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The map label for this gene is lepB [H]

Identifier: 182679394

GI number: 182679394

Start: 2784101

End: 2784907

Strand: Reverse

Name: lepB [H]

Synonym: Bind_2442

Alternate gene names: 182679394

Gene position: 2784907-2784101 (Counterclockwise)

Preceding gene: 182679395

Following gene: 182679393

Centisome position: 66.78

GC content: 54.52

Gene sequence:

>807_bases
ATGACGGAGCCGACGCGGTTGGAAGGAAAAAGCTTGGACAAGAGCATCGAGACGAAGGCCACAAAGCAAACCAGTGGGAT
TGCCGAGACGGTCAAGGTCGTCGTCCAGGCTTTGCTGATCGCCTTGGTGGTTCGCACCCTGTTGTTTCAGCCCTTCAATA
TTCCGTCAGGGTCAATGATTCCGACCTTGCTGATCGGCGATTATCTGTTCGTCTCGAAATATGCCTACGGCTATTCGAAT
CATTCACTCCCTTTCAGCCCTCCTTTGTTGCAGGGCCGTGTGTTTGGGACGCCGCCCAAGCGCGGCGATGTCGTCGTCTT
CAAACTGCCGTCCGACGGTCAGACGGATTATATCAAGCGTGTCATTGGTTTGCCGGGTGATCGCATCCAGATGCGGGACG
GACGTCTCTATATCAATGACGAACTGGTGCCGCGCGAGCCAATAGCGCCCACTCATACCGAGGATTTCTACGGTCATATG
ACGGATGTGCCGACCTACAAGGAGACCTTGCCTGGCGGCGTCACCCATACGATCATCGAAATCCAGGGCGATAAGGGTTT
CAACGACAATACACAGGTCTTTAACGTGCCGCCGGATCATTATTTCATGATGGGCGATAACCGCGACAATTCGACCGATA
GCCGTGTGTCGCCAGAAGACAAGGGCGTTGGTTATGTGCCCTTCGATAATCTTGTCGGCCGCGCTGAAATCATCTTCTTC
TCCCTCGATAAAGACACGCCCGGCTGGGCGTTCTGGAAATGGCCCTGGACGGTGCGGTGGAGCCGGATGTTCCAGTCCGT
GAAATAA

Upstream 100 bases:

>100_bases
CATTTATACAGACGAGGAAACAGGCGGGTTCTGTACCCTGGCGCTTTCACATGGTAAGAGCGGCTGTAAGACCAGGGCGG
AAGAGCCGGGAAGGATGATG

Downstream 100 bases:

>100_bases
ATGTCGAGATTCAAGCAAGATCTGGAGCCGCTCGAGACGCGCATCGGTCACCGGTTCGTGGAGGCGGATTTGCTCACCAC
GGCCCTGACCCATGTCAGCG

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MTEPTRLEGKSLDKSIETKATKQTSGIAETVKVVVQALLIALVVRTLLFQPFNIPSGSMIPTLLIGDYLFVSKYAYGYSN
HSLPFSPPLLQGRVFGTPPKRGDVVVFKLPSDGQTDYIKRVIGLPGDRIQMRDGRLYINDELVPREPIAPTHTEDFYGHM
TDVPTYKETLPGGVTHTIIEIQGDKGFNDNTQVFNVPPDHYFMMGDNRDNSTDSRVSPEDKGVGYVPFDNLVGRAEIIFF
SLDKDTPGWAFWKWPWTVRWSRMFQSVK

Sequences:

>Translated_268_residues
MTEPTRLEGKSLDKSIETKATKQTSGIAETVKVVVQALLIALVVRTLLFQPFNIPSGSMIPTLLIGDYLFVSKYAYGYSN
HSLPFSPPLLQGRVFGTPPKRGDVVVFKLPSDGQTDYIKRVIGLPGDRIQMRDGRLYINDELVPREPIAPTHTEDFYGHM
TDVPTYKETLPGGVTHTIIEIQGDKGFNDNTQVFNVPPDHYFMMGDNRDNSTDSRVSPEDKGVGYVPFDNLVGRAEIIFF
SLDKDTPGWAFWKWPWTVRWSRMFQSVK
>Mature_267_residues
TEPTRLEGKSLDKSIETKATKQTSGIAETVKVVVQALLIALVVRTLLFQPFNIPSGSMIPTLLIGDYLFVSKYAYGYSNH
SLPFSPPLLQGRVFGTPPKRGDVVVFKLPSDGQTDYIKRVIGLPGDRIQMRDGRLYINDELVPREPIAPTHTEDFYGHMT
DVPTYKETLPGGVTHTIIEIQGDKGFNDNTQVFNVPPDHYFMMGDNRDNSTDSRVSPEDKGVGYVPFDNLVGRAEIIFFS
LDKDTPGWAFWKWPWTVRWSRMFQSVK

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=298, Percent_Identity=37.9194630872483, Blast_Score=147, Evalue=5e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 30235; Mature: 30104

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS00501 SPASE_I_1 ; PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPTRLEGKSLDKSIETKATKQTSGIAETVKVVVQALLIALVVRTLLFQPFNIPSGSMI
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
PTLLIGDYLFVSKYAYGYSNHSLPFSPPLLQGRVFGTPPKRGDVVVFKLPSDGQTDYIKR
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCCCEEEEECCCCCCHHHHHH
VIGLPGDRIQMRDGRLYINDELVPREPIAPTHTEDFYGHMTDVPTYKETLPGGVTHTIIE
HHCCCCCEEEEECCEEEECCCCCCCCCCCCCCCHHHHCCCCCCCCHHHHCCCCCEEEEEE
IQGDKGFNDNTQVFNVPPDHYFMMGDNRDNSTDSRVSPEDKGVGYVPFDNLVGRAEIIFF
EECCCCCCCCCEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCEECCHHHHCCCEEEEEE
SLDKDTPGWAFWKWPWTVRWSRMFQSVK
EECCCCCCCEEEECCCEEHHHHHHHHCC
>Mature Secondary Structure 
TEPTRLEGKSLDKSIETKATKQTSGIAETVKVVVQALLIALVVRTLLFQPFNIPSGSMI
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
PTLLIGDYLFVSKYAYGYSNHSLPFSPPLLQGRVFGTPPKRGDVVVFKLPSDGQTDYIKR
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCCCEEEEECCCCCCHHHHHH
VIGLPGDRIQMRDGRLYINDELVPREPIAPTHTEDFYGHMTDVPTYKETLPGGVTHTIIE
HHCCCCCEEEEECCEEEECCCCCCCCCCCCCCCHHHHCCCCCCCCHHHHCCCCCEEEEEE
IQGDKGFNDNTQVFNVPPDHYFMMGDNRDNSTDSRVSPEDKGVGYVPFDNLVGRAEIIFF
EECCCCCCCCCEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCEECCHHHHCCCEEEEEE
SLDKDTPGWAFWKWPWTVRWSRMFQSVK
EECCCCCCCEEEECCCEEHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA