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The map label for this gene is aldH [H]

Identifier: 182679982

GI number: 182679982

Start: 3514704

End: 3516290

Strand: Reverse

Name: aldH [H]

Synonym: Bind_3078

Alternate gene names: 182679982

Gene position: 3516290-3514704 (Counterclockwise)

Preceding gene: 182679983

Following gene: 182679981

Centisome position: 84.32

GC content: 65.53

Gene sequence:

>1587_bases
ATGGCGATAAAAGGAGAGAGCCTGATCGGGAGCCGCGACGTGTCGACAGTACAGACCTTCCACGCCGTCAATCCCGCGAC
CGGCCTCACGATCGAGCCGCCCTTCGCCGAAGCAGGAGAGGCGGACGTCGAGGCCGCCGCGCAACTCGCAGCGGAAGCCT
TCCCGATCTTCCGCGAGACCACGCCATCGGCGCGCGCGGCTTTCCTTGAGGCTATCGCCGATGCGATCGAGGCGATCGGG
GATGAGCTGATCGACCGTGCCATGCAGGAAACCGGGCTGCCTAAGGCTCGCCTCACCGGCGAGCGCGGGCGGACCACGGG
GCAACTCCGGCTATTCAGCACGGTTCTTCGGCGCGGCGACTGGGTCGATGCGCGCATCGATCCCGCTTTGCCCAAACGCG
AACCTTTGCCGCGCTCCGACCTTCGAATGCGACAGATCGGCGTCGGTCCGGTGGCCGTCTTCGGCGCAAGCAACTTCCCG
CTTGCCTTCTCGGTGGCAGGGGGTGACACGGCTTCGGCGCTGGCCGCTGGCTGCCCGGTGGTGGTGAAAGGCCATCCCGC
TCATCCCGGCACTTCGGAACTGGTCGGCCGCGCCGTAAGATCGGCTGTAGAGGCCTCGGGCCTACCGGAAGGCGTCTTCT
CCCTGCTTTCGGGCACCAGCCATACACTCGGAACCTCGTTGGTCGCGGATCCGCGCATCATGGCCGTCGGCTTTACGGGC
TCAAGGGGCGGCGGCCTTGCGCTCTCGCGTATTGCCGCGCAGCGCCCGGTGCCGATCCCGGTCTATGCGGAGATGAGCAG
CATCAATCCTGTGTTTCTGCTGCCCGGCGCGCTCGCTGCAAGAGCCGATCAACTCGGCACCGCCTTCGTCGGATCCCTTA
CGCTGGGGGCGGGCCAATTCTGTACCAATCCCGGCGTGGCGATCGGCATCGCCGGCGTGGATTTCGACCGTTTCATCGCC
GCTGCCGCTGTGGCTTTGGGAGGAGCCCCCGCAGCCGCTATGCTGACACCCGGCATCGCTGACGCCTATCAGCGGGGCGT
TGACGCGCTGGCTGCTCAAGCGGCGGTGGAGGAACTGGCCCGGGGCACTGTTCCGAATGGCCCCAACGCTTGCAGGCCGG
CCCTGTTCACGACCGACGCCAAAGCCTTCTGCGCCACATCCGAGTTGTCACATGAAGTCTTCGGCGCCTCATCGCTGATC
GTGCGCTGCGCCGATAAGGAAGAGATGCAAGCCGTCGCCCGTGCGCTCGAAGGACAACTCACGGCGACTCTTCATCTCGA
ATCTGGCGACGAAACGCTTGCTCGCACACTTTTGCCAGTACTGGACGAAAAAGCGGGACGCATTCTCGCCAATGGCTGGC
CCACAGGCGTGGAAGTCTGTGATGCCATGGTGCATGGGGGGCCGTTCCCAGCCACGTCCGATCCGCGAACGACATCGGTG
GGGACGCTGGCCATTCGCCGCTTCCTGAGACCTGTCTGTTACCAGGACCTGCCACCGGCCTTGCTGCCGCCAGCCCTGCA
GCCCGACAATCCTCTTGGCTTGCCCCGGCTTGTCAATGGAAAGACCGAGCTCGGAGGGGCGCCATGA

Upstream 100 bases:

>100_bases
ATTTTCTCGCGGCCGTGCTGTTGTTCGGCGTGTTCATGGCCTTCGTCGTGCGCGCTTCGCTAGACAAAACACAGGCCCTT
AAATCAAGGAGATAAGACCT

Downstream 100 bases:

>100_bases
TTCAAGTTCTGCAACCCGGCCCGGCAGCCAGGGAAGAGACGGTGCCCCCGATCCGCCTCGCCATCGTGGGTTTTGGCAAG
ATCGCCCGCGATCAGCATGT

Product: aldehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 528; Mature: 527

Protein sequence:

>528_residues
MAIKGESLIGSRDVSTVQTFHAVNPATGLTIEPPFAEAGEADVEAAAQLAAEAFPIFRETTPSARAAFLEAIADAIEAIG
DELIDRAMQETGLPKARLTGERGRTTGQLRLFSTVLRRGDWVDARIDPALPKREPLPRSDLRMRQIGVGPVAVFGASNFP
LAFSVAGGDTASALAAGCPVVVKGHPAHPGTSELVGRAVRSAVEASGLPEGVFSLLSGTSHTLGTSLVADPRIMAVGFTG
SRGGGLALSRIAAQRPVPIPVYAEMSSINPVFLLPGALAARADQLGTAFVGSLTLGAGQFCTNPGVAIGIAGVDFDRFIA
AAAVALGGAPAAAMLTPGIADAYQRGVDALAAQAAVEELARGTVPNGPNACRPALFTTDAKAFCATSELSHEVFGASSLI
VRCADKEEMQAVARALEGQLTATLHLESGDETLARTLLPVLDEKAGRILANGWPTGVEVCDAMVHGGPFPATSDPRTTSV
GTLAIRRFLRPVCYQDLPPALLPPALQPDNPLGLPRLVNGKTELGGAP

Sequences:

>Translated_528_residues
MAIKGESLIGSRDVSTVQTFHAVNPATGLTIEPPFAEAGEADVEAAAQLAAEAFPIFRETTPSARAAFLEAIADAIEAIG
DELIDRAMQETGLPKARLTGERGRTTGQLRLFSTVLRRGDWVDARIDPALPKREPLPRSDLRMRQIGVGPVAVFGASNFP
LAFSVAGGDTASALAAGCPVVVKGHPAHPGTSELVGRAVRSAVEASGLPEGVFSLLSGTSHTLGTSLVADPRIMAVGFTG
SRGGGLALSRIAAQRPVPIPVYAEMSSINPVFLLPGALAARADQLGTAFVGSLTLGAGQFCTNPGVAIGIAGVDFDRFIA
AAAVALGGAPAAAMLTPGIADAYQRGVDALAAQAAVEELARGTVPNGPNACRPALFTTDAKAFCATSELSHEVFGASSLI
VRCADKEEMQAVARALEGQLTATLHLESGDETLARTLLPVLDEKAGRILANGWPTGVEVCDAMVHGGPFPATSDPRTTSV
GTLAIRRFLRPVCYQDLPPALLPPALQPDNPLGLPRLVNGKTELGGAP
>Mature_527_residues
AIKGESLIGSRDVSTVQTFHAVNPATGLTIEPPFAEAGEADVEAAAQLAAEAFPIFRETTPSARAAFLEAIADAIEAIGD
ELIDRAMQETGLPKARLTGERGRTTGQLRLFSTVLRRGDWVDARIDPALPKREPLPRSDLRMRQIGVGPVAVFGASNFPL
AFSVAGGDTASALAAGCPVVVKGHPAHPGTSELVGRAVRSAVEASGLPEGVFSLLSGTSHTLGTSLVADPRIMAVGFTGS
RGGGLALSRIAAQRPVPIPVYAEMSSINPVFLLPGALAARADQLGTAFVGSLTLGAGQFCTNPGVAIGIAGVDFDRFIAA
AAVALGGAPAAAMLTPGIADAYQRGVDALAAQAAVEELARGTVPNGPNACRPALFTTDAKAFCATSELSHEVFGASSLIV
RCADKEEMQAVARALEGQLTATLHLESGDETLARTLLPVLDEKAGRILANGWPTGVEVCDAMVHGGPFPATSDPRTTSVG
TLAIRRFLRPVCYQDLPPALLPPALQPDNPLGLPRLVNGKTELGGAP

