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The map label for this gene is acpS

Identifier: 182679395

GI number: 182679395

Start: 2785088

End: 2785510

Strand: Reverse

Name: acpS

Synonym: Bind_2443

Alternate gene names: 182679395

Gene position: 2785510-2785088 (Counterclockwise)

Preceding gene: 182679396

Following gene: 182679394

Centisome position: 66.8

GC content: 62.17

Gene sequence:

>423_bases
ATGATTATCGGCTTCGGCAATGATCTCTGCGATATCCGCCGGATCGAGGAATCACTCGCCCGGTTCGGCGAACGGTTCAT
TGCGCGCTGCTTCACGGATATCGAGCGCCGAAAGTCGGAGGGCAGGCCCTCGCGTGCGGCGTCCTATGCCAAGCGTTTCG
CGGCCAAGGAAGCTTGCGCCAAGGCGCTCGGCACTGGGCTGACACAAGGGGTTTTTTGGCGTGACATGGGGGTGGTCAAT
CTGCCCTCCGGCAAGCCGACCTTGGCCTTGACGGGGGGAGCCGCTGAGCGCCTCGCTCTTTTGACGCCGCCGGGTCTGAC
GGCGATCATCCATCTGACTCTCACCGATGAATTTCCTCTCGCGCAAGCACAGGTCATCATCGAGGCGGTGGCGAGCGAGG
CGTCCTTCCGGCCCATGACATAA

Upstream 100 bases:

>100_bases
TCATTGGCTTGCCCGAGGCGATCAGACAGATGCGAAAGGCGATGGACGCGGGCCGCGCGACATATGTCGAAAGCCAATCC
CTGCGATTGAACTGACGCCT

Downstream 100 bases:

>100_bases
AACATTTTTCATCTTTCATCATAGGCCGTGTGGCGGCCCAAGAAAGCGACCCAAGACGTTCCTGATTTTGATTCCCATTG
CATTTATACAGACGAGGAAA

Product: holo-acyl-carrier-protein synthase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MIIGFGNDLCDIRRIEESLARFGERFIARCFTDIERRKSEGRPSRAASYAKRFAAKEACAKALGTGLTQGVFWRDMGVVN
LPSGKPTLALTGGAAERLALLTPPGLTAIIHLTLTDEFPLAQAQVIIEAVASEASFRPMT

Sequences:

>Translated_140_residues
MIIGFGNDLCDIRRIEESLARFGERFIARCFTDIERRKSEGRPSRAASYAKRFAAKEACAKALGTGLTQGVFWRDMGVVN
LPSGKPTLALTGGAAERLALLTPPGLTAIIHLTLTDEFPLAQAQVIIEAVASEASFRPMT
>Mature_140_residues
MIIGFGNDLCDIRRIEESLARFGERFIARCFTDIERRKSEGRPSRAASYAKRFAAKEACAKALGTGLTQGVFWRDMGVVN
LPSGKPTLALTGGAAERLALLTPPGLTAIIHLTLTDEFPLAQAQVIIEAVASEASFRPMT

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=130, Percent_Identity=43.8461538461538, Blast_Score=80, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_BEII9 (B2II98)

Other databases:

- EMBL:   CP001016
- RefSeq:   YP_001833541.1
- GeneID:   6199669
- GenomeReviews:   CP001016_GR
- KEGG:   bid:Bind_2443
- HOGENOM:   HBG734479
- OMA:   QGVFWRD
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 15154; Mature: 15154

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIGFGNDLCDIRRIEESLARFGERFIARCFTDIERRKSEGRPSRAASYAKRFAAKEACA
CEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
KALGTGLTQGVFWRDMGVVNLPSGKPTLALTGGAAERLALLTPPGLTAIIHLTLTDEFPL
HHHHCCCCCCHHHHCCCEEECCCCCCEEEEECCCCCCEEEECCCCCEEEEEEEECCCCCH
AQAQVIIEAVASEASFRPMT
HHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MIIGFGNDLCDIRRIEESLARFGERFIARCFTDIERRKSEGRPSRAASYAKRFAAKEACA
CEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
KALGTGLTQGVFWRDMGVVNLPSGKPTLALTGGAAERLALLTPPGLTAIIHLTLTDEFPL
HHHHCCCCCCHHHHCCCEEECCCCCCEEEEECCCCCCEEEECCCCCEEEEEEEECCCCCH
AQAQVIIEAVASEASFRPMT
HHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA