHHCCCEEECC
>Mature Secondary Structure 
AVSLTSITQQKGMPIAEATRRISDLGWTPSYVQEAMTFPTDYKISKQPKDPMKQVLRSY
EEEECHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
FPMQEEKDNRVYGALDAALRGDMFRNVEQRWVEWMKLFLAIIPFPEISAARSMAMLGRLA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
PGDDLRTGFTMQMVDEFRHSTIQMNLKKWYMENYIDPAGFDITEKAFGKCYATTIGRQFG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
EAFITGDAITAANVYLQVVAETAFTNTLFVAMPSEAARNGDYALPTVFLSVQSDESRHIG
HHEECCCHHHHHHHHHHHHHHHHHCCEEEEEECCHHHCCCCCCCEEEEEEEECCCCCCCC
NGHSLLMSILNNPDNHLLLERDIRYAFWQNHAIVDAAVGTIIEYGTKNRDKKKESYAELW
CHHHHHHHHHCCCCCCEEEECCHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHH
HRWIYEDYYRTYMLPLEKYGIKIHHDDVHQAWEDITKNGYVHKVAQFFSAGWWANFWRID
HHHHHHHHHHHHHCCHHHCCEEEEEHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEECC
PLDERDFDWFEYKYPGWYNEYGAWWENYRKLSKPGSIPITFADTGYVYPHRCWSNLVPCV
CCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHCCCCCH
IRDQIKVDEVDGQLYTYGSEVDRWTHKEAFSGEYKGRSTPAMGRFSGRRQWEELYDGWDV
HHCCCEEEECCCEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCH
ADAIKDMGFVRADGKTLIAQPHLSLDEKDLWTLDHVRGNTIKAPLKTLRELSPADREKHL
HHHHHHCCEEEECCCEEEECCCCCCCCCCCEEHHCCCCCCCHHHHHHHHHCCCCHHHHHH
AEYRKGVTIRRV
HHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2205538; 8255292; 9432288; 9329079; 11456616 [H]