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The map label for this gene is ttuB [H]

Identifier: 182679983

GI number: 182679983

Start: 3516296

End: 3517669

Strand: Reverse

Name: ttuB [H]

Synonym: Bind_3079

Alternate gene names: 182679983

Gene position: 3517669-3516296 (Counterclockwise)

Preceding gene: 182679984

Following gene: 182679982

Centisome position: 84.35

GC content: 60.92

Gene sequence:

>1374_bases
ATGTCAGAGACAATCGTCAATCATGTTTCAAGATCGTCTTCCCGATCGCAGCTTCGCCCTGCAGCCATGGCGTCCGGTGC
TCATTCCTCGGAAGAACGGCAGATCATCGGGCTCATCAGCCGGAAGTTGCTGCCTTTTCTGGCGGTGATCTACATTGTTG
CTTACGTGGATCGGGCGGTGCTCGGCTTCGCCAAGCTGCATATGAATGCGGATGTGGGCATTGGAGATGCTGCCTACGGC
CTTGGCGCGGGGTTGTTCTTCGTCGGCTACTTCCTGTGCGAAGTCCCGAGCAATCTCGCCTTGGAGCGTTTTGGTCCCCG
GCTTTGGTTCGCCCGTATTCTCGCGACCTGGGGCCTCATCACGATCGCCATGTCGCTCATTTCCGGCCCGCTGTCTTTCT
ATATTTTGCGCTTCCTTCTAGGCGCGGCGGAGGCTGGCCTCTATCCGGGTATCCTCTACGTCCTCACCAAATGGTTCCCG
CTGCGCCACAGGGCGCGGATCATCGGCCTTCTGGTGCTGGCCCAGCCCATTGCGCTGATCGTGACCGGACCCATCGCCGG
GCTGATCCTTTCCACTCCGGGCGCCTTCGGGCTGAGCAACTGGCAGGTCCTGTTCATCGTCTGCGGACTGCCCGCGATGC
TCCTGGCGCTGCCGACATTATGGATCCTGCCCGCGTCGCCGCGTCATGCCCGCTGGCTTACGCCGCACCAATTGTCCTGG
ATCGAAAGGGAGCTCGCCGCGGAGAAAACCACCTTGAAGCTCGAGTCCCACAGCAATCCGCTCCGGGCCATCACCGACAG
GAGGGTTCTGCTTCTTGCCCTTCTGTTCCTGCCGTTCCCGCTCGCCATCTATGGTCTGTCACTGTGGCTGCCGACCATCA
TCAAGCAGTTCGGCGTCAGCGACCTTGCAATTGGCTTCCTGTCGACGGTCCCCTATCTGTTTGCGGTCGCGGGCTTGTGC
ATCATTCCCGCCCATTCCGATGCCCGCGGTGAGCGTCACTGGCACATTGTCGTCGTCGCGGCTCTGGCAGCCGTGACCCT
TGCCGCCAGTGCTTTTGTTGAGACGCCGGCGCTGCAACTGCTCTTCCTGTCTTTGGCGGCCTTCTGCATCTATCCGATCC
AGGCCGTGATCTGGACGCTGCCCGGTGTCTTCCTCACCGGCGCGAGTGCCGCGGTGGGTATCGCCACCATCAACTCCCTC
GCCAATCTTGGCGGCTACATCGGGCCCTATGGCATTGGCCTCTTGAAGGACGCGACAGGCAGCACCGCCGCGGGCCTCTA
TTTTCTCGCGGCCGTGCTGTTGTTCGGCGTGTTCATGGCCTTCGTCGTGCGCGCTTCGCTAGACAAAACACAGGCCCTTA
AATCAAGGAGATAA

Upstream 100 bases:

>100_bases
GTCTTGCAATGGGGCAGGTGAGGGCGGCGACGCTCCCAGGCACATACAACGACAATAAACAAAATCATGGCCAGGACAAT
CACGGCCAAAGGGGAAGGAA

Downstream 100 bases:

>100_bases
GACCTATGGCGATAAAAGGAGAGAGCCTGATCGGGAGCCGCGACGTGTCGACAGTACAGACCTTCCACGCCGTCAATCCC
GCGACCGGCCTCACGATCGA

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 456

Protein sequence:

>457_residues
MSETIVNHVSRSSSRSQLRPAAMASGAHSSEERQIIGLISRKLLPFLAVIYIVAYVDRAVLGFAKLHMNADVGIGDAAYG
LGAGLFFVGYFLCEVPSNLALERFGPRLWFARILATWGLITIAMSLISGPLSFYILRFLLGAAEAGLYPGILYVLTKWFP
LRHRARIIGLLVLAQPIALIVTGPIAGLILSTPGAFGLSNWQVLFIVCGLPAMLLALPTLWILPASPRHARWLTPHQLSW
IERELAAEKTTLKLESHSNPLRAITDRRVLLLALLFLPFPLAIYGLSLWLPTIIKQFGVSDLAIGFLSTVPYLFAVAGLC
IIPAHSDARGERHWHIVVVAALAAVTLAASAFVETPALQLLFLSLAAFCIYPIQAVIWTLPGVFLTGASAAVGIATINSL
ANLGGYIGPYGIGLLKDATGSTAAGLYFLAAVLLFGVFMAFVVRASLDKTQALKSRR

Sequences:

>Translated_457_residues
MSETIVNHVSRSSSRSQLRPAAMASGAHSSEERQIIGLISRKLLPFLAVIYIVAYVDRAVLGFAKLHMNADVGIGDAAYG
LGAGLFFVGYFLCEVPSNLALERFGPRLWFARILATWGLITIAMSLISGPLSFYILRFLLGAAEAGLYPGILYVLTKWFP
LRHRARIIGLLVLAQPIALIVTGPIAGLILSTPGAFGLSNWQVLFIVCGLPAMLLALPTLWILPASPRHARWLTPHQLSW
IERELAAEKTTLKLESHSNPLRAITDRRVLLLALLFLPFPLAIYGLSLWLPTIIKQFGVSDLAIGFLSTVPYLFAVAGLC
IIPAHSDARGERHWHIVVVAALAAVTLAASAFVETPALQLLFLSLAAFCIYPIQAVIWTLPGVFLTGASAAVGIATINSL
ANLGGYIGPYGIGLLKDATGSTAAGLYFLAAVLLFGVFMAFVVRASLDKTQALKSRR
>Mature_456_residues
SETIVNHVSRSSSRSQLRPAAMASGAHSSEERQIIGLISRKLLPFLAVIYIVAYVDRAVLGFAKLHMNADVGIGDAAYGL
GAGLFFVGYFLCEVPSNLALERFGPRLWFARILATWGLITIAMSLISGPLSFYILRFLLGAAEAGLYPGILYVLTKWFPL
RHRARIIGLLVLAQPIALIVTGPIAGLILSTPGAFGLSNWQVLFIVCGLPAMLLALPTLWILPASPRHARWLTPHQLSWI
ERELAAEKTTLKLESHSNPLRAITDRRVLLLALLFLPFPLAIYGLSLWLPTIIKQFGVSDLAIGFLSTVPYLFAVAGLCI
IPAHSDARGERHWHIVVVAALAAVTLAASAFVETPALQLLFLSLAAFCIYPIQAVIWTLPGVFLTGASAAVGIATINSLA
NLGGYIGPYGIGLLKDATGSTAAGLYFLAAVLLFGVFMAFVVRASLDKTQALKSRR

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=416, Percent_Identity=34.6153846153846, Blast_Score=231, Evalue=9e-62,
Organism=Escherichia coli, GI87082320, Length=405, Percent_Identity=24.9382716049383, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI2367379, Length=414, Percent_Identity=23.6714975845411, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1789515, Length=453, Percent_Identity=23.1788079470199, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789152, Length=420, Percent_Identity=21.9047619047619, Blast_Score=76, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6319876, Length=365, Percent_Identity=21.9178082191781, Blast_Score=67, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6321698, Length=289, Percent_Identity=21.7993079584775, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322025, Length=205, Percent_Identity=22.9268292682927, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49219; Mature: 49088

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETIVNHVSRSSSRSQLRPAAMASGAHSSEERQIIGLISRKLLPFLAVIYIVAYVDRAV
CCCHHHHHHHCCCCHHHCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGFAKLHMNADVGIGDAAYGLGAGLFFVGYFLCEVPSNLALERFGPRLWFARILATWGLI
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCHHHHHHHHHHHHHHH
TIAMSLISGPLSFYILRFLLGAAEAGLYPGILYVLTKWFPLRHRARIIGLLVLAQPIALI
HHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
VTGPIAGLILSTPGAFGLSNWQVLFIVCGLPAMLLALPTLWILPASPRHARWLTPHQLSW
HHCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHH
IERELAAEKTTLKLESHSNPLRAITDRRVLLLALLFLPFPLAIYGLSLWLPTIIKQFGVS
HHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
DLAIGFLSTVPYLFAVAGLCIIPAHSDARGERHWHIVVVAALAAVTLAASAFVETPALQL
HHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFLSLAAFCIYPIQAVIWTLPGVFLTGASAAVGIATINSLANLGGYIGPYGIGLLKDATG
HHHHHHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCC
STAAGLYFLAAVLLFGVFMAFVVRASLDKTQALKSRR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SETIVNHVSRSSSRSQLRPAAMASGAHSSEERQIIGLISRKLLPFLAVIYIVAYVDRAV
CCHHHHHHHCCCCHHHCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGFAKLHMNADVGIGDAAYGLGAGLFFVGYFLCEVPSNLALERFGPRLWFARILATWGLI
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCHHHHHHHHHHHHHHH
TIAMSLISGPLSFYILRFLLGAAEAGLYPGILYVLTKWFPLRHRARIIGLLVLAQPIALI
HHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
VTGPIAGLILSTPGAFGLSNWQVLFIVCGLPAMLLALPTLWILPASPRHARWLTPHQLSW
HHCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHH
IERELAAEKTTLKLESHSNPLRAITDRRVLLLALLFLPFPLAIYGLSLWLPTIIKQFGVS
HHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
DLAIGFLSTVPYLFAVAGLCIIPAHSDARGERHWHIVVVAALAAVTLAASAFVETPALQL
HHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFLSLAAFCIYPIQAVIWTLPGVFLTGASAAVGIATINSLANLGGYIGPYGIGLLKDATG
HHHHHHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCC
STAAGLYFLAAVLLFGVFMAFVVRASLDKTQALKSRR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]