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The map label for this gene is rppH [H]

Identifier: 182679841

GI number: 182679841

Start: 3341639

End: 3342142

Strand: Reverse

Name: rppH [H]

Synonym: Bind_2930

Alternate gene names: 182679841

Gene position: 3342142-3341639 (Counterclockwise)

Preceding gene: 182679842

Following gene: 182679840

Centisome position: 80.14

GC content: 53.77

Gene sequence:

>504_bases
ATGGATTTCGGACATTATCGCCCTTGCGTCGGAATCATGCTTGTGAATCAGGAAGGGCTTGTTTTCATCGGCCGTCGGCG
CGGCAAGAAGCTTCCTGAACATCTGCGGTCGGGGCATGAATGGCAAATGCCGCAAGGCGGAATTGATGAGGGCGAAGAGC
CTTATCACGCGGCCTTGCGCGAATTGCGGGAAGAGACCAATGTTTCCTCCGCGTCACTGCTCGCCGAATTGCCTATATGG
CTGAGCTATGATCTGCCGCCTGACCTCTCCAAGCGTTCCTGGAAAGGACGGTTTCAGGGCCAAACGCAGAAATGGTTCGC
GCTGCGTTTCGATGGTCAGGAAAGCGAAATCAATATCGAAACGCCGGATGGCGGGCATAAGCCCGAATTCGATGCCTGGC
GTTGGGAAAATATTGATCGTCTGGCCGATCTCATCATTCCCTTCAAGCGCGCGGTCTATGAGCAGGTCGTGGAAAATTTC
CGCCCTTTAATCAAACTCCCATAA

Upstream 100 bases:

>100_bases
ATCAAATTGATCTGAATCGGGTCTTCGCTTTCAGGTTTGATGCTGTAGCGCATGCGGTTTGCCGCAAAATCAAGCATCAA
AATCGAGGTGAAGCACAGGC

Downstream 100 bases:

>100_bases
GGTTCATCGGCGTCGTTGCTCGAAAGGGGATGATGTCTTTGATGAGAATCAGATATCATCCTTGATGATCAGAGCCGATG
AGCGGTTCTGACTCGTTCGG

Product: NUDIX hydrolase

Products: NA

Alternate protein names: (Di)nucleoside polyphosphate hydrolase [H]

Number of amino acids: Translated: 167; Mature: 167

Protein sequence:

>167_residues
MDFGHYRPCVGIMLVNQEGLVFIGRRRGKKLPEHLRSGHEWQMPQGGIDEGEEPYHAALRELREETNVSSASLLAELPIW
LSYDLPPDLSKRSWKGRFQGQTQKWFALRFDGQESEINIETPDGGHKPEFDAWRWENIDRLADLIIPFKRAVYEQVVENF
RPLIKLP

Sequences:

>Translated_167_residues
MDFGHYRPCVGIMLVNQEGLVFIGRRRGKKLPEHLRSGHEWQMPQGGIDEGEEPYHAALRELREETNVSSASLLAELPIW
LSYDLPPDLSKRSWKGRFQGQTQKWFALRFDGQESEINIETPDGGHKPEFDAWRWENIDRLADLIIPFKRAVYEQVVENF
RPLIKLP
>Mature_167_residues
MDFGHYRPCVGIMLVNQEGLVFIGRRRGKKLPEHLRSGHEWQMPQGGIDEGEEPYHAALRELREETNVSSASLLAELPIW
LSYDLPPDLSKRSWKGRFQGQTQKWFALRFDGQESEINIETPDGGHKPEFDAWRWENIDRLADLIIPFKRAVYEQVVENF
RPLIKLP

Specific function: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1789194, Length=166, Percent_Identity=38.5542168674699, Blast_Score=106, Evalue=8e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR022927 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 19468; Mature: 19468

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFGHYRPCVGIMLVNQEGLVFIGRRRGKKLPEHLRSGHEWQMPQGGIDEGEEPYHAALR
CCCCCCCCEEEEEEECCCCEEEEECCCCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHH
ELREETNVSSASLLAELPIWLSYDLPPDLSKRSWKGRFQGQTQKWFALRFDGQESEINIE
HHHHHHCCCHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEE
TPDGGHKPEFDAWRWENIDRLADLIIPFKRAVYEQVVENFRPLIKLP
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDFGHYRPCVGIMLVNQEGLVFIGRRRGKKLPEHLRSGHEWQMPQGGIDEGEEPYHAALR
CCCCCCCCEEEEEEECCCCEEEEECCCCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHH
ELREETNVSSASLLAELPIWLSYDLPPDLSKRSWKGRFQGQTQKWFALRFDGQESEINIE
HHHHHHCCCHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEE
TPDGGHKPEFDAWRWENIDRLADLIIPFKRAVYEQVVENFRPLIKLP
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA