Click here to switch to the map view.

The map label for this gene is xylR [H]

Identifier: 182680197

GI number: 182680197

Start: 3747341

End: 3748627

Strand: Reverse

Name: xylR [H]

Synonym: Bind_3295

Alternate gene names: 182680197

Gene position: 3748627-3747341 (Counterclockwise)

Preceding gene: 182680199

Following gene: 182680196

Centisome position: 89.89

GC content: 58.82

Gene sequence:

>1287_bases
ATGCAGACAGGAGACACAGAACTCATCCGGGCGATCAATCGTTTTCATGTCCTCGATACGATCAGGCGTTTTGAACCCGT
CTCTCGGGCTGCGATCGGCAAGCGCACACATTTGAGCCGTGTGACGGTGTCTTCACTGATTGCGACGCTGCTGCAGGAAG
GCCTTATCCACGAGGAAAGCGACGAAACGACAAATTCCGGAACGCGGGGACGACCGACGAACCTGCTCGGCTTGAACCCG
AACGCGGCCTATGTCGTTGGCGCGAAATTGTCGATGCATCAGGTTTTTCTGATCGTCACTAATTTGCGGGCCGATCCGCT
GGCGCGCCTCAGTCTTCCTCTTCATCCTCATCAGCTTGTGCCTGATGCTATCGTCGCTCTCCTCGATGAAGGCGTGCGTT
CGGTCGTTGCTTTGGCCGGACTGAAGCTCGGCCAGATCGCAGGGCTTGGCATCGGCCTGCCAGGTTTTATCGATTCCAAG
GCGGGAATTTCCCACTGGAGTCCGATTCTTGCCCCCGAGCCCAAGCCGGTTGCCTTGGCCGATATGGTGCGTCGCCGTCT
TGGCCTCGCCGTCACAATCGAAAACGATGCCAACCTCCTGACACTCGCCGAGCGCTGGTTCGGCGAGTGTCAGGAGAATG
ATAATTTCGTCGTCGTCATGATGGAAGCGGGCATCGGCATGGGCCTGTTTCTTGATGGCGAGCTTTATCGCGGTCAGCAC
GGAATGGGGACGGAATTCGGTCATTCCAAAATCGACCGTCACGGACCGCGTTGCCGTTGCGGACAATATGGCTGCATCGA
GGCTTTTACTGCTGATTATGCGATCCTGCGGGAAGCGGAAAAAATCATCAGAACGCCAGCAGCCCATGAGGGAGCTGATG
ATACGGCTGAGGCTGAGACGCGCGTCGCGACCGTCGTACGGCTGGCGCGTGAGGGCAATGTCGCGCTGCGCCAGATCTTC
GCGACGGCCGGGGAGATTCTAGGCCTCGGCATCGCCAATCTGATCAATATTATCGACCCGGCCAAGATTGTCATTTCCGG
GTCCGGCACACGCGCCGTGGATTTGATTGAGCCGGCGCTCCGCGCGGCGGTCGCGGCGAATACGCTTGCTGTTTTGCAAA
ATCGCTGCGAAATCATCTTTCATGATCAGGGTGACGAAGTCTGGGCGCGTGGCGCGGCCTCCCTCGTGCTGCAAGCGCTC
TATCGCAAGCCATGGACCCCCGCCAGTGGGGCGGAAATCGCGATCATGCCAGGCACGACCGCACGCCATCAAAAGGGCCG
TCCCTGA

Upstream 100 bases:

>100_bases
TTCCGATTTTGATCATGGGCATGTTTGTAGAATGCGTGGCTTAGGGCTCATGTTTCTTGTCGGAAACGACGGGCGGTAGG
AAAAGGTCGGATCGTAAGCG

Downstream 100 bases:

>100_bases
TCATCATGCCGTGCGAACGGAAGCATACACTATCTTGAGGATTCTTCATGCCGAGAACCATCAACAAAGACACGATGTTA
TGTATGTCCCTTTCGGGGCG

Product: ROK family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MQTGDTELIRAINRFHVLDTIRRFEPVSRAAIGKRTHLSRVTVSSLIATLLQEGLIHEESDETTNSGTRGRPTNLLGLNP
NAAYVVGAKLSMHQVFLIVTNLRADPLARLSLPLHPHQLVPDAIVALLDEGVRSVVALAGLKLGQIAGLGIGLPGFIDSK
AGISHWSPILAPEPKPVALADMVRRRLGLAVTIENDANLLTLAERWFGECQENDNFVVVMMEAGIGMGLFLDGELYRGQH
GMGTEFGHSKIDRHGPRCRCGQYGCIEAFTADYAILREAEKIIRTPAAHEGADDTAEAETRVATVVRLAREGNVALRQIF
ATAGEILGLGIANLINIIDPAKIVISGSGTRAVDLIEPALRAAVAANTLAVLQNRCEIIFHDQGDEVWARGAASLVLQAL
YRKPWTPASGAEIAIMPGTTARHQKGRP

Sequences:

>Translated_428_residues
MQTGDTELIRAINRFHVLDTIRRFEPVSRAAIGKRTHLSRVTVSSLIATLLQEGLIHEESDETTNSGTRGRPTNLLGLNP
NAAYVVGAKLSMHQVFLIVTNLRADPLARLSLPLHPHQLVPDAIVALLDEGVRSVVALAGLKLGQIAGLGIGLPGFIDSK
AGISHWSPILAPEPKPVALADMVRRRLGLAVTIENDANLLTLAERWFGECQENDNFVVVMMEAGIGMGLFLDGELYRGQH
GMGTEFGHSKIDRHGPRCRCGQYGCIEAFTADYAILREAEKIIRTPAAHEGADDTAEAETRVATVVRLAREGNVALRQIF
ATAGEILGLGIANLINIIDPAKIVISGSGTRAVDLIEPALRAAVAANTLAVLQNRCEIIFHDQGDEVWARGAASLVLQAL
YRKPWTPASGAEIAIMPGTTARHQKGRP
>Mature_428_residues
MQTGDTELIRAINRFHVLDTIRRFEPVSRAAIGKRTHLSRVTVSSLIATLLQEGLIHEESDETTNSGTRGRPTNLLGLNP
NAAYVVGAKLSMHQVFLIVTNLRADPLARLSLPLHPHQLVPDAIVALLDEGVRSVVALAGLKLGQIAGLGIGLPGFIDSK
AGISHWSPILAPEPKPVALADMVRRRLGLAVTIENDANLLTLAERWFGECQENDNFVVVMMEAGIGMGLFLDGELYRGQH
GMGTEFGHSKIDRHGPRCRCGQYGCIEAFTADYAILREAEKIIRTPAAHEGADDTAEAETRVATVVRLAREGNVALRQIF
ATAGEILGLGIANLINIIDPAKIVISGSGTRAVDLIEPALRAAVAANTLAVLQNRCEIIFHDQGDEVWARGAASLVLQAL
YRKPWTPASGAEIAIMPGTTARHQKGRP

Specific function: Transcriptional repressor of xylose-utilizing enzymes [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=204, Percent_Identity=33.8235294117647, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI298566325, Length=204, Percent_Identity=33.8235294117647, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI4885285, Length=204, Percent_Identity=33.8235294117647, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI190014632, Length=204, Percent_Identity=33.8235294117647, Blast_Score=102, Evalue=9e-22,
Organism=Homo sapiens, GI298566312, Length=115, Percent_Identity=33.0434782608696, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1786891, Length=399, Percent_Identity=26.0651629072682, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1787878, Length=407, Percent_Identity=25.0614250614251, Blast_Score=131, Evalue=9e-32,
Organism=Escherichia coli, GI87082127, Length=343, Percent_Identity=23.3236151603499, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1787363, Length=236, Percent_Identity=26.6949152542373, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87081733, Length=310, Percent_Identity=25.8064516129032, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 46073; Mature: 46073

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTGDTELIRAINRFHVLDTIRRFEPVSRAAIGKRTHLSRVTVSSLIATLLQEGLIHEES
CCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCC
DETTNSGTRGRPTNLLGLNPNAAYVVGAKLSMHQVFLIVTNLRADPLARLSLPLHPHQLV
CCCCCCCCCCCCCCEEEECCCCEEEEECCCCHHEEEEEEECCCCCCHHHEECCCCCHHHH
PDAIVALLDEGVRSVVALAGLKLGQIAGLGIGLPGFIDSKAGISHWSPILAPEPKPVALA
HHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
DMVRRRLGLAVTIENDANLLTLAERWFGECQENDNFVVVMMEAGIGMGLFLDGELYRGQH
HHHHHHCCEEEEEECCCCEEHHHHHHHHHCCCCCCEEEEEEECCCCEEEEECCCEECCCC
GMGTEFGHSKIDRHGPRCRCGQYGCIEAFTADYAILREAEKIIRTPAAHEGADDTAEAET
CCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
RVATVVRLAREGNVALRQIFATAGEILGLGIANLINIIDPAKIVISGSGTRAVDLIEPAL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHH
RAAVAANTLAVLQNRCEIIFHDQGDEVWARGAASLVLQALYRKPWTPASGAEIAIMPGTT
HHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCC
ARHQKGRP
CCCCCCCC
>Mature Secondary Structure
MQTGDTELIRAINRFHVLDTIRRFEPVSRAAIGKRTHLSRVTVSSLIATLLQEGLIHEES
CCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCC
DETTNSGTRGRPTNLLGLNPNAAYVVGAKLSMHQVFLIVTNLRADPLARLSLPLHPHQLV
CCCCCCCCCCCCCCEEEECCCCEEEEECCCCHHEEEEEEECCCCCCHHHEECCCCCHHHH
PDAIVALLDEGVRSVVALAGLKLGQIAGLGIGLPGFIDSKAGISHWSPILAPEPKPVALA
HHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
DMVRRRLGLAVTIENDANLLTLAERWFGECQENDNFVVVMMEAGIGMGLFLDGELYRGQH
HHHHHHCCEEEEEECCCCEEHHHHHHHHHCCCCCCEEEEEEECCCCEEEEECCCEECCCC
GMGTEFGHSKIDRHGPRCRCGQYGCIEAFTADYAILREAEKIIRTPAAHEGADDTAEAET
CCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
RVATVVRLAREGNVALRQIFATAGEILGLGIANLINIIDPAKIVISGSGTRAVDLIEPAL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHH
RAAVAANTLAVLQNRCEIIFHDQGDEVWARGAASLVLQALYRKPWTPASGAEIAIMPGTT
HHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCC
ARHQKGRP
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2544559 [H]