Specific function: Catalyzes the oxidation of long-chain aliphatic aldehydes to acids. May be implicated in controlling luminescence as it catalyzes the oxidation of the fatty aldehyde substrate for the light-emitting reaction [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI87081896, Length=430, Percent_Identity=30.2325581395349, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87081926, Length=446, Percent_Identity=26.9058295964126, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1787250, Length=286, Percent_Identity=31.4685314685315, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1788042, Length=322, Percent_Identity=28.2608695652174, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71995613, Length=298, Percent_Identity=27.5167785234899, Blast_Score=73, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71995606, Length=307, Percent_Identity=28.0130293159609, Blast_Score=72, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6319478, Length=241, Percent_Identity=28.6307053941909, Blast_Score=67, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.4 [H]

Molecular weight: Translated: 54295; Mature: 54163

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIKGESLIGSRDVSTVQTFHAVNPATGLTIEPPFAEAGEADVEAAAQLAAEAFPIFRET
CCCCCCCCCCCCCHHHHHHHHHCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHCC
TPSARAAFLEAIADAIEAIGDELIDRAMQETGLPKARLTGERGRTTGQLRLFSTVLRRGD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHCCC
WVDARIDPALPKREPLPRSDLRMRQIGVGPVAVFGASNFPLAFSVAGGDTASALAAGCPV
CCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEECCCCCCEEEEECCCCHHHHHHCCCCE
VVKGHPAHPGTSELVGRAVRSAVEASGLPEGVFSLLSGTSHTLGTSLVADPRIMAVGFTG
EEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHCCHHCCCCEEEEEECCC
SRGGGLALSRIAAQRPVPIPVYAEMSSINPVFLLPGALAARADQLGTAFVGSLTLGAGQF
CCCCCHHHHHHHHCCCCCCEEEEHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCC
CTNPGVAIGIAGVDFDRFIAAAAVALGGAPAAAMLTPGIADAYQRGVDALAAQAAVEELA
CCCCCCEEEEECCCHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
RGTVPNGPNACRPALFTTDAKAFCATSELSHEVFGASSLIVRCADKEEMQAVARALEGQL
CCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCCE
TATLHLESGDETLARTLLPVLDEKAGRILANGWPTGVEVCDAMVHGGPFPATSDPRTTSV
EEEEEECCCHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCHH
GTLAIRRFLRPVCYQDLPPALLPPALQPDNPLGLPRLVNGKTELGGAP
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCC
>Mature Secondary Structure 
AIKGESLIGSRDVSTVQTFHAVNPATGLTIEPPFAEAGEADVEAAAQLAAEAFPIFRET
CCCCCCCCCCCCHHHHHHHHHCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHCC
TPSARAAFLEAIADAIEAIGDELIDRAMQETGLPKARLTGERGRTTGQLRLFSTVLRRGD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHCCC
WVDARIDPALPKREPLPRSDLRMRQIGVGPVAVFGASNFPLAFSVAGGDTASALAAGCPV
CCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEECCCCCCEEEEECCCCHHHHHHCCCCE
VVKGHPAHPGTSELVGRAVRSAVEASGLPEGVFSLLSGTSHTLGTSLVADPRIMAVGFTG
EEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHCCHHCCCCEEEEEECCC
SRGGGLALSRIAAQRPVPIPVYAEMSSINPVFLLPGALAARADQLGTAFVGSLTLGAGQF
CCCCCHHHHHHHHCCCCCCEEEEHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCC
CTNPGVAIGIAGVDFDRFIAAAAVALGGAPAAAMLTPGIADAYQRGVDALAAQAAVEELA
CCCCCCEEEEECCCHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
RGTVPNGPNACRPALFTTDAKAFCATSELSHEVFGASSLIVRCADKEEMQAVARALEGQL
CCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCCE
TATLHLESGDETLARTLLPVLDEKAGRILANGWPTGVEVCDAMVHGGPFPATSDPRTTSV
EEEEEECCCHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCHH
GTLAIRRFLRPVCYQDLPPALLPPALQPDNPLGLPRLVNGKTELGGAP
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8527447; 10903148 [H